Shu Xiao

Summary

Affiliation: Old Dominion University
Country: USA

Publications

  1. doi request reprint Subnanosecond electric pulses cause membrane permeabilization and cell death
    Shu Xiao
    Frank Reidy Research Center for Bioelectrics, Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, VA 23529, USA
    IEEE Trans Biomed Eng 58:1239-45. 2011
  2. pmc Recruitment of the intracellular Ca2+ by ultrashort electric stimuli: the impact of pulse duration
    Iurii Semenov
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Cell Calcium 54:145-50. 2013
  3. pmc Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media
    Olga N Pakhomova
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Arch Biochem Biophys 527:55-64. 2012
  4. pmc Electroporation-induced electrosensitization
    Olga N Pakhomova
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia, United States of America
    PLoS ONE 6:e17100. 2011
  5. pmc Transient features in nanosecond pulsed electric fields differentially modulate mitochondria and viability
    Stephen J Beebe
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia, United States of America
    PLoS ONE 7:e51349. 2012
  6. pmc Primary pathways of intracellular Ca(2+) mobilization by nanosecond pulsed electric field
    Iurii Semenov
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Biochim Biophys Acta 1828:981-9. 2013
  7. doi request reprint Nanosecond pulse electric field (nanopulse): a novel non-ligand agonist for platelet activation
    Jue Zhang
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Arch Biochem Biophys 471:240-8. 2008
  8. pmc Cell permeabilization and inhibition of voltage-gated Ca(2+) and Na(+) channel currents by nanosecond pulsed electric field
    Vasyl Nesin
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Bioelectromagnetics 33:394-404. 2012
  9. pmc Manipulation of cell volume and membrane pore comparison following single cell permeabilization with 60- and 600-ns electric pulses
    Olena M Nesin
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Biochim Biophys Acta 1808:792-801. 2011
  10. ncbi request reprint Model study of time-dependent muscle response to pulsed electrical stimulation
    Ravindra P Joshi
    Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, Virginia, USA
    Bioelectromagnetics 31:361-70. 2010

Collaborators

Detail Information

Publications12

  1. doi request reprint Subnanosecond electric pulses cause membrane permeabilization and cell death
    Shu Xiao
    Frank Reidy Research Center for Bioelectrics, Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, VA 23529, USA
    IEEE Trans Biomed Eng 58:1239-45. 2011
    ..This means that the cell membrane behaves like a rectifying diode. This increase in membrane conductance is a nonthermal process, since the temperature rise due to the pulsing is negligible...
  2. pmc Recruitment of the intracellular Ca2+ by ultrashort electric stimuli: the impact of pulse duration
    Iurii Semenov
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Cell Calcium 54:145-50. 2013
    ..We conclude that nanosecond stimuli mimic Ca2+ signaling while bypassing the usual receptor- and channels-mediated cascades. The recruitment of the intracellular Ca2+ can be controlled by the duration of the stimulus...
  3. pmc Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media
    Olga N Pakhomova
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Arch Biochem Biophys 527:55-64. 2012
    ..Therefore, bioeffects of nsPEF are not limited to electropermeabilization; concurrent ROS formation may lead to cell stimulation and/or oxidative cell damage...
  4. pmc Electroporation-induced electrosensitization
    Olga N Pakhomova
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia, United States of America
    PLoS ONE 6:e17100. 2011
    ..No studies have accounted for the biological consequences of electroporation as a factor that alters the cell's susceptibility to forthcoming EPs...
  5. pmc Transient features in nanosecond pulsed electric fields differentially modulate mitochondria and viability
    Stephen J Beebe
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia, United States of America
    PLoS ONE 7:e51349. 2012
    ....
  6. pmc Primary pathways of intracellular Ca(2+) mobilization by nanosecond pulsed electric field
    Iurii Semenov
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Biochim Biophys Acta 1828:981-9. 2013
    ..NsPEF stimulation may serve as a unique method to mobilize [Ca(2+)](i) and activate downstream cascades while bypassing the plasma membrane receptors...
  7. doi request reprint Nanosecond pulse electric field (nanopulse): a novel non-ligand agonist for platelet activation
    Jue Zhang
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Arch Biochem Biophys 471:240-8. 2008
    ..We conclude that nsPEFs dose-dependently cause platelets to rapidly aggregate, like other platelet agonists, and this is most likely initiated by the nsPEFs increasing [Ca2+]i, however by a different mechanism...
  8. pmc Cell permeabilization and inhibition of voltage-gated Ca(2+) and Na(+) channel currents by nanosecond pulsed electric field
    Vasyl Nesin
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA
    Bioelectromagnetics 33:394-404. 2012
    ..The causal relation of nsPEF inhibitory effects on VG currents and permeabilization of the plasma membrane is discussed...
  9. pmc Manipulation of cell volume and membrane pore comparison following single cell permeabilization with 60- and 600-ns electric pulses
    Olena M Nesin
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA
    Biochim Biophys Acta 1808:792-801. 2011
    ..For both the 60- and 600-ns exposures, cell volume changes were determined by pores smaller than 0.9 nm in diameter; however, the diameter increased with increasing the nsEP intensity...
  10. ncbi request reprint Model study of time-dependent muscle response to pulsed electrical stimulation
    Ravindra P Joshi
    Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, Virginia, USA
    Bioelectromagnetics 31:361-70. 2010
    ..Other possibilities such as calcium release at nerve end endings also exist. It is also proposed that multipulsing strategies and changing the electric field direction by using multielectrode systems would be useful...
  11. ncbi request reprint Long-lasting plasma membrane permeabilization in mammalian cells by nanosecond pulsed electric field (nsPEF)
    Andrei G Pakhomov
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, Virginia, USA
    Bioelectromagnetics 28:655-63. 2007
    ..The phenomenon of long-lived membrane permeabilization provides new insights on the nature of nsPEF-opened conductance pores and on molecular mechanisms that underlie nsPEF bioeffects...
  12. doi request reprint Scaling of surface-plasma reactors with a significantly increased energy density for NO conversion
    Muhammad Arif Malik
    Frank Reidy Research Center for Bioelectrics, Old Dominion University, 4211 Monarch Way, Suite 300, Norfolk, VA 23508, USA
    J Hazard Mater 209:293-8. 2012
    ..02 L/J in both the shielded and unshielded cases...