Thimmappa S Anekonda

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Can herbs provide a new generation of drugs for treating Alzheimer's disease?
    Thimmappa S Anekonda
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res Brain Res Rev 50:361-76. 2005
  2. ncbi request reprint Resveratrol--a boon for treating Alzheimer's disease?
    Thimmappa S Anekonda
    Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, 97006, USA
    Brain Res Rev 52:316-26. 2006
  3. pmc Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70
    Thimmappa S Anekonda
    Department of Ophthalmology, Casey Eye Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA
    BMC Res Notes 1:122. 2008
  4. pmc L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Neurobiol Dis 41:62-70. 2011
  5. pmc Phytic acid as a potential treatment for alzheimer's pathology: evidence from animal and in vitro models
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    J Alzheimers Dis 23:21-35. 2011
  6. pmc Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR, USA
    Biochim Biophys Acta 1812:1584-90. 2011
  7. pmc A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug
    Philip F Copenhaver
    Department of Cell and Developmental Biology, Oregon Health andScience University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Dis Model Mech 4:634-48. 2011
  8. ncbi request reprint Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
    Maria Manczak
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Aveue, Beaverton, 97006, USA
    Hum Mol Genet 15:1437-49. 2006
  9. ncbi request reprint Neuronal protection by sirtuins in Alzheimer's disease
    Thimmappa S Anekonda
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    J Neurochem 96:305-13. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Can herbs provide a new generation of drugs for treating Alzheimer's disease?
    Thimmappa S Anekonda
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res Brain Res Rev 50:361-76. 2005
    ..The chemical compositions of herbs and their potential for alleviating or reducing symptoms of AD or for affecting the disease mechanism need to be further studied...
  2. ncbi request reprint Resveratrol--a boon for treating Alzheimer's disease?
    Thimmappa S Anekonda
    Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, 97006, USA
    Brain Res Rev 52:316-26. 2006
    ..This paper mainly focuses on the role of resveratrol in modulating AD pathomechanisms...
  3. pmc Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70
    Thimmappa S Anekonda
    Department of Ophthalmology, Casey Eye Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA
    BMC Res Notes 1:122. 2008
    ..To determine whether resveratrol, a natural plant-derived drug, has protective effects against antibody-induced apoptosis of retinal cells in vitro and to provide insights on the mechanism of resveratrol protection...
  4. pmc L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Neurobiol Dis 41:62-70. 2011
    ....
  5. pmc Phytic acid as a potential treatment for alzheimer's pathology: evidence from animal and in vitro models
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    J Alzheimers Dis 23:21-35. 2011
    ..These results suggest that phytic acid may provide a viable treatment option for AD...
  6. pmc Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine
    Thimmappa S Anekonda
    Department of Neurology, Oregon Health and Science University, Portland, OR, USA
    Biochim Biophys Acta 1812:1584-90. 2011
    ..This review highlights the importance of Ca(v)1.2 channel overexpression, the accumulation of hyperphosphorylated tau and suppression of autophagy in Alzheimer's disease and modulation of this pathway by isradipine...
  7. pmc A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug
    Philip F Copenhaver
    Department of Cell and Developmental Biology, Oregon Health andScience University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Dis Model Mech 4:634-48. 2011
    ....
  8. ncbi request reprint Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
    Maria Manczak
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Aveue, Beaverton, 97006, USA
    Hum Mol Genet 15:1437-49. 2006
    ..These findings suggest that early mitochondrially targeted therapeutic interventions may be effective in delaying AD progression in elderly individuals and in treating AD patients...
  9. ncbi request reprint Neuronal protection by sirtuins in Alzheimer's disease
    Thimmappa S Anekonda
    Neurogenetics Laboratory, Neurological Sciences Institute, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    J Neurochem 96:305-13. 2006
    ..In this review, we discuss the possible mechanisms of sirtuins involved in neuronal protection and the potential therapeutic value of sirtuins in healthy aging and AD...