Research Topics
| Frederick Web FraunfelderSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Detail Information
Publications
Treatment of recurrent corneal erosion by extended-wear bandage contact lensFrederick W Fraunfelder
Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland, OR, USA
Cornea 30:164-6. 2011..To assess the efficacy of using a bandage contact lens (BCL) for 3 months for recurrent corneal erosions (RCE) to facilitate epithelial adhesion...
Ocular adverse drug reactions and the National Registry of Drug-Induced Ocular Side EffectsF W Fraunfelder
Casey Eye Institute, Portland, OR 97201-4197, USA
Insight 29:7-11. 2004
Ocular side effects associated with dietary supplements and herbal medicinesFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
Drugs Today (Barc) 41:537-45. 2005..In most instances, stopping the treatment or decreasing the dose allows for full resolution of symptoms. In addition, comment is made on the regulatory confusion that exists for this industry, especially in the United States...
Liquid nitrogen cryotherapy of advancing wavelike epitheliopathyFrederick Web Fraunfelder
The Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Cornea 25:196-8. 2006..To describe a method for treating advancing wavelike epitheliopathy (AWE) with liquid nitrogen cryotherapy spray...
Ocular adverse effects associated with cyclooxygenase-2 inhibitorsFrederick W Fraunfelder
Casey Eye Institute, Portland, OR 97201, USA
Arch Ophthalmol 124:277-9. 2006
Corneal toxicity from topical ocular and systemic medicationsF W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239 4197, USA
Cornea 25:1133-8. 2006..To review what is known about the adverse effects on the cornea from various classes of medications. New data from previously unreported cases of drug-related corneal toxicity are included...
Drug-induced ocular inflammatory diseasesFrederick W Fraunfelder
The National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Drugs Today (Barc) 43:117-23. 2007..Prevention and treatment are based upon physician recognition and withdrawal of the drug in some instances. Consultation with an ophthalmologist is recommended, as many types of ocular inflammation can threaten vision...
Peripheral ulcerative keratitis-like findings associated with filgrastimFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239 4197, USA
Cornea 26:368-9. 2007..To describe an ocular side effect occurring with filgrastim therapy...
Central serous chorioretinopathy associated with sildenafilFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239 4197, USA
Retina 28:606-9. 2008..To investigate a suspected relationship between central serous chorioretinopathy (CSC) and sildenafil therapy...
Liquid nitrogen cryotherapy of superior limbic keratoconjunctivitisFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Am J Ophthalmol 147:234-238.e1. 2009..To evaluate the effects of liquid nitrogen cryotherapy on superior limbic keratoconjunctivitis (SLK)...
Diplopia, blepharoptosis, and ophthalmoplegia and 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor useF W Fraunfelder
Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Ophthalmology 115:2282-5. 2008..To report the association between 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) and diplopia, blepharoptosis (ptosis), and ophthalmoplegia...
Liquid nitrogen cryotherapy of lymphangiectasiaFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239 4197, USA
Cornea 28:594-6. 2009..To report a case of lymphangiectasia successfully treated with liquid nitrogen cryotherapy...
Liquid nitrogen cryotherapy for conjunctival amyloidosisFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239 4197, USA
Arch Ophthalmol 127:645-8. 2009..Although surgical debulking is the usual treatment for this disease, liquid nitrogen cryotherapy to the ocular surface seems to be a safe and effective adjunct or alternative treatment...
Interferon alfa-associated anterior ischemic optic neuropathyF W Fraunfelder
Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Ophthalmology 118:408-11.e1-2. 2011..To report a possible association between interferon alfa therapy and anterior ischemic optic neuropathy (AION)...
Scientific challenges in postmarketing surveillance of ocular adverse drug reactionsFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239, USA
Am J Ophthalmol 143:145-149. 2007..To highlight the challenges of postmarketing surveillance for drug-related adverse events in the practice of ophthalmology...
Ocular side effects from herbal medicines and nutritional supplementsFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland 97239 4197, USA
Am J Ophthalmol 138:639-47. 2004..World Health Organization (WHO) classification and guidelines for clinicians are provided...
Ocular adverse drug reactionsF W Fraunfelder
Casey Eye Institute and the National Registry of Drug Induced Ocular Side Effects, 3375 SW Terwilliger Boulevard, Portland, OR 97201 4197, USA
Expert Opin Drug Saf 2:411-20. 2003..Ocular side effects of clinical importance are highlighted with guidelines for recognition, reporting and treatment of adverse drug reactions (ADRs). The current and future status of pharmacovigilance in ocular toxicology is addressed...
Ocular side effects associated with isotretinoinFrederick W Fraunfelder
National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97201 4197, USA
Drugs Today (Barc) 40:23-7. 2004..Ocular sicca, decreased dark adaptation and intracranial hypertension are identified as "certain" side effects from isotretinoin and clinicians are provided guidelines for care and follow-up...
Diplopia and fluoroquinolonesFrederick W Fraunfelder
Department of Ophthalmology Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239, USA
Ophthalmology 116:1814-7. 2009..To report a possible association between fluoroquinolones and diplopia...
Oculogyric crisis in patients taking cetirizineFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97201, USA
Am J Ophthalmol 137:355-7. 2004..To report oculogyric crisis in patients receiving cetirizine and inform clinicians on the characteristics of this drug-induced ocular side effect...
Ocular hemorrhage possibly the result of HMG-CoA reductase inhibitorsF W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97201, USA
J Ocul Pharmacol Ther 20:179-82. 2004..Some patients also received medications known to increase bleeding times. From the collected data, ocular hemorrhage is "possibly" due to statin therapy...
Isotretinoin-associated intracranial hypertensionFrederick W Fraunfelder
University of Mississippi School of Medicine Neurology Department, Jackson, Mississippi, USA
Ophthalmology 111:1248-50. 2004..To evaluate the association between intracranial hypertension (IH) and isotretinoin use...
Ocular side-effects associated with imatinib mesylate (Gleevec)Frederick W Fraunfelder
Casey Eye Institute, Portland OR 97201, USA
J Ocul Pharmacol Ther 19:371-5. 2003..Clinical characteristics of imatinib mesylate induced periorbital edema are described. Management of ocular side-effects is conservative except in very rare cases of visually significant periorbital edema...
Adverse ocular drug reactions recently identified by the National Registry of Drug-Induced Ocular Side EffectsF W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
Ophthalmology 111:1275-9. 2004..To report recent ocular adverse drug reactions identified by the National Registry of Drug-Induced Ocular Side Effects...
Evidence for a probable causal relationship between tretinoin, acitretin, and etretinate and intracranial hypertensionFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97201, USA
J Neuroophthalmol 24:214-6. 2004..Even so, the data suggest that all retinoids may, in rare instances, cause intracranial hypertension...
Liquid nitrogen cryotherapy for surface eye disease (an AOS thesis)Frederick Web Fraunfelder
Department of Ophthalmology Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Trans Am Ophthalmol Soc 106:301-24. 2008..To evaluate the effects of new treatments with liquid nitrogen cryotherapy on some external eye conditions...
Drug-induced optic neuropathiesMichael J Lloyd
Casey Eye Institute, Portland, Oregon, USA
Drugs Today (Barc) 43:827-36. 2007..The most important aspect of treatment is identification of the offending agent and prompt drug withdrawal. Where there is consensus, we will present guidelines on screening for and managing the various drug-induced optic neuropathies...
Adverse ocular effects from over-the-counter lice shampooFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97201, USA
Arch Ophthalmol 121:1790-1. 2003
Scleritis and other ocular side effects associated with pamidronate disodiumFrederick W Fraunfelder
Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon, USA
Am J Ophthalmol 135:219-22. 2003..To evaluate reported cases of scleritis and other ocular side effects associated with pamidronate disodium, with emphasis on previously unreported cases of scleritis...
Possible adverse effects of drugs used in refractive surgeryFrederick W Fraunfelder
Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon 97201, USA
J Cataract Refract Surg 29:170-5. 2003..Physicians should be aware of the side-effect profile and current industry standards for medications used in corneal refractive surgery, including off-label uses. Guidelines are provided for some classes of medications...
Laser-assisted in situ keratomileusis complications in diabetes mellitusFrederick W Fraunfelder
Cornea Service, Casey Eye Institute, Portland, Oregon, USA
Cornea 21:246-8. 2002..To report the incidence of complications and the refractive results in patients with diabetes mellitus treated with laser-assisted in situ keratomileusis (LASIK)...
Epinastine hydrochloride for atopic diseaseFrederick W Fraunfelder
National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Drugs Today (Barc) 40:677-83. 2004..This drug is marketed as having very few CNS-depressant side effects, few drug interactions and gastrointestinal side effects, and a low risk of cardiotoxicity...
Liquid nitrogen cryotherapy for conjunctival lymphangiectasia: a case seriesFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Trans Am Ophthalmol Soc 107:229-32. 2009..To report a case series of conjunctival lymphangiectasia treated with liquid nitrogen cryotherapy...
Adverse systemic effects from pledgets of topical ocular phenylephrine 10%Frederick W Fraunfelder
Casey Eye Institute, Oregon Health Sciences University, Portland 097201, USA
Am J Ophthalmol 134:624-5. 2002....
Twice-yearly exams unnecessary for patients taking quetiapineFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Am J Ophthalmol 138:870-1. 2004..Also, to explore the possibility of cataractogenesis because of quetiapine therapy...
Update on ethambutol optic neuropathyFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, 3375 S W Terwilliger Boulevard, Portland, OR 97239 4197, USA
Expert Opin Drug Saf 5:615-8. 2006..In addition, new treatment recommendations are suggested to assist clinicians in complying with currently accepted standards of care...
Laser in situ keratomileusis using the Nidek EC-5000 or the Alcon LADARVision 4000 systemsFrederick W Fraunfelder
Casey Eye Institute, 3375 SW Terwilliger Blvd, Portland, OR 97201, USA
J Refract Surg 20:127-31. 2004..To compare the refractive results of eyes with low to moderate myopia that underwent laser in situ keratomileusis with either the Nidek EC-5000 or the Alcon LADARVision 4000 excimer laser systems...
Pegaptanib for wet macular degenerationFrederick W Fraunfelder
National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Drugs Today (Barc) 41:703-9. 2005..Research in the field of macular degeneration is advancing rapidly, and treatment with an aptamer such as pegaptanib is a viable option despite the possibility of adverse events...
Visual side effects associated with erectile dysfunction agentsFrederick W Fraunfelder
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
Am J Ophthalmol 140:723-4. 2005..To describe the known ocular side effects of agents used to treat erectile dysfunction...
Hepatitis B vaccine and uveitis: an emerging hypothesis suggested by review of 32 case reportsFrederick W Fraunfelder
Casey Eye Institute, Portland, Oregon 97239, USA
Cutan Ocul Toxicol 29:26-9. 2010..To report a possible association between hepatitis B vaccine and uveitis...
Comparison of femtosecond laser-assisted keratoplasty versus conventional penetrating keratoplastyWinston D Chamberlain
Department of Ophthalmology Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
Ophthalmology 118:486-91. 2011..To compare postoperative outcomes for femtosecond laser-assisted keratoplasty (FLAK) with conventional penetrating keratoplasty (PK)...
Ocular adverse effects associated with systemic medications : recognition and managementRicardo M Santaella
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97201, USA
Drugs 67:75-93. 2007..It is the role of all healthcare professionals to detect, treat and educate the public about adverse reactions to medications as they are an important health problem...
B-Cells in ocular adnexal lymphoproliferative lesions express B-cell attracting chemokine 1 (CXCL13)Katherine M Falkenhagen
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239-4197, USA
Am J Ophthalmol 140:335-7. 2005..CONCLUSIONS: B-cells in ocular adnexal lymphoproliferative lesions demonstrate expression of CXCL13, a chemokine that may participate in tumor pathogenesis and is a potential target for novel therapies...
Ocular side effects associated with bisphosphonatesFrederick W Fraunfelder
National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97201 4197, USA
Drugs Today (Barc) 39:829-35. 2003..Recognition of adverse ocular events in association with bisphosphonate therapy should alert clinicians to the need for ophthalmic evaluation and the consideration of discontinuation of therapy in all cases of scleritis...
