Tuan Vo-Dinh

Summary

Affiliation: Oak Ridge National Laboratory
Country: USA

Publications

  1. ncbi request reprint A hyperspectral imaging system for in vivo optical diagnostics. Hyperspectral imaging basic principles, instrumental systems, and applications of biomedical interest
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 6101, USA
    IEEE Eng Med Biol Mag 23:40-9. 2004
  2. ncbi request reprint Nanoprobes and nanobiosensors for monitoring and imaging individual living cells
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA
    Nanomedicine 2:22-30. 2006
  3. ncbi request reprint Fiber-optic nanosensors for single-cell monitoring
    Tuan Vo-Dinh
    Oak Ridge National Laboratory, Advanced Biomedical Science and Technology Group, Oak Ridge, TN 37831 6101, USA
    Anal Bioanal Chem 382:918-25. 2005
  4. ncbi request reprint Nanobiosensors: probing the sanctuary of individual living cells
    Tuan Vo-Dinh
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 6101, USA
    J Cell Biochem Suppl 39:154-61. 2002
  5. ncbi request reprint Development of a fluorescence detection system using optical parametric oscillator (OPO) laser excitation for in vivo diagnosis
    J M Song
    Oak Ridge National Laboratory, Bethel Valley Road, MS 6101, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Technol Cancer Res Treat 2:515-23. 2003
  6. ncbi request reprint Development of an advanced hyperspectral imaging (HSI) system with applications for cancer detection
    Matthew E Martin
    Center for Advanced Biomedical Phoronics, Life Sciences Division, Oak Ridge National Laboratory, Tennessee, 37831 6101, USA
    Ann Biomed Eng 34:1061-8. 2006
  7. ncbi request reprint Optical sensor for the detection of caspase-9 activity in a single cell
    Paul M Kasili
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    J Am Chem Soc 126:2799-806. 2004
  8. ncbi request reprint A compact CMOS biochip immunosensor towards the detection of a single bacteria
    Joon Myong Song
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, TN 37831 6101, USA
    Biosens Bioelectron 20:2203-9. 2005
  9. ncbi request reprint An AOTF-based dual-modality hyperspectral imaging system (DMHSI) capable of simultaneous fluorescence and reflectance imaging
    Matt E Martin
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 6101, USA
    Med Eng Phys 28:149-55. 2006
  10. ncbi request reprint Detection of cytochrome C in a single cell using an optical nanobiosensor
    Joon Myong Song
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Anal Chem 76:2591-4. 2004

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A hyperspectral imaging system for in vivo optical diagnostics. Hyperspectral imaging basic principles, instrumental systems, and applications of biomedical interest
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 6101, USA
    IEEE Eng Med Biol Mag 23:40-9. 2004
  2. ncbi request reprint Nanoprobes and nanobiosensors for monitoring and imaging individual living cells
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA
    Nanomedicine 2:22-30. 2006
    ..This article discusses the usefulness and potential of these nanotechnology-based systems in biological research and their applications to monitoring individual living cells...
  3. ncbi request reprint Fiber-optic nanosensors for single-cell monitoring
    Tuan Vo-Dinh
    Oak Ridge National Laboratory, Advanced Biomedical Science and Technology Group, Oak Ridge, TN 37831 6101, USA
    Anal Bioanal Chem 382:918-25. 2005
    ....
  4. ncbi request reprint Nanobiosensors: probing the sanctuary of individual living cells
    Tuan Vo-Dinh
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 6101, USA
    J Cell Biochem Suppl 39:154-61. 2002
    ..The usefulness and potential of this nanotechnology-based biosensor systems in biological research and applications in single-cell analysis are discussed...
  5. ncbi request reprint Development of a fluorescence detection system using optical parametric oscillator (OPO) laser excitation for in vivo diagnosis
    J M Song
    Oak Ridge National Laboratory, Bethel Valley Road, MS 6101, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Technol Cancer Res Treat 2:515-23. 2003
    ..Results reported herein demonstrate potential capabilities of the LIF-OPO system for in vivo disease diagnosis...
  6. ncbi request reprint Development of an advanced hyperspectral imaging (HSI) system with applications for cancer detection
    Matthew E Martin
    Center for Advanced Biomedical Phoronics, Life Sciences Division, Oak Ridge National Laboratory, Tennessee, 37831 6101, USA
    Ann Biomed Eng 34:1061-8. 2006
    ..It is shown that the instrument successfully distinguishes between normal and malignant mouse skin. It is hoped that the results of this study will lead to advances in the optical diagnosis of cancer in humans...
  7. ncbi request reprint Optical sensor for the detection of caspase-9 activity in a single cell
    Paul M Kasili
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    J Am Chem Soc 126:2799-806. 2004
    ..By comparing of the fluorescence signals from apoptotic cells induced by photodynamic treatment and nonapoptotic cells, we successfully detected caspase-9 activity, which indicates the onset of apoptosis in the cells...
  8. ncbi request reprint A compact CMOS biochip immunosensor towards the detection of a single bacteria
    Joon Myong Song
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, TN 37831 6101, USA
    Biosens Bioelectron 20:2203-9. 2005
    ..The results showed that the portable biochip system has great potential as a device for single-particle or possibly even single-organism detection...
  9. ncbi request reprint An AOTF-based dual-modality hyperspectral imaging system (DMHSI) capable of simultaneous fluorescence and reflectance imaging
    Matt E Martin
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 6101, USA
    Med Eng Phys 28:149-55. 2006
    ..The analysis also shows key spectroscopic differences between normal and malignant tissues. Further, these results are compared to real-time spectroscopic data and show good correlation...
  10. ncbi request reprint Detection of cytochrome C in a single cell using an optical nanobiosensor
    Joon Myong Song
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Anal Chem 76:2591-4. 2004
    ..Our results lead to the investigation of an apoptotic pathway at the single cell level...
  11. ncbi request reprint Optical nanobiosensor for monitoring an apoptotic signaling process in a single living cell following photodynamic therapy
    Paul M Kasili
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, TN 37831 6101, USA
    J Nanosci Nanotechnol 5:2057-62. 2005
    ..This work, in principle, demonstrates the minimally invasive capability of optical nanobiosensors to measure important signaling molecules and events in pathways at the single cell level...
  12. ncbi request reprint Surface-enhanced-Raman-scattering-inducing nanoprobe for spectrochemical analysis
    David L Stokes
    Advanced Monitoring Development Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Appl Spectrosc 58:292-8. 2004
    ..As a demonstration of the SERS-inducing capability of the probe, Raman spectra were recorded for glass surfaces coated with brilliant cresyl blue and p-aminobenzoic acid before and during contact with the SERS-inducing nanoprobe...
  13. ncbi request reprint Plasmonics-based nanostructures for surface-enhanced Raman scattering bioanalysis
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, TN, USA
    Methods Mol Biol 300:255-83. 2005
    ....
  14. ncbi request reprint Application of a miniature biochip using the molecular beacon probe in breast cancer gene BRCA1 detection
    Mustafa Culha
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Life Science Division, Bethel Valley Road, MS 6101, P O Box 2008, Oak Ridge, TN 37831 6101, USA
    Biosens Bioelectron 19:1007-12. 2004
    ..The detection of BRCA1 gene is successfully demonstrated in solution and the limit of detection (LOD) is estimated as 70 nM...
  15. ncbi request reprint Screening for the breast cancer gene (BRCA1) using a biochip system and molecular beacon probes immobilized on solid surfaces
    Mustafa Culha
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Bethel Valley Road, MS 6101 P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    J Biomed Opt 9:439-43. 2004
    ..The detection of the BRCA1 gene using an MB probe is successfully demonstrated and expands the use of the CMOS biochip for medical applications...
  16. ncbi request reprint Detection of human immunodeficiency virus type 1 DNA sequence using plasmonics nanoprobes
    Musundi B Wabuyele
    Center for Advanced Biomedical Photonics, Oak Ridge National Laboratory, Tennnessee 37831, USA
    Anal Chem 77:7810-5. 2005
    ..The potential for combining the spectral selectivity and high sensitivity of the SERS process with inherent molecular specificity of DNA hairpins to diagnose molecular target sequences in homogeneous solutions is discussed...
  17. ncbi request reprint Near-field scanning optical microscopy for bioanalysis at nanometer resolution
    Musundi B Wabuyele
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Oak Ridge, TN, USA
    Methods Mol Biol 300:437-52. 2005
    ..To illustrate possible applications, imaging of green fluorescent proteins and biomolecules associated with multidrug resistance proteins in tumor cells will be demonstrated using NSOM...
  18. ncbi request reprint Optical nanosensors for detecting proteins and biomarkers in individual living cells
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA
    Methods Mol Biol 300:383-401. 2005
    ..A photometric detection system is used to detect the optical signal (e.g., fluorescence) originating from the analyte molecules or from the analyte-bioreceptor reaction...
  19. ncbi request reprint Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip
    Minoo D F Askari
    Advanced Monitoring Development Group, Life Sciences Division, Graduate School of Biomedical Sciences, Oak Ridge National Laboratory and University of Tennessee Oak Ridge, Oak Ridge, TN 37831 6101, USA
    Cancer Detect Prev 26:331-42. 2002
    ..Linearity of biochip for quantitative measurements was demonstrated. Results demonstrated utility of this multi-functional biochip as a useful detection technology with applications in biological and clinical laboratories...
  20. ncbi request reprint Near-real-time determination of hydrogen peroxide generated from cigarette smoke
    Fei Yan
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, TN 37831 6101, USA
    J Environ Monit 7:681-7. 2005
    ....
  21. ncbi request reprint Hyperspectral imaging system using acousto-optic tunable filter for flow cytometry applications
    Paul M Kasili
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Cytometry A 69:835-41. 2006
    ..HSI is a promising additional feature to flow cytometry since it can provide both spatial (image format) and spectral information in addition to the multiparameter information already available from flow cytometry measurements...
  22. ncbi request reprint Protein nanotechnology: the new frontier in biosciences
    Tuan Vo-Dinh
    Center for Advanced Biomedical Photonics, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA
    Methods Mol Biol 300:1-13. 2005
    ..This chapter provides a brief overview of the field of nanotechnology and its applications to the study, design, and use of protein systems in biology and medicine...
  23. ncbi request reprint A miniature biochip system for detection of aerosolized Bacillus globigii spores
    Dimitra N Stratis-Cullum
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, Bethel Valley Road, MS 6101 P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Anal Chem 75:275-80. 2003
    ..In addition, these studies have included investigations into the tradeoff between assay time and sensitivity...
  24. ncbi request reprint Integrated CMOS microchip system with capillary array electrophoresis
    Myong Song Joon
    Advanced Biomedical Science and Technology Group, Life Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, Tennessee 37831 6101, USA
    Anal Bioanal Chem 373:399-403. 2002
    ..The miniaturized and integrated CMOS microchip system used in this work had great potential for combination with a variety of microfabricated devices for biomedical research...
  25. ncbi request reprint Surface-enhanced Raman scattering for cancer diagnostics: detection of the BCL2 gene
    Mustafa Culha
    Advanced Biomedical Science and Technology Group, Oak Ridge National Laboratory, TN 37831 6101, USA
    Expert Rev Mol Diagn 3:669-75. 2003
    ..The probes do not involve the use of radioactive labels and have great potential to provide both sensitivity and selectivity. The utility of this approach is investigated...
  26. ncbi request reprint Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy
    Minoo D F Askari
    Department of Pathology, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA
    Biopolymers 73:510-23. 2004
    ..It is concluded that Fhit protein expression maintained apoptotic function by altering the Delta Psi(m) and by enhancing cytochrome c efflux from the mitochondria...
  27. pmc Intensified biochip system using chemiluminescence for the detection of Bacillus globigii spores
    Dimitra N Stratis-Cullum
    US Army Research Laboratory, AMSRD ARL SE EO, 2800 Powder Mill Road, Adelphi, MD, 20783, USA
    Anal Bioanal Chem 391:1655-60. 2008
    ..Moreover, the chemiluminescence method, combined with the self-contained biochip design, allows for a simple, compact system that does not require laser excitation and is readily adaptable to field use...
  28. ncbi request reprint Time-resolved optical tomography using short-pulse laser for tumor detection
    Gopalendu Pal
    Mechanical and Aerospace Engineering Department, Florida Institute of Technology, 150 West University Boulevard, Melbourne, 32901 0000, USA
    Appl Opt 45:6270-82. 2006
    ....
  29. ncbi request reprint Laser-induced fluorescence spectroscopy for in vivo diagnosis of non-melanoma skin cancers
    Masoud Panjehpour
    Thompson Cancer Survival Center, Knoxville, Tennessee 37916, USA
    Lasers Surg Med 31:367-73. 2002
    ..The objective of this study was to determine whether in vivo laser-induced fluorescence spectroscopy alone at the visible excitation wavelength of 410 nm could be used to detect non-melanoma skin cancers...
  30. ncbi request reprint Multi-analyte analysis system using an antibody-based biochip
    Maria Cruz Moreno-Bondi
    Department of Analytical Chemistry, Facultad de Quimica, Universidad Complutense, 28040 Madrid, Spain
    Anal Bioanal Chem 375:120-4. 2003
    ..The usefulness of the Ab biochip is illustrated by the measurements of immunoglobulin G (IgG) used as the model analyte system. The detection limit for Cy5-labeled IgG molecules was 13 pg...
  31. ncbi request reprint Experimental and numerical analysis of short-pulse laser interaction with tissue phantoms containing inhomogeneities
    Champak Das
    Department of Mechanical and Aerospace Engineering, Florida Institute of Technology, 150 West University Boulevard, Melbourne, Florida 32901, USA
    Appl Opt 42:5173-80. 2003
    ..The temporal and spatial profiles of the scattered optical signals are compared with the numerical modeling results obtained by solving the transient radiative transport equation by using the discrete ordinates technique...
  32. ncbi request reprint Monitoring intracellular proteins using fluorescence techniques: from protein synthesis and localization to activity
    Pierre M Viallet
    Quantitative Microfluorimetry Group, Laboratory of Physicochemical Biology of Integrated Systems, University of Perpignan, F 66840 Perpignan, France
    Curr Protein Pept Sci 4:375-88. 2003
    ..These specific locations can be obtained from in vitro studies of 3D conformational changes that occur during protein docking...
  33. ncbi request reprint Optoacoustic diffraction tomography: analysis of algorithms
    Stephen J Norton
    Geophex, Ltd, Raleigh, North Carolina 27603, USA
    J Opt Soc Am A Opt Image Sci Vis 20:1859-66. 2003
    ..Analytical inversion formulas are derived in both two and three dimensions. The effects of band-limited data on image quality are also investigated...
  34. ncbi request reprint Photodynamic therapy of Barrett's esophagus: ablation of Barrett's mucosa and reduction in p53 protein expression after treatment
    Masoud Panjehpour
    Laser Center, Thompson Cancer Survival Center, Knoxville, TN 37916, USA
    Anticancer Res 28:485-9. 2008
    ..Following successful PDT, Barrett's mucosa is replaced with neosquamous mucosa. The objective of this study was to compare the expression of p53 protein in neosquamous mucosa as compared to that in HGD samples not treated with PDT...