Victor A Derkach

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc Silence analysis of AMPA receptor mutated at the CaM-kinase II phosphorylation site
    Victor A Derkach
    Vollum Institute, Oregon Health Sciences University, Portland 97201, USA
    Biophys J 84:1701-8. 2003
  2. ncbi Regulatory mechanisms of AMPA receptors in synaptic plasticity
    Victor A Derkach
    Vollum Institute, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    Nat Rev Neurosci 8:101-13. 2007
  3. ncbi Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiation
    Michael C Oh
    Vollum Institute, Oregon Health and Sciences University, Portland, 97239, USA
    J Biol Chem 281:752-8. 2006
  4. pmc Recruitment of calcium-permeable AMPA receptors during synaptic potentiation is regulated by CaM-kinase I
    Eric S Guire
    Vollum Institute, Oregon Health and Sciences University, Portland, Oregon 97225, USA
    J Neurosci 28:6000-9. 2008
  5. pmc Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I
    Dale A Fortin
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosci 30:11565-75. 2010
  6. pmc Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors
    Dale A Fortin
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosci 32:8127-37. 2012
  7. ncbi Dominant role of the GluR2 subunit in regulation of AMPA receptors by CaMKII
    Michael C Oh
    Vollum Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    Nat Neurosci 8:853-4. 2005
  8. pmc High-resolution single-cell imaging for functional studies in the whole brain and spinal cord and thick tissue blocks using light-emitting diode illumination
    Boris V Safronov
    Instituto de Biologia Molecular e Celular IBMC, Universidade do Porto, Rua do Campo Alegre 823, 4150 180 Porto, Portugal
    J Neurosci Methods 164:292-8. 2007

Collaborators

Detail Information

Publications8

  1. pmc Silence analysis of AMPA receptor mutated at the CaM-kinase II phosphorylation site
    Victor A Derkach
    Vollum Institute, Oregon Health Sciences University, Portland 97201, USA
    Biophys J 84:1701-8. 2003
    ....
  2. ncbi Regulatory mechanisms of AMPA receptors in synaptic plasticity
    Victor A Derkach
    Vollum Institute, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    Nat Rev Neurosci 8:101-13. 2007
    ..These relationships offer new insights into the regulation of AMPARs and synaptic strength by cellular signalling...
  3. ncbi Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiation
    Michael C Oh
    Vollum Institute, Oregon Health and Sciences University, Portland, 97239, USA
    J Biol Chem 281:752-8. 2006
    ....
  4. pmc Recruitment of calcium-permeable AMPA receptors during synaptic potentiation is regulated by CaM-kinase I
    Eric S Guire
    Vollum Institute, Oregon Health and Sciences University, Portland, Oregon 97225, USA
    J Neurosci 28:6000-9. 2008
    ..Thus, synaptic expression of CP-AMPARs is a very efficient mechanism for rapid enhancement of synaptic strength that depends on CaMKK/CaMKI signaling, actin dynamics, and the pattern of synaptic activity used to induce CA1 LTP...
  5. pmc Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I
    Dale A Fortin
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosci 30:11565-75. 2010
    ..Together, our results suggest that synaptic recruitment of CP-AMPARs via CaMKI may provide a mechanistic link between NMDAR activation in LTP and regulation of a signaling pathway that drives spine enlargement via actin polymerization...
  6. pmc Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors
    Dale A Fortin
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosci 32:8127-37. 2012
    ..Together these data support the conclusion that newly synthesized GluA1 subunits, induced by BDNF, are readily incorporated into synapses where they enhance the expression of CP-AMPARs and synaptic strength...
  7. ncbi Dominant role of the GluR2 subunit in regulation of AMPA receptors by CaMKII
    Michael C Oh
    Vollum Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    Nat Neurosci 8:853-4. 2005
    ..Our findings define a previously unknown, dominant role of the GluR2 subunit in signaling mediated by CaMKII at AMPARs...
  8. pmc High-resolution single-cell imaging for functional studies in the whole brain and spinal cord and thick tissue blocks using light-emitting diode illumination
    Boris V Safronov
    Instituto de Biologia Molecular e Celular IBMC, Universidade do Porto, Rua do Campo Alegre 823, 4150 180 Porto, Portugal
    J Neurosci Methods 164:292-8. 2007
    ..The technique opens broad possibilities for a single-cell imaging and visually guided recordings from intact neuronal networks in the entire brain or spinal cord...