Jose De La Fuente

Summary

Affiliation: Oklahoma State University
Country: USA

Publications

  1. pmc Fine-tuning the space, time, and host distribution of mycobacteria in wildlife
    Christian Gortazar
    IREC National Wildlife Research Institute CSIC UCLM JCCM, Ciudad Real, Spain
    BMC Microbiol 11:27. 2011
  2. pmc Allopatric speciation in ticks: genetic and reproductive divergence between geographic strains of Rhipicephalus (Boophilus) microplus
    Marcelo B Labruna
    Departamento de Medicina Veterinaria Preventiva e Saude Animal, Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    BMC Evol Biol 9:46. 2009
  3. pmc Vaccination with recombinant Boophilus annulatus Bm86 ortholog protein, Ba86, protects cattle against B. annulatus and B. microplus infestations
    Mario Canales
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, Ciudad Real, Spain
    BMC Biotechnol 9:29. 2009
  4. pmc Expression of recombinant Rhipicephalus (Boophilus) microplus, R. annulatus and R. decoloratus Bm86 orthologs as secreted proteins in Pichia pastoris
    Mario Canales
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, 13071 Ciudad Real, Spain
    BMC Biotechnol 8:14. 2008
  5. pmc Sp110 transcription is induced and required by Anaplasma phagocytophilum for infection of human promyelocytic cells
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Infect Dis 7:110. 2007
  6. pmc Evidence of the role of tick subolesin in gene expression
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Genomics 9:372. 2008
  7. ncbi request reprint Targeting the tick-pathogen interface for novel control strategies
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Front Biosci 13:6947-56. 2008
  8. ncbi request reprint Overview: Ticks as vectors of pathogens that cause disease in humans and animals
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Front Biosci 13:6938-46. 2008
  9. ncbi request reprint RNA interference for the study and genetic manipulation of ticks
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Trends Parasitol 23:427-33. 2007
  10. ncbi request reprint Tick vaccines and the transmission of tick-borne pathogens
    J de la Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Vet Res Commun 31:85-90. 2007

Detail Information

Publications66

  1. pmc Fine-tuning the space, time, and host distribution of mycobacteria in wildlife
    Christian Gortazar
    IREC National Wildlife Research Institute CSIC UCLM JCCM, Ciudad Real, Spain
    BMC Microbiol 11:27. 2011
    ....
  2. pmc Allopatric speciation in ticks: genetic and reproductive divergence between geographic strains of Rhipicephalus (Boophilus) microplus
    Marcelo B Labruna
    Departamento de Medicina Veterinaria Preventiva e Saude Animal, Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    BMC Evol Biol 9:46. 2009
    ..microplus from Australia, Africa and America and the genetic diversity of strains from Australia, Asia, Africa and America...
  3. pmc Vaccination with recombinant Boophilus annulatus Bm86 ortholog protein, Ba86, protects cattle against B. annulatus and B. microplus infestations
    Mario Canales
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, Ciudad Real, Spain
    BMC Biotechnol 9:29. 2009
    ..Recently, the gene coding for B. annulatus Bm86 ortholog, Ba86, was cloned and the recombinant protein was secreted and purified from the yeast Pichia pastoris...
  4. pmc Expression of recombinant Rhipicephalus (Boophilus) microplus, R. annulatus and R. decoloratus Bm86 orthologs as secreted proteins in Pichia pastoris
    Mario Canales
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, 13071 Ciudad Real, Spain
    BMC Biotechnol 8:14. 2008
    ..The R. microplus Bm86 protective antigen has been produced by recombinant DNA technology and shown to protect cattle against tick infestations...
  5. pmc Sp110 transcription is induced and required by Anaplasma phagocytophilum for infection of human promyelocytic cells
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Infect Dis 7:110. 2007
    ..In this research, we hypothesized that Sp110 may be involved in the infection of human promyelocytic HL-60 cells with A. phagocytophilum...
  6. pmc Evidence of the role of tick subolesin in gene expression
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Genomics 9:372. 2008
    ..The objective of this study was to provide evidence for the role of subolesin in gene expression...
  7. ncbi request reprint Targeting the tick-pathogen interface for novel control strategies
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Front Biosci 13:6947-56. 2008
    ..Use of these molecular approaches will likely contribute to control measures that will notably reduce tick populations and tick-borne diseases in the future...
  8. ncbi request reprint Overview: Ticks as vectors of pathogens that cause disease in humans and animals
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Front Biosci 13:6938-46. 2008
    ..The molecular characterization of the tick-pathogen interface is rapidly advancing and providing new avenues for the development of novel control strategies for both tick infestations and their associated pathogens...
  9. ncbi request reprint RNA interference for the study and genetic manipulation of ticks
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Trends Parasitol 23:427-33. 2007
    ..It is probable that the knowledge gained from this experimental approach will contribute to development of vaccines to control tick infestations and the transmission of tick-borne pathogens...
  10. ncbi request reprint Tick vaccines and the transmission of tick-borne pathogens
    J de la Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Vet Res Commun 31:85-90. 2007
    ..These results have demonstrated that tick vaccines can be developed for control tick infestations and show promise for the prevention of the transmission of tick-borne pathogens...
  11. ncbi request reprint Sequence analysis of the msp4 gene of Anaplasma ovis strains
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Microbiol 119:375-81. 2007
    ..The results reported herein further confirm that A. ovis infection occurs in natural wild ruminant populations in Western United States and that bighorn sheep and mule deer may serve as wildlife reservoirs of A. ovis...
  12. ncbi request reprint Differential expression of the msp1alpha gene of Anaplasma marginale occurs in bovine erythrocytes and tick cells
    Jose C Garcia-Garcia
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Microbiol 98:261-72. 2004
    ..marginale for host cells. Variation in the expression of MSP1a may also contribute to phenotypic and antigenic changes in the pathogen...
  13. doi request reprint Identification of protective antigens by RNA interference for control of the lone star tick, Amblyomma americanum
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 28:1786-95. 2010
    ....
  14. ncbi request reprint Mapping of B-cell epitopes in the N-terminal repeated peptides of Anaplasma marginale major surface protein 1a and characterization of the humoral immune response of cattle immunized with recombinant and whole organism antigens
    Jose C Garcia-Garcia
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078 2007, USA
    Vet Immunol Immunopathol 98:137-51. 2004
    ..These results provide insight into the bovine antibody response against A. marginale and the role of MSP1a in protection of cattle against A. marginale infection...
  15. ncbi request reprint Analysis of world strains of Anaplasma marginale using major surface protein 1a repeat sequences
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Vet Microbiol 119:382-90. 2007
    ..marginale strains from various geographic locations worldwide. These results contribute to the understanding of the genetic diversity and evolution of A. marginale and tick-pathogen interactions...
  16. doi request reprint Differential expression of the tick protective antigen subolesin in anaplasma marginale- and A. phagocytophilum-infected host cells
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma, USA
    Ann N Y Acad Sci 1149:27-35. 2008
    ..The results reported herein further support the role of subolesin in Anaplasma-host interactions and suggest a putative role of subolesin in vaccines for the control of pathogen infection/multiplication in ticks...
  17. ncbi request reprint Antibodies to Anaplasma marginale major surface proteins 1a and 1b inhibit infectivity for cultured tick cells
    Edmour F Blouin
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078 2007, USA
    Vet Parasitol 111:247-60. 2003
    ..marginale for tick cells and may contribute to the continued infectivity of the pathogen for ticks...
  18. ncbi request reprint Functional genomic studies of tick cells in response to infection with the cattle pathogen, Anaplasma marginale
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Genomics 90:712-22. 2007
    ..The results of these studies demonstrated that a molecular mechanism occurs by which tick cell gene expression mediates the A. marginale developmental cycle and trafficking through ticks...
  19. ncbi request reprint Serologic and molecular characterization of Anaplasma species infection in farm animals and ticks from Sicily
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElory Hall, Stillwater, OK 74078, USA
    Vet Parasitol 133:357-62. 2005
    ..Definition of the diversity of Anaplasma spp. in Sicily reported, herein is fundamental to development of control strategies for A. marginale, A. ovis and A. phagocytophilum in Sicily...
  20. pmc Anaplasma marginale msp1alpha genotypes evolved under positive selection pressure but are not markers for geographic isolates
    Jose De La Fuente
    Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma 74708, USA
    J Clin Microbiol 41:1609-16. 2003
    ..marginale within Oklahoma could be explained by cattle movement and the maintenance of different genotypes by independent transmission events...
  21. pmc Reciprocal regulation of NF-kB (Relish) and Subolesin in the tick vector, Ixodes scapularis
    Victoria Naranjo
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma, United States of America
    PLoS ONE 8:e65915. 2013
    ..However, basic biological questions such as gene organization and regulation are largely unknown in ticks and other arthropod vectors...
  22. ncbi request reprint Recent studies on the characterization of Anaplasma marginale isolated from North American bison
    Katherine M Kocan
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Ann N Y Acad Sci 1026:114-7. 2004
    ..the results of this study demonstrated that these A. marginale isolates obtained from bison were similar to ones derived from naturally infected cattle...
  23. doi request reprint Silencing expression of the defensin, varisin, in male Dermacentor variabilis by RNA interference results in reduced Anaplasma marginale infections
    Katherine M Kocan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA
    Exp Appl Acarol 46:17-28. 2008
    ..This appears to be the first report of the silencing of expression of a defensin in ticks by RNAi that resulted in reduced A. marginale infections...
  24. ncbi request reprint Molecular epidemiology of human and bovine anaplasmosis in southern Europe
    Victoria Naranjo
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Ann N Y Acad Sci 1078:95-9. 2006
    ..The presence of concurrent infections in cattle and deer suggests that these pathogens may multiply in the same reservoir host and illustrates the complexity of the epidemiology of bovine and human anaplasmosis in this region...
  25. ncbi request reprint Capillary tube feeding system for studying tick-pathogen interactions of Dermacentor variabilis (Acari: Ixodidae) and Anaplasma marginale (Rickettsiales: Anaplasmataceae)
    Katherine M Kocan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
    J Med Entomol 42:864-74. 2005
    ....
  26. ncbi request reprint Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Anim Health Res Rev 6:75-89. 2005
    ..Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis...
  27. ncbi request reprint The tick protective antigen, 4D8, is a conserved protein involved in modulation of tick blood ingestion and reproduction
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 24:4082-95. 2006
    ....
  28. ncbi request reprint Vaccination of cattle with Anaplasma marginale derived from tick cell culture and bovine erythrocytes followed by challenge-exposure with infected ticks
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, 250 McElory Hall, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Vet Microbiol 89:239-251. 2002
    ..The cell culture-derived A. marginale shows promise for use as antigen in development of a new killed vaccine for anaplasmosis...
  29. pmc Glycosylation of Anaplasma marginale major surface protein 1a and its putative role in adhesion to tick cells
    Jose C Garcia-Garcia
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078 2007, USA
    Infect Immun 72:3022-30. 2004
    ..These results demonstrated that MSP1a and MSP1b are glycosylated and suggest that the glycosylation of MSP1a plays a role in the adhesion of A. marginale to tick cells...
  30. ncbi request reprint Characterization of three Ixodes scapularis cDNAs protective against tick infestations
    Consuelo Almazan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 23:4403-16. 2005
    ....
  31. ncbi request reprint Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, 74078 2007, Stillwater, OK, USA
    Vet Microbiol 91:265-83. 2003
    ..These studies demonstrated that the tandemly repeated region of the protein mediates the adhesive function of MSP1a...
  32. ncbi request reprint Reduction of tick infections with Anaplasma marginale and A. phagocytophilum by targeting the tick protective antigen subolesin
    Jose De La Fuente
    Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Parasitol Res 100:85-91. 2006
    ..These results suggest that subolesin appears to be a candidate vaccine antigen that may contribute to control of multiple tick species and the reduction of tick-borne pathogens...
  33. ncbi request reprint Applications of a cell culture system for studying the interaction of Anaplasma marginale with tick cells
    Edmour F Blouin
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Anim Health Res Rev 3:57-68. 2002
    ..marginale-tick interactions. Information gained from these studies may be applicable to other closely related tick-borne pathogens that have been propagated in the same tick cell line...
  34. ncbi request reprint Identification of protective antigens for the control of Ixodes scapularis infestations using cDNA expression library immunization
    Consuelo Almazan
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    Vaccine 21:1492-501. 2003
    ..Our studies demonstrated for the first time that cDNA expression library immunization (ELI) combined with sequence analysis is a powerful and efficient tool for identification of candidate antigens for use in vaccines against ticks...
  35. doi request reprint Expression of perilipin in human promyelocytic cells in response to Anaplasma phagocytophilum infection results in modified lipid metabolism
    Raúl Manzano-Román
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    J Med Microbiol 57:159-63. 2008
    ..The results of these studies expand our knowledge of the role of lipid metabolism in A. phagocytophilum infection and multiplication in HL-60 cells and suggest a mechanism by which A. phagocytophilum modulates lipid metabolism...
  36. ncbi request reprint Vaccination with recombinant tick antigens for the control of Ixodes scapularis adult infestations
    Consuelo Almazan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, 250 McElroy Hall, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 23:5294-8. 2005
    ..These antigens, and especially 4D8, appear to be good candidates for continued development of a vaccine for control of tick infestations...
  37. doi request reprint Functional genomics and evolution of tick-Anaplasma interactions and vaccine development
    Jose De La Fuente
    Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Parasitol 167:175-86. 2010
    ....
  38. ncbi request reprint Adhesion of outer membrane proteins containing tandem repeats of Anaplasma and Ehrlichia species (Rickettsiales: Anaplasmataceae) to tick cells
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Microbiol 98:313-22. 2004
    ..The results reported herein provide new information on the role of E. ruminantium "mucin" as an adhesin for tick cells and also suggest a role of glycans in adhesin molecules...
  39. pmc Silencing of genes involved in Anaplasma marginale-tick interactions affects the pathogen developmental cycle in Dermacentor variabilis
    Katherine M Kocan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Dev Biol 9:42. 2009
    ..marginale developmental cycle. These four genes encoded for putative glutathione S-transferase (GST), salivary selenoprotein M (SelM), H+ transporting lysosomal vacuolar proton pump (vATPase) and subolesin...
  40. ncbi request reprint Genetic diversity and molecular phylogeny of Anaplasma marginale isolates from Minas Gerais, Brazil
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Vet Parasitol 121:307-16. 2004
    ..marginale isolates, while MSP1a was found not to be a useful marker for phylogeographic characterization of A. marginale isolates...
  41. ncbi request reprint Synergistic effect of silencing the expression of tick protective antigens 4D8 and Rs86 in Rhipicephalus sanguineus by RNA interference
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Parasitol Res 99:108-13. 2006
    ..These results demonstrated the synergistic effect of the silencing expression of two tick protective genes. Inclusion of multiple tick protective antigens may, therefore, enhance the efficacy of tick vaccines...
  42. ncbi request reprint Gene expression profiling of human promyelocytic cells in response to infection with Anaplasma phagocytophilum
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Cell Microbiol 7:549-59. 2005
    ..phagocytophilum-infected HL-60 cells, thus expanding in a global manner the existing information on the response of mammalian cells to A. phagocytophilum infection...
  43. ncbi request reprint Adaptations of the tick-borne pathogen, Anaplasma marginale, for survival in cattle and ticks
    Katherine M Kocan
    Department of Veterinary Pathobiology, 250 McElroy Hall, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Exp Appl Acarol 28:9-25. 2002
    ..Infection and development of A. marginale in cattle and tick cells appears to differ and to be mediated by several surface proteins encoded from the small genome...
  44. ncbi request reprint Advances toward understanding the molecular biology of the Anaplasma-tick interface
    Katherine M Kocan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Front Biosci 13:7032-45. 2008
    ..Collectively, this information will likely lead to the development of dual target vaccines designed to protect vertebrates against tick infestations and prevent the transmission of pathogens...
  45. ncbi request reprint A ten-year review of commercial vaccine performance for control of tick infestations on cattle
    Jose De La Fuente
    Center for Veterinary Health Sciences, Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Anim Health Res Rev 8:23-8. 2007
    ....
  46. ncbi request reprint Anaplasmosis: focusing on host-vector-pathogen interactions for vaccine development
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Ann N Y Acad Sci 1078:416-23. 2006
    ..The screening for tick-protective antigens resulted in vaccine candidates reducing tick infestation, molting, and oviposition and affecting Anaplasma infection levels in ticks...
  47. ncbi request reprint Co-feeding studies of ticks infected with Anaplasma marginale
    Katherine M Kocan
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Parasitol 112:295-305. 2003
    ..marginale transmission. A. marginale infections in male ticks were not increased while co-feeding with females. Thus, co-feeding of adult Dermacentor spp. does not appear to influence the dynamics of A. marginale transmission...
  48. ncbi request reprint RNA interference screening in ticks for identification of protective antigens
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Parasitol Res 96:137-41. 2005
    ....
  49. ncbi request reprint Autocidal control of ticks by silencing of a single gene by RNA interference
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Biochem Biophys Res Commun 344:332-8. 2006
    ..Conservation of subolesin among tick species suggests that SAT may be useful for control of many medically and economically important tick species...
  50. pmc Characterization of Anaplasma marginale isolated from North American bison
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Stillwater, Oklahoma 74078, USA
    Appl Environ Microbiol 69:5001-5. 2003
    ..marginale bison isolate for cattle. The results of this study showed that these A. marginale isolates obtained from bison were similar to ones from naturally infected cattle...
  51. pmc Infection exclusion of the rickettsial pathogen anaplasma marginale in the tick vector Dermacentor variabilis
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Clin Diagn Lab Immunol 10:182-4. 2003
    ..These studies demonstrate that infection exclusion of A. marginale genotypes also occurs in naturally infected ticks, as well as in cattle and cultured tick cells, and results in establishment of only one genotype per tick...
  52. ncbi request reprint Genetic characterization of Anaplasma ovis strains from bighorn sheep in Montana
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    J Wildl Dis 42:381-5. 2006
    ..marginale in cattle herds in the western United States and worldwide. These results demonstrated that bighorn sheep may be a wildlife reservoir of A. ovis in Montana...
  53. ncbi request reprint Phylogeography of New World isolates of Anaplasma marginale based on major surface protein sequences
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Vet Microbiol 88:275-85. 2002
    ..marginale isolates. In contrast MSP1a sequences appeared to be rapidly evolving and these sequences may provide phylogeographic information only when numerous isolate MSP1a sequences are analyzed from a geographic area...
  54. doi request reprint Inoculation of white-tailed deer (Odocoileus virginianus) with Ap-V1 Or NY-18 strains of Anaplasma phagocytophilum and microscopic demonstration of Ap-V1 In Ixodes scapularis adults that acquired infection from deer as nymphs
    Mason V Reichard
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Vector Borne Zoonotic Dis 9:565-8. 2009
    ..Molted adult ticks maintained Ap-V1 infection as demonstrated by PCR and microscopy. We report, for the first time, a morphologic description of A. phagocytophilum in I. scapularis...
  55. pmc Antigens and alternatives for control of Anaplasma marginale infection in cattle
    Katherine M Kocan
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Clin Microbiol Rev 16:698-712. 2003
    ..marginale, combined with the new technologies, should contribute to the development of more effective vaccines for control and prevention of anaplasmosis...
  56. doi request reprint Defining the role of subolesin in tick cell culture by use of RNA interference
    Edmour F Blouin
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma, USA
    Ann N Y Acad Sci 1149:41-4. 2008
    ..RNAi is a powerful tool for studying tick gene function and will likely contribute to our understanding of the role that tick genes play in cell development and infection with pathogens...
  57. ncbi request reprint Advances in the identification and characterization of protective antigens for recombinant vaccines against tick infestations
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Expert Rev Vaccines 2:583-93. 2003
    ..Design of future tick vaccines should target multiple tick species, as well as interfere with the transmission of pathogens...
  58. doi request reprint The natural history of Anaplasma marginale
    Katherine M Kocan
    Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Vet Parasitol 167:95-107. 2010
    ..Recent advancements and new research methodologies should provide additional opportunities for development of new strategies for control and prevention of bovine anaplasmosis...
  59. ncbi request reprint Effect of tetracycline on development of Anaplasma marginale in cultured Ixodes scapularis cells
    Edmour F Blouin
    Department of Veterinary Pathobiology, 250 McElroy Hall, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vet Parasitol 107:115-26. 2002
    ..marginale in cultured tick cells. The Anaplasma-tick cell culture drug assay therefore, would be useful for screening and evaluating novel antibiotics for control of anaplasmosis...
  60. pmc Molecular characterization of Anaplasma platys strains from dogs in Sicily, Italy
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, 250 McElroy Hall, Oklahoma State University, Stillwater, OK 74078, USA
    BMC Vet Res 2:24. 2006
    ..The present study was designed to characterize A. patys strains in dogs from Palermo, Sicily, Italy, using a combination of PCR and sequence analysis of the 16S rDNA, heat shock operon groESL and citrate synthase (gltA) genes...
  61. ncbi request reprint Characterization of genetic diversity in Dermacentor andersoni (Acari: Ixodidae) with body size and weight polymorphism
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Exp Parasitol 109:16-26. 2005
    ..The results reported herein show that B ticks have a better reproductive success than S ticks and suggest partial reproductive isolation of S ticks...
  62. ncbi request reprint Transovarial silencing of the subolesin gene in three-host ixodid tick species after injection of replete females with subolesin dsRNA
    Katherine M Kocan
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, 250 McElroy Hall, Oklahoma State University, Stillwater, OK 74078, USA
    Parasitol Res 100:1411-5. 2007
    ..Transovarial RNAi appears to be a common mechanism in ixodid ticks and provides a simple method for the rapid characterization of tick genes involved in oviposition, embryogenesis, and larval development...
  63. pmc Sequence analysis of the msp4 gene of Anaplasma phagocytophilum strains
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    J Clin Microbiol 43:1309-17. 2005
    ..These results suggest that A. phagocytophilum strains from ruminants could share some common characteristics, including reservoirs and pathogenicity, which may be different from strains that infect humans...
  64. doi request reprint Sheep experimentally infected with a human isolate of Anaplasma phagocytophilum serve as a host for infection of Ixodes scapularis ticks
    Katherine M Kocan
    Dept of Veterinary Pathobiology, 250 McElroy Hall, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    Ticks Tick Borne Dis 3:147-53. 2012
    ..Sheep proved to be a good host for the production of I. scapularis infected with this human isolate of A. phagocytophilum, which can be used as a model for future studies of the tick/pathogen interface...
  65. pmc Infection of tick cells and bovine erythrocytes with one genotype of the intracellular ehrlichia Anaplasma marginale excludes infection with other genotypes
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Clin Diagn Lab Immunol 9:658-68. 2002
    ..marginale in bovine erythrocytes and tick cells, resulting in the establishment of only one genotype, and appears to be the first report of infection exclusion for Anaplasma and Ehrlichia species...
  66. ncbi request reprint The fossil record and the origin of ticks (Acari: Parasitiformes: Ixodida)
    Jose De La Fuente
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA
    Exp Appl Acarol 29:331-44. 2003
    ....