Affiliation: Old Dominion University
Neelakanta G, Sultana H, Sonenshine D, Marconi R. An In Vitro Blood-Feeding Method Revealed Differential Borrelia turicatae (Spirochaetales: Spirochaetaceae) Gene Expression After Spirochete Acquisition and Colonization in the Soft Tick Ornithodoros turicata (Acari: Argasidae). J Med Entomol. 2017;54:441-449 pubmed publisher
..We also report that B. turicatae genes are differentially expressed in ticks in comparison with the in vitro-grown cultures, indicating influence of tick environment on spirochete gene expression. ..
Taank V, Zhou W, Zhuang X, Anderson J, Pal U, Sultana H, et al
. Characterization of tick organic anion transporting polypeptides (OATPs) upon bacterial and viral infections. Parasit Vectors. 2018;11:593 pubmed publisher
..This study provides additional evidence on the role of arthropod OATPs in vector-intracellular pathogen interactions. ..
Neelakanta G, Sultana H. Transmission-Blocking Vaccines: Focus on Anti-Vector Vaccines against Tick-Borne Diseases. Arch Immunol Ther Exp (Warsz). 2015;63:169-79 pubmed publisher
Sultana H, Patel U, Sonenshine D, Neelakanta G. Identification and comparative analysis of subolesin/akirin ortholog from Ornithodoros turicata ticks. Parasit Vectors. 2015;8:132 pubmed publisher
Khanal S, Taank V, Anderson J, Sultana H, Neelakanta G. Arthropod transcriptional activator protein-1 (AP-1) aids tick-rickettsial pathogen survival in the cold. Sci Rep. 2018;8:11409 pubmed publisher
..phagocytophilum survival in the vector. In summary, our study defines a novel mode of arthropod signaling for the survival of both rickettsial pathogen and its medically important vector in the cold. ..
Sultana H, Patel U, Toliver M, Maggi R, Neelakanta G. Molecular identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15-kDa salivary gland protein (Salp15), from Ixodes affinis ticks. Ticks Tick Borne Dis. 2016;7:46-53 pubmed publisher
..affinis blood feeding and vector-pathogen interactions but may also lead to the development of an anti-vector vaccine against this group of ticks. ..
Neelakanta G, Sultana H. Viral receptors of the gut: vector-borne viruses of medical importance. Curr Opin Insect Sci. 2016;16:44-50 pubmed publisher
Taank V, Dutta S, Dasgupta A, Steeves T, Fish D, Anderson J, et al
. Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticks. Sci Rep. 2017;7:13256 pubmed publisher
..Collectively, this study provides important novel information in understanding the interplay between molecular pathways manipulated by a rickettsial pathogen to survive in its arthropod vector. ..