Daniel R Cleary
Affiliation: Oregon Health and Science University
- Neuropeptide Y in the rostral ventromedial medulla reverses inflammatory and nerve injury hyperalgesia in rats via non-selective excitation of local neuronsD R Cleary
Department of Neurological Surgery, Oregon Health and Science University, Portland, OR, United States Electronic address
Neuroscience 271:149-59. 2014..Although ON-cells undoubtedly facilitate nociception and contribute to hypersensitivity, the present results highlight the importance of parallel OFF-cell-mediated descending inhibition in limiting the expression of chronic pain. ..
- Adaptations in responsiveness of brainstem pain-modulating neurons in acute compared with chronic inflammationDaniel R Cleary
Department of Neurological Surgery, Oregon Health and Science University, Portland, OR, USA
Pain 154:845-55. 2013..The efficacy of OFF-cells in counteracting sensitization of ascending transmission pathways could therefore be an important determining factor in development of chronic inflammatory pain...
- Deep brain stimulation entrains local neuronal firing in human globus pallidus internusDaniel R Cleary
Neurological Surgery, MC L 472, Oregon Health and Science Univ, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
J Neurophysiol 109:978-87. 2013..These data indicate that DBS in the human GPi does not silence neuronal activity, but instead disrupts the pathological firing patterns through loose entrainment of neuronal activity...
- A novel, non-invasive method of respiratory monitoring for use with stereotactic proceduresDaniel R Cleary
Department of Neurological Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
J Neurosci Methods 209:337-43. 2012..This novel technique can therefore be used to measure respiratory rate and relative tidal volume when stereotaxic procedures are needed for neuronal manipulations and recording...
- Deep brain stimulation does not silence neurons in subthalamic nucleus in Parkinson's patientsJonathan D Carlson
Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon, USA
J Neurophysiol 103:962-7. 2010....
- Pain-facilitating medullary neurons contribute to opioid-induced respiratory depressionRyan S Phillips
Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
J Neurophysiol 108:2393-404. 2012..These findings show that pain relief can be separated pharmacologically from respiratory depression and identify RVM OFF-cells as important central targets for continued development of potent analgesics with fewer side effects...