SIEGWARD M ELSAS

Summary

Affiliation: Oregon Health and Science University

Country: USA

Hippocampal zinc infusion delays the development of afterdischarges and seizures in a kindling model of epilepsy
SIEGWARD M ELSAS
Department of Neurology, University of California Los Angeles, Los Angeles, California, USA
Epilepsia 50:870-9. 2009
Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method
S M Elsas
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Phytomedicine 17:940-9. 2010

Hippocampal zinc infusion delays the development of afterdischarges and seizures in a kindling model of epilepsy
SIEGWARD M ELSAS
Department of Neurology, University of California Los Angeles, Los Angeles, California, USA
Epilepsia 50:870-9. 2009
..By blocking NMDA excitation or GABA inhibition, an excess of zinc may alter the excitability of hippocampal circuits, which contribute to the development of seizures...
Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method
S M Elsas
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Phytomedicine 17:940-9. 2010
..Instead of the anxiolytic effects described by others, anxiogenic effects in the elevated plus maze were seen in mice receiving any of the 5 Passiflora extracts...

Complementary treatment approach to epilepsy
Siegward Elsas; Fiscal Year: 2007
..At the end of the award period, Dr. Elsas will have completed a clinical trial of a botanical and will be well positioned to obtain independent research funding. ..