Om Prakash

Summary

Affiliation: Ochsner Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice
    O Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, New Orleans, LA 70121, USA
    J Natl Cancer Inst 92:721-8. 2000
  2. ncbi request reprint Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 tat-expressing transgenic mice
    O Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, New Orleans, LA 70121, USA
    Alcohol Clin Exp Res 25:450-6. 2001
  3. ncbi request reprint Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line
    Om Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, 1516 Jefferson Highway, New Orleans, Louisiana 70121, USA
    Alcohol Clin Exp Res 26:295-302. 2002
  4. ncbi request reprint Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    J Natl Cancer Inst 94:926-35. 2002
  5. ncbi request reprint Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) infections in alcoholics
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Front Biosci 7:e286-300. 2002
  6. pmc Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, 1516 Jefferson Highway, New Orleans, LA 70121, USA
    Blood 105:3987-94. 2005
  7. pmc K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis
    Suizhao Wang
    Department of Lymphoma and Myeloma, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Blood 109:2174-82. 2007
  8. ncbi request reprint HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
    Hava Karsenty Avraham
    Division of Experimental Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115, USA
    J Immunol 173:6228-33. 2004
  9. ncbi request reprint Vascular endothelial growth factor and Kaposi's sarcoma cells in human skin grafts
    Felipe Samaniego
    Department of Lymphoma Myeloma, Clinical Cancer Prevention, Departments of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cell Growth Differ 13:387-95. 2002
  10. ncbi request reprint Acetohydroxamate inhibition of the activity of urease from dehusked seeds of water melon (Citrullus vulgaris)
    Om Prakash
    Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221005, India
    J Enzyme Inhib Med Chem 19:381-7. 2004

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice
    O Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, New Orleans, LA 70121, USA
    J Natl Cancer Inst 92:721-8. 2000
    ..To evaluate the growth-promoting effects of Tat in AIDS-KS in vivo, we developed transgenic mice expressing the one-exon-encoded 72 amino-acid protein (Tat(72)) and the two-exon-encoded 86 amino-acid protein (Tat(86))...
  2. ncbi request reprint Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 tat-expressing transgenic mice
    O Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, New Orleans, LA 70121, USA
    Alcohol Clin Exp Res 25:450-6. 2001
    ..Because there is evidence that viral transactivator Tat itself can induce hematopoietic suppression, in this study we examined the role of ethanol as a cofactor in transgenic mice that expressed HIV-1 Tat protein...
  3. ncbi request reprint Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line
    Om Prakash
    Laboratory of Molecular Oncology, Alton Ochsner Medical Foundation, 1516 Jefferson Highway, New Orleans, Louisiana 70121, USA
    Alcohol Clin Exp Res 26:295-302. 2002
    ..We examined the effect of ethanol and a combination of ethanol and AZT on TK and TMPK activities in human Jurkat T cells...
  4. ncbi request reprint Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    J Natl Cancer Inst 94:926-35. 2002
    ..To evaluate the potential role of K1 in HHV-8-associated pathogenesis, we produced transgenic mice expressing the HHV-8 K1 gene under the transcriptional control of the simian virus 40 promoter...
  5. ncbi request reprint Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) infections in alcoholics
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Front Biosci 7:e286-300. 2002
    ....
  6. pmc Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis
    Om Prakash
    Laboratory of Molecular Oncology, Ochsner Clinic Foundation, 1516 Jefferson Highway, New Orleans, LA 70121, USA
    Blood 105:3987-94. 2005
    ....
  7. pmc K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis
    Suizhao Wang
    Department of Lymphoma and Myeloma, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Blood 109:2174-82. 2007
    ..K1 may contribute to lymphoma development by stimulating cell survival by selectively blocking Fas-mediated apoptosis...
  8. ncbi request reprint HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
    Hava Karsenty Avraham
    Division of Experimental Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115, USA
    J Immunol 173:6228-33. 2004
    ..These studies define a mechanism for HIV-1 Tat in focal adhesion complex assembly in HBMECs via activation of FAK, leading to cytoskeletal reorganization and permeability changes...
  9. ncbi request reprint Vascular endothelial growth factor and Kaposi's sarcoma cells in human skin grafts
    Felipe Samaniego
    Department of Lymphoma Myeloma, Clinical Cancer Prevention, Departments of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cell Growth Differ 13:387-95. 2002
    ..KS cells inoculated with neutralizing anti-VEGF antibody did not form tumors. This study supports an important role for VEGF in tumor development and shows how a human tissue can preferentially promote tumor growth...
  10. ncbi request reprint Acetohydroxamate inhibition of the activity of urease from dehusked seeds of water melon (Citrullus vulgaris)
    Om Prakash
    Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221005, India
    J Enzyme Inhib Med Chem 19:381-7. 2004
    ..Pre-treatment of native enzyme with 8.0 mM ME for 5 min at 30 degrees C exhibited protection against AHA-induced inhibition. The significance of these observations is discussed...
  11. pmc Molecular cloning and characterization of three beta-defensins from canine testes
    Yongming Sang
    Department of Human Nutrition, 143B Justin Hall, Kansas State University, Manhattan, KS 66506 1407, USA
    Infect Immun 73:2611-20. 2005
    ..The tissue-specific expression and broad antimicrobial activity suggest that canine beta-defensins play an important role in host defense and other physiological functions of the male reproductive system...
  12. ncbi request reprint NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins
    W S Santhi
    Department of Molecular Medicine, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
    Exp Mol Pathol 81:123-30. 2006
    ..Our results thus point to NF-kappaB and COX-2 as participants in oral tumor progression and also to the validation of these two molecular markers in assessing minimal residual disease...
  13. pmc Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions
    Dingbo Lin
    Department of Biochemistry, Kansas State University, 141 Chalmers Hall, Manhattan, KS 66506, USA
    Exp Eye Res 85:113-22. 2007
    ..This can be prevented by a gap junction inhibitor. Thus, propagation of apoptosis from cell-to-cell in lens epithelial cells may be through open gap junctions. The control of gap junctions requires PKCgamma...