R Perrillo

Summary

Affiliation: Ochsner Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Multicenter study of lamivudine therapy for hepatitis B after liver transplantation. Lamivudine Transplant Group
    R Perrillo
    Section of Gastroenterology, Ochsner Clinic, New Orleans, LA 70121, USA
    Hepatology 29:1581-6. 1999
  2. ncbi request reprint Management of chronic hepatitis B virus infection: current perspectives for the nurse practitioner
    Robert Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    J Am Acad Nurse Pract 18:203-15. 2006
  3. ncbi request reprint Chronic hepatitis B: a critical appraisal of current approaches to therapy
    Robert P Perrillo
    Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Clin Gastroenterol Hepatol 4:233-48. 2006
  4. ncbi request reprint Therapy of hepatitis B -- viral suppression or eradication?
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Hepatology 43:S182-93. 2006
  5. ncbi request reprint Current treatment of chronic hepatitis B: benefits and limitations
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    Semin Liver Dis 25:20-8. 2005
  6. ncbi request reprint Overview of treatment of hepatitis B: key approaches and clinical challenges
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    Semin Liver Dis 24:23-9. 2004
  7. ncbi request reprint Comparison of quality of life, work productivity and medical resource utilization of peginterferon alpha 2a vs the combination of interferon alpha 2b plus ribavirin as initial treatment in patients with chronic hepatitis C
    R Perrillo
    Division on Gastroenterology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    J Viral Hepat 11:157-65. 2004
  8. ncbi request reprint Management of the patient with hepatitis B virus-related cirrhosis
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, Clinical Professor of Medicine, Tulane University School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    J Hepatol 39:S177-80. 2003
  9. ncbi request reprint Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus
    Robert Perrillo
    Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Gastroenterology 126:81-90. 2004
  10. ncbi request reprint Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants
    R Perrillo
    Ochsner Clinic, New Orleans, LA, USA
    Hepatology 32:129-34. 2000

Detail Information

Publications24

  1. ncbi request reprint Multicenter study of lamivudine therapy for hepatitis B after liver transplantation. Lamivudine Transplant Group
    R Perrillo
    Section of Gastroenterology, Ochsner Clinic, New Orleans, LA 70121, USA
    Hepatology 29:1581-6. 1999
    ..Repeat liver biopsies in 7 patients with the mutated virus were unchanged in 2, improved in 2, and worse in 3. We conclude that lamivudine is a potentially effective therapy for hepatitis B after liver transplantation...
  2. ncbi request reprint Management of chronic hepatitis B virus infection: current perspectives for the nurse practitioner
    Robert Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    J Am Acad Nurse Pract 18:203-15. 2006
    ..To address the clinical management of chronic hepatitis B virus (HBV) infection...
  3. ncbi request reprint Chronic hepatitis B: a critical appraisal of current approaches to therapy
    Robert P Perrillo
    Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Clin Gastroenterol Hepatol 4:233-48. 2006
    ..Expert opinions may differ from those of practicing hepatologists and gastroenterologists. We aimed to explore this issue further after a critical review of the literature...
  4. ncbi request reprint Therapy of hepatitis B -- viral suppression or eradication?
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Hepatology 43:S182-93. 2006
    ..I will present evidence in support of the recommendation that antiviral therapy should ideally be directed toward achieving the highest rate of viral clearance with the shortest interval of treatment...
  5. ncbi request reprint Current treatment of chronic hepatitis B: benefits and limitations
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    Semin Liver Dis 25:20-8. 2005
    ..The role for combination therapy remains unclear. Much has been accomplished over the past decade, but much remains to be done...
  6. ncbi request reprint Overview of treatment of hepatitis B: key approaches and clinical challenges
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    Semin Liver Dis 24:23-9. 2004
    ..From a theoretical perspective, a combination of pegylated interferon with one or more nucleosides could induce a higher rate of virological response. Additional studies are needed to further address these issues...
  7. ncbi request reprint Comparison of quality of life, work productivity and medical resource utilization of peginterferon alpha 2a vs the combination of interferon alpha 2b plus ribavirin as initial treatment in patients with chronic hepatitis C
    R Perrillo
    Division on Gastroenterology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    J Viral Hepat 11:157-65. 2004
    ..Patients randomized to pegIFNalpha 2a had improved work productivity, less activity impairment, decreased need for prescription drugs to treat adverse effects, and better adherence to therapy...
  8. ncbi request reprint Management of the patient with hepatitis B virus-related cirrhosis
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, Clinical Professor of Medicine, Tulane University School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    J Hepatol 39:S177-80. 2003
  9. ncbi request reprint Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus
    Robert Perrillo
    Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Gastroenterology 126:81-90. 2004
    ..We evaluated the efficacy and safety of adding adefovir dipivoxil to lamivudine in 135 patients with chronic hepatitis B (CHB) and YMDD mutant HBV...
  10. ncbi request reprint Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants
    R Perrillo
    Ochsner Clinic, New Orleans, LA, USA
    Hepatology 32:129-34. 2000
    ..This study provides evidence that adefovir dipivoxil can be an effective treatment for lamivudine-resistant HBV mutants as well as wild-type HBV...
  11. ncbi request reprint Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Hepatology 36:186-94. 2002
    ..Asians and Caucasians had similar rates of response to lamivudine at comparable ALT levels...
  12. ncbi request reprint How will we use the new antiviral agents for hepatitis B?
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70124, USA
    Curr Gastroenterol Rep 4:63-71. 2002
    ..From a theoretical perspective, the combination of interferon with one or more nucleoside analogues may be the most effective way to treat HBV infection in many clinical situations...
  13. ncbi request reprint Prevalence of HBV precore/core promoter variants in the United States
    Chi Jen Chu
    Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA
    Hepatology 38:619-28. 2003
    ..Physicians should be aware of the existence of HBV precore and core promoter variants and the clinical condition of "HBeAg-negative chronic hepatitis."..
  14. ncbi request reprint Customizing the management of chronic hepatitis B virus infection
    Robert G Gish
    Division of Hepatology and Complex GI, Physicians Foundation, California Pacific Medical Center, 2340 Clay Street, San Francisco, CA 94115, USA
    Semin Liver Dis 27:9-17. 2007
    ..The presentation highlighted recent findings suggesting that early, profound, and sustained viral suppression improves the probability of sustained virologic response and reduces the likelihood of nucleos(t)ide resistance...
  15. ncbi request reprint Halting the natural history of hepatitis B viral infection: a paradigm shift
    Robert P Perrillo
    Hepatology Division, Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 75246, USA
    Semin Liver Dis 27:3-8. 2007
    ..A satellite symposium conducted during the 57th Annual Meeting of the AASLD in Boston, Massachusetts, presented new findings relative to the course of HBV infection...
  16. ncbi request reprint Intramuscular hepatitis B immunoglobulin (HBIG) and nucleosides for prevention of recurrent hepatitis B following liver transplantation: comparison with other HBIG regimens
    Robert D Anderson
    Department of Medicine, Baylor Uinversity Medical Center and the Baylor Regional Transplant Institute, Dallas, TX, USA
    Clin Transplant 21:510-7. 2007
    ..Graft loss is usually avoidable when recurrence is discovered early and aggressively treated. The IM route is preferable to IV administration due to its ease of administration and lower cost...
  17. ncbi request reprint Comparison of clinical outcomes in chronic hepatitis B liver transplant candidates with and without hepatocellular carcinoma
    Stephen N Wong
    Division of Gastroenterology, University of Michigan, Ann Arbor, MI 48109 0362, USA
    Liver Transpl 13:334-42. 2007
    ..In conclusion, despite more advanced liver disease and a lower rate of transplantation, ITT survival of patients listed for HBV-cirrhosis was comparable to those with HBV-HCC, possibly related to beneficial effects of antiviral therapy...
  18. ncbi request reprint Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?
    Satheesh Nair
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation BH 309, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Hepatology 36:150-5. 2002
    ..However, as this study is based on patients with advanced cirrhosis, our findings need to be confirmed in a broader population of individuals with cirrhosis...
  19. ncbi request reprint The use of HBsAg-positive organ donors: far more than meets the eye?
    Robert P Perrillo
    Liver Transpl 11:875-7. 2005
  20. ncbi request reprint Determinants of early mortality in patients with decompensated chronic hepatitis B treated with antiviral therapy
    Robert J Fontana
    Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Gastroenterology 123:719-27. 2002
    ....
  21. ncbi request reprint Lamivudine and 24 weeks of lamivudine/interferon combination therapy for hepatitis B e antigen-positive chronic hepatitis B in interferon nonresponders
    Eugene R Schiff
    Division of Hepatology, University of Miami, Jackson Medical Towers, 1500 N W 12th Avenue, Suite 1101, Miami, FL 33136, USA
    J Hepatol 38:818-26. 2003
    ..We assessed lamivudine treatment, with or without added interferon, in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B who had failed interferon therapy previously...
  22. ncbi request reprint Hepatitis B virus genotypes in the United States: results of a nationwide study
    Chi Jen Chu
    Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Box 0362, Ann Arbor, Michigan 48109 0362, USA
    Gastroenterology 125:444-51. 2003
    ..The aims of this nationwide study were to determine the prevalence of HBV genotypes in the United States and the association between HBV genotypes and patient demographics, mode of infection, and clinical status...
  23. doi request reprint Lamivudine compared with lamivudine and adefovir dipivoxil for the treatment of HBeAg-positive chronic hepatitis B
    Joseph J Y Sung
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People s Republic of China
    J Hepatol 48:728-35. 2008
    ..We aimed to evaluate nucleoside/nucleotide combination therapy in treatment-naïve HBeAg-positive patients with chronic hepatitis B (CHB)...
  24. ncbi request reprint Hepatitis B and renal transplantation: securing the sword of damocles
    Robert P Perrillo
    Hepatology 36:1041-5. 2002