Arnab Basu

Summary

Affiliation: One Innovation Drive
Country: USA

Publications

  1. ncbi Identification of a small-molecule entry inhibitor for filoviruses
    Arnab Basu
    Microbiotix, Inc, One Innovation Drive, Worcester, MA 01605, USA
    J Virol 85:3106-19. 2011
  2. ncbi High-throughput screening of viral entry inhibitors using pseudotyped virus
    Arnab Basu
    Microbiotix, Worcester, Massachusetts, USA
    Curr Protoc Pharmacol . 2010

Research Grants

  1. Identification of HCV E1 an E2 Inhibitors
    Arnab Basu; Fiscal Year: 2006
  2. Identification of Ebola Virus Entry Inhibitors
    Arnab Basu; Fiscal Year: 2007
  3. Developing small molecule therapeutics for Ebola hemorrhagic fever virus
    Arnab Basu; Fiscal Year: 2010

Detail Information

Publications2

  1. ncbi Identification of a small-molecule entry inhibitor for filoviruses
    Arnab Basu
    Microbiotix, Inc, One Innovation Drive, Worcester, MA 01605, USA
    J Virol 85:3106-19. 2011
    ..In summary, we have identified a novel series of benzodiazepine compounds that are suitable for optimization as potential inhibitors of filoviral infection...
  2. ncbi High-throughput screening of viral entry inhibitors using pseudotyped virus
    Arnab Basu
    Microbiotix, Worcester, Massachusetts, USA
    Curr Protoc Pharmacol . 2010
    ..This unit includes protocols for preparing pseudotyped viruses using lentiviral vectors and use of pseudotyped viruses for high-throughput screening of viral entry inhibitors...

Research Grants4

  1. Identification of HCV E1 an E2 Inhibitors
    Arnab Basu; Fiscal Year: 2006
    ..The most promising compound will advance to IND-enabling toxicology and pharmacology studies in two species (Phase III). ..
  2. Identification of Ebola Virus Entry Inhibitors
    Arnab Basu; Fiscal Year: 2007
    ..EBOV inhibitor confirmation; and 4. Prioritize screening hits based on spectrum, cytotoxicity and mechanism. The end result of Phase 1 work will be identification of hits specific for EBOV entry inhibition. ..
  3. Developing small molecule therapeutics for Ebola hemorrhagic fever virus
    Arnab Basu; Fiscal Year: 2010
    ..Identify EBOV inhibitors with in vitro ADME properties suitable for i.v. and oral dosing;and 5. Evaluate EBOV inhibitors in a guinea pig model of EBOV infection. ..