R H Dashwood

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. pmc Cancer chemopreventive mechanisms of tea against heterocyclic amine mutagens from cooked meat
    R H Dashwood
    The Linus Pauling Institute, and Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon 97331 6512
    Proc Soc Exp Biol Med 220:239-43. 1999
  2. pmc Inhibition by white tea of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced colonic aberrant crypts in the F344 rat
    G Santana-Rios
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Nutr Cancer 41:98-103. 2001
  3. ncbi request reprint beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol
    C A Blum
    Linus Pauling Institute and Department of Environment and Molecular Toxicology, Oregon State University, Corvallis, OR 97331 6512, USA
    Carcinogenesis 22:315-20. 2001
  4. ncbi request reprint Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz
    R H Dashwood
    Linus Pauling Institute, Oregon State University, Corvallis 97331 6512, USA
    Eur J Cancer Prev 10:139-45. 2001
  5. ncbi request reprint The disposition and metabolism of 2-amino-3-methylimidazo-[4,5-f]quinoline in the F344 rat at high versus low doses of indole-3-carbinol
    R H Dashwood
    Linus Pauling Institute, and Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331 6512, USA
    Food Chem Toxicol 41:1185-92. 2003
  6. pmc Bcl-2 overexpression in PhIP-induced colon tumors: cloning of the rat Bcl-2 promoter and characterization of a pathway involving beta-catenin, c-Myc and E2F1
    Q Li
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
    Oncogene 26:6194-202. 2007

Collaborators

  • M Xu
  • Q Li
  • G S Bailey
  • G A Orner
  • G Santana-Rios
  • C A Blum
  • D T Horio
  • M Izquierdo-Pulido
  • A T Fong
  • G D Stoner

Detail Information

Publications6

  1. pmc Cancer chemopreventive mechanisms of tea against heterocyclic amine mutagens from cooked meat
    R H Dashwood
    The Linus Pauling Institute, and Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon 97331 6512
    Proc Soc Exp Biol Med 220:239-43. 1999
    ..Collectively, the results indicate that tea possesses anticarcinogenic activity in the colon, and this most likely involves multiple inhibitory mechanisms...
  2. pmc Inhibition by white tea of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced colonic aberrant crypts in the F344 rat
    G Santana-Rios
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Nutr Cancer 41:98-103. 2001
    ....
  3. ncbi request reprint beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol
    C A Blum
    Linus Pauling Institute and Department of Environment and Molecular Toxicology, Oregon State University, Corvallis, OR 97331 6512, USA
    Carcinogenesis 22:315-20. 2001
    ....
  4. ncbi request reprint Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz
    R H Dashwood
    Linus Pauling Institute, Oregon State University, Corvallis 97331 6512, USA
    Eur J Cancer Prev 10:139-45. 2001
    ....
  5. ncbi request reprint The disposition and metabolism of 2-amino-3-methylimidazo-[4,5-f]quinoline in the F344 rat at high versus low doses of indole-3-carbinol
    R H Dashwood
    Linus Pauling Institute, and Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331 6512, USA
    Food Chem Toxicol 41:1185-92. 2003
    ..The possible significance of the low versus high dose effects are discussed in the context of ongoing clinical trials with I3C and the reported chemopreventive mechanisms in vivo...
  6. pmc Bcl-2 overexpression in PhIP-induced colon tumors: cloning of the rat Bcl-2 promoter and characterization of a pathway involving beta-catenin, c-Myc and E2F1
    Q Li
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
    Oncogene 26:6194-202. 2007
    ..These findings suggest an indirect pathway for Bcl-2 over-expression in PhIP-induced colon tumors involving beta-catenin, c-Myc and E2F1...