Brian C Clark

Summary

Affiliation: Ohio University
Country: USA

Publications

  1. doi request reprint Effects of persistent Mal de debarquement syndrome on balance, psychological traits, and motor cortex exctiability
    Brian C Clark
    Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA
    J Clin Neurosci 20:446-50. 2013
  2. pmc What is dynapenia?
    Brian C Clark
    Ohio Musculoskeletal and Neurological Institute OMNI and Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
    Nutrition 28:495-503. 2012
  3. ncbi request reprint The biology of manual therapies
    Brian C Clark
    Ohio University, OMNI and Department of Biomedical Sciences, 236 Irvine Hall, Athens, OH 45701, USA
    J Am Osteopath Assoc 112:617-29. 2012
  4. pmc Age-related changes in motor cortical properties and voluntary activation of skeletal muscle
    Brian C Clark
    Ohio University, Department of Biomedical Sciences, Athens, OH 45701, USA
    Curr Aging Sci 4:192-9. 2011
  5. ncbi request reprint Effect of prolonged unweighting of human skeletal muscle on neuromotor force control
    Brian C Clark
    Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, 211 Irvine Hall, Athens, OH 45701, USA
    Eur J Appl Physiol 100:53-62. 2007
  6. doi request reprint Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with men
    Brian C Clark
    Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University, Athens, OH 45701, USA
    Arch Phys Med Rehabil 90:178-80. 2009
  7. doi request reprint Immobilization-induced increase in fatigue resistance is not explained by changes in the muscle metaboreflex
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, 211 Irvine Hall, Ohio University, Athens, Ohio 45701, USA
    Muscle Nerve 38:1466-73. 2008
  8. ncbi request reprint Sarcopenia =/= dynapenia
    Brian C Clark
    Department of Biomedical Sciences, Ohio University, 211 Irvine Hall, Athens, OH 45701, USA
    J Gerontol A Biol Sci Med Sci 63:829-34. 2008
  9. pmc Cast immobilization increases long-interval intracortical inhibition
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA
    Muscle Nerve 42:363-72. 2010
  10. doi request reprint Neuromuscular plasticity during and following 3 wk of human forearm cast immobilization
    Brian C Clark
    Dept of Biomedical Sciences, Ohio Univ College of Osteopathic Medicine, Athens, OH 45701, USA
    J Appl Physiol (1985) 105:868-78. 2008

Collaborators

Detail Information

Publications46

  1. doi request reprint Effects of persistent Mal de debarquement syndrome on balance, psychological traits, and motor cortex exctiability
    Brian C Clark
    Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA
    J Clin Neurosci 20:446-50. 2013
    ..These findings help characterize MdDS, and provide insight into the physiology of MdDS...
  2. pmc What is dynapenia?
    Brian C Clark
    Ohio Musculoskeletal and Neurological Institute OMNI and Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
    Nutrition 28:495-503. 2012
    ..In addition, we address the role of nutrition in the muscular and neurologic systems for the preservation of muscle strength throughout the life span...
  3. ncbi request reprint The biology of manual therapies
    Brian C Clark
    Ohio University, OMNI and Department of Biomedical Sciences, 236 Irvine Hall, Athens, OH 45701, USA
    J Am Osteopath Assoc 112:617-29. 2012
    ..The authors have tested this hypothesis and summarize their work on the biology of manual therapies...
  4. pmc Age-related changes in motor cortical properties and voluntary activation of skeletal muscle
    Brian C Clark
    Ohio University, Department of Biomedical Sciences, Athens, OH 45701, USA
    Curr Aging Sci 4:192-9. 2011
    ..We also provide perspectives on scientific and clinical questions that need to be addressed in the near future...
  5. ncbi request reprint Effect of prolonged unweighting of human skeletal muscle on neuromotor force control
    Brian C Clark
    Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, 211 Irvine Hall, Athens, OH 45701, USA
    Eur J Appl Physiol 100:53-62. 2007
    ....
  6. doi request reprint Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with men
    Brian C Clark
    Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University, Athens, OH 45701, USA
    Arch Phys Med Rehabil 90:178-80. 2009
    ..To investigate sex-related differences in the loss and recovery of voluntary muscle strength after immobilization...
  7. doi request reprint Immobilization-induced increase in fatigue resistance is not explained by changes in the muscle metaboreflex
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, 211 Irvine Hall, Ohio University, Athens, Ohio 45701, USA
    Muscle Nerve 38:1466-73. 2008
    ..05). These findings indicate that the augmentation of time to task failure with immobilization is not associated with changes in the pressor or metaboreflex responses...
  8. ncbi request reprint Sarcopenia =/= dynapenia
    Brian C Clark
    Department of Biomedical Sciences, Ohio University, 211 Irvine Hall, Athens, OH 45701, USA
    J Gerontol A Biol Sci Med Sci 63:829-34. 2008
    ..Rather, we propose that alternative mechanisms underlie dynapenia (i.e., alterations in contractile properties or neurologic function), and urge that greater attention be paid to these variables in determining their role in dynapenia...
  9. pmc Cast immobilization increases long-interval intracortical inhibition
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA
    Muscle Nerve 42:363-72. 2010
    ..63). The H-reflex increased following immobilization. These findings suggest that immobilization increases intracortical inhibition during contraction, and this increase is primarily mediated by GABA(B) receptors...
  10. doi request reprint Neuromuscular plasticity during and following 3 wk of human forearm cast immobilization
    Brian C Clark
    Dept of Biomedical Sciences, Ohio Univ College of Osteopathic Medicine, Athens, OH 45701, USA
    J Appl Physiol (1985) 105:868-78. 2008
    ....
  11. pmc Neurophysiologic effects of spinal manipulation in patients with chronic low back pain
    Brian C Clark
    Ohio Musculoskeletal and Neurological Institute OMNI, Ohio University, 236 Irvine Hall, Athens, OH 45701, USA
    BMC Musculoskelet Disord 12:170. 2011
    ....
  12. doi request reprint In vivo alterations in skeletal muscle form and function after disuse atrophy
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, OH 45701, USA
    Med Sci Sports Exerc 41:1869-75. 2009
    ..Lastly, emerging data warranting further inquiry into the modulating role of biological sex on disuse-induced adaptations are also discussed...
  13. doi request reprint Relative safety of 4 weeks of blood flow-restricted resistance exercise in young, healthy adults
    B C Clark
    Department of Biomedical Sciences, Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA
    Scand J Med Sci Sports 21:653-62. 2011
    ....
  14. pmc Muscle functional magnetic resonance imaging and acute low back pain: a pilot study to characterize lumbar muscle activity asymmetries and examine the effects of osteopathic manipulative treatment
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Ohio University College of Osteopathic Medicine, Northfield, OH, USA
    Osteopath Med Prim Care 3:7. 2009
    ....
  15. doi request reprint Men and women exhibit a similar time to task failure for a sustained, submaximal elbow extensor contraction
    Douglas J Dearth
    Institute for Neuromusculoskeletal Research, Ohio University, Athens, OH, USA
    Eur J Appl Physiol 108:1089-98. 2010
    ....
  16. pmc Older adults exhibit more intracortical inhibition and less intracortical facilitation than young adults
    Marisa McGinley
    Institute for Neuromusculoskeletal Research, Ohio University, United States Department of Biomedical Sciences, Ohio University, United States
    Exp Gerontol 45:671-8. 2010
    ..Aging results in decreased neuromuscular function, which is likely associated with neurologic alterations. At present little is known regarding age-related changes in intracortical properties...
  17. pmc Interrelationship between muscle strength, motor units, and aging
    Ryan D Kaya
    Ohio Musculoskeletal and Neurological Institute OMNI, Athens, OH, USA
    Exp Gerontol 48:920-5. 2013
    ..18). These findings indicate that there is an interrelationship between muscle strength, MU numbers, and aging, which suggests that a portion of muscle weakness in seniors may be attributable to the loss of functioning motor units...
  18. doi request reprint Delayed-onset muscle soreness induced by low-load blood flow-restricted exercise
    Jonathan D Umbel
    Institute for Neuromusculoskeletal Research, Ohio University, Athens, OH, USA
    Eur J Appl Physiol 107:687-95. 2009
    ..7% decrease vs. 3.4 +/- 2.5% decrease) (p <or= 0.05). These data suggest that knee extension BFR exercise induces mild DOMS and that BFR exercise elicits muscle damage under atypical conditions with low-tension concentric contractions...
  19. doi request reprint Non-thrust manual therapy reduces erector spinae short-latency stretch reflex asymmetries in patients with chronic low back pain
    David A Goss
    Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH 45701, USA
    J Electromyogr Kinesiol 22:663-9. 2012
    ..Ultimately, developing a better understanding of the physiologic effects of manual therapies will assist in optimizing treatment strategies for patients with LBP...
  20. doi request reprint Time to task failure of trunk extensor muscles differs with load type
    James S Thomas
    School of Rehabilitation and Communication Sciences, Division of Physical Therapy, Ohio University, Athens 45701, USA
    J Mot Behav 43:27-9. 2011
    ..This could be an important issue in understanding the mechanisms of task failure, and the endurance capacity of the trunk extensor muscles...
  21. ncbi request reprint Fatigue-induced changes in phasic muscle activation patterns during dynamic trunk extension exercise
    Brian C Clark
    Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, Ohio 45701, USA
    Am J Phys Med Rehabil 86:373-9. 2007
    ..To investigate the influence of fatigue on phasic muscle-activation patterns during dynamic trunk extension exercise...
  22. doi request reprint Novel methods for quantifying neurophysiologic properties of the human lumbar paraspinal muscles
    David A Goss
    Institute for Neuromusculoskeletal Research, Ohio University, United States
    J Neurosci Methods 194:329-35. 2011
    ..05). These innovative methods may be useful in studying basic physiology, the pathology of low back pain, as well as the mechanisms of action of treatment interventions...
  23. doi request reprint Development of a neuromuscular electrical stimulation protocol for sprint training
    David W Russ
    Laboratory for Integrative Muscle Biology, Division of Physical Therapy, Ohio University, School of Rehabilitation and Communication Sciences, Athens, OH 45701, USA
    Med Sci Sports Exerc 44:1810-9. 2012
    ..The purpose of this report was to describe the development of a tolerable neuromuscular electrical stimulation (NMES) protocol that induces skeletal muscle adaptations similar to those observed with sprint training...
  24. pmc Functional consequences of sarcopenia and dynapenia in the elderly
    Brian C Clark
    Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
    Curr Opin Clin Nutr Metab Care 13:271-6. 2010
    ....
  25. ncbi request reprint Cortical and spinal mechanisms of task failure of sustained submaximal fatiguing contractions
    Petra S Williams
    Ohio Musculoskeletal and Neurological Institute OMNI, Ohio University, Athens, Ohio, United States of America Department of Physical Therapy and Athletic Training, Northern Arizona University, Flagstaff, Arizona, United States of America
    PLoS ONE 9:e93284. 2014
    ....
  26. doi request reprint Reliability of a modified motor unit number index (MUNIX) technique
    Ryan D Kaya
    Ohio Musculoskeletal and Neurological Institute OMNI at Ohio University, Athens, OH, United States School of Applied Health Sciences and Wellness at Ohio University, Athens, OH, United States
    J Electromyogr Kinesiol 24:18-24. 2014
    ..The purpose of this study was to examine the relative and absolute between-day reliability of the motor unit number index (MUNIX)...
  27. doi request reprint Social, societal, and economic burden of mal de debarquement syndrome
    Allison Macke
    Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH 45701, USA
    J Neurol 259:1326-30. 2012
    ..MdDS negatively and dramatically impacts QOL, and also imposes a substantial economic burden on MdDS patients. These findings underscore the need for further basic and clinical research on MdDS...
  28. pmc Preliminary evidence that anodal transcranial direct current stimulation enhances time to task failure of a sustained submaximal contraction
    Petra S Williams
    Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, Ohio, United States of America Department of Physical Therapy and Athletic Training, Northern Arizona University, Flagstaff, Arizona, United States of America
    PLoS ONE 8:e81418. 2013
    ..The results also suggest that the application of tDCS during performance of fatiguing activity has the potential to bolster the capacity to exercise under conditions required to derive benefits due to overload. ..
  29. pmc Aging and muscle: a neuron's perspective
    Todd M Manini
    Institute of Aging and the Department of Aging and Geriatric Research, University of Florida, Gainesville, Florida 32611, USA
    Curr Opin Clin Nutr Metab Care 16:21-6. 2013
    ..Here, we briefly discuss age-related impairments in the brain and peripheral nerve structures that may theoretically lead to muscle weakness in old age...
  30. pmc Evolving concepts on the age-related changes in "muscle quality"
    David W Russ
    Ohio Musculoskeletal and Neurological Institute OMNI, Ohio University, 236 Irvine Hall, Athens, OH, 45701, USA
    J Cachexia Sarcopenia Muscle 3:95-109. 2012
    ....
  31. ncbi request reprint Growth hormone and muscle function responses to skeletal muscle ischemia
    Joseph R Pierce
    Department of Exercise Science, Syracuse University, Syracuse, New York, USA
    J Appl Physiol 101:1588-95. 2006
    ..In conclusion, ISC coupled with resistance exercise acutely increases GH levels and reduces MVC, whereas ISC alone decreases force capacity, without alterations in GH levels...
  32. ncbi request reprint Electromyographic activity of the lumbar and hip extensors during dynamic trunk extension exercise
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, 820 Comstock Avenue, Room 201, Syracuse, NY 13244, USA
    Arch Phys Med Rehabil 83:1547-52. 2002
    ..To evaluate the effects of exercise intensity and multiple sets on muscle activation patterns during trunk extension exercise...
  33. ncbi request reprint Gender differences in skeletal muscle fatigability are related to contraction type and EMG spectral compression
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse 13244, USA
    J Appl Physiol (1985) 94:2263-72. 2003
    ..45 vs. 0.19). These findings suggest that gender differences in muscle fatigue are influenced by muscle contraction type and frequency shifts in the EMG signal but not by alterations in the synergistic activation patterns...
  34. ncbi request reprint Leg muscle activity during walking with assistive devices at varying levels of weight bearing
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
    Arch Phys Med Rehabil 85:1555-60. 2004
    ..To evaluate the muscle activation patterns at varying levels of weight-bearing forces during assisted walking with an axillary crutch and a recently designed device that allows weight transfer through the pelvic girdle (ED Walker)...
  35. ncbi request reprint Derecruitment of the lumbar musculature with fatiguing trunk extension exercise
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse, New York 13244, USA
    Spine (Phila Pa 1976) 28:282-7. 2003
    ..This was a descriptive study involving 20 healthy individuals...
  36. ncbi request reprint Sex differences in muscle fatigability and activation patterns of the human quadriceps femoris
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
    Eur J Appl Physiol 94:196-206. 2005
    ....
  37. doi request reprint Quantification of the corticospinal silent period evoked via transcranial magnetic stimulation
    Leatha A Damron
    Department of Physical Therapy, SUNY Upstate Medical University, United States
    J Neurosci Methods 173:121-8. 2008
    ..These results suggest that SPs evoked with a stimulus intensity >or=30% AMT and quantified visually by defining the start of the SP at stimulus delivery or the start of the MEP be utilized to decrease the between visit variability...
  38. ncbi request reprint Reliability of techniques to assess human neuromuscular function in vivo
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, 820 Comstock Avenue, Room 201, Syracuse, NY 13244, USA
    J Electromyogr Kinesiol 17:90-101. 2007
    ..In conclusion, while the reliability differed between the various measures, in general it was rather high even when the testing sessions are separated by a relatively long duration of time...
  39. ncbi request reprint Adaptations in human neuromuscular function following prolonged unweighting: II. Neurological properties and motor imagery efficacy
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, New York, USA
    J Appl Physiol (1985) 101:264-72. 2006
    ....
  40. ncbi request reprint Adaptations in human neuromuscular function following prolonged unweighting: I. Skeletal muscle contractile properties and applied ischemia efficacy
    Brian C Clark
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, New York, USA
    J Appl Physiol (1985) 101:256-63. 2006
    ..These findings suggest that unweighting alters the contractile properties involved in the excitation-contraction coupling processes and that Isc impacts the sarcolemma...
  41. doi request reprint Kinesthetic motor imagery and spinal excitability: the effect of contraction intensity and spatial localization
    Patrick M Cowley
    Musculoskeletal Research Laboratory, Department of Exercise Science at Syracuse University, 201 Women s Building, 820 Comstock Ave, Syracuse, NY 13244, USA
    Clin Neurophysiol 119:1849-56. 2008
    ..Our research questions required two experiments...
  42. ncbi request reprint Effects of exercise load and blood-flow restriction on skeletal muscle function
    Summer B Cook
    Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244 5040, USA
    Med Sci Sports Exerc 39:1708-13. 2007
    ..It is unclear how occlusion pressure, exercise intensity, and occlusion duration interact, or which combination of these factors results in the most potent muscle stimulus...
  43. ncbi request reprint Reduced physical activity increases intermuscular adipose tissue in healthy young adults
    Todd M Manini
    Department of Aging and Geriatrics, Institute on Aging, University of Florida, Gainesville, FL 32611 0107, USA
    Am J Clin Nutr 85:377-84. 2007
    ..Although several studies have described adaptations in muscle after reduced physical activity, the change in IMAT in healthy young adults is unknown...
  44. ncbi request reprint Evaluation of spastic muscle in stroke survivors using magnetic resonance imaging and resistance to passive motion
    Lori L Ploutz-Snyder
    Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA
    Arch Phys Med Rehabil 87:1636-42. 2006
    ..To assess the feasibility of using magnetic resonance imaging (MRI) and resistance to passive movement to evaluate spastic muscle...
  45. ncbi request reprint Resistance and functional training reduces knee extensor position fluctuations in functionally limited older adults
    Todd M Manini
    Musculoskeletal Research Laboratory, Syracuse University, Syracuse, NY, USA
    Eur J Appl Physiol 95:436-46. 2005
    ....
  46. ncbi request reprint The use of magnetic resonance imaging to evaluate lumbar muscle activity during trunk extension exercise at varying intensities
    John M Mayer
    Department of Exercise Science, Syracuse University, Syracuse, New York, USA
    Spine (Phila Pa 1976) 30:2556-63. 2005
    ..Descriptive, repeated measures analysis of exercise-induced changes in lumbar muscle transverse relaxation time (T2)...