C M Nutting

Summary

Country: USA

Publications

  1. ncbi Reduction of small and large bowel irradiation using an optimized intensity-modulated pelvic radiotherapy technique in patients with prostate cancer
    C M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, UK
    Int J Radiat Oncol Biol Phys 48:649-56. 2000
  2. ncbi Retinoids in the prevention of bladder cancer
    C M Nutting
    Institute of Cancer Research and Royal Marsden NHS Trust, Fulham Road, London SW3 6JJ, UK
    Expert Rev Anticancer Ther 1:541-5. 2001
  3. ncbi Prostate cancer--the Royal Marsden conformal experience
    Christopher M Nutting
    Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, UK
    Front Radiat Ther Oncol 37:196-9. 2002
  4. ncbi Intensity-modulated radiotherapy reduces lung irradiation in patients with carcinoma of the oesophagus
    Christopher M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, UK
    Front Radiat Ther Oncol 37:128-31. 2002
  5. ncbi Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid gland
    C M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research, Surrey, SM2 5PT, Sutton, UK
    Radiother Oncol 60:173-80. 2001
  6. ncbi A comparison of conformal and intensity-modulated techniques for oesophageal radiotherapy
    C M Nutting
    Academic Department of Radiotherapy, The Institute of Cancer Research and The Royal Marsden NHS Trust, Downs Road, Sutton, SM2 5PT, Surrey, UK
    Radiother Oncol 61:157-63. 2001
  7. ncbi Pre-trial quality assurance processes for an intensity-modulated radiation therapy (IMRT) trial: PARSPORT, a UK multicentre Phase III trial comparing conventional radiotherapy and parotid-sparing IMRT for locally advanced head and neck cancer
    C H Clark
    Department of Physics, Royal Marsden NHS Foundation Trust, London and Sutton, Surrey, UK
    Br J Radiol 82:585-94. 2009
  8. ncbi Potential role of intensity-modulated radiotherapy in the treatment of tumors of the maxillary sinus
    E J Adams
    Joint Department of Physics, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, UK
    Int J Radiat Oncol Biol Phys 51:579-88. 2001
  9. ncbi Optimisation of radiotherapy for carcinoma of the parotid gland: a comparison of conventional, three-dimensional conformal, and intensity-modulated techniques
    C M Nutting
    Department of Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Trust, Downs Road, Surrey, Sutton, UK
    Radiother Oncol 60:163-72. 2001
  10. ncbi Case report. Isolated intrathyroid metastasis from undifferentiated and squamous carcinoma of the head and neck: the case for surgery and re-irradiation
    P Jankowska
    Head and Neck Unit, Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Br J Radiol 81:e154-61. 2008

Collaborators

Detail Information

Publications32

  1. ncbi Reduction of small and large bowel irradiation using an optimized intensity-modulated pelvic radiotherapy technique in patients with prostate cancer
    C M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, UK
    Int J Radiat Oncol Biol Phys 48:649-56. 2000
    ..To investigate the role of intensity-modulated radiation therapy (IMRT) to irradiate the prostate gland and pelvic lymph nodes while sparing critical pelvic organs, and to optimize the number of beams required...
  2. ncbi Retinoids in the prevention of bladder cancer
    C M Nutting
    Institute of Cancer Research and Royal Marsden NHS Trust, Fulham Road, London SW3 6JJ, UK
    Expert Rev Anticancer Ther 1:541-5. 2001
    ..This article reviews the data on this subject and includes in vitro and in vivo preclinical studies as well as the clinical studies performed in the secondary prevention of this disease...
  3. ncbi Prostate cancer--the Royal Marsden conformal experience
    Christopher M Nutting
    Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, UK
    Front Radiat Ther Oncol 37:196-9. 2002
  4. ncbi Intensity-modulated radiotherapy reduces lung irradiation in patients with carcinoma of the oesophagus
    Christopher M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, UK
    Front Radiat Ther Oncol 37:128-31. 2002
  5. ncbi Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid gland
    C M Nutting
    Academic Department of Radiotherapy, Institute of Cancer Research, Surrey, SM2 5PT, Sutton, UK
    Radiother Oncol 60:173-80. 2001
    ..A simultaneous integrated boost technique with five equispaced fields produced the best dose distribution. IMRT should reduce the risk of myelopathy or may allow dose escalation in patients with thyroid cancer...
  6. ncbi A comparison of conformal and intensity-modulated techniques for oesophageal radiotherapy
    C M Nutting
    Academic Department of Radiotherapy, The Institute of Cancer Research and The Royal Marsden NHS Trust, Downs Road, Sutton, SM2 5PT, Surrey, UK
    Radiother Oncol 61:157-63. 2001
    ..Thus, IMRT with a few carefully chosen field directions may lead to a modest reduction in pneumonitis, or allow tumour dose escalation within the currently accepted lung toxicity...
  7. ncbi Pre-trial quality assurance processes for an intensity-modulated radiation therapy (IMRT) trial: PARSPORT, a UK multicentre Phase III trial comparing conventional radiotherapy and parotid-sparing IMRT for locally advanced head and neck cancer
    C H Clark
    Department of Physics, Royal Marsden NHS Foundation Trust, London and Sutton, Surrey, UK
    Br J Radiol 82:585-94. 2009
    ..All 10 participating centres achieved implementation of a comprehensive and robust IMRT programme for treatment of head and neck cancer...
  8. ncbi Potential role of intensity-modulated radiotherapy in the treatment of tumors of the maxillary sinus
    E J Adams
    Joint Department of Physics, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, UK
    Int J Radiat Oncol Biol Phys 51:579-88. 2001
    ....
  9. ncbi Optimisation of radiotherapy for carcinoma of the parotid gland: a comparison of conventional, three-dimensional conformal, and intensity-modulated techniques
    C M Nutting
    Department of Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Trust, Downs Road, Surrey, Sutton, UK
    Radiother Oncol 60:163-72. 2001
    ..Clinical trials are required to confirm the clinical benefits of these improved dose distributions...
  10. ncbi Case report. Isolated intrathyroid metastasis from undifferentiated and squamous carcinoma of the head and neck: the case for surgery and re-irradiation
    P Jankowska
    Head and Neck Unit, Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Br J Radiol 81:e154-61. 2008
    ....
  11. ncbi Clinical evaluation of intensity-modulated radiotherapy for head and neck cancers
    S A Bhide
    Head and Neck Unit, Royal Marsden Hospital, Sutton, Surrey, UK
    Br J Radiol 85:487-94. 2012
    ..In addition, we briefly discuss the role of image guidance in head and neck IMRT, and future directions in this area...
  12. ncbi Potential improvements in the therapeutic ratio of prostate cancer irradiation: dose escalation of pathologically identified tumour nodules using intensity modulated radiotherapy
    C M Nutting
    Department of Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, SM2 5PT, UK
    Br J Radiol 75:151-61. 2002
    ..Improvements in prostate imaging and prostate immobilization are required before clinical implementation would be possible. Clinical trials are required to confirm the clinical benefits of these improved dose distributions...
  13. ncbi Sequential induction chemotherapy followed by radical chemo-radiation in the treatment of locoregionally advanced head-and-neck cancer
    S A Bhide
    Head and Neck Unit, Royal Marsden Hospital, London SW3 6JJ, UK
    Br J Cancer 99:57-62. 2008
    ..Distant recurrence rates are lower with equivalent local control and survival compared to chemo-radiation alone (historical controls)...
  14. ncbi Phase III pilot study of dose escalation using conformal radiotherapy in prostate cancer: PSA control and side effects
    D P Dearnaley
    Academic Department of Radiotherapy and Oncology, Institute of Cancer Research, Sutton, Surrey SM2 5PT, UK
    Br J Cancer 92:488-98. 2005
    ..Data from this randomised pilot study informed the Data Monitoring Committee of the Medical Research Council RT 01 Trial and the two studies will be combined in subsequent meta-analysis...
  15. ncbi Beam-orientation optimization of intensity-modulated radiotherapy: clinical application to parotid gland tumours
    C G Rowbottom
    Joint Department of Physics, Institute of Cancer Research and the Royal Marsden NHS Trust, Downs Road, Sutton, SM2 5PT, Surrey, UK
    Radiother Oncol 59:169-77. 2001
    ..CONCLUSIONS: In conclusion, IMB-orientation optimization for head and neck treatment sites can produce improvements in treatment plans with only a few fields...
  16. ncbi Epirubicin, cisplatin and protracted venous infusion 5-Fluorouracil chemotherapy for advanced salivary adenoid cystic carcinoma
    P J Ross
    The Head and Neck Unit, Royal Marsden NHS Trust, Fulham Road, London SW3 6JJ, UK
    Clin Oncol (R Coll Radiol) 21:311-4. 2009
    ..Chemotherapy is reserved for treatment of symptomatic recurrence. We evaluated the combination of epirubicin, cisplatin and protracted venous infusion 5-fluorouracil (ECF) in the management of ACC...
  17. ncbi Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitisers
    C Powell
    The Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Cancer Treat Rev 36:566-75. 2010
    ..Clinical trials to assess the toxicity and potential benefit of combining radiotherapy with PARP inhibition are now needed...
  18. ncbi Recent advances in radiotherapy
    S A Bhide
    Institute of Cancer Research and Royal Marsden Hospital, Fulham Road, London, UK
    BMC Med 8:25. 2010
    ..Various hardware and software tools are under investigation for optimal IGRT...
  19. ncbi Clinical use of intensity-modulated radiotherapy: part II
    M T Guerrero Urbano
    Radiotherapy Department and Head and Neck Unit, Institute of Cancer Research and Royal Marsden NHS Trust, London and Surrey, UK
    Br J Radiol 77:177-82. 2004
    ..Indications for breast IMRT data are reviewed, and current data presented. Further data from randomized trials are required to confirm the anticipated benefits of IMRT in patients...
  20. ncbi Otological toxicity after postoperative radiotherapy for parotid tumours
    S A Bhide
    Head and Neck Unit, Institute of Cancer Research and Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    Clin Oncol (R Coll Radiol) 19:77-82. 2007
    ..In particular, the close proximity of the auditory apparatus, which receives a significant radiation dose, results in significant toxicity in a proportion of patients. Here we review auditory toxicity after radiation to the parotid bed...
  21. ncbi Future perspectives for health related quality of life (HRQOL) studies in head and neck cancer
    R C Dwivedi
    Head and Neck Unit, Royal Marsden NHS, Fulham Road, London SW3 6JJ, UK
    G Ital Med Lav Ergon 31:B17-20. 2009
    ..Most importantly, in order to link research to clinical practice, health related QOL (HRQOL) studies should be devised and utilised in a way as to provide clinically meaningful data to the treating physician useful for patient' care...
  22. ncbi Implementation of IMRT in the radiotherapy department
    H A McNair
    Department of Radiotherapy, Royal Marsden NHS Trust and Institute of Cancer Research, Downs Road, Sutton, Surrey, UK
    Br J Radiol 76:850-6. 2003
    ..Training of radiographers, clinicians and physicists is critical, and both team-work and communication are vital to ensure a smooth transition from 3DCRT to IMRT delivery in the clinic...
  23. ncbi Residual or recurrent head and neck cancer presenting with nerve root compression affecting the upper limbs
    R L Mendes
    Head and Neck Unit, Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Br J Radiol 77:688-90. 2004
    ..In this paper, we report three patients with residual or relapsed SCCHN who presented with symptoms and signs of nerve root compression affecting the upper limbs caused by locoregional lymphatic spread of disease...
  24. ncbi Clinical use of intensity-modulated radiotherapy: part I
    M T Guerrero Urbano
    Radiotherapy Department and Head and Neck Unit, Institute of Cancer Research and Royal Marsden NHS Trust, Fulham Road, London SW3 6JJ, UK
    Br J Radiol 77:88-96. 2004
    ..To date, the majority of reports concern patients treated in the context of clinical trials, and for most tumour types longer term follow up of treated patients will be required to confirm the clinical benefits of IMRT...
  25. ncbi Intensity-modulated radiotherapy improves target coverage, spinal cord sparing and allows dose escalation in patients with locally advanced cancer of the larynx
    Catharine H Clark
    Joint Department of Physics, The Royal Marsden NHS Trust, Fulham Road, London SW3 6JJ, UK
    Radiother Oncol 70:189-98. 2004
    ..6)Gy. CONCLUSIONS: IMRT offers improved target homogeneity and reduces irradiation of the SC. This sparing of normal tissue structures is sufficient that significant dose escalation of both the larynx and lymph nodes may be possible...
  26. ncbi In regard to Lee et al., IJROBP 2002;53:630-637
    Catharine H Clark
    Int J Radiat Oncol Biol Phys 55:1150; author reply 1150-1. 2003
  27. ncbi Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging
    Mandy Humphreys
    Radiotherapy Department, Royal Marsden NHS Trust, London, UK
    Radiother Oncol 77:39-44. 2005
    ..9, 2.6 and 3.3 mm, respectively. CONCLUSIONS: This head and neck immobilisation system is of sufficient accuracy for its use with IMRT treatments and a 3 mm CTV-PTV margin has been adopted...
  28. ncbi The impact of introducing intensity modulated radiotherapy into routine clinical practice
    Elizabeth A Miles
    Radiotherapy Department, Royal Marsden NHS Foundation Trust, London and Sutton, UK
    Radiother Oncol 77:241-6. 2005
    ..IMRT has been integrated smoothly and efficiently into the existing treatment working day. This preliminary study suggests that IMRT could be a routine treatment with efficient use of current radiotherapy resources...
  29. ncbi Clinical implementation of dynamic and step-and-shoot IMRT to treat prostate cancer with high risk of pelvic lymph node involvement
    Elizabeth J Adams
    Joint Department of Physics, The Royal Marsden NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
    Radiother Oncol 70:1-10. 2004
    ..QA results have shown accurate and reproducible delivery for both techniques, giving increased confidence in the techniques and allowing a reduction in the QA program...
  30. ncbi Intensity-modulated radiotherapy in patients with locally advanced rectal cancer reduces volume of bowel treated to high dose levels
    M Teresa Guerrero Urbano
    Department of Clinical Oncology, Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    Int J Radiat Oncol Biol Phys 65:907-16. 2006
    ..Reducing the number of beams did not reduce bowel sparing and the five-field customized segmented IMRT plan is a reasonable technique to be tested in clinical trials...
  31. ncbi Intensity Modulated Radiotherapy (IMRT) in locally advanced thyroid cancer: acute toxicity results of a phase I study
    Teresa Guerrero Urbano
    Head and Neck Unit, Royal Marsden Hospital, London, UK
    Radiother Oncol 85:58-63. 2007
    ..This phase 1 study was designed to determine the toxicity of accelerated fractionation IMRT in locally advanced thyroid cancer...
  32. ncbi A phase I study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer
    Teresa Guerrero Urbano
    Head and Neck Unit, Royal Marsden Hospital, Surrey, UK
    Radiother Oncol 85:36-41. 2007
    ..This study aims to determine the safety of dose-escalated chemo-IMRT for larynx preservation in locally advanced head and neck cancer...