Sandra E Gomez-Mejiba

Summary

Affiliation: Oklahoma Medical Research Foundation
Country: USA

Publications

  1. pmc Myeloperoxidase-induced genomic DNA-centered radicals
    Sandra E Gomez-Mejiba
    Experimental Therapeutics Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
    J Biol Chem 285:20062-71. 2010
  2. doi request reprint In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 63:351-60. 2013
  3. pmc Immuno-spin trapping of protein and DNA radicals: "tagging" free radicals to locate and understand the redox process
    Sandra E Gomez-Mejiba
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 46:853-65. 2009
  4. pmc In vivo imaging of immuno-spin trapped radicals with molecular magnetic resonance imaging in a diabetic mouse model
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA
    Diabetes 61:2405-13. 2012
  5. pmc Cu,Zn-superoxide dismutase-driven free radical modifications: copper- and carbonate radical anion-initiated protein radical chemistry
    Dario C Ramirez
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Biochem J 417:341-53. 2009
  6. pmc Inhalation of environmental stressors & chronic inflammation: autoimmunity and neurodegeneration
    Sandra E Gomez-Mejiba
    Free Radical Biology and Aging Research Program, MS 21, 825 NE 13th Street, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, United States
    Mutat Res 674:62-72. 2009
  7. doi request reprint The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells
    Zili Zhai
    Experimental Therapeutics Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Life Sci 90:432-9. 2012
  8. doi request reprint In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA Electronic address
    Free Radic Biol Med 65:828-37. 2013

Detail Information

Publications8

  1. pmc Myeloperoxidase-induced genomic DNA-centered radicals
    Sandra E Gomez-Mejiba
    Experimental Therapeutics Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
    J Biol Chem 285:20062-71. 2010
    ..Taken together our results indicate that the formation of DNA-centered radicals by intracellular MPO may be a useful point of therapeutic intervention in inflammation-induced carcinogenesis...
  2. doi request reprint In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 63:351-60. 2013
    ..This novel, noninvasive, in vivo diagnostic method can be applied to investigate the involvement of free radical mechanisms in ALS rodent models...
  3. pmc Immuno-spin trapping of protein and DNA radicals: "tagging" free radicals to locate and understand the redox process
    Sandra E Gomez-Mejiba
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 46:853-65. 2009
    ....
  4. pmc In vivo imaging of immuno-spin trapped radicals with molecular magnetic resonance imaging in a diabetic mouse model
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA
    Diabetes 61:2405-13. 2012
    ..This method can be specifically applied toward diabetes models for in vivo assessment of free radical levels, providing an avenue to more fully understand the role of free radicals in diabetes...
  5. pmc Cu,Zn-superoxide dismutase-driven free radical modifications: copper- and carbonate radical anion-initiated protein radical chemistry
    Dario C Ramirez
    Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Biochem J 417:341-53. 2009
    ....
  6. pmc Inhalation of environmental stressors & chronic inflammation: autoimmunity and neurodegeneration
    Sandra E Gomez-Mejiba
    Free Radical Biology and Aging Research Program, MS 21, 825 NE 13th Street, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, United States
    Mutat Res 674:62-72. 2009
    ....
  7. doi request reprint The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells
    Zili Zhai
    Experimental Therapeutics Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Life Sci 90:432-9. 2012
    ..In this study, we sought to establish the anti-inflammatory activity of DMPO, presumably by removing free radicals which otherwise help activate inflammatory response and damage cells...
  8. doi request reprint In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA Electronic address
    Free Radic Biol Med 65:828-37. 2013
    ..05 for both), were elevated in septic brains compared to shams. This is the first study that has reported on the detection of in vivo and in situ levels of free radicals in murine septic encephalopathy. ..