DEBORAH ANN FINN

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Rewarding effect of the neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in mice
    D A Finn
    Dept of Veteran Affairs Medical Center Portland, OR 97201, USA
    Pharmacol Biochem Behav 56:261-4. 1997
  2. ncbi request reprint A new look at the 5alpha-reductase inhibitor finasteride
    Deborah A Finn
    Department of Veterans Affairs Medical Research, Portland Alcohol Research Center, 97239, USA
    CNS Drug Rev 12:53-76. 2006
  3. ncbi request reprint Selected line difference in sensitivity to a GABAergic neurosteroid during ethanol withdrawal
    D A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Oregon Health and Science University, Portland, OR 97239, USA
    Genes Brain Behav 5:53-63. 2006
  4. doi request reprint Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice
    Deborah A Finn
    VAMC Research R and D 49, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 201:423-33. 2008
  5. ncbi request reprint A procedure to produce high alcohol intake in mice
    Deborah A Finn
    Portland Alcohol Research Center, VAMC Research and Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Psychopharmacology (Berl) 178:471-80. 2005
  6. pmc Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors
    Deborah A Finn
    Department of Veterans Affairs Medical Research, Portland, OR 97239, USA
    Horm Behav 57:12-22. 2010
  7. ncbi request reprint Interaction of chronic ethanol exposure and finasteride: sex and strain differences
    Deborah A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, VAMC Research R and D 49, 3710 SW U S Veterans Hospital Road, Portland, OR 97239, USA
    Pharmacol Biochem Behav 78:435-43. 2004
  8. ncbi request reprint Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice
    D A Finn
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Neuroscience 123:813-9. 2004
  9. ncbi request reprint Neurosteroid consumption has anxiolytic effects in mice
    Deborah A Finn
    Department of Veterans Affairs Medical Center, Portland Alcohol Research Center, 3710 SW U S Veterans Hospital Road, Portland, OR 97239, USA
    Pharmacol Biochem Behav 76:451-62. 2003
  10. ncbi request reprint Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)
    Deborah A Finn
    Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon Veterans Affairs Medical Center, Oregon, USA
    Alcohol Clin Exp Res 31:939-49. 2007

Detail Information

Publications49

  1. ncbi request reprint Rewarding effect of the neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in mice
    D A Finn
    Dept of Veteran Affairs Medical Center Portland, OR 97201, USA
    Pharmacol Biochem Behav 56:261-4. 1997
    ..These results provide the first demonstration that 3 alpha,5 alpha-P, an endogenous modulator of GABAA receptor function, possesses rewarding properties using the conditioned place preference paradigm...
  2. ncbi request reprint A new look at the 5alpha-reductase inhibitor finasteride
    Deborah A Finn
    Department of Veterans Affairs Medical Research, Portland Alcohol Research Center, 97239, USA
    CNS Drug Rev 12:53-76. 2006
    ..The data suggest that endogenous neuroactive steroid levels may be inversely related to symptoms of premenstrual and postpartum dysphoric disorder, catamenial epilepsy, depression, and alcohol withdrawal...
  3. ncbi request reprint Selected line difference in sensitivity to a GABAergic neurosteroid during ethanol withdrawal
    D A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Oregon Health and Science University, Portland, OR 97239, USA
    Genes Brain Behav 5:53-63. 2006
    ..These findings suggest that mice selectively bred for differences in EtOH withdrawal severity are differentially sensitive to ALLO during EtOH withdrawal...
  4. doi request reprint Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice
    Deborah A Finn
    VAMC Research R and D 49, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 201:423-33. 2008
    ..However, the neurochemical basis for reinstatement of responding following extinction has not been examined in mice with this model...
  5. ncbi request reprint A procedure to produce high alcohol intake in mice
    Deborah A Finn
    Portland Alcohol Research Center, VAMC Research and Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Psychopharmacology (Berl) 178:471-80. 2005
    ....
  6. pmc Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors
    Deborah A Finn
    Department of Veterans Affairs Medical Research, Portland, OR 97239, USA
    Horm Behav 57:12-22. 2010
    ..Thus, sex differences in the modulation of GABAergic neurosteroids may be an important consideration in understanding and developing therapeutic interventions in alcoholics...
  7. ncbi request reprint Interaction of chronic ethanol exposure and finasteride: sex and strain differences
    Deborah A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, VAMC Research R and D 49, 3710 SW U S Veterans Hospital Road, Portland, OR 97239, USA
    Pharmacol Biochem Behav 78:435-43. 2004
    ..Finasteride pretreatment significantly decreased blood EtOH concentration (BEC) upon initiation of withdrawal, suggesting that finasteride may affect withdrawal severity via an alteration in EtOH pharmacokinetics...
  8. ncbi request reprint Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice
    D A Finn
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Neuroscience 123:813-9. 2004
    ..These results have important implications for studies investigating the potential role of endogenous allopregnanolone levels in modulating susceptibility to ethanol abuse...
  9. ncbi request reprint Neurosteroid consumption has anxiolytic effects in mice
    Deborah A Finn
    Department of Veterans Affairs Medical Center, Portland Alcohol Research Center, 3710 SW U S Veterans Hospital Road, Portland, OR 97239, USA
    Pharmacol Biochem Behav 76:451-62. 2003
    ....
  10. ncbi request reprint Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)
    Deborah A Finn
    Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon Veterans Affairs Medical Center, Oregon, USA
    Alcohol Clin Exp Res 31:939-49. 2007
    ..The present studies provide additional behavioral validation and initial pharmacological validation of this withdrawal-associated drinking procedure...
  11. ncbi request reprint Differential change in neuroactive steroid sensitivity during ethanol withdrawal
    D A Finn
    Portland Alcohol Research Center, Research Service, Veterans Affairs Medical Center and Department of Behavioral Neuroscience, Oregon Health Sciences University, Portland, OR 97201, USA
    J Pharmacol Exp Ther 292:394-405. 2000
    ..These results suggest that sensitization to the anticonvulsant effect of 3alpha,5alpha-P during EtOH withdrawal does not generalize across all genotypes nor does it generalize to all of the pharmacological effects of 3alpha,5alpha-P...
  12. ncbi request reprint The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches
    Deborah A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Pharmacol Ther 101:91-112. 2004
    ....
  13. ncbi request reprint Chronic ethanol differentially alters susceptibility to chemically induced convulsions in withdrawal seizure-prone and -resistant mice
    D A Finn
    Portland Alcohol Research Center, Department of Veterans Affairs, Oregon 97201, USA
    J Pharmacol Exp Ther 288:782-90. 1999
    ..This supports a role for EAA systems in determining genetic susceptibility to alcohol withdrawal...
  14. ncbi request reprint Genetic animal models of anxiety
    Deborah A Finn
    Department of Veterans Affairs Medical Center, Oregon Health and Science University, Portland, OR 97239 USA
    Neurogenetics 4:109-35. 2003
    ..Expression array technologies have as yet not been employed, but can be expected to implicate novel candidates and neurobiological pathways...
  15. pmc Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice
    Ethan H Beckley
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
    Neuropharmacology 54:365-74. 2008
    ....
  16. pmc Ethanol intake patterns in female mice: influence of allopregnanolone and the inhibition of its synthesis
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Drug Alcohol Depend 97:73-85. 2008
    ..In conjunction with data in male mice, the present findings indicate that there are sex differences in the physiological regulation of ethanol intake patterns by GABAergic neurosteroids...
  17. ncbi request reprint Cocaine self-administration alters the locomotor response to microinjection of bicuculline into the ventral tegmental area of rats
    Michele C Grubb
    Department of Behavioral Neuroscience L470, Oregon Health and Science University, 3181 SW Sam Johnson Park Road, Portland, OR 97201, USA
    Brain Res 952:44-51. 2002
    ....
  18. ncbi request reprint Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice
    Rachna S Sinnott
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University and Department of Veterans Affairs Medical Center, Portland, OR 97201, USA
    Psychopharmacology (Berl) 162:438-47. 2002
    ..Recent findings indicate that ethanol (EtOH) and ALLOP share common mechanisms of action and that ALLOP may modulate some of EtOH's abuse-related effects...
  19. ncbi request reprint Reinforcing effects of the neurosteroid allopregnanolone in rats
    Rachna S Sinnott
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97201, USA
    Pharmacol Biochem Behav 72:923-9. 2002
    ....
  20. pmc Voluntary ethanol consumption in 22 inbred mouse strains
    Naomi Yoneyama
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Alcohol 42:149-60. 2008
    ..37-0.45). These results add new strains to the strain mean database that will facilitate the identification of genetic relationships between voluntary ethanol consumption, saccharin preference, and other phenotypes...
  21. pmc Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
    Ethan H Beckley
    Oregon Health and Science University, Department of Behavioral Neuroscience, School of Medicine, Mail Code L 470, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 3098, United States
    Pharmacol Biochem Behav 87:412-9. 2007
    ..Future studies of PWD may provide information about human conditions that are associated with hormone changes such as premenstrual syndrome or postpartum depression...
  22. pmc The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol
    Katherine R Gililland
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    Alcohol Clin Exp Res 31:1846-57. 2007
    ..Thus, the purpose of the present study was to determine the impact of removal of the adrenals and/or gonads on withdrawal severity following a single high dose of ethanol in 2 genotypes that differ in ethanol withdrawal severity...
  23. pmc "Binge" drinking experience in adolescent mice shows sex differences and elevated ethanol intake in adulthood
    Moriah N Strong
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Horm Behav 58:82-90. 2010
    ..Thus, adolescent binge drinking significantly increased unlimited ethanol intake during adulthood, with female mice more susceptible to this effect...
  24. pmc Sex differences in acute ethanol withdrawal severity after adrenalectomy and gonadectomy in Withdrawal Seizure-Prone and Withdrawal Seizure-Resistant mice
    Moriah N Strong
    Department of Behavioral Neuroscience, Oregon Health and Science University, VAMC Research R and D 49, Portland, OR 97239, USA
    Alcohol 43:367-77. 2009
    ....
  25. pmc The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice
    Katherine R Gililland-Kaufman
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Brain Res 1243:113-23. 2008
    ....
  26. pmc Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking
    Michelle A Tanchuck
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Alcohol 45:33-44. 2011
    ..MPEP (10 mg/kg) significantly decreased binge alcohol consumption and sucrose self-administration. These results indicate that manipulation of the opioidergic, glutamatergic, and GABAergic systems significantly decreased binge drinking...
  27. pmc The influence of selection for ethanol withdrawal severity on traits associated with ethanol self-administration and reinforcement
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, 97239 3098, USA
    Alcohol Clin Exp Res 35:326-37. 2011
    ....
  28. pmc A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication
    John C Crabbe
    Portland Alcohol Research Center, Portland, Oregon, USA
    Biol Psychiatry 65:662-70. 2009
    ..We report progress toward the development of a new genetic animal model for high levels of alcohol drinking...
  29. pmc Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Alcohol Clin Exp Res 32:1408-16. 2008
    ..The primary aim of the current work was to determine whether FIN would reduce the acquisition of drinking in ethanol-naïve mice...
  30. pmc Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression
    Michelle A Tanchuck
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Alcohol Clin Exp Res 33:2077-87. 2009
    ....
  31. pmc Influence of reinforcement schedule on ethanol consumption patterns in non-food restricted male C57BL/6J mice
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Alcohol 41:21-9. 2007
    ..These results suggest that the separation of appetitive and consummatory phases of ethanol self-administration may prove useful in future evaluations of the pharmacological and genetic bases of ethanol reinforcement in mice...
  32. ncbi request reprint Allopregnanolone does not influence ethanol-induced conditioned place preference in DBA/2J mice
    Kara I Gabriel
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Psychopharmacology (Berl) 176:50-6. 2004
    ....
  33. ncbi request reprint Effects of finasteride on chronic and acute ethanol withdrawal severity in the WSP and WSR selected lines
    Rebecca E Gorin
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, Oregon 97239, USA
    Alcohol Clin Exp Res 29:939-48. 2005
    ..Using the Withdrawal Seizure-Prone (WSP) and Withdrawal Seizure-Resistant (WSR) selected lines, in the present studies we examined the effect of finasteride on acute and chronic EtOH withdrawal severity...
  34. ncbi request reprint Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, VAMC Research R and D 12, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 169:190-7. 2003
    ..Anxiety is a common disorder in humans that exists in many forms, and animal models of human anxiety are typically employed for the discovery of anxiolytic drugs with human therapeutic potential...
  35. pmc Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J mice
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, the Portland Alcohol Research Center, and Veterans Affairs Medical Center Research, Portland, Oregon 97239 3098, USA
    Alcohol Clin Exp Res 29:1630-40. 2005
    ..The purpose of this study was to evaluate the impact of exogenous neurosteroid challenges with the agonist ALLO and the partial agonist/antagonist epipregnanolone (EPI) on the microarchitecture of ethanol drinking patterns...
  36. ncbi request reprint Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice
    Justin S Rhodes
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, and VA Medical Center, Portland, Oregon 97239, USA
    Physiol Behav 84:53-63. 2005
    ..We discuss advantages of the model for high-throughput screening assays where the goal is to find other genotypes of mice that drink excessively, or to screen drugs for their efficacy in blocking excessive drinking...
  37. ncbi request reprint Impact of sex: determination of alcohol neuroadaptation and reinforcement
    Kristine M Wiren
    Oregon Health and Science University, VA Medical Center, Portland, Oregon 97239 2964, USA
    Alcohol Clin Exp Res 30:233-42. 2006
    ..Devaud; (3) The Influence of Sex on Ethanol Consumption and Reward in C57BL/6 Mice, by Kimber L. Price and Lawrence D. Middaugh; and (4) Sex Differences in Alcohol Self-administration in Cynomolgus Monkeys, by Kathleen A. Grant...
  38. pmc Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Alcohol 37:23-33. 2005
    ....
  39. pmc The influence of mecamylamine on ethanol and sucrose self-administration
    Matthew M Ford
    Department of Behavioral Neuroscience L 470, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Neuropharmacology 57:250-8. 2009
    ..Assessment of drinking topography within an operant self-administration procedure may provide useful insights regarding the role of nAChR function in the regulation of ethanol consumption...
  40. pmc Injection of oxotremorine in nucleus accumbens shell reduces cocaine but not food self-administration in rats
    Gregory P Mark
    Department of Behavioral Neuroscience, L 470, Oregon Health and Science University, School of Medicine, 3181 S W Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Brain Res 1123:51-9. 2006
    ..1, 0.3 and 1.0 nmol/side) injection in the NAcc did not affect BP for food reward. The results suggest that muscarinic ACh receptors in the caudomedial NAcc may play a role in mediating the behavior reinforcing effects of cocaine...
  41. ncbi request reprint The relationship between hippocampal acetylcholine release and cholinergic convulsant sensitivity in withdrawal seizure-prone and withdrawal seizure-resistant selected mouse lines
    Gregory P Mark
    Department of Behavioral Neuroscience, School of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Alcohol Clin Exp Res 26:1141-52. 2002
    ..Thus, the relationship between cholinergic activity and responsiveness and alcohol withdrawal was investigated in a genetic animal model of ethanol withdrawal severity...
  42. pmc Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice
    Matthew M Ford
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Behav Brain Res 179:265-72. 2007
    ..These findings support the premise that manipulations in brain ALLO levels may influence the regulatory processes governing ethanol consumption...
  43. ncbi request reprint Electrolytic lesions of the medial nucleus accumbens shell selectively decrease ethanol consumption without altering preference in a limited access procedure in C57BL/6J mice
    Ronnie Dhaher
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, United States
    Pharmacol Biochem Behav 92:335-42. 2009
    ..These results suggest that the MNAc shell is a component of the underlying neural circuitry contributing to limited access alcohol consumption in the B6 mouse...
  44. ncbi request reprint New neuronal networks involved in ethanol reinforcement
    Kalervo Kiianmaa
    Department of Mental Helath and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Alcohol Clin Exp Res 27:209-19. 2003
    ..Finn, and (6) Potential contribution of the urocortin system to regulation of alcohol self-administration, by Andrey E. Ryabinin and Ryan K. Bachtell.(B)..
  45. pmc Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis
    Megan K Mulligan
    Waggoner Center for Alcohol and Addiction Research and Sections of Neurobiology, University of Texas, Austin, TX 78712, USA
    Proc Natl Acad Sci U S A 103:6368-73. 2006
    ..The present study demonstrates the use of (i) a microarray meta-analysis to analyze a behavioral phenotype (in this case, alcohol preference) and (ii) a congenic strain for identification of cis regulation...
  46. ncbi request reprint Neuroactive steroids and ethanol
    Robert H Purdy
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Alcohol Clin Exp Res 29:1292-8. 2005
  47. pmc Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice
    Yuri A Blednov
    Waggoner Center for Alcohol and Addictions Research, University of Texas, Austin, TX 78712 0159, USA
    Alcohol Clin Exp Res 29:1949-58. 2005
    ..No strain has been found to consume more ethanol than B6. In one of our laboratories (Texas), we noted a markedly greater intake of ethanol in an F1 hybrid of B6 and FVB/NJ (FVB) mice...
  48. pmc Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades
    Douglas Wahlsten
    Department of Psychology, University of Alberta, Edmonton, AB, Canada T6G 2E9
    Proc Natl Acad Sci U S A 103:16364-9. 2006
    ..Phenotypic drift over decades for most of the behaviors examined appears to be minimal...
  49. pmc The genomic determinants of alcohol preference in mice
    Boris Tabakoff
    Department of Pharmacology, University of Colorado Denver School of Medicine, Mail Stop F 8303, P O Box 6511, Aurora, CO 80045 0511, USA
    Mamm Genome 19:352-65. 2008
    ..The importance of olfactory cues, learning and memory formation (Pavlovian conditioning), and cortical executive function, for regulating alcohol intake by animals (including humans), is discussed...

Research Grants14

  1. NEUROSTEROID MODULATION OF ETHANOL WITHDRAWAL SEVERITY
    Deborah Finn; Fiscal Year: 2009
    ..This information will aid in our understanding of the mechanisms underlying alcohol withdrawal and will help in the development of new strategies for the treatment of alcohol dependence. ..
  2. NEUROSTEROID MODULATION OF ETHANOL WITHDRAWAL SEVERITY
    DEBORAH ANN FINN; Fiscal Year: 2010
    ..This information will aid in our understanding of the mechanisms underlying alcohol withdrawal and will help in the development of new strategies for the treatment of alcohol dependence. ..
  3. NEUROSTEROID MODULATION OF ETHANOL WITHDRAWAL SEVERITY
    Deborah Finn; Fiscal Year: 2007
    ..This information will aid in our understanding of the mechanisms underlying alcohol withdrawal and will help in the development of new strategies for the treatment of alcohol dependence. ..
  4. Excessive Alcohol Intake Induced By Withdrawal
    Deborah Finn; Fiscal Year: 2005
    ..Not only will this information help in furthering our understanding of the interaction between ethanol intake and withdrawal, but it also would aid in the development of new strategies for the treatment of alcoholism. ..
  5. NEUROSTEROID MODULATION OF ETHANOL WITHDRAWAL SEVERITY
    Deborah Finn; Fiscal Year: 2004
    ..Not only will this information aid in our understand of the mechanisms underlying alcohol withdrawal, but this knowledge would help in the development of new strategies for the treatment of alcohol dependence. ..
  6. Neurochemical Manipulation of Withdrawal-Induced Drinking
    DEBORAH ANN FINN; Fiscal Year: 2010
    ..Not only will this information help in furthering our understanding of the mechanisms underlying dependence-induced drinking, but it also will aid in the development of new strategies for the treatment of alcoholism. ..