Research Topics
| SCOTT HOOPERSummaryAffiliation: Ohio University Country: USA Publications
Research Grants
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Detail Information
Publications
Motor neuron activity is often insufficient to predict motor responseS L Hooper
Department of Biological Sciences, Irvine Hall, Ohio University, Athens, OH 45701, USA
Curr Opin Neurobiol 10:676-82. 2000..These advances include a theoretical analysis of the neuromuscular transform and a deeper understanding of the functional effects of non-linear contractile responses, slow muscle relaxation, and neuromodulation...
Neural control of unloaded leg posture and of leg swing in stick insect, cockroach, and mouse differs from that in larger animalsScott L Hooper
Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA
J Neurosci 29:4109-19. 2009..Limb size may thus be as great a determinant as phylogenetic position of unloaded limb motor control strategy...
Slow conductances could underlie intrinsic phase-maintaining properties of isolated lobster (Panulirus interruptus) pyloric neuronsScott L Hooper
Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA
J Neurosci 29:1834-45. 2009..These data suggest that slow conductances or similar slow processes such as changes in intracellular Ca(2+) concentration could underlie phase maintenance in pyloric network neurons...- Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscleScott L Hooper
Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, OH 45701, United States
Prog Neurobiol 86:72-127. 2008..The molecular basis of the stretch activation underlying asynchronous muscle activity, however, remains unresolved... - Slow temporal filtering may largely explain the transformation of stick insect (Carausius morosus) extensor motor neuron activity into muscle movementScott L Hooper
Department of Biological Sciences, Irvine Hall, Ohio University, Athens, OH 45701, USA
J Neurophysiol 98:1718-32. 2007.... - Different motor neuron spike patterns produce contractions with very similar rises in graded slow musclesScott L Hooper
Department of Biological Sciences, Irvine Hall, Ohio University, Athens, OH 45701, USA
J Neurophysiol 97:1428-44. 2007..Although alternative explanations are possible, the simplest interpretation of these data is that extensor motor neuron firing during leg swing is not tightly controlled... - Natural neural output that produces highly variable locomotory movementsScott L Hooper
Department of Biological Sciences, Ohio University, Athens, OH 45701, USA
J Neurophysiol 96:2072-88. 2006.... - Movement control: dedicated or distributed?Scott L Hooper
Department of Biological Sciences, Ohio University, Athens 45701, USA
Curr Biol 15:R878-80. 2005..Neural networks in which 'commands' spread 'horizontally' across multiple neurons have been believed to mediate motor pattern variation. A recent study shows that dedicated 'vertical' neural pathways can also underlie these variations... - Invertebrate muscles: muscle specific genes and proteinsScott L Hooper
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
Physiol Rev 85:1001-60. 2005..Fully achieving these goals, however, will require examination of a much broader range of species than has been heretofore performed... - Behavioral plasticity: modulation occurs across timeScott L Hooper
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
Curr Biol 14:R190-1. 2004..Some neurons modulate their own networks. This 'intrinsic' modulatory feedback implies that a network's history could partially determine its present activity... - Crustacean motor pattern generator networksScott L Hooper
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
Neurosignals 13:50-69. 2004.... - A computational role for slow conductances: single-neuron models that measure durationScott L Hooper
Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701 USA
Nat Neurosci 5:552-6. 2002..These data, and the widespread presence of slow conductances in nervous systems, suggest that slow conductances might play a major role in duration measurement... - Combinatorial and cross-fiber averaging transform muscle electrical responses with a large stochastic component into deterministic contractionsNeil J Hoover
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
J Neurosci 22:1895-904. 2002..The data reported here provide further support that bursting presynaptic activity could make such synapses functionally deterministic as well... - Quantification of gastric mill network effects on a movement related parameter of pyloric network output in the lobsterJeff B Thuma
Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA
J Neurophysiol 87:2372-84. 2002..In addition to providing data necessary to predict pyloric movement, this work shows how pattern-based analysis can successfully quantify interactions between nonphase-locked networks... - Lobster (Panulirus interruptus) pyloric muscles express the motor patterns of three neural networks, only one of which innervates the musclesJeff B Thuma
Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA
J Neurosci 23:8911-20. 2003.... - Follower neurons in lobster (Panulirus interruptus) pyloric network regulate pacemaker period in complementary waysAdam L Weaver
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
J Neurophysiol 89:1327-38. 2003..These data show that follower neurons in pacemaker networks can play central roles in controlling pacemaker period and suggest that in some cases specific functions can be assigned to individual network neurons... - Quantification of cardiac sac network effects on a movement-related parameter of pyloric network output in the lobsterJeff B Thuma
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
J Neurophysiol 89:745-53. 2003..These data provide the quantitative description of cardiac sac effects on pyloric activity necessary to predict pyloric movement from pyloric neural output... - Direct evidence that stomatogastric (Panulirus interruptus) muscle passive responses are not due to background actomyosin cross-bridgesJeffrey B Thuma
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, OH 45701, USA
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 196:649-57. 2010..Thiourea may therefore provide a convenient technique to measure muscle electrical responses to motor nerve input without the confounding difficulties caused by muscle contraction... - Pyloric neuron morphology in the stomatogastric ganglion of the lobster, Panulirus interruptusJeffrey B Thuma
Department of Biological Sciences, Ohio University, Athens, Ohio, USA
Brain Behav Evol 73:26-42. 2009..These data are similar to those previously obtained in Brachyura and Astacidea. It thus appears that, despite their long evolutionary separation, neuron morphology in these three infraorders has not greatly diverged... - Using complicated, wide dynamic range driving to develop models of single neurons in single recording sessionsKevin H Hobbs
Department of Biological Sciences, Ohio University, Athens, OH 45701, USA
J Neurophysiol 99:1871-83. 2008..The method uses only standard experimental and computational techniques, could be easily extended to optimize conductance parameters other than g(max), and should be readily applicable to real neurons... - Muscle anatomy is a primary determinant of muscle relaxation dynamics in the lobster (Panulirus interruptus) stomatogastric systemJeffrey B Thuma
Department of Biological Sciences, Ohio University, 107 Irvine Hall, Athens, OH 45701, USA
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:1101-13. 2007..The stomatogastric system may thus be an excellent model system for studying the mechanisms regulating muscle sarcomere number... - Relating network synaptic connectivity and network activity in the lobster (Panulirus interruptus) pyloric networkAdam L Weaver
Neuroscience Program, Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
J Neurophysiol 90:2378-86. 2003.... - Motor control: the importance of stiffnessScott L Hooper
Department of Biological Sciences, Ohio University, Athens, 45701, USA
Curr Biol 16:R283-5. 2006.... - High-resolution computed tomography of lobster (Panulirus interruptus) stomachKevin H Hobbs
Department of Biological Sciences, Irvine Hall, Ohio University, Athens, Ohio 45701, USA
J Morphol 270:1029-41. 2009..Notably absent are close-apposition, morphologically specialized joints such as hinge or ball-and-socket joints... - Multiple routes to similar network outputScott L Hooper
Nat Neurosci 7:1287-8. 2004 - Variation is the spice of life. Focus on "Cycle-to-cycle variability of neuromuscular activity in Aplysia feeding behavior"Scott L Hooper
J Neurophysiol 92:40-1. 2004
Research Grants
- PHASE MAINTENANCE, NEURON PROPERTIES TO MUSCLE RESPONSESCOTT HOOPER; Fiscal Year: 2002..The experimental advantages of this preparation allow all the network's neurons to be individually characterized, and the system to be studied on all levels from membrane conductances to muscle contraction. ..
- Phase Maintenance: Neuron Properties to Muscle ResponseSCOTT HOOPER; Fiscal Year: 2007..The research will be performed in a well known model system, the pyloric neuromuscular system, with a proven track record of discovering neurobiological principles of wide applicability, including to humans. ..