Carol L Shields

Summary

Affiliation: Ocular Oncology Service
Country: USA

Publications

  1. doi request reprint Massive macronodular juvenile xanthogranuloma of the eyelid in a newborn
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Electronic address
    J AAPOS 18:195-7. 2014
  2. doi request reprint Ciliary body and choroidal pseudomelanoma from ultrasonographic imaging of hypermature cataract in 20 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Electronic address
    Ophthalmology 120:2546-51. 2013
  3. doi request reprint Association of ocular and oculodermal melanocytosis with the rate of uveal melanoma metastasis: analysis of 7872 consecutive eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    JAMA Ophthalmol 131:993-1003. 2013
  4. doi request reprint American Joint Committee on Cancer classification of posterior uveal melanoma (tumor size category) predicts prognosis in 7731 patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Dr Kaliki is in practice at the Ocular Oncology Service, L V Prasad Eye Institute, Hyderabad, India Electronic address
    Ophthalmology 120:2066-71. 2013
  5. doi request reprint Giant conjunctival nevus: clinical features and natural course in 32 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    JAMA Ophthalmol 131:857-63. 2013
  6. doi request reprint Iris nevus growth into melanoma: analysis of 1611 consecutive eyes: the ABCDEF guide
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:766-72. 2013
  7. pmc Retinoblastoma frontiers with intravenous, intra-arterial, periocular, and intravitreal chemotherapy
    C L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Eye (Lond) 27:253-64. 2013
  8. doi request reprint Lesions simulating retinoblastoma (pseudoretinoblastoma) in 604 cases: results based on age at presentation
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:311-6. 2013
  9. doi request reprint Iris melanoma management with iodine-125 plaque radiotherapy in 144 patients: impact of melanoma-related glaucoma on outcomes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:55-61. 2013
  10. doi request reprint American Joint Committee on Cancer (AJCC) clinical classification predicts conjunctival melanoma outcomes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthal Plast Reconstr Surg 28:313-23. 2012

Detail Information

Publications133 found, 100 shown here

  1. doi request reprint Massive macronodular juvenile xanthogranuloma of the eyelid in a newborn
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Electronic address
    J AAPOS 18:195-7. 2014
    ..The mass showed positive immunoreactivity, with histiocytic markers CD163 and factor XIII, and was negative for cytokeratin markers, smooth muscle actin, and desmin. These features were compatible with JXG. ..
  2. doi request reprint Ciliary body and choroidal pseudomelanoma from ultrasonographic imaging of hypermature cataract in 20 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Electronic address
    Ophthalmology 120:2546-51. 2013
    ..To describe a series of 20 patients with opaque media, referred with uveal melanoma, but subsequently found to have pseudomelanoma from oblique imaging of hypermature cataract on ultrasonography...
  3. doi request reprint Association of ocular and oculodermal melanocytosis with the rate of uveal melanoma metastasis: analysis of 7872 consecutive eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    JAMA Ophthalmol 131:993-1003. 2013
    ..In this study, patients with melanocytosis who developed uveal melanoma were found to have double the risk for metastasis compared with those without melanocytosis...
  4. doi request reprint American Joint Committee on Cancer classification of posterior uveal melanoma (tumor size category) predicts prognosis in 7731 patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania Dr Kaliki is in practice at the Ocular Oncology Service, L V Prasad Eye Institute, Hyderabad, India Electronic address
    Ophthalmology 120:2066-71. 2013
    ..To evaluate the clinical features and prognosis of posterior uveal (ciliary body and choroid) melanoma based on the American Joint Committee on Cancer (AJCC) classification (7th edition) of primary tumorĀ (T)...
  5. doi request reprint Giant conjunctival nevus: clinical features and natural course in 32 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    JAMA Ophthalmol 131:857-63. 2013
    ..Conjunctival nevus is the most common tumor of the ocular surface and we selected the largest nevi to evaluate for clinical features and outcomes...
  6. doi request reprint Iris nevus growth into melanoma: analysis of 1611 consecutive eyes: the ABCDEF guide
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:766-72. 2013
    ..To determine clinical features predictive of growth of iris nevus into melanoma...
  7. pmc Retinoblastoma frontiers with intravenous, intra-arterial, periocular, and intravitreal chemotherapy
    C L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Eye (Lond) 27:253-64. 2013
    ..Bilateral retinoblastoma is most often managed with IVC and unilateral retinoblastoma with IAC, but if advanced stage, combination IVC plus IAC or enucleation...
  8. doi request reprint Lesions simulating retinoblastoma (pseudoretinoblastoma) in 604 cases: results based on age at presentation
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:311-6. 2013
    ..To determine the types and frequency of ocular conditions that simulate retinoblastoma (pseudoretinoblastoma) based on age at presentation...
  9. doi request reprint Iris melanoma management with iodine-125 plaque radiotherapy in 144 patients: impact of melanoma-related glaucoma on outcomes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 120:55-61. 2013
    ..To evaluate the outcomes of iris melanoma managed with plaque radiotherapy on the basis of the initial presence or absence of glaucoma...
  10. doi request reprint American Joint Committee on Cancer (AJCC) clinical classification predicts conjunctival melanoma outcomes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthal Plast Reconstr Surg 28:313-23. 2012
    ..The aim of this study was to evaluate conjunctival melanoma outcomes based on American Joint Committee on Cancer classification. The study design constituted a nonrandomized interventional case series...
  11. doi request reprint Enhanced depth imaging optical coherence tomography of small choroidal melanoma: comparison with choroidal nevus
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Arch Ophthalmol 130:850-6. 2012
    ..To evaluate characteristics of small choroidal melanoma using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT)...
  12. doi request reprint Clinical spectrum and prognosis of uveal melanoma based on age at presentation in 8,033 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA
    Retina 32:1363-72. 2012
    ..To evaluate clinical features and life prognosis of uveal melanoma based on age at presentation...
  13. doi request reprint Epibulbar osseous choristoma in 8 patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA
    Cornea 31:756-60. 2012
    ..To describe the clinical features and histopathology of epibulbar osseous choristoma in a series of patients...
  14. doi request reprint Fluorescein angiographic findings after intra-arterial chemotherapy for retinoblastoma
    Carlos Bianciotto
    Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA
    Ophthalmology 119:843-9. 2012
    ..To evaluate fluorescein angiography (FA) findings after intra-arterial chemotherapy (IAC) for retinoblastoma...
  15. doi request reprint Effect of intraarterial chemotherapy on retinoblastoma-induced retinal detachment
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA, USA
    Retina 32:799-804. 2012
    ..To study the effect of intraarterial chemotherapy (IAC) on retinoblastoma-induced retinal detachment...
  16. doi request reprint Iris melanoma: features and prognosis in 317 children and adults
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J AAPOS 16:10-6. 2012
    ..To evaluate iris melanoma in children versus adults...
  17. doi request reprint Clinical survey of 3680 iris tumors based on patient age at presentation
    Carol L Shields
    Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA
    Ophthalmology 119:407-14. 2012
    ..To report the spectrum of iris lesions based on patient age at presentation...
  18. doi request reprint Topical interferon alfa-2b for management of ocular surface squamous neoplasia in 23 cases: outcomes based on American Joint Committee on Cancer classification
    Sanket U Shah
    The Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Arch Ophthalmol 130:159-64. 2012
    ..To evaluate the efficacy of topical interferon alfa-2b in the management of ocular surface squamous neoplasia (OSSN)...
  19. doi request reprint Bevacizumab for Coats' disease with exudative retinal detachment and risk of vitreoretinal traction
    Aparna Ramasubramanian
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Br J Ophthalmol 96:356-9. 2012
    ..To evaluate the effect of supplemental intravitreal bevacizumab for management of Coats' disease...
  20. doi request reprint Minimal exposure (one or two cycles) of intra-arterial chemotherapy in the management of retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA 19107, USA
    Ophthalmology 119:188-92. 2012
    ..To assess the efficacy of less than 3 cycles of intra-arterial chemotherapy (IAC) for retinoblastoma...
  21. ncbi request reprint Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 114:e53-8. 2007
    ..To evaluate the retinal status overlying choroidal osteoma using optical coherence tomography (OCT)...
  22. ncbi request reprint Conjunctival tumors in children
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Curr Opin Ophthalmol 18:351-60. 2007
    ..Numerous conjunctival tumors can occur in children, originating from tissues of choristomatous, epithelial, melanocytic, vascular, fibrous, xanthomatous and lymphoid. Overall, 97% prove to be benign and only 3% are malignant...
  23. doi request reprint Regression of uveal melanoma after plaque radiotherapy and thermotherapy based on chromosome 3 status
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA
    Retina 28:1289-95. 2008
    ..To evaluate regression rates after plaque radiotherapy and thermotherapy of uveal melanoma with chromosome 3 monosomy versus disomy...
  24. doi request reprint Autofluorescence of choroidal nevus in 64 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Retina 28:1035-43. 2008
    ..To describe the autofluorescence features of choroidal nevi...
  25. doi request reprint Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmology 115:2253-8. 2008
    ..To evaluate the clinical features and management of diffuse infiltrating retinoblastoma...
  26. doi request reprint Combined hamartoma of the retina and retinal pigment epithelium in 77 consecutive patients visual outcome based on macular versus extramacular tumor location
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmology 115:2246-2252.e3. 2008
    ..To evaluate visual outcome of eyes with combined hamartoma of the retina and retinal pigment epithelium (RPE)...
  27. doi request reprint Ocular melanoma: relatively rare but requiring respect
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA 19107, USA
    Clin Dermatol 27:122-33. 2009
    ..Eyelid and primary orbital melanoma are the least common variants. Early diagnosis from annual ocular examination by an experienced ophthalmologist and treatment strategies are reviewed...
  28. doi request reprint Autofluorescence of choroidal melanoma in 51 cases
    C L Shields
    Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA
    Br J Ophthalmol 92:617-22. 2008
    ..To describe the autofluorescence features of choroidal melanoma...
  29. doi request reprint The hunt for the secrets of uveal melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Clin Experiment Ophthalmol 36:277-80. 2008
    ..Currently, the most important mutation proves to be chromosome 3 monosomy, an abnormality associated with greater risk for metastatic disease...
  30. doi request reprint Pigmented squamous cell carcinoma in situ of the conjunctiva in 5 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 115:1673-8. 2008
    ..To describe 5 patients with pigmented conjunctival squamous cell carcinoma in situ...
  31. doi request reprint Resolution of exudative retinal detachment from retinal astrocytoma following photodynamic therapy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Ste 1440, 840 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 126:273-4. 2008
  32. ncbi request reprint Macular retinoblastoma managed with chemoreduction: analysis of tumor control with or without adjuvant thermotherapy in 68 tumors
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA
    Arch Ophthalmol 123:765-73. 2005
    ..To evaluate the effectiveness of chemoreduction alone and chemoreduction with thermotherapy for macular retinoblastoma...
  33. ncbi request reprint Clinical spectrum of choroidal nevi based on age at presentation in 3422 consecutive eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 115:546-552.e2. 2008
    ..To evaluate the clinical features of choroidal nevi based on patient age at presentation and to investigate features of the nevi that are predictive of patient symptoms...
  34. ncbi request reprint Autofluorescence of orange pigment overlying small choroidal melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Retina 27:1107-11. 2007
    ..To describe the autofluorescence features of orange pigment (intracellular lipofuscin) overlying small presumed choroidal melanomas...
  35. ncbi request reprint Autofluorescence of congenital hypertrophy of the retinal pigment epithelium
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Retina 27:1097-100. 2007
    ..To describe the autofluorescence features of CHRPE...
  36. ncbi request reprint Visual acuity in 3422 consecutive eyes with choroidal nevus
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, 840 Walnut St, Ste 1440, Philadelphia, PA 19107, USA
    Arch Ophthalmol 125:1501-7. 2007
    ..To evaluate visual acuity in eyes with choroidal nevus...
  37. doi request reprint Chemoreduction for group E retinoblastoma: comparison of chemoreduction alone versus chemoreduction plus low-dose external radiotherapy in 76 eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 116:544-551.e1. 2009
    ..To evaluate chemoreduction (CRD) for group E retinoblastoma...
  38. doi request reprint Peripheral exudative hemorrhagic chorioretinopathy simulating choroidal melanoma in 173 eyes
    Carol L Shields
    The Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 116:529-35. 2009
    ..To evaluate the clinical features and outcomes of eyes with peripheral exudative hemorrhagic chorioretinopathy (PEHCR) simulating choroidal melanoma...
  39. doi request reprint Retinoblastoma regression patterns following chemoreduction and adjuvant therapy in 557 tumors
    Carol L Shields
    The Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, 840 Walnut St, Ste 1440, Philadelphia, Pennsylvania 19107, USA
    Arch Ophthalmol 127:282-90. 2009
    ..To evaluate retinoblastoma regression patterns following chemoreduction and adjuvant therapy...
  40. doi request reprint Postenucleation adjuvant chemotherapy with vincristine, etoposide, and carboplatin for the treatment of high-risk retinoblastoma
    Swathi Kaliki
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA 19107, USA
    Arch Ophthalmol 129:1422-7. 2011
    ....
  41. doi request reprint Sector (partial) oculo(dermal) melanocytosis in 89 eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 118:2474-9. 2011
    ..To describe sector (partial) involvement of the uvea with melanocytosis...
  42. doi request reprint Phacomatosis pigmentovascularis of cesioflammea type in 7 patients: combination of ocular pigmentation (melanocytosis or melanosis) and nevus flammeus with risk for melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 129:746-50. 2011
    ..To describe the features of phacomatosis pigmentovascularis (cesioflammea type)...
  43. doi request reprint Intra-arterial chemotherapy for retinoblastoma: report No. 1, control of retinal tumors, subretinal seeds, and vitreous seeds
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA 19107, USA
    Arch Ophthalmol 129:1399-406. 2011
    ..To describe tumor control following intra-arterial chemotherapy (IAC) for retinoblastoma...
  44. doi request reprint Intra-arterial chemotherapy for retinoblastoma: report No. 2, treatment complications
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, PA 19107, USA
    Arch Ophthalmol 129:1407-15. 2011
    ..To describe treatment complications following intra-arterial chemotherapy (IAC) for retinoblastoma...
  45. doi request reprint Iridocorneal endothelial syndrome masquerading as iris melanoma in 71 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 129:1023-9. 2011
    ..To describe the clinical features of iridocorneal endothelial (ICE) syndrome in a group of patients referred because of suspected iris melanoma...
  46. doi request reprint Cytogenetic testing of iris melanoma using fine needle aspiration biopsy in 17 patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Retina 31:574-80. 2011
    ..To determine the incidence of Chromosome 3 monosomy in iris melanoma using fine needle aspiration biopsy...
  47. doi request reprint Ocular surface squamous neoplasia (squamous cell carcinoma) of the socket: management of extensive tumors with interferon
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthal Plast Reconstr Surg 27:247-50. 2011
    ..To describe the clinical features and management of extensive ocular surface squamous neoplasia (OSSN) (squamous cell carcinoma) of the socket...
  48. doi request reprint Langerhans cell histiocytosis of the uvea with neovascular glaucoma: diagnosis by fine-needle aspiration biopsy and management with intraocular bevacizumab and brachytherapy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J AAPOS 14:534-7. 2010
    ..25 mg/0.05 mL) resolved the iris neovascularization, and plaque radiotherapy (brachytherapy) resolved the mass rapidly and completely, preserving the patient's visual acuity and preventing glaucoma during the 10-month follow-up...
  49. doi request reprint Anterior segment optical coherence tomography of conjunctival nevus
    Carol L Shields
    Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA
    Ophthalmology 118:915-9. 2011
    ..To evaluate conjunctival nevi using anterior segment optical coherence tomography (AS-OCT)...
  50. doi request reprint Intra-arterial chemotherapy for retinoblastoma: the beginning of a long journey
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA
    Clin Experiment Ophthalmol 38:638-43. 2010
    ..Despite its allure, intra-arterial chemotherapy should be used with caution, as in other fields of paediatric oncology it has been found to provide no advantage over intravenous chemotherapy. Time will tell...
  51. doi request reprint Retinoblastoma management: advances in enucleation, intravenous chemoreduction, and intra-arterial chemotherapy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, USA
    Curr Opin Ophthalmol 21:203-12. 2010
    ..To provide an update on current management of retinoblastoma..
  52. doi request reprint Choroidal vitiligo masquerading as large choroidal nevus: a report of four cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmology 117:109-113.e3. 2010
    ..To describe 4 patients with choroidal vitiligo masquerading as large choroidal nevus...
  53. doi request reprint Metastasis of uveal melanoma millimeter-by-millimeter in 8033 consecutive eyes
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, 840 Walnut St, Ste 1440, Philadelphia, PA 19107, USA
    Arch Ophthalmol 127:989-98. 2009
    ..To determine the rate of metastasis of uveal melanoma on the basis of tumor thickness in millimeters...
  54. doi request reprint Choroidal nevus transformation into melanoma: analysis of 2514 consecutive cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 127:981-7. 2009
    ..To determine features that are predictive of growth of choroidal nevi into melanoma...
  55. doi request reprint Halo nevus of the choroid in 150 patients: the 2010 Henry van Dyke Lecture
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA
    Arch Ophthalmol 128:859-64. 2010
    ..To evaluate choroidal halo nevus...
  56. ncbi request reprint Chromosome 3 analysis of uveal melanoma using fine-needle aspiration biopsy at the time of plaque radiotherapy in 140 consecutive cases: the Deborah Iverson, MD, Lectureship
    Carol L Shields
    Ocular Oncology Service, Suite 1440, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 125:1017-24. 2007
    ..To evaluate the feasibility of genetic testing of uveal melanoma using fine-needle aspiration biopsy (FNAB)...
  57. ncbi request reprint Diagnosis and management of retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas JeffersonUniversity, Philadelphia, PA 19107, USA
    Cancer Control 11:317-27. 2004
    ..Retinoblastoma is a highly malignant tumor of the eye that manifests most often in the first 3 years of life...
  58. ncbi request reprint Clinical features of small choroidal melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Curr Opin Ophthalmol 13:135-41. 2002
    ..Therefore, ophthalmologists should be aware of the important factors that identify small choroidal melanoma so that early treatment and better life prognosis can be achieved for their patients...
  59. ncbi request reprint Basic understanding of current classification and management of retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Curr Opin Ophthalmol 17:228-34. 2006
    ..The current classification and management strategies for retinoblastoma are discussed...
  60. ncbi request reprint Combined plaque radiotherapy and transpupillary thermotherapy for choroidal melanoma: tumor control and treatment complications in 270 consecutive patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 900 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 120:933-40. 2002
    ..To evaluate tumor control and treatment complications following plaque radiotherapy combined with transpupillary thermotherapy for choroidal melanoma...
  61. ncbi request reprint Chemoreduction for unilateral retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, 840 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 120:1653-8. 2002
    ..To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment...
  62. ncbi request reprint Optical coherence tomographic findings of combined hamartoma of the retina and retinal pigment epithelium in 11 patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, 840 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 123:1746-50. 2005
  63. ncbi request reprint Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107, USA
    Arch Ophthalmol 123:1658-66. 2005
    ..To evaluate choroidal osteoma for tumor growth, tumor decalcification, related choroidal neovascularization, visual acuity loss, and poor visual acuity...
  64. ncbi request reprint Restoration of foveal anatomy and function following chemoreduction for bilateral advanced retinoblastoma with total retinal detachment
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107, USA
    Arch Ophthalmol 123:1610-2. 2005
  65. ncbi request reprint Practical approach to management of retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA
    Arch Ophthalmol 122:729-35. 2004
    ..To present a simplified approach to management of retinoblastoma using basic clinical features...
  66. ncbi request reprint Development of new retinoblastomas after 6 cycles of chemoreduction for retinoblastoma in 162 eyes of 106 consecutive patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 121:1571-6. 2003
    ..To evaluate the occurrence of new retinoblastomas in patients treated with 6 cycles of chemoreduction...
  67. ncbi request reprint Chemoreduction for retinoblastoma may prevent intracranial neuroblastic malignancy (trilateral retinoblastoma)
    C L Shields
    Ocular Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107
    Arch Ophthalmol 119:1269-72. 2001
    ..To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral retinoblastoma)...
  68. ncbi request reprint Progressive enlargement of acquired retinal astrocytoma in 2 cases
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 111:363-8. 2004
    ..To document 2 cases of progressively enlarging retinal astrocytoma that caused exudative retinal detachment, vitreous hemorrhage, and tumor seeding, simulating retinoblastoma in 1 case and choroidal melanoma in the other...
  69. ncbi request reprint Recent developments in the management of choroidal melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, Pennsylvania, USA
    Curr Opin Ophthalmol 15:244-51. 2004
    ..To describe recent advances in the management of choroidal melanoma...
  70. ncbi request reprint Clinical factors in the identification of small choroidal melanoma
    Carol L Shields
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Can J Ophthalmol 39:351-7. 2004
    ..Therefore, ophthalmologists should be aware of the clinical factors that identify small choroidal melanoma so that early treatment and better prognosis can be achieved for their patients...
  71. ncbi request reprint Chemoreduction for retinoblastoma. Analysis of tumor control and risks for recurrence in 457 tumors
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA
    Am J Ophthalmol 138:329-37. 2004
    ..To evaluate retinoblastoma control following chemoreduction...
  72. ncbi request reprint Resolution of iris neovascularization following chemoreduction of advanced retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107, USA
    Arch Ophthalmol 124:1196-7. 2006
  73. doi request reprint Regression of extrafoveal choroidal osteoma following photodynamic therapy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107, USA
    Arch Ophthalmol 126:135-7. 2008
  74. ncbi request reprint Bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy: a report of three cases
    M Furuta
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Eur J Ophthalmol 16:879-82. 2006
    ..To report three cases of bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy...
  75. ncbi request reprint Small choroidal melanoma with chromosome 3 monosomy on fine-needle aspiration biopsy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 114:1919-24. 2007
    ..To evaluate the presence of chromosome 3 monosomy in small choroidal melanoma using fine-needle aspiration biopsy (FNAB)...
  76. ncbi request reprint Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy
    C L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 900 Walnut St, Philadelphia, PA 19107, USA
    Am J Ophthalmol 132:576-8. 2001
    ..To illustrate a novel method of management for extensive conjunctival and corneal melanoma...
  77. ncbi request reprint Neovascular glaucoma from advanced Coats disease as the initial manifestation of facioscapulohumeral dystrophy in a 2-year-old child
    Carol L Shields
    Ocular Oncology Service, Suite 1440, Wills Eye Hospital, 840 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 125:840-2. 2007
  78. ncbi request reprint Topical mitomycin C for extensive, recurrent conjunctival-corneal squamous cell carcinoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Am J Ophthalmol 133:601-6. 2002
    ..To evaluate the efficacy of topical mitomycin C for extensive recurrent conjunctival and corneal squamous cell carcinoma (SCC)...
  79. ncbi request reprint Sequential bilateral solitary extramedullary plasmacytoma of the ciliary body
    Carol L Shields
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cornea 26:759-61. 2007
    ..To report bilateral plasmacytoma of the ciliary body in a healthy patient...
  80. doi request reprint Plaque radiotherapy for juxtapapillary choroidal melanoma overhanging the optic disc in 141 consecutive patients
    Mandeep S Sagoo
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 126:1515-22. 2008
    ..To evaluate tumor control with plaque radiotherapy for juxtapapillary choroidal melanoma that overhangs the optic disc...
  81. ncbi request reprint Intravitreal triamcinolone acetonide for acute radiation papillopathy
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Retina 26:537-44. 2006
    ..To evaluate intravitreal triamcinolone acetonide for patients with visually symptomatic acute radiation-induced papillopathy...
  82. pmc Chemoreduction for retinoblastoma: analysis of tumor control and risks for recurrence in 457 tumors
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Trans Am Ophthalmol Soc 102:35-44; discussion 44-5. 2004
    ..To evaluate individual tumor control following chemoreduction for retinoblastoma...
  83. ncbi request reprint Chemoreduction plus focal therapy for retinoblastoma: factors predictive of need for treatment with external beam radiotherapy or enucleation
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Am J Ophthalmol 133:657-64. 2002
    ..To report the results of chemoreduction and focal therapy for retinoblastoma with determination of factors predictive of the need for treatment with external beam radiotherapy or enucleation...
  84. doi request reprint Early macular morphological changes following plaque radiotherapy for uveal melanoma
    Noel Horgan
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Retina 28:263-73. 2008
    ..To evaluate the time of onset and risk factors for the development of macular edema following plaque radiotherapy for uveal melanoma, using optical coherence tomography (OCT)...
  85. ncbi request reprint Conjunctival melanoma 3 years after radiation and chemotherapy for retinoblastoma
    Amita Mahajan
    Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Pediatr Ophthalmol Strabismus 44:300-2. 2007
    ..Excisional biopsy revealed an amelanotic melanoma of the conjunctiva with superficial orbital invasion. There has been no tumor recurrence during 20 months of follow-up...
  86. ncbi request reprint Iodine 125 plaque radiotherapy as salvage treatment for retinoblastoma recurrence after chemoreduction in 84 tumors
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 113:2087-92. 2006
    ..To assess tumor control and complications of iodine 125 (I125) plaque radiotherapy for retinoblastoma recurrence after chemoreduction (CRD)...
  87. ncbi request reprint Factors predictive of recurrence of retinal tumors, vitreous seeds, and subretinal seeds following chemoreduction for retinoblastoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 120:460-4. 2002
    ..To identify the clinical features of eyes with retinoblastomas that predict the recurrence of retinal tumors, vitreous seeds, and subretinal seeds following treatment with chemoreduction...
  88. doi request reprint Retinal break and rhegmatogenous retinal detachment after transpupillary thermotherapy as primary or adjunct treatment of choroidal melanoma
    Arman Mashayekhi
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Retina 28:274-81. 2008
    ..To report the development of retinal break or rhegmatogenous retinal detachment (RRD) after transpupillary thermotherapy (TTT) as primary or adjunct treatment of choroidal melanoma...
  89. ncbi request reprint Long-term visual outcome following chemoreduction for retinoblastoma
    Hakan Demirci
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 123:1525-30. 2005
    ..To evaluate long-term visual outcome following chemoreduction...
  90. doi request reprint Giant choroidal nevus clinical features and natural course in 322 cases
    Helen K Li
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 117:324-33. 2010
    ..Evaluation of clinical features and natural course of giant choroidal nevi (diameter >or=10 mm)...
  91. ncbi request reprint The International Classification of Retinoblastoma predicts chemoreduction success
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 113:2276-80. 2006
    ..To evaluate the reliability of the International Classification of Retinoblastoma (ICRB) for predicting treatment success with chemoreduction (CRD)...
  92. ncbi request reprint Histopathologic findings in eyes with retinoblastoma treated only with chemoreduction
    Hakan Demirci
    Oncology Service and the Department of Pathology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 121:1125-31. 2003
    ..To evaluate the histopathologic findings in the eyes with retinoblastoma that had been treated only with chemoreduction...
  93. ncbi request reprint Visual improvement in an adult amblyopic eye following radiation-induced visual loss in the contralateral eye
    Ekaterini C Karatza
    Oncology Service, Wills Eye Hospital, 840 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 122:126-8. 2004
  94. ncbi request reprint Two discrete choroidal melanomas in an eye with ocular melanocytosis
    Santosh G Honavar
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Surv Ophthalmol 47:36-41. 2002
    ..In conclusion, multifocal choroidal melanoma is rare and may be related to underlying ocular melanocytosis...
  95. ncbi request reprint Plaque radiotherapy for large posterior uveal melanomas (> or =8-mm thick) in 354 consecutive patients
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 109:1838-49. 2002
    ..To assess treatment complications and tumor control after plaque radiotherapy for large posterior uveal melanomas measuring 8 mm or greater in thickness...
  96. ncbi request reprint The histopathologic effects of transpupillary thermotherapy in human eyes
    Brian P Connolly
    Retina Service, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA
    Ophthalmology 110:415-20. 2003
    ..To determine the histopathologic effects of transpupillary thermotherapy (TTT) on the normal human retina...
  97. ncbi request reprint Custom-designed plaque radiotherapy for nonresectable iris melanoma in 38 patients: tumor control and ocular complications
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Am J Ophthalmol 135:648-56. 2003
    ..To evaluate plaque radiotherapy for iris melanoma...
  98. ncbi request reprint Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 109:225-34. 2002
    ..The objective of this report was to evaluate ocular and systemic outcomes after primary transpupillary thermotherapy for choroidal melanoma and to identify the limitations of this treatment method...
  99. doi request reprint Iridociliochoroidal melanoma arising from melanocytoma in a black teenager
    Helen K Li
    Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J AAPOS 14:178-80. 2010
    ..The eye was enucleated, and metastatic evaluation remained negative at 5 years' follow-up. This unusual case, confirmed histopathologically, reveals that young patients with melanocytoma can have malignant transformation at an early age...
  100. ncbi request reprint Intravitreal triamcinolone acetonide for radiation maculopathy after plaque radiotherapy for choroidal melanoma
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Retina 25:868-74. 2005
    ..To evaluate the effect of intravitreal triamcinolone acetonide on patients with visually symptomatic radiation-induced maculopathy after plaque radiotherapy for choroidal melanoma...
  101. doi request reprint Iodine I 125 plaque radiotherapy for vasoproliferative tumors of the retina in 30 eyes
    Victoria M L Cohen
    Ocular Oncology Service, Wills Eye Institute, Philadelphia, Pennsylvania, USA
    Arch Ophthalmol 126:1245-51. 2008
    ..To report the efficacy of iodine I 125 plaque radiotherapy for the treatment of vasoproliferative tumors (VPTs) of the ocular fundus...