Sean M Bugel

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. doi request reprint Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium
    Sean M Bugel
    Department of Environmental and Molecular Toxicology, Environmental Health Sciences Center, Sinnhuber Aquatic Research Laboratory, Oregon State University, Corvallis, OR 97331, United States Electronic address
    Toxicol Appl Pharmacol 296:31-41. 2016
  2. pmc Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes
    Sean M Bugel
    Department of Environmental and Molecular Toxicology, Environmental Health Sciences Center, Oregon State University, Corvallis, OR 97331, United States Electronic address
    Aquat Toxicol 152:222-31. 2014
  3. doi request reprint Inhibition of vitellogenin gene induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio)
    Sean M Bugel
    Department of Environmental Sciences, Rutgers, The State University of New Jersey, New Brunswick, 08901, United States
    Aquat Toxicol 126:1-8. 2013
  4. doi request reprint Decreased vitellogenin inducibility and 17β-estradiol levels correlated with reduced egg production in killifish (Fundulus heteroclitus) from Newark Bay, NJ
    Sean M Bugel
    Rutgers, The State University of New Jersey, Department of Environmental Sciences, United States
    Aquat Toxicol 105:1-12. 2011
  5. doi request reprint Impaired reproductive health of killifish (Fundulus heteroclitus) inhabiting Newark Bay, NJ, a chronically contaminated estuary
    Sean M Bugel
    Rutgers, The State University of New Jersey, Department of Environmental Sciences, United States
    Aquat Toxicol 96:182-93. 2010

Detail Information

Publications5

  1. doi request reprint Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium
    Sean M Bugel
    Department of Environmental and Molecular Toxicology, Environmental Health Sciences Center, Sinnhuber Aquatic Research Laboratory, Oregon State University, Corvallis, OR 97331, United States Electronic address
    Toxicol Appl Pharmacol 296:31-41. 2016
    ..These studies help advance our understanding of tamoxifen's non-classical mode of action and implicate a possible role for MMPs in tissues such as skin. ..
  2. pmc Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes
    Sean M Bugel
    Department of Environmental and Molecular Toxicology, Environmental Health Sciences Center, Oregon State University, Corvallis, OR 97331, United States Electronic address
    Aquat Toxicol 152:222-31. 2014
    ....
  3. doi request reprint Inhibition of vitellogenin gene induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio)
    Sean M Bugel
    Department of Environmental Sciences, Rutgers, The State University of New Jersey, New Brunswick, 08901, United States
    Aquat Toxicol 126:1-8. 2013
    ..This work provides evidence for AHR2 dependent cross-talk inhibition of vitellogenin genes and offers insight into anti-estrogenic reproductive effects observed in oviparous species exposed to AHR agonist contaminants...
  4. doi request reprint Decreased vitellogenin inducibility and 17β-estradiol levels correlated with reduced egg production in killifish (Fundulus heteroclitus) from Newark Bay, NJ
    Sean M Bugel
    Rutgers, The State University of New Jersey, Department of Environmental Sciences, United States
    Aquat Toxicol 105:1-12. 2011
    ..These studies demonstrate that contaminants within Newark Bay exert both estrogenic and anti-estrogenic responses which results in an overtly anti-estrogenic phenotype (reduced egg production due to inhibition of vitellogenesis)...
  5. doi request reprint Impaired reproductive health of killifish (Fundulus heteroclitus) inhabiting Newark Bay, NJ, a chronically contaminated estuary
    Sean M Bugel
    Rutgers, The State University of New Jersey, Department of Environmental Sciences, United States
    Aquat Toxicol 96:182-93. 2010
    ..Similar effects on the reproductive development in less resilient species may limit their ability to repopulate the NY-NJ Harbor Estuary and similarly contaminated water systems...