Scott A Kelly

Summary

Affiliation: Ohio Wesleyan University
Country: USA

Publications

  1. doi request reprint Exercise training effects on hypoxic and hypercapnic ventilatory responses in mice selected for increased voluntary wheel running
    Scott A Kelly
    Ohio Wesleyan University, Schimmel Conrades Science Center 346, 61 S Sandusky Street, Delaware, OH 43015, USA
    Exp Physiol 99:403-13. 2014
  2. doi request reprint Phenotypic plasticity: molecular mechanisms and adaptive significance
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
    Compr Physiol 2:1417-39. 2012
  3. pmc Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain
    Scott A Kelly
    Department of Genetics, Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Genetics 191:643-54. 2012
  4. pmc Genetic architecture of voluntary exercise in an advanced intercross line of mice
    Scott A Kelly
    Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Rd, Chapel Hill, NC 27599 7264, USA
    Physiol Genomics 42:190-200. 2010
  5. pmc Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Physiol Genomics 43:199-212. 2011
  6. pmc A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice
    Scott A Kelly
    Department of Zoology, Ohio Wesleyan University, Delaware, Ohio 43015
    Genetics 195:1385-95. 2013
  7. pmc Parent-of-origin effects on voluntary exercise levels and body composition in mice
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Physiol Genomics 40:111-20. 2010
  8. pmc Fine mapping of "mini-muscle," a recessive mutation causing reduced hindlimb muscle mass in mice
    John Hartmann
    Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA
    J Hered 99:679-87. 2008
  9. pmc Genetic determinants of voluntary exercise
    Scott A Kelly
    Department of Zoology, Ohio Wesleyan University, Delaware, OH 43015, USA
    Trends Genet 29:348-57. 2013
  10. doi request reprint Advances in comparative genetics: influence of genetics on obesity
    Wendy Foulds Mathes
    Department of Genetics, University of North Carolina at Chapel Hill, NC, USA
    Br J Nutr 106:S1-10. 2011

Detail Information

Publications10

  1. doi request reprint Exercise training effects on hypoxic and hypercapnic ventilatory responses in mice selected for increased voluntary wheel running
    Scott A Kelly
    Ohio Wesleyan University, Schimmel Conrades Science Center 346, 61 S Sandusky Street, Delaware, OH 43015, USA
    Exp Physiol 99:403-13. 2014
    ..We tentatively conclude that exercise 'training' alters respiratory behaviours, but these changes may not be necessary to achieve high levels of wheel running...
  2. doi request reprint Phenotypic plasticity: molecular mechanisms and adaptive significance
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
    Compr Physiol 2:1417-39. 2012
    ..Finally, we highlight examples of phenotypic plasticity from a human health perspective and underscore the use of mouse models as a powerful tool in understanding the genetic architecture of phenotypic plasticity...
  3. pmc Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain
    Scott A Kelly
    Department of Genetics, Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Genetics 191:643-54. 2012
    ..These results develop a potential initial model of the underlying functional genomic architecture of predisposition to voluntary exercise and its effects on body weight and composition within a neurophysiological framework...
  4. pmc Genetic architecture of voluntary exercise in an advanced intercross line of mice
    Scott A Kelly
    Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Rd, Chapel Hill, NC 27599 7264, USA
    Physiol Genomics 42:190-200. 2010
    ....
  5. pmc Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Physiol Genomics 43:199-212. 2011
    ..Finally, we present unique QTL providing insight regarding variation in weight loss and reduction in adiposity in response to exercise...
  6. pmc A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice
    Scott A Kelly
    Department of Zoology, Ohio Wesleyan University, Delaware, Ohio 43015
    Genetics 195:1385-95. 2013
    ..Using next-generation sequencing, our approach can be extended to identify causative mutations arising in mouse inbred lines and thus offers a great avenue to overcome one of the most challenging steps in quantitative genetics. ..
  7. pmc Parent-of-origin effects on voluntary exercise levels and body composition in mice
    Scott A Kelly
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Physiol Genomics 40:111-20. 2010
    ..e., X-linked or mtDNA variations), epigenetic (i.e., genomic imprinting), and environmental (i.e., in utero environment or maternal care) phenomena potentially modulating these effects...
  8. pmc Fine mapping of "mini-muscle," a recessive mutation causing reduced hindlimb muscle mass in mice
    John Hartmann
    Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA
    J Hered 99:679-87. 2008
    ..Identification of the genetic variation that underlies MM could potentially be very important in understanding both normal muscle function and disregulation of muscle physiology leading to disease...
  9. pmc Genetic determinants of voluntary exercise
    Scott A Kelly
    Department of Zoology, Ohio Wesleyan University, Delaware, OH 43015, USA
    Trends Genet 29:348-57. 2013
    ..Finally, we explore potential regulation of physical activity through epigenetic mechanisms, including those that persist across multiple generations...
  10. doi request reprint Advances in comparative genetics: influence of genetics on obesity
    Wendy Foulds Mathes
    Department of Genetics, University of North Carolina at Chapel Hill, NC, USA
    Br J Nutr 106:S1-10. 2011
    ..Knowledge obtained from advances in mouse models will inform human health and provide insight into inter-individual variability in the aetiology of obesity-related diseases...