Allison Gregory

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. doi request reprint Genetics of neurodegeneration with brain iron accumulation
    Allison Gregory
    Department of Molecular and Medical Genetics, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, mailcode L103, Portland, OR 97239 3098, USA
    Curr Neurol Neurosci Rep 11:254-61. 2011
  2. pmc Clinical and genetic delineation of neurodegeneration with brain iron accumulation
    A Gregory
    Molecular and Medical Genetics, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    J Med Genet 46:73-80. 2009
  3. pmc β-Propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation
    Susan J Hayflick
    Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
    Brain 136:1708-17. 2013
  4. pmc Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration
    Michael C Kruer
    Division of Developmental Paediatrics, Child Development and Rehabilitation Centre, Oregon Health and Science University, Portland, OR 97239, USA
    Brain 134:947-58. 2011
  5. pmc Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome)
    Robert A Egan
    Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland 97201, USA
    Am J Ophthalmol 140:267-74. 2005
  6. pmc Intellectual and adaptive behaviour functioning in pantothenate kinase-associated neurodegeneration
    K Freeman
    Child Development and Rehabilitation Center, Portland, OR, USA
    J Intellect Disabil Res 51:417-26. 2007
  7. pmc New NBIA subtype: genetic, clinical, pathologic, and radiographic features of MPAN
    Penelope Hogarth
    Department of Neurology, Oregon Health and Science University, Portland, USA
    Neurology 80:268-75. 2013
  8. doi request reprint Metabolism and energy requirements in pantothenate kinase-associated neurodegeneration
    Sarah Williams
    Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, USA
    Mol Genet Metab 110:336-41. 2013
  9. pmc Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts
    Michael C Kruer
    Sanford Children s Health Research Center, Sioux Falls, SD 57104, USA
    Neurosci Lett 523:35-8. 2012
  10. doi request reprint Defective FA2H leads to a novel form of neurodegeneration with brain iron accumulation (NBIA)
    Michael C Kruer
    Division of Developmental Pediatrics, Child Development and Rehabilitation Center, Oregon Health and Science University, Portland, OR 97239, USA
    Ann Neurol 68:611-8. 2010

Detail Information

Publications12

  1. doi request reprint Genetics of neurodegeneration with brain iron accumulation
    Allison Gregory
    Department of Molecular and Medical Genetics, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, mailcode L103, Portland, OR 97239 3098, USA
    Curr Neurol Neurosci Rep 11:254-61. 2011
    ..Continued investigations of the underlying pathogenesis of disease, with a focus on lipid, iron, and energy metabolism, will lead to the identification of new therapeutic targets...
  2. pmc Clinical and genetic delineation of neurodegeneration with brain iron accumulation
    A Gregory
    Molecular and Medical Genetics, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    J Med Genet 46:73-80. 2009
    ..High brain iron is also present in a portion of these cases. Clinical assessment, neuroimaging, and molecular genetic testing all play a role in guiding the diagnostic evaluation and treatment of NBIA...
  3. pmc β-Propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation
    Susan J Hayflick
    Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
    Brain 136:1708-17. 2013
    ....
  4. pmc Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration
    Michael C Kruer
    Division of Developmental Paediatrics, Child Development and Rehabilitation Centre, Oregon Health and Science University, Portland, OR 97239, USA
    Brain 134:947-58. 2011
    ..In so doing, we characterize fundamental features of the disease and redefine its nosological relationship to other neurodegenerative disorders...
  5. pmc Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome)
    Robert A Egan
    Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland 97201, USA
    Am J Ophthalmol 140:267-74. 2005
    ..Since the neuro-ophthalmologic and electroretinographic (ERG) features have never been well delineated, we describe them in 16 patients with PKAN...
  6. pmc Intellectual and adaptive behaviour functioning in pantothenate kinase-associated neurodegeneration
    K Freeman
    Child Development and Rehabilitation Center, Portland, OR, USA
    J Intellect Disabil Res 51:417-26. 2007
    ..Investigations of cognitive functioning have utilized specific neuropsychological tests, without attention to general intellectual skills or adaptive behaviour...
  7. pmc New NBIA subtype: genetic, clinical, pathologic, and radiographic features of MPAN
    Penelope Hogarth
    Department of Neurology, Oregon Health and Science University, Portland, USA
    Neurology 80:268-75. 2013
    ..To assess the frequency of mutations in C19orf12 in the greater neurodegeneration with brain iron accumulation (NBIA) population and further characterize the associated phenotype...
  8. doi request reprint Metabolism and energy requirements in pantothenate kinase-associated neurodegeneration
    Sarah Williams
    Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, USA
    Mol Genet Metab 110:336-41. 2013
    ..We did observe increased resting energy expenditure associated with disease severity, suggesting increased energy needs later in the disease process, and elevated urinary mevalonate levels. ..
  9. pmc Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts
    Michael C Kruer
    Sanford Children s Health Research Center, Sioux Falls, SD 57104, USA
    Neurosci Lett 523:35-8. 2012
    ..Our results indicate that ATP13A2 mutations are a rare cause of both NBIA and dystonia-parkinsonism...
  10. doi request reprint Defective FA2H leads to a novel form of neurodegeneration with brain iron accumulation (NBIA)
    Michael C Kruer
    Division of Developmental Pediatrics, Child Development and Rehabilitation Center, Oregon Health and Science University, Portland, OR 97239, USA
    Ann Neurol 68:611-8. 2010
    ..Here we report the discovery of a novel gene that leads to a distinct form of NBIA...
  11. pmc Neurodegeneration with brain iron accumulation
    Allison Gregory
    Department of Molecular and Medical Genetics, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd L103A, Portland, Oregon 97239, USA
    Folia Neuropathol 43:286-96. 2005
    ..Identification of the major NBIA gene has led to more accurate clinical delineation of the diseases that comprise this group, a molecular diagnostic test for PKAN, and hypotheses for treatment...
  12. pmc Neurodegeneration associated with genetic defects in phospholipase A(2)
    A Gregory
    Department of Molecular and Medical Genetics, Oregon Health and Science University, L103A, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 3098, USA
    Neurology 71:1402-9. 2008
    ..We sought to delineate the clinical, radiographic, pathologic, and genetic features of disease resulting from defective phospholipase A(2)...