D M Cook
Affiliation: Oregon Health and Science University
- Route of estrogen administration helps to determine growth hormone (GH) replacement dose in GH-deficient adultsD M Cook
Oregon Health Sciences University, Portland 97201 3098, USA
J Clin Endocrinol Metab 84:3956-60. 1999..These observations may be useful in anticipating appropriate starting and final doses of GH in adult hypopituitary patients...
- A review of guidelines for use of growth hormone in pediatric and transition patientsDavid M Cook
Department of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, 3181 South West Sam Jackson Park Road, Suite 140, Portland, OR 97239, USA
Pituitary 15:301-10. 2012..Adherence to these guidelines will help to ensure that patients with disorders of growth failure or short stature receive the necessary therapy to increase linear growth and transition smoothly to healthy adulthood...
- Growth hormone dosing variables in growth hormone-deficient adultsDavid M Cook
Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201 3001, USA
Growth Horm IGF Res 16:S49-54. 2006..Based on this review, we offer practical recommendations for endocrinologists in the management of adults with hypopituitarism and long-term GH treatment...
- Long-term management of prolactinomas--use of long-acting dopamine agonistsDavid M Cook
Oregon Health and Sciences University, Endocrinology, L607, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
Rev Endocr Metab Disord 6:15-21. 2005
- Growth hormone and estrogen: a clinician's approachDavid M Cook
Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University Portland, OR 97239 3098, USA
J Pediatr Endocrinol Metab 17:1273-6. 2004..Clinical endocrinologists are in the best position to put all these variables into a successful therapeutic scenario...
- The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient adultsD M Cook
Department of Medicine, Oregon Health Sciences University, Portland, Oregon 97201, USA
J Clin Endocrinol Metab 87:4508-14. 2002..Estrogen-treated women required approximately twice the dose needed in men to produce comparable IGF-I concentrations...
- Shouldn't adults with growth hormone deficiency be offered growth hormone replacement therapy?David M Cook
Oregon Health and Science University, Portland, Oregon, USA
Ann Intern Med 137:197-201. 2002..This analysis should encourage reluctant practitioners to at least consider growth hormone replacement therapy for patients with definite growth hormone deficiency--that is, patients with symptomatic panhypopituitarism...
- Acromegaly: a review of current medical therapy and new drugs on the horizonMaria Fleseriu
Department of Neurological Surgery, Division of Endocrinology, Diabetes, and Clinical Nutrition, and Northwest Pituitary Center, Oregon Health and Science University, Portland, Oregon 97239, USA
Neurosurg Focus 29:E15. 2010..Because a surgical cure can be difficult to achieve, all patients, even those with what seems to be a clinically and biochemically inactive disease, should undergo long-term biochemical testing and pituitary MR imaging...
- Clinical review: Is lack of recombinant growth hormone (GH)-releasing hormone in the United States a setback or time to consider glucagon testing for adult GH deficiency?Kevin C J Yuen
Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
J Clin Endocrinol Metab 94:2702-7. 2009..In this article, we review the existing published data and consensus guidelines and provide recommendations for alternative stimulation tests to the GHRH-ARG test...
- Prevalence of GH and other anterior pituitary hormone deficiencies in adults with nonsecreting pituitary microadenomas and normal serum IGF-1 levelsKevin C J Yuen
Department of Endocrinology, Oregon Health and Science University, Portland, OR 97239 3098, USA
Clin Endocrinol (Oxf) 69:292-8. 2008..This study aims to evaluate the prevalence of GH and other anterior pituitary hormone deficiencies, and to determine whether microadenomas per se could be associated with reduced GH response rates to GHRH-arginine stimulation...
- Evaluation of the pituitary function with insulin tolerance (hypoglycaemia) testing: are there any differences using insulin lispro compared to regular insulin?Kevin C J Yuen
Department of Endocrinology, Oregon Health and Science University, Portland, Oreg 97239 3098 USA
Horm Res 69:233-9. 2008..There are scarce data using short-acting insulin analogs for ITTs. This pilot study compares the effects of insulin lispro (LPI) with regular insulin (RGI) during an ITT...
- Is further evaluation for growth hormone (GH) deficiency necessary in fibromyalgia patients with low serum insulin-like growth factor (IGF)-I levels?Kevin C J Yuen
Department of Endocrinology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Mailcode L607, Portland, OR 97239 3098, USA
Growth Horm IGF Res 17:82-8. 2007..The aim of this study was to assess the GH reserve in FM patients with low serum IGF-I levels using the GH-releasing hormone (GHRH)-arginine test...
- Effectiveness of self- or partner-administration of an extended-release aqueous-gel formulation of lanreotide in lanreotide-naïve patients with acromegalyRoberto Salvatori
Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Pituitary 13:115-22. 2010..0001). Self- or partner-administration of lanreotide is generally well tolerated and associated with IGF-1 and GH control in many lanreotide-naïve patients with acromegaly...
- Effect of growth hormone replacement on BMD in adult-onset growth hormone deficiencyPeter J Snyder
Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania, Philadelphia, PA 19104 6149, USA
J Bone Miner Res 22:762-70. 2007..To determine if replacement of GH improves BMD in adult-onset GHD, we administered GH in physiologic amounts to men and women with GHD. GH replacement significantly increased spine BMD in the men by 3.8%...
- Individual igf-I responsiveness to a fixed regimen of low-dose growth hormone replacement is increased with less variability in obese compared to non-obese adults with severe growth hormone deficiencyKevin C J Yuen
Department of Endocrinology, Addenbrooke s Hospital, Cambridge, UK, and Division of Endocrinology, Oregon Health and Science University, Portland 97239 3098, USA
Horm Res 65:6-13. 2006..To address this question, we challenged a cohort of severely GH-deficient non-obese and obese adults with a fixed low GH dose (0.2 mg/day), and examined the relationship of body mass index (BMI) with IGF-I response...
- Sensitivity and specificity of six tests for the diagnosis of adult GH deficiencyBeverly M K Biller
Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 87:2067-79. 2002..The ARG plus GHRH test represents an excellent alternative to the ITT for the diagnosis of GH deficiency in adults...
- Transition of childhood-onset growth hormone-deficient patients to adult healthcareRobert Rapaport
Division of Pediatric Endocrinology and Diabetes, Mount Sinai School of Medicine, New York, New York
Pediatr Endocrinol Rev 4:82-90. 2006..g. reduced bone mineral density) typically associated with interruption of GH treatment...