S S Chugh

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Gadolinium-enhanced magnetic resonance imaging for detection and quantification of fibrosis in human myocardium in vitro
    Elizabeth Kehr
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, UHN 62, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Int J Cardiovasc Imaging 24:61-8. 2008
  2. pmc A community-based evaluation of sudden death associated with therapeutic levels of methadone
    Sumeet S Chugh
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland 97239, USA
    Am J Med 121:66-71. 2008
  3. ncbi request reprint Sudden cardiac death with apparently normal heart
    S S Chugh
    Jesse E Edwards Registry of Cardiovascular Disease, United Hospital, St Paul, MN, USA
    Circulation 102:649-54. 2000
  4. ncbi request reprint Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large U.S. community
    Sumeet S Chugh
    Heart Rhythm Research Laboratory, Division of Cardiology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Am Coll Cardiol 44:1268-75. 2004
  5. ncbi request reprint Postmortem molecular screening in unexplained sudden death
    Sumeet S Chugh
    Division of Cardiology, Oregon Health and Science University, Portland, 97239, USA
    J Am Coll Cardiol 43:1625-9. 2004
  6. ncbi request reprint Cardiac pathologic findings reveal a high rate of sudden cardiac death of undetermined etiology in younger women
    Sumeet S Chugh
    Division of Cardiology, Oregon Health and Science University, Portland, Ore 97239, USA
    Am Heart J 146:635-9. 2003
  7. pmc Epidemiology of sudden cardiac death: clinical and research implications
    Sumeet S Chugh
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Prog Cardiovasc Dis 51:213-28. 2008
  8. ncbi request reprint Genetic basis for chamber-specific ventricular phenotypes in the rat infarct model
    Sumeet S Chugh
    Division of Cardiology, Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Cardiovasc Res 57:477-85. 2003
  9. ncbi request reprint Amplified effects of d,l-sotalol in canine dilated cardiomyopathy
    S S Chugh
    Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
    Pacing Clin Electrophysiol 24:1783-8. 2001
  10. ncbi request reprint Altered response to ibutilide in a heart failure model
    S S Chugh
    Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Cardiovasc Res 49:94-102. 2001

Research Grants

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Gadolinium-enhanced magnetic resonance imaging for detection and quantification of fibrosis in human myocardium in vitro
    Elizabeth Kehr
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, UHN 62, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Int J Cardiovasc Imaging 24:61-8. 2008
    ....
  2. pmc A community-based evaluation of sudden death associated with therapeutic levels of methadone
    Sumeet S Chugh
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland 97239, USA
    Am J Med 121:66-71. 2008
    ..Because of the established utility of this drug and with the eventual goal of enhancing safety of use, we performed a community-based study to evaluate this association...
  3. ncbi request reprint Sudden cardiac death with apparently normal heart
    S S Chugh
    Jesse E Edwards Registry of Cardiovascular Disease, United Hospital, St Paul, MN, USA
    Circulation 102:649-54. 2000
    ..Large autopsy series may provide a unique opportunity to confirm structural normalcy of the heart before reviewing a patient's clinical history...
  4. ncbi request reprint Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large U.S. community
    Sumeet S Chugh
    Heart Rhythm Research Laboratory, Division of Cardiology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Am Coll Cardiol 44:1268-75. 2004
    ..To assess the validity of retrospective surveillance, a simultaneous comparison was made with a death certificate-based method of determining SCD incidence...
  5. ncbi request reprint Postmortem molecular screening in unexplained sudden death
    Sumeet S Chugh
    Division of Cardiology, Oregon Health and Science University, Portland, 97239, USA
    J Am Coll Cardiol 43:1625-9. 2004
    ..We examined the prevalence of defects in arrhythmia-related candidate genes among patients with unexplained sudden cardiac death (SCD)...
  6. ncbi request reprint Cardiac pathologic findings reveal a high rate of sudden cardiac death of undetermined etiology in younger women
    Sumeet S Chugh
    Division of Cardiology, Oregon Health and Science University, Portland, Ore 97239, USA
    Am Heart J 146:635-9. 2003
    ..In contrast, the sudden cardiac death rate in age-matched men showed a decreasing trend (-2.8%). Due to under-representation of younger adults in published autopsy series, etiologies of sudden cardiac death merit further investigation...
  7. pmc Epidemiology of sudden cardiac death: clinical and research implications
    Sumeet S Chugh
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Prog Cardiovasc Dis 51:213-28. 2008
    ....
  8. ncbi request reprint Genetic basis for chamber-specific ventricular phenotypes in the rat infarct model
    Sumeet S Chugh
    Division of Cardiology, Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Cardiovasc Res 57:477-85. 2003
    ..The existence of this and other such distinct electrophysiologic phenotypes in right (RV) vs. left ventricles (LV) could be explained by chamber-specific patterns of gene expression...
  9. ncbi request reprint Amplified effects of d,l-sotalol in canine dilated cardiomyopathy
    S S Chugh
    Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
    Pacing Clin Electrophysiol 24:1783-8. 2001
    ..While using d,l-sotalol in heart failure, independent additional effects due to ventricular electrical remodeling may be a consideration...
  10. ncbi request reprint Altered response to ibutilide in a heart failure model
    S S Chugh
    Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Cardiovasc Res 49:94-102. 2001
    ..Despite the frequent use of anti-arrhythmic drugs in the general population, the electrophysiologic effects of these agents have not been elucidated in congestive heart failure (CHF)...
  11. pmc Quantification of diffuse myocardial fibrosis and its association with myocardial dysfunction in congenital heart disease
    Craig S Broberg
    Adult Congenital Heart Disease Program, Oregon Health and Science University, Portland, Ore, USA
    Circ Cardiovasc Imaging 3:727-34. 2010
    ..the etiology of ventricular dysfunction in adult congenital heart disease (ACHD) is not well understood. Diffuse fibrosis is a likely common final pathway and is quantifiable using MRI...
  12. ncbi request reprint Global remodeling of the ventricular interstitium in idiopathic myocardial fibrosis and sudden cardiac death
    Benjamin T John
    Division of Cardiology, Oregon Health and Science University, Portland, Oregon, USA
    Heart Rhythm 1:141-9. 2004
    ..Characterization of a distinct, and as yet unexplained phenotype of sudden cardiac death (SCD)...
  13. pmc Independent contribution of diabetes to increased prevalence and incidence of atrial fibrillation
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 32:1851-6. 2009
    ..We sought to compare the prevalence and incidence of atrial fibrillation in age- and sex-matched patients with and without type 2 diabetes...
  14. pmc Determinants of prolonged QT interval and their contribution to sudden death risk in coronary artery disease: the Oregon Sudden Unexpected Death Study
    Sumeet S Chugh
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, USA
    Circulation 119:663-70. 2009
    ..We evaluated determinants of prolonged QTc and the relationship of prolonged QTc to SCD risk among patients with coronary artery disease in the general population...
  15. pmc Physical activity as a trigger of sudden cardiac arrest: the Oregon Sudden Unexpected Death Study
    Pulla R Reddy
    Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon 97239, United States
    Int J Cardiol 131:345-9. 2009
    ..Vigorous physical activity has been suggested as a prominent trigger but has not been well-evaluated in the general population. We performed a community-based study to analyze the role of physical activity as a potential trigger of SCA...
  16. ncbi request reprint Early changes in gene expression that influence the course of primary glomerular disease
    L C Clement
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Kidney Int 72:337-47. 2007
    ..Our studies suggest that an early and persistent change in mostly steroid-resistant glomerular gene expression is the hallmark of severe and progressive glomerular disease...
  17. ncbi request reprint Incidence of sudden cardiac arrest is higher in areas of low socioeconomic status: a prospective two year study in a large United States community
    Kyndaron Reinier
    Heart Rhythm Research Laboratory, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Resuscitation 70:186-92. 2006
    ..A potential effect of socioeconomic status on occurrence of sudden cardiac arrest in the community is likely, but has not been evaluated fully...
  18. ncbi request reprint Arrhythmias after orthotopic heart transplantation
    Eric C Stecker
    Department of Cardiology, Oregon Health and Science University, Portland, 97201, USA
    J Card Fail 11:464-72. 2005
    ..Arrhythmias frequently occur after orthotopic heart transplantation (OHT)...
  19. ncbi request reprint Nonautomatic focal atrial tachycardia: characterization and ablation of a poorly understood arrhythmia in 38 patients
    Janneke A E Kammeraad
    Department of Pediatrics, Division of Cardiology, Oregon Health and Science University, 707 SW Gaines Road, Portland, OR 97201, USA
    Pacing Clin Electrophysiol 26:736-42. 2003
    ..In conclusion, NAFAT is a rare arrhythmia which predominantly affects women with no other associated cardiac disease. It mainly occurs in the right atrium, affects all ages and is amenable to catheter ablation...
  20. ncbi request reprint Apparent protective effect of increased left ventricular wall thickness in an ICD population
    Vivek Dogra
    Division of Cardiology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    J Card Fail 9:412-5. 2003
    ..Because a subgroup of patients who receive ICDs may not receive therapies, we sought to identify clinical predictors of therapy-free survival in ICD patients...
  21. ncbi request reprint Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death Study
    Eric C Stecker
    Heart Rhythm Research Laboratory, Division of Cardiology, Oregon Health and Science University, Portland, Oregon
    J Am Coll Cardiol 47:1161-6. 2006
    ..We sought to evaluate the contribution of left ventricular (LV) dysfunction toward occurrence of sudden cardiac death (SCD) in the general population, and to identify distinguishing characteristics of SCD in the absence of LV dysfunction...
  22. ncbi request reprint Native QRS duration predicts the occurrence of arrhythmic events in ICD recipients
    Eric C Stecker
    Heart Rhythm Research Laboratory, Division of Cardiology, UHN 62, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Europace 8:859-62. 2006
    ..Native QRS duration is an established predictor of overall mortality, but the role of this parameter as a clinical predictor of arrhythmic events warrants further investigation...
  23. ncbi request reprint Genomics in sudden cardiac death
    Dan E Arking
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Room 580, Baltimore, MD 21205, USA
    Circ Res 94:712-23. 2004
    ..The development of novel strategies to identify contributors to susceptibility in common cardiac phenotypes is most likely to lead to new and relevant therapeutic targets for SCD...
  24. ncbi request reprint Confronting the genetic complexity of atrial fibrillation: this too shall pass
    Sumeet S Chugh
    Heart Rhythm 4:476-7. 2007
  25. ncbi request reprint Learning from a real-world analysis of implantable cardioverter-defibrillator recipients: comorbidities matter
    Sumeet S Chugh
    J Am Coll Cardiol 49:2416-8. 2007

Research Grants2

  1. Determinants of Sudden Death Risk with Left Ventricular Hypertrophy
    Sumeet Chugh; Fiscal Year: 2007
    ..A postmortem, case control approach will be used to compare LV myocardial interstitial remodeling in a subgroup of SCD cases with isolated LVH, vs. controls with isolated LVH, vs. normal controls. ..