Michael S Davis

Summary

Affiliation: Oklahoma State University
Country: USA

Publications

  1. ncbi request reprint Prevalence of gastric lesions in racing Alaskan sled dogs
    M S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    J Vet Intern Med 17:311-4. 2003
  2. ncbi request reprint Recovery of muscle glycogen concentrations in sled dogs during prolonged exercise
    Erica McKenzie
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA
    Med Sci Sports Exerc 37:1307-12. 2005
  3. ncbi request reprint Airflow and device effects on aerosol delivery for large animals
    M S Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    J Vet Pharmacol Ther 24:57-60. 2001
  4. ncbi request reprint Sustained strenuous exercise increases intestinal permeability in racing Alaskan sled dogs
    Michael S Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    J Vet Intern Med 19:34-9. 2005
  5. ncbi request reprint Cold weather exercise and airway cytokine expression
    Michael S Davis
    Department of Physiological Sciences, Comparative Exercise Physiology Laboratory, College of Veterinary Medicine, 264 McElroy Hall, Stillwater, OK 74078, USA
    J Appl Physiol 98:2132-6. 2005
  6. ncbi request reprint Effect of training and rest on respiratory mechanical properties in racing sled dogs
    Michael Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Med Sci Sports Exerc 37:337-41. 2005
  7. ncbi request reprint Efficacy of omeprazole for the prevention of exercise-induced gastritis in racing Alaskan sled dogs
    M S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA
    J Vet Intern Med 17:163-6. 2003
  8. ncbi request reprint Repeated peripheral airway hyperpnea causes inflammation and remodeling in dogs
    Michael S Davis
    Department of Environmental Health Sciences, School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
    Med Sci Sports Exerc 35:608-16. 2003
  9. ncbi request reprint Modeling the acute- and late-phase responses to peripheral airway cooling and desiccation
    Michael S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater 74078, USA
    J Appl Physiol 93:195-200. 2002
  10. ncbi request reprint Eicosanoids modulate hyperpnea-induced late phase airway obstruction and hyperreactivity in dogs
    Michael S Davis
    Department of Environmental Health Sciences, School of Hygiene and Public Health, The Johns Hopkins Medical Institutions, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Respir Physiol 129:357-65. 2002

Research Grants

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Prevalence of gastric lesions in racing Alaskan sled dogs
    M S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    J Vet Intern Med 17:311-4. 2003
    ..049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large...
  2. ncbi request reprint Recovery of muscle glycogen concentrations in sled dogs during prolonged exercise
    Erica McKenzie
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA
    Med Sci Sports Exerc 37:1307-12. 2005
    ..To determine the depletion of muscle glycogen during five consecutive days of endurance exercise in Alaskan sled dogs consuming a high-fat, low-carbohydrate diet...
  3. ncbi request reprint Airflow and device effects on aerosol delivery for large animals
    M S Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    J Vet Pharmacol Ther 24:57-60. 2001
    ..Elimination of one-way valves between the aerosol source and the patient is expected to improve delivery of the aerosol in these patients...
  4. ncbi request reprint Sustained strenuous exercise increases intestinal permeability in racing Alaskan sled dogs
    Michael S Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    J Vet Intern Med 19:34-9. 2005
    ..We conclude that sustained strenuous exercise is associated with increased intestinal permeability, but the sucrose permeability test as we performed it did not correlate with visible gastric lesions...
  5. ncbi request reprint Cold weather exercise and airway cytokine expression
    Michael S Davis
    Department of Physiological Sciences, Comparative Exercise Physiology Laboratory, College of Veterinary Medicine, 264 McElroy Hall, Stillwater, OK 74078, USA
    J Appl Physiol 98:2132-6. 2005
    ..These results suggest that cold weather exercise can lead to asthmalike airway disease through the local induction of cytokines typical of the T(H)2 phenotype...
  6. ncbi request reprint Effect of training and rest on respiratory mechanical properties in racing sled dogs
    Michael Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Med Sci Sports Exerc 37:337-41. 2005
    ..These human athletes also have airway hyperresponsiveness, but airway function in sled dogs has not been measured...
  7. ncbi request reprint Efficacy of omeprazole for the prevention of exercise-induced gastritis in racing Alaskan sled dogs
    M S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA
    J Vet Intern Med 17:163-6. 2003
    ..However, further investigation regarding the cause and clinical relevance of diarrhea associated with omeprazole treatment must be conducted before omeprazole can be recommended for routine prophylactic treatment in these athletes...
  8. ncbi request reprint Repeated peripheral airway hyperpnea causes inflammation and remodeling in dogs
    Michael S Davis
    Department of Environmental Health Sciences, School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
    Med Sci Sports Exerc 35:608-16. 2003
    ..We used a canine model of hyperpnea with cold, dry air to test the hypothesis that repeated cooling and desiccation of peripheral airways can cause asthma-like pathology...
  9. ncbi request reprint Modeling the acute- and late-phase responses to peripheral airway cooling and desiccation
    Michael S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater 74078, USA
    J Appl Physiol 93:195-200. 2002
    ..However, our data suggest that mild inflammation can be induced with relatively lower challenge severity...
  10. ncbi request reprint Eicosanoids modulate hyperpnea-induced late phase airway obstruction and hyperreactivity in dogs
    Michael S Davis
    Department of Environmental Health Sciences, School of Hygiene and Public Health, The Johns Hopkins Medical Institutions, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Respir Physiol 129:357-65. 2002
    ..The late phase changes in airway mechanics are related to the hyperventilation-induced release of both prostaglandins and leukotrienes, and appear to be independent of the late phase infiltration of inflammatory cells...
  11. doi request reprint Effects of training and strenuous exercise on hematologic values and peripheral blood leukocyte subsets in racing sled dogs
    Michael S Davis
    Comparative Exercise Physiology Laboratory, 264 McElroy Hall, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    J Am Vet Med Assoc 232:873-8. 2008
    ..To determine the effects of training and sustained submaximal exercise on hematologic values in racing sled dogs...
  12. ncbi request reprint Efficacy of famotidine for the prevention of exercise-induced gastritis in racing Alaskan sled dogs
    Katherine K Williamson
    Departments of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA
    J Vet Intern Med 21:924-7. 2007
    ..The frequent feeding of sled dogs during competition likely results in decreased absorption of omeprazole and, thereby, decreased efficacy...
  13. ncbi request reprint Serum chemistry alterations in Alaskan sled dogs during five successive days of prolonged endurance exercise
    Erica C McKenzie
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    J Am Vet Med Assoc 230:1486-92. 2007
    ..To determine the impact of successive days of endurance exercise on select serum chemistry values in conditioned Alaskan sled dogs...
  14. ncbi request reprint Influx of neutrophils and persistence of cytokine expression in airways of horses after performing exercise while breathing cold air
    Michael S Davis
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Am J Vet Res 68:185-9. 2007
    ..To determine effects of exercise performed while breathing cold air on expression of cytokines and influx of neutrophils in airways of horses...
  15. doi request reprint Assessment of alterations in triglyceride and glycogen concentrations in muscle tissue of Alaskan sled dogs during repetitive prolonged exercise
    Erica C McKenzie
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Am J Vet Res 69:1097-103. 2008
    ..To assess changes in muscle glycogen (MG) and triglyceride (MT) concentrations in aerobically conditioned sled dogs during prolonged exercise...
  16. ncbi request reprint Racing Alaskan sled dogs as a model of "ski asthma"
    Michael S Davis
    Department of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Am J Respir Crit Care Med 166:878-82. 2002
    ..Our findings support the hypothesis that strenuous exercise in cold environments can lead to lower airway disease and suggest that racing sled dogs may be a useful naturally occurring animal model of the analogous human disease...
  17. ncbi request reprint Pharmacokinetics of acyclovir after single intravenous and oral administration to adult horses
    Bradford G Bentz
    Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater 74078, USA
    J Vet Intern Med 20:589-94. 2006
    ..The results of this study do not support a therapeutic benefit for the oral administration of acyclovir up to doses of 20 mg/kg...
  18. ncbi request reprint Effect of strenuous exercise on urine concentrations of homovanillic acid, cortisol, and vanillylmandelic acid in sled dogs
    Lawren L Durocher
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
    Am J Vet Res 68:107-11. 2007
    ..To determine whether prolonged exercise by conditioned sled dogs affects urine concentrations of homovanillic acid (a metabolite of dopamine), vanillylmandelic acid (a metabolite of norepinephrine and epinephrine), and cortisol...
  19. ncbi request reprint Evidence-based respiratory medicine in horses
    Katherine K Williamson
    Department of Physiological Sciences, Oklahoma State University Center for Veterinary Health Sciences, Stillwater, OK 74078, USA
    Vet Clin North Am Equine Pract 23:215-27. 2007
    ....
  20. ncbi request reprint Temporal relationship between gastrointestinal protein loss, gastric ulceration or erosion, and strenuous exercise in racing Alaskan sled dogs
    Michael Davis
    Department of Physiological Sciences, Texas A and M University, College Station, USA
    J Vet Intern Med 20:835-9. 2006
    ..Alterations in the appearance and function of gastrointestinal mucosa are common after strenuous exercise. However, the duration of exercise required to alter the gastrointestinal mucosa has not been reported...
  21. ncbi request reprint Xylazine-induced attenuation of dorsal displacement of the soft palate associated with epiglottic dysfunction in a horse
    Vivienne E Duggan
    Department of Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    J Am Vet Med Assoc 221:399-401, 368. 2002
    ..It was also unusual that the response outlasted the sedative effect of the drug...
  22. ncbi request reprint Airway surface fluid desiccation during isocapnic hyperpnea
    Michael S Davis
    J Appl Physiol 94:2545-6; author reply 2546-7. 2003

Research Grants7

  1. ANIMAL MODELS OF COLD AIR-INDUCED AIRWAY DISEASE
    Michael Davis; Fiscal Year: 2004
    ..The investigators will use these same measurements to determine the changes in pulmonary mechanics and airway inflammation in dogs that perform repeated exercise in frigid environments. ..
  2. NCRR Training Grant for Veterinary Students in Research
    Michael Davis; Fiscal Year: 2006
    ..Over a three-year period this program will contribute nine comparative medical scientists with veterinary medical degrees who are well trained in animal-oriented, hypothesis-based research. ..