Jonathan Emens

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. doi request reprint Circadian misalignment in major depressive disorder
    Jonathan Emens
    Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
    Psychiatry Res 168:259-61. 2009
  2. pmc Phase angle of entrainment in morning- and evening-types under naturalistic conditions
    Jonathan S Emens
    Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Chronobiol Int 26:474-93. 2009
  3. ncbi request reprint Circadian uses of melatonin in humans
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, Oregon 97239, USA
    Chronobiol Int 23:403-12. 2006
  4. ncbi request reprint Zeitgeber hierarchy in humans: resetting the circadian phase positions of blind people using melatonin
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
    Chronobiol Int 20:837-52. 2003
  5. pmc The phase shift hypothesis for the circadian component of winter depression
    Alfred J Lewy
    Oregon Health and Science University, Department of Psychiatry, Sleep and Mood Disorders Laboratory, Portland, Oregon, USA
    Dialogues Clin Neurosci 9:291-300. 2007
  6. ncbi request reprint Plasminogen activator inhibitor-1 has a circadian rhythm in blind individuals
    John A Schoenhard
    Thromb Haemost 98:479-81. 2007
  7. pmc The circadian basis of winter depression
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 103:7414-9. 2006
  8. ncbi request reprint Melatonin entrains free-running blind people according to a physiological dose-response curve
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Chronobiol Int 22:1093-106. 2005
  9. ncbi request reprint Relative coordination to unknown "weak zeitgebers" in free-running blind individuals
    Jonathan S Emens
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland 97239, USA
    J Biol Rhythms 20:159-67. 2005
  10. ncbi request reprint Eventual entrainment of the human circadian pacemaker by melatonin is independent of the circadian phase of treatment initiation: clinical implications
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
    J Biol Rhythms 19:68-75. 2004

Research Grants

Collaborators

Detail Information

Publications11

  1. doi request reprint Circadian misalignment in major depressive disorder
    Jonathan Emens
    Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
    Psychiatry Res 168:259-61. 2009
    ..We sought to determine if misalignment between the timing of sleep and the pacemaker correlated with symptom severity in MDD. Depression severity correlated with circadian misalignment: the more delayed, the more severe the symptoms...
  2. pmc Phase angle of entrainment in morning- and evening-types under naturalistic conditions
    Jonathan S Emens
    Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Chronobiol Int 26:474-93. 2009
    ..Specifically, evening types, compared to morning types, had a higher ratio of phase advancing to phase delaying by light. We interpret this as indicating a longer circadian period (tau) in evening types...
  3. ncbi request reprint Circadian uses of melatonin in humans
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, Oregon 97239, USA
    Chronobiol Int 23:403-12. 2006
    ....
  4. ncbi request reprint Zeitgeber hierarchy in humans: resetting the circadian phase positions of blind people using melatonin
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
    Chronobiol Int 20:837-52. 2003
    ....
  5. pmc The phase shift hypothesis for the circadian component of winter depression
    Alfred J Lewy
    Oregon Health and Science University, Department of Psychiatry, Sleep and Mood Disorders Laboratory, Portland, Oregon, USA
    Dialogues Clin Neurosci 9:291-300. 2007
    ....
  6. ncbi request reprint Plasminogen activator inhibitor-1 has a circadian rhythm in blind individuals
    John A Schoenhard
    Thromb Haemost 98:479-81. 2007
  7. pmc The circadian basis of winter depression
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 103:7414-9. 2006
    ..The findings support the phase-shift hypothesis for SAD, as well as suggest a way to assess the circadian component of other psychiatric, sleep, and chronobiologic disorders...
  8. ncbi request reprint Melatonin entrains free-running blind people according to a physiological dose-response curve
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Chronobiol Int 22:1093-106. 2005
    ..Left untreated, their free-running endocrine, metabolic, behavioral, and sleep/wake cycles can be almost as burdensome as not having vision...
  9. ncbi request reprint Relative coordination to unknown "weak zeitgebers" in free-running blind individuals
    Jonathan S Emens
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland 97239, USA
    J Biol Rhythms 20:159-67. 2005
    ..Sighted individuals may also be affected by such weak zeitgebers, which may be obscured by the stronger light/dark cycle...
  10. ncbi request reprint Eventual entrainment of the human circadian pacemaker by melatonin is independent of the circadian phase of treatment initiation: clinical implications
    Alfred J Lewy
    Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
    J Biol Rhythms 19:68-75. 2004
    ..Therefore, it is not essential that circadian phase be ascertained before starting low-dose melatonin treatment of blind people...
  11. ncbi request reprint Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period
    Alfred J Lewy
    Department of Psychiatry, Oregon Health and Science University, Portland, USA
    Chronobiol Int 19:649-58. 2002
    ..We now find that this person can be entrained to 0.5 mg of melatonin, but not to 20 mg. These results are consistent with the idea that too much melatonin may spill over onto the wrong zone of the melatonin phase-response curve...

Research Grants5

  1. Genetics of Morning/Evening Types in the Blind/Sighted
    Jonathan Emens; Fiscal Year: 2007
    ....