Research Topics
| Brian C ClarkSummaryAffiliation: Ohio University Country: USA Publications
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Detail Information
Publications
Effects of persistent Mal de debarquement syndrome on balance, psychological traits, and motor cortex exctiabilityBrian C Clark
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA
J Clin Neurosci 20:446-50. 2013..These findings help characterize MdDS, and provide insight into the physiology of MdDS...
What is dynapenia?Brian C Clark
Ohio Musculoskeletal and Neurological Institute OMNI and Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
Nutrition 28:495-503. 2012..In addition, we address the role of nutrition in the muscular and neurologic systems for the preservation of muscle strength throughout the life span...
The biology of manual therapiesBrian C Clark
Ohio University, OMNI and Department of Biomedical Sciences, 236 Irvine Hall, Athens, OH 45701, USA
J Am Osteopath Assoc 112:617-29. 2012..The authors have tested this hypothesis and summarize their work on the biology of manual therapies...- Age-related changes in motor cortical properties and voluntary activation of skeletal muscleBrian C Clark
Ohio University, Department of Biomedical Sciences, Athens, OH 45701, USA
Curr Aging Sci 4:192-9. 2011..We also provide perspectives on scientific and clinical questions that need to be addressed in the near future... - Effect of prolonged unweighting of human skeletal muscle on neuromotor force controlBrian C Clark
Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, 211 Irvine Hall, Athens, OH 45701, USA
Eur J Appl Physiol 100:53-62. 2007.... - Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with menBrian C Clark
Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University, Athens, OH 45701, USA
Arch Phys Med Rehabil 90:178-80. 2009..To investigate sex-related differences in the loss and recovery of voluntary muscle strength after immobilization... - Neuromuscular plasticity during and following 3 wk of human forearm cast immobilizationBrian C Clark
Dept of Biomedical Sciences, Ohio Univ College of Osteopathic Medicine, Athens, OH 45701, USA
J Appl Physiol 105:868-78. 2008.... - Sarcopenia =/= dynapeniaBrian C Clark
Department of Biomedical Sciences, Ohio University, 211 Irvine Hall, Athens, OH 45701, USA
J Gerontol A Biol Sci Med Sci 63:829-34. 2008..Rather, we propose that alternative mechanisms underlie dynapenia (i.e., alterations in contractile properties or neurologic function), and urge that greater attention be paid to these variables in determining their role in dynapenia... - Immobilization-induced increase in fatigue resistance is not explained by changes in the muscle metaboreflexBrian C Clark
Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, 211 Irvine Hall, Ohio University, Athens, Ohio 45701, USA
Muscle Nerve 38:1466-73. 2008..05). These findings indicate that the augmentation of time to task failure with immobilization is not associated with changes in the pressor or metaboreflex responses... - In vivo alterations in skeletal muscle form and function after disuse atrophyBrian C Clark
Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, OH 45701, USA
Med Sci Sports Exerc 41:1869-75. 2009..Lastly, emerging data warranting further inquiry into the modulating role of biological sex on disuse-induced adaptations are also discussed... - Cast immobilization increases long-interval intracortical inhibitionBrian C Clark
Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA
Muscle Nerve 42:363-72. 2010..63). The H-reflex increased following immobilization. These findings suggest that immobilization increases intracortical inhibition during contraction, and this increase is primarily mediated by GABA(B) receptors... - Muscle functional magnetic resonance imaging and acute low back pain: a pilot study to characterize lumbar muscle activity asymmetries and examine the effects of osteopathic manipulative treatmentBrian C Clark
Institute for Neuromusculoskeletal Research, Ohio University College of Osteopathic Medicine, Northfield, OH, USA
Osteopath Med Prim Care 3:7. 2009.... - Relative safety of 4 weeks of blood flow-restricted resistance exercise in young, healthy adultsB C Clark
Department of Biomedical Sciences, Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA
Scand J Med Sci Sports 21:653-62. 2011.... - Neurophysiologic effects of spinal manipulation in patients with chronic low back painBrian C Clark
Ohio Musculoskeletal and Neurological Institute OMNI, Ohio University, 236 Irvine Hall, Athens, OH 45701, USA
BMC Musculoskelet Disord 12:170. 2011.... - Men and women exhibit a similar time to task failure for a sustained, submaximal elbow extensor contractionDouglas J Dearth
Institute for Neuromusculoskeletal Research, Ohio University, Athens, OH, USA
Eur J Appl Physiol 108:1089-98. 2010.... - Older adults exhibit more intracortical inhibition and less intracortical facilitation than young adultsMarisa McGinley
Institute for Neuromusculoskeletal Research, Ohio University, United States Department of Biomedical Sciences, Ohio University, United States
Exp Gerontol 45:671-8. 2010..Aging results in decreased neuromuscular function, which is likely associated with neurologic alterations. At present little is known regarding age-related changes in intracortical properties... - Delayed-onset muscle soreness induced by low-load blood flow-restricted exerciseJonathan D Umbel
Institute for Neuromusculoskeletal Research, Ohio University, Athens, OH, USA
Eur J Appl Physiol 107:687-95. 2009..7% decrease vs. 3.4 +/- 2.5% decrease) (p <or= 0.05). These data suggest that knee extension BFR exercise induces mild DOMS and that BFR exercise elicits muscle damage under atypical conditions with low-tension concentric contractions... - Non-thrust manual therapy reduces erector spinae short-latency stretch reflex asymmetries in patients with chronic low back painDavid A Goss
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH 45701, USA
J Electromyogr Kinesiol 22:663-9. 2012..Ultimately, developing a better understanding of the physiologic effects of manual therapies will assist in optimizing treatment strategies for patients with LBP... - Time to task failure of trunk extensor muscles differs with load typeJames S Thomas
School of Rehabilitation and Communication Sciences, Division of Physical Therapy, Ohio University, Athens 45701, USA
J Mot Behav 43:27-9. 2011..This could be an important issue in understanding the mechanisms of task failure, and the endurance capacity of the trunk extensor muscles... - Fatigue-induced changes in phasic muscle activation patterns during dynamic trunk extension exerciseBrian C Clark
Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, Ohio 45701, USA
Am J Phys Med Rehabil 86:373-9. 2007..To investigate the influence of fatigue on phasic muscle-activation patterns during dynamic trunk extension exercise... - Novel methods for quantifying neurophysiologic properties of the human lumbar paraspinal musclesDavid A Goss
Institute for Neuromusculoskeletal Research, Ohio University, United States
J Neurosci Methods 194:329-35. 2011..05). These innovative methods may be useful in studying basic physiology, the pathology of low back pain, as well as the mechanisms of action of treatment interventions... - Functional consequences of sarcopenia and dynapenia in the elderlyBrian C Clark
Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
Curr Opin Clin Nutr Metab Care 13:271-6. 2010.... - Social, societal, and economic burden of mal de debarquement syndromeAllison Macke
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH 45701, USA
J Neurol 259:1326-30. 2012..MdDS negatively and dramatically impacts QOL, and also imposes a substantial economic burden on MdDS patients. These findings underscore the need for further basic and clinical research on MdDS... - Aging and muscle: a neuron's perspectiveTodd M Manini
Institute of Aging and the Department of Aging and Geriatric Research, University of Florida, Gainesville, Florida 32611, USA
Curr Opin Clin Nutr Metab Care 16:21-6. 2013..Here, we briefly discuss age-related impairments in the brain and peripheral nerve structures that may theoretically lead to muscle weakness in old age... - Development of a neuromuscular electrical stimulation protocol for sprint trainingDavid W Russ
Laboratory for Integrative Muscle Biology, Division of Physical Therapy, Ohio University, School of Rehabilitation and Communication Sciences, Athens, OH 45701, USA
Med Sci Sports Exerc 44:1810-9. 2012..The purpose of this report was to describe the development of a tolerable neuromuscular electrical stimulation (NMES) protocol that induces skeletal muscle adaptations similar to those observed with sprint training... - Evolving concepts on the age-related changes in "muscle quality"David W Russ
Ohio Musculoskeletal and Neurological Institute OMNI, Ohio University, 236 Irvine Hall, Athens, OH, 45701, USA
J Cachexia Sarcopenia Muscle 3:95-109. 2012.... - Reliability of techniques to assess human neuromuscular function in vivoBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, 820 Comstock Avenue, Room 201, Syracuse, NY 13244, USA
J Electromyogr Kinesiol 17:90-101. 2007..In conclusion, while the reliability differed between the various measures, in general it was rather high even when the testing sessions are separated by a relatively long duration of time... - Leg muscle activity during walking with assistive devices at varying levels of weight bearingBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
Arch Phys Med Rehabil 85:1555-60. 2004..To evaluate the muscle activation patterns at varying levels of weight-bearing forces during assisted walking with an axillary crutch and a recently designed device that allows weight transfer through the pelvic girdle (ED Walker)... - Sex differences in muscle fatigability and activation patterns of the human quadriceps femorisBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
Eur J Appl Physiol 94:196-206. 2005.... - Gender differences in skeletal muscle fatigability are related to contraction type and EMG spectral compressionBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse 13244, USA
J Appl Physiol 94:2263-72. 2003..45 vs. 0.19). These findings suggest that gender differences in muscle fatigue are influenced by muscle contraction type and frequency shifts in the EMG signal but not by alterations in the synergistic activation patterns... - Quantification of the corticospinal silent period evoked via transcranial magnetic stimulationLeatha A Damron
Department of Physical Therapy, SUNY Upstate Medical University, United States
J Neurosci Methods 173:121-8. 2008..99). These results suggest that SPs evoked with a stimulus intensity >or=30% AMT and quantified visually by defining the start of the SP at stimulus delivery or the start of the MEP be utilized to decrease the between visit variability... - Adaptations in human neuromuscular function following prolonged unweighting: II. Neurological properties and motor imagery efficacyBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, New York, USA
J Appl Physiol 101:264-72. 2006.... - Adaptations in human neuromuscular function following prolonged unweighting: I. Skeletal muscle contractile properties and applied ischemia efficacyBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, New York, USA
J Appl Physiol 101:256-63. 2006..These findings suggest that unweighting alters the contractile properties involved in the excitation-contraction coupling processes and that Isc impacts the sarcolemma... - Derecruitment of the lumbar musculature with fatiguing trunk extension exerciseBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse, New York 13244, USA
Spine (Phila Pa 1976) 28:282-7. 2003..This was a descriptive study involving 20 healthy individuals... - Electromyographic activity of the lumbar and hip extensors during dynamic trunk extension exerciseBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, 820 Comstock Avenue, Room 201, Syracuse, NY 13244, USA
Arch Phys Med Rehabil 83:1547-52. 2002..To evaluate the effects of exercise intensity and multiple sets on muscle activation patterns during trunk extension exercise... - Kinesthetic motor imagery and spinal excitability: the effect of contraction intensity and spatial localizationPatrick M Cowley
Musculoskeletal Research Laboratory, Department of Exercise Science at Syracuse University, 201 Women s Building, 820 Comstock Ave, Syracuse, NY 13244, USA
Clin Neurophysiol 119:1849-56. 2008..Our research questions required two experiments... - Growth hormone and muscle function responses to skeletal muscle ischemiaJoseph R Pierce
Department of Exercise Science, Syracuse University, Syracuse, New York, USA
J Appl Physiol 101:1588-95. 2006..In conclusion, ISC coupled with resistance exercise acutely increases GH levels and reduces MVC, whereas ISC alone decreases force capacity, without alterations in GH levels... - The use of magnetic resonance imaging to evaluate lumbar muscle activity during trunk extension exercise at varying intensitiesJohn M Mayer
Department of Exercise Science, Syracuse University, Syracuse, New York, USA
Spine (Phila Pa 1976) 30:2556-63. 2005..Descriptive, repeated measures analysis of exercise-induced changes in lumbar muscle transverse relaxation time (T2)... - Resistance and functional training reduces knee extensor position fluctuations in functionally limited older adultsTodd M Manini
Musculoskeletal Research Laboratory, Syracuse University, Syracuse, NY, USA
Eur J Appl Physiol 95:436-46. 2005.... - Evaluation of spastic muscle in stroke survivors using magnetic resonance imaging and resistance to passive motionLori L Ploutz-Snyder
Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA
Arch Phys Med Rehabil 87:1636-42. 2006..To assess the feasibility of using magnetic resonance imaging (MRI) and resistance to passive movement to evaluate spastic muscle... - Reduced physical activity increases intermuscular adipose tissue in healthy young adultsTodd M Manini
Department of Aging and Geriatrics, Institute on Aging, University of Florida, Gainesville, FL 32611 0107, USA
Am J Clin Nutr 85:377-84. 2007..Although several studies have described adaptations in muscle after reduced physical activity, the change in IMAT in healthy young adults is unknown... - Effects of exercise load and blood-flow restriction on skeletal muscle functionSummer B Cook
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244 5040, USA
Med Sci Sports Exerc 39:1708-13. 2007..It is unclear how occlusion pressure, exercise intensity, and occlusion duration interact, or which combination of these factors results in the most potent muscle stimulus...