Research Topics
Species | Peter A GroblewskiSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Publications
Activation and role of the medial prefrontal cortex (mPFC) in extinction of ethanol-induced associative learning in micePeter A Groblewski
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Neurobiol Learn Mem 97:37-46. 2012..Together, these experiments indicate a role for the PL and IL subregions of the mPFC in processing changes of the EtOH-cue contingency, as well as in regulating extinction of EtOH-induced associative learning in mice...
Reference-dose place conditioning with ethanol in mice: empirical and theoretical analysisPeter A Groblewski
Department of Behavioral Neuroscience, L470, Oregon Health and Science University, Portland, OR 97239 3098, USA
Psychopharmacology (Berl) 201:97-106. 2008..A frequently expressed criticism of the conditioned place preference (CPP) procedure is that it sometimes lacks a graded dose-response curve for many drugs...
Inhibition of extracellular signal-regulated kinase (ERK) activity with SL327 does not prevent acquisition, expression, and extinction of ethanol-seeking behavior in micePeter A Groblewski
Dept of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
Behav Brain Res 217:399-407. 2011..Together, these data suggest that EtOH-related learning and EtOH reward in mice, as assessed with CPP, are not impaired by the systemically administered MEK-inhibitor SL327...
Repeated microinjections into the medial prefrontal cortex (mPFC) impair extinction of conditioned place preference in micePeter A Groblewski
Dept of Behavioral Neuroscience and Portland Alcohol Research Center, Oregon Health and Science University, Portland, OR 97239, United States
Behav Brain Res 230:299-303. 2012..Consistent with recently reported effects of mPFC lesions, these data suggest that extinction was impaired by excessive mPFC damage induced by repeated intracranial infusions...
Effects of D-cycloserine on extinction and reconditioning of ethanol-seeking behavior in micePeter A Groblewski
Department of Behavioral Neuroscience and Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon
Alcohol Clin Exp Res 33:772-82. 2009..Thus, the current experiments examined the effects of DCS on the extinction and subsequent reconditioning of ethanol-induced CPP in mice...
Drug-induced conditioned place preference and aversion in miceChristopher L Cunningham
Department of Behavioral Neuroscience and Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
Nat Protoc 1:1662-70. 2006..Potential problems in the design and interpretation of place conditioning studies are discussed. A typical experiment lasts 2 weeks...
