Huzoor Akbar

Summary

Affiliation: Ohio University
Country: USA

Publications

  1. pmc Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation
    Huzoor Akbar
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio, United States of America
    PLoS ONE 6:e22117. 2011
  2. pmc A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulin
    Rehana Perveen
    Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, United States of America
    PLoS ONE 6:e26238. 2011
  3. doi request reprint A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo
    Yi Liu
    Department of Biological Science, Ohio University, Athens, OH, USA
    Mol Cancer Ther 11:1672-82. 2012

Collaborators

  • Shiyong Wu
  • Yi Liu
  • Xiaozhuo Chen
  • Yanyan Cao
  • Rehana Perveen
  • STEPHEN BERGMEIER
  • Weihe Zhang
  • Robert Colvin
  • Juan Ding
  • Lingying Tong
  • Jennifer Hines
  • Yanrong Qian
  • Shelli Wulf Ridge
  • Jean Thuma
  • Kevin Funk
  • Jan Willem N Akkerman

Detail Information

Publications3

  1. pmc Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation
    Huzoor Akbar
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio, United States of America
    PLoS ONE 6:e22117. 2011
    ..However, the role of Cdc42 in platelet activation remains controversial. This study was undertaken to better understand the role of Cdc42 in platelet activation...
  2. pmc A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulin
    Rehana Perveen
    Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, United States of America
    PLoS ONE 6:e26238. 2011
    ..In this study we tested our hypothesis that if insulin possesses anti-platelet properties then insulin mimetic small molecules should mimic antiplatelet actions of insulin...
  3. doi request reprint A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo
    Yi Liu
    Department of Biological Science, Ohio University, Athens, OH, USA
    Mol Cancer Ther 11:1672-82. 2012
    ..Thus, WZB117 is a prototype for further development of anticancer therapeutics targeting Glut1-mediated glucose transport and glucose metabolism...