Richard G Wunderink

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin
    Marin H Kollef
    Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Intensive Care Med 30:388-94. 2004
  2. ncbi request reprint Methicillin-Resistant S. aureus Ventilator-Associated Pneumonia: Strategies to Prevent and Treat
    Anna P Lam
    Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Semin Respir Crit Care Med 27:92-103. 2006
  3. doi request reprint How important is methicillin-resistant Staphylococcus aureus as a cause of community-acquired pneumonia and what is best antimicrobial therapy?
    Richard G Wunderink
    Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Infect Dis Clin North Am 27:177-88. 2013
  4. doi request reprint Adjunctive therapy in community-acquired pneumonia
    Richard G Wunderink
    Department of Medicine, Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair, Chicago, IL 60611, USA
    Semin Respir Crit Care Med 33:311-8. 2012
  5. doi request reprint Rapid response team-triggered procalcitonin measurement predicts infectious intensive care unit transfers*
    Richard G Wunderink
    Department of Medicine, Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Crit Care Med 40:2090-5. 2012
  6. doi request reprint Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study
    Richard G Wunderink
    Department of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Clin Infect Dis 54:621-9. 2012
  7. pmc A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia
    Pierre Francois Laterre
    St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 13:R36. 2009
  8. ncbi request reprint Nosocomial pneumonia, including ventilator-associated pneumonia
    Richard G Wunderink
    Pulmonary and Critical Care Division, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 14 044, Chicago, IL 60611, USA
    Proc Am Thorac Soc 2:440-4. 2005
  9. ncbi request reprint Community-acquired pneumonia: pathophysiology and host factors with focus on possible new approaches to management of lower respiratory tract infections
    Richard G Wunderink
    Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 14 044, Chicago, IL 60611, USA
    Infect Dis Clin North Am 18:743-59, vii. 2004
  10. doi request reprint Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: a randomized trial
    Richard G Wunderink
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Respir Crit Care Med 183:1561-8. 2011

Detail Information

Publications62

  1. ncbi request reprint Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin
    Marin H Kollef
    Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Intensive Care Med 30:388-94. 2004
    ..To assess the effect of baseline variables, including treatment, on clinical cure and survival rates in patients with Gram-positive, ventilator-associated pneumonia (VAP)...
  2. ncbi request reprint Methicillin-Resistant S. aureus Ventilator-Associated Pneumonia: Strategies to Prevent and Treat
    Anna P Lam
    Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Semin Respir Crit Care Med 27:92-103. 2006
    ..Treatment with linezolid, which penetrates well into the lung, is associated with higher cure and survival rates. Further data are needed to evaluate the efficacy of new antibiotics in MRSA VAP...
  3. doi request reprint How important is methicillin-resistant Staphylococcus aureus as a cause of community-acquired pneumonia and what is best antimicrobial therapy?
    Richard G Wunderink
    Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Infect Dis Clin North Am 27:177-88. 2013
    ..The consistent trend toward better outcomes for documented MRSA pneumonia suggests that linezolid be considered the drug of choice for documented MRSA CAP, especially for CA-MRSA...
  4. doi request reprint Adjunctive therapy in community-acquired pneumonia
    Richard G Wunderink
    Department of Medicine, Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair, Chicago, IL 60611, USA
    Semin Respir Crit Care Med 33:311-8. 2012
    ..Other therapies have theoretical benefit but are not yet in the stage of clinical trials...
  5. doi request reprint Rapid response team-triggered procalcitonin measurement predicts infectious intensive care unit transfers*
    Richard G Wunderink
    Department of Medicine, Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Crit Care Med 40:2090-5. 2012
    ..Determine if procalcitonin at the time of initial rapid response team activation identifies patients who are likely to need subsequent intensive care unit transfer...
  6. doi request reprint Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study
    Richard G Wunderink
    Department of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Clin Infect Dis 54:621-9. 2012
    ..This study prospectively assessed efficacy and safety of linezolid, compared with a dose-optimized vancomycin regimen, for treatment of MRSA nosocomial pneumonia...
  7. pmc A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia
    Pierre Francois Laterre
    St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 13:R36. 2009
    ....
  8. ncbi request reprint Nosocomial pneumonia, including ventilator-associated pneumonia
    Richard G Wunderink
    Pulmonary and Critical Care Division, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 14 044, Chicago, IL 60611, USA
    Proc Am Thorac Soc 2:440-4. 2005
    ..Adequate treatment of an initial infection is required for reversal of the temporary immunoparalysis, whereas specific immunomodulatory therapies can reverse the markers of immunoparalysis and may decrease the risk of infection...
  9. ncbi request reprint Community-acquired pneumonia: pathophysiology and host factors with focus on possible new approaches to management of lower respiratory tract infections
    Richard G Wunderink
    Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 14 044, Chicago, IL 60611, USA
    Infect Dis Clin North Am 18:743-59, vii. 2004
    ..This article reviews genetic variation in the molecules involved in the known patho-genic mechanisms of CAP, including cough, bacterial recognition, inflammation and the compensatory anti-inflammatory response,and organ dysfunction...
  10. doi request reprint Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: a randomized trial
    Richard G Wunderink
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Respir Crit Care Med 183:1561-8. 2011
    ..A systemic inhibitor of coagulation, tifacogin (recombinant human tissue factor pathway inhibitor) seemed to provide mortality benefit in the sCAP subgroup of a previous sepsis trial...
  11. ncbi request reprint Genetics of community-acquired pneumonia
    Richard G Wunderink
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Semin Respir Crit Care Med 26:553-62. 2005
    ..The real value of these genetic studies in CAP and other severe infections will be when the management of an individual patient can be optimized by therapy based on the individual's genotype for molecules important in outcome...
  12. pmc Influenza and bacterial pneumonia--constant companions
    Richard G Wunderink
    Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, 676 North St, Clair Street, Suite 14 044, Chicago, IL 60611, USA
    Crit Care 14:150. 2010
    ..Given the frequency of viral pneumonia and diagnostic limitations, empirical antivirals may be underutilized in community-acquired pneumonia. Thankfully, increasingly effective vaccines appear to disrupt this synergistic relationship...
  13. ncbi request reprint [Assessment of patients with poor resolution of HAP]
    Richard G Wunderink
    Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine Chicago, Illinois, USA
    Enferm Infecc Microbiol Clin 23:52-7. 2005
    ..Biochemical markers may be more accurate than clinical but still don't discriminate between causes. The appropriate diagnostic strategy and treatment algorithms have not been fully addressed and more research is clearly needed...
  14. ncbi request reprint Early microbiological response to linezolid vs vancomycin in ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus
    Richard G Wunderink
    Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Chest 134:1200-7. 2008
    ..This prospective, open-label, multicenter clinical trial compared the early microbiological efficacy of linezolid (LZD) therapy with that of vancomycin (VAN) therapy in patients with MRSA VAP...
  15. doi request reprint Scenario 2: community-acquired pneumonia requiring hospitalization but not requiring admission to an intensive care unit
    Richard G Wunderink
    Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Clin Infect Dis 47:S186-8. 2008
    ..The patient is a 65-year-old woman with community-acquired pneumonia of sufficient severity to require hospitalization. Factors important for consideration in clinical trials are illustrated...
  16. doi request reprint Adjunctive therapy in community-acquired pneumonia
    Richard G Wunderink
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Semin Respir Crit Care Med 30:146-53. 2009
    ..Other therapies have theoretical benefit but are not yet in the stage of clinical trials...
  17. doi request reprint Expanded clinical presentation of community-acquired methicillin-resistant Staphylococcus aureus pneumonia
    L Jason Lobo
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Chest 138:130-6. 2010
    ..The frequency of occurrence, risk factors, and optimal treatment of CA-MRSA CAP are unclear...
  18. pmc Empiric antibiotic, mechanical ventilation, and central venous catheter duration as potential factors mediating the effect of a checklist prompting intervention on mortality: an exploratory analysis
    Curtis H Weiss
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Suite 1400 676 N, St, Clair, Chicago, IL 60611, USA
    BMC Health Serv Res 12:198. 2012
    ..We sought to examine the degree to which these process of care improvements explained the observed difference in hospital mortality between the group that received prompting and an unprompted control group...
  19. doi request reprint The role of MRSA in healthcare-associated pneumonia
    Anna P Lam
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Semin Respir Crit Care Med 30:52-60. 2009
    ..The limitations of vancomycin and evidence for superior outcomes with linezolid are reviewed. Alternatives for community-acquired strains and future options are mentioned...
  20. doi request reprint Reliability of the validated clinical diagnosis of pneumonia on validated outcomes after intracranial hemorrhage
    Andrew M Naidech
    Northwestern University s Feinberg School of Medicine, Chicago, IL 60611, USA
    J Crit Care 27:527.e7-11. 2012
    ..We sought to determine the interrater reliability of diagnosis of PNU and its impact on resource utilization and functional outcomes in a high-risk population...
  21. pmc The effect of rosuvastatin in a murine model of influenza A infection
    Kathryn A Radigan
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
    PLoS ONE 7:e35788. 2012
    ..We hypothesized that rosuvastatin would decrease viral replication, attenuate lung injury, and improve mortality following influenza A infection in mice...
  22. doi request reprint Surrogate markers and microbiologic end points
    Richard G Wunderink
    Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Clin Infect Dis 51:S126-30. 2010
    ..A decreasing or low procalcitonin level after initiation of antibiotic treatment correlates well with bacterial eradication...
  23. doi request reprint Management of community-acquired pneumonia in adults
    Grant W Waterer
    University of Western Australia, Perth, Australia
    Am J Respir Crit Care Med 183:157-64. 2011
    ....
  24. pmc A clinical trial comparing physician prompting with an unprompted automated electronic checklist to reduce empirical antibiotic utilization
    Curtis H Weiss
    1Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 2Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
    Crit Care Med 41:2563-9. 2013
    ..To determine whether face-to-face prompting of critical care physicians reduces empirical antibiotic utilization compared to an unprompted electronic checklist embedded within the electronic health record...
  25. ncbi request reprint Prompting physicians to address a daily checklist for antibiotics: do we need a co-pilot in the ICU?
    Curtis H Weiss
    Pulmonary and Critical Care Division, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Curr Opin Crit Care 19:448-52. 2013
    ..We reviewed the recent literature on implementation strategies in the intensive care unit, with particular attention to antibiotic therapy...
  26. doi request reprint Bronchoalveolar lavage amylase is associated with risk factors for aspiration and predicts bacterial pneumonia
    Curtis H Weiss
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Crit Care Med 41:765-73. 2013
    ....
  27. ncbi request reprint Potential impact of vancomycin pulmonary distribution on treatment outcomes in patients with methicillin-resistant Staphylococcus aureus pneumonia
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Pharmacotherapy 26:539-50. 2006
    ..The possibility of increased serum vancomycin concentrations as a method to optimize current treatment outcomes is also explored...
  28. pmc Transcriptional events during the recovery from MRSA lung infection: a mouse pneumonia model
    Jiwang Chen
    Department of Medicine, Northwestern University, Chicago, Illinois, USA
    PLoS ONE 8:e70176. 2013
    ..Furthermore, at day 3 lungs displayed significantly lower levels of vascular permeability to albumin, compared to day 1. Collectively, this data helps us elucidate the molecular mechanisms of the recovery after MRSA lung infection. ..
  29. ncbi request reprint Lack of association of the caspase-12 long allele with community-acquired pneumonia in people of African descent
    Jiwang Chen
    Department of Medicine, Northwestern University, Chicago, Illinois, United States of America Section of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 9:e89194. 2014
    ..No statistically significant association between genotype and any measures of CAP severity was found in any cohort. We conclude that the functional CASP12L allele is not a marker for susceptibility and/or severity of CAP. ..
  30. doi request reprint Comparative in vitro stimulation with lipopolysaccharide to study TNFalpha gene expression in fresh whole blood, fresh and frozen peripheral blood mononuclear cells
    Jiwang Chen
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Immunol Methods 357:33-7. 2010
    ..Our results strongly suggest that fresh whole blood is the best choice for in vitro stimulation studies...
  31. ncbi request reprint Severe pseudomonal infections
    Gokhan M Mutlu
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Curr Opin Crit Care 12:458-63. 2006
    ..To review the most recent data on severe Pseudomonas aeruginosa infections. The focus will be on clinical studies with an emphasis on the critically ill...
  32. doi request reprint Derivation of a triage algorithm for chest radiography of community-acquired pneumonia patients in the emergency department
    Demetrios N Kyriacou
    Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Acad Emerg Med 15:40-4. 2008
    ..Community-acquired pneumonia (CAP) accounts for 1.5 million emergency department (ED) patient visits in the United States each year...
  33. pmc Prompting physicians to address a daily checklist and process of care and clinical outcomes: a single-site study
    Curtis H Weiss
    Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Respir Crit Care Med 184:680-6. 2011
    ..Checklists may reduce errors of omission for critically ill patients...
  34. ncbi request reprint Use and limitations of clinical and radiologic diagnosis of pneumonia
    Matthew Mabie
    Research Department, Methodist University Hospital, Memphis, TN, USA
    Semin Respir Infect 18:72-9. 2003
    ..An accurate assessment of the normal, expected response of pneumonia to antibiotic therapy is therefore crucial. A discussion of the clinical response to treatment concludes the article...
  35. pmc Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis
    Sachin Yende
    The Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, Department of Critical Care Medicine, Graduate School of Pubic Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Respir Crit Care Med 177:1242-7. 2008
    ..Survivors of hospitalization for community-acquired pneumonia (CAP) are at increased risk of cardiovascular events, repeat infections, and death in the following months but the cause is unknown...
  36. doi request reprint Evaluation of ICU admission criteria and diagnostic methods for patients with severe community-acquired pneumonia: current practice survey
    Marcos I Restrepo
    Chest 133:828-9. 2008
  37. doi request reprint There is no "cap" on the importance of community-acquired pneumonia in the ICU
    Andrew F Shorr
    Chest 133:590-2. 2008
  38. ncbi request reprint A long and winding road
    Richard G Wunderink
    Crit Care Med 32:1077-9. 2004
  39. ncbi request reprint Clinical relevance of angiotensin-converting enzyme gene polymorphisms to predict risk of mechanical ventilation after coronary artery bypass graft surgery
    Sachin Yende
    Physician Research Network SY, Methodist Healthcare Memphis, Memphis, TN, USA
    Crit Care Med 32:922-7. 2004
    ..Therefore, we examined interactions between these polymorphisms...
  40. ncbi request reprint Intracellular adhesion molecule Gly241Arg polymorphism has no impact on ARDS or septic shock in community-acquired pneumonia
    Michael W Quasney
    Department of Pediatrics, Crippled Children s Foundation Research Center, University of Tennessee, Memphis, 38103, USA
    Chest 121:85S-86S. 2002
  41. ncbi request reprint Genetics of sepsis and pneumonia
    Richard G Wunderink
    Research Department, Methodist LeBonheur Healthcare, Memphis, Tennessee, USA
    Curr Opin Crit Care 9:384-9. 2003
    ..Recent association studies in pneumonia and sepsis will be reviewed...
  42. ncbi request reprint Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia
    Richard G Wunderink
    Methodist Healthcare Memphis and the University of Tennessee, Memphis, Tennessee 38104 3499, USA
    Clin Ther 25:980-92. 2003
    ....
  43. ncbi request reprint Heat shock protein 70-2+1267 AA homozygotes have an increased risk of septic shock in adults with community-acquired pneumonia
    Grant W Waterer
    Department of Medicine, University of Western Australia
    Crit Care Med 31:1367-72. 2003
    ....
  44. ncbi request reprint Association of tumor necrosis factor gene polymorphisms and prolonged mechanical ventilation after coronary artery bypass surgery
    Sachin Yende
    Methodist Healthcare University Hospital, Memphis, TN, USA
    Crit Care Med 31:133-40. 2003
    ....
  45. ncbi request reprint Tumor necrosis factor gene polymorphisms and the variable presentation and outcome of community-acquired pneumonia
    Richard G Wunderink
    Methodist Le Bonheur Healthcare Foundation, University of Tennessee, Memphis, TN, USA
    Chest 121:87S. 2002
  46. ncbi request reprint Association between surfactant protein B + 1580 polymorphism and the risk of respiratory failure in adults with community-acquired pneumonia
    Michael W Quasney
    Division of Critical Care, Department of Pediatrics, University of Tennessee, Memphis, Children s Foundation Research Center of Memphis, Le Bonheur Children s Medical Center, 50 N Dunlap, Memphis, TN 38103, USA
    Crit Care Med 32:1115-9. 2004
    ..The objective was to determine whether the SP-B + 1580 CC genotype is associated with an increased risk of respiratory failure and ARDS in adults with community-acquired pneumonia...
  47. ncbi request reprint Impact of cytokine gene polymorphisms on outcomes of coronary artery bypass graft surgery
    Sachin Yende
    Methodist Healthcare and University of Tennessee, Memphis, TN 38104, USA
    Chest 121:86S. 2002
  48. ncbi request reprint Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
    Lionel A Mandell
    McMaster University Medical School, Hamilton, Ontario, Canada
    Clin Infect Dis 44:S27-72. 2007
  49. ncbi request reprint Genetic polymorphisms that predict outcome and need for treatment in cardiovascular disease
    Sachin Yende
    Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Curr Opin Crit Care 12:420-5. 2006
    ..The focus is on risk of complications or differences in management, rather than only susceptibility to cardiovascular disease itself...
  50. ncbi request reprint Healthcare-associated bacteremia: Stirring the mud
    Richard G Wunderink
    Crit Care Med 34:2685-6. 2006
  51. ncbi request reprint Delayed administration of antibiotics and atypical presentation in community-acquired pneumonia
    Grant W Waterer
    University of Western Australia, School of Medicine and Pharmacology, 4th Floor MRF Building, Royal Perth Hospital, GPO Box X2213, Perth, WA, Australia 6847
    Chest 130:11-5. 2006
    ..We investigated the factors that predict a prolonged TFAD and their association with mortality...
  52. pmc 4G/5G plasminogen activator inhibitor-1 polymorphisms and haplotypes are associated with pneumonia
    Sachin Yende
    CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Respir Crit Care Med 176:1129-37. 2007
    ..Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown...
  53. ncbi request reprint Slow response times: is it the pneumonia or the physician?
    Richard G Wunderink
    Crit Care Med 33:1429-30. 2005
  54. ncbi request reprint Pharmaceutical industry research and cost savings in community-acquired pneumonia
    Lori A Kessler
    Physicians Research Network, Methodist Le Bonheur Healthcare Foundation, Memphis, Tenn 38104, USA
    Am J Manag Care 8:798-800. 2002
    ..To provide financial justification for continuing pharmaceutical research in an environment that has met with increasing resistance from insurance carriers to paying for the care of patients enrolled in research studies...
  55. ncbi request reprint Dollars and sense in the intensive care unit: the costs of ventilator-associated pneumonia
    Andrew F Shorr
    Crit Care Med 31:1582-3. 2003
  56. doi request reprint Health care-associated infection (HAI): a critical appraisal of the emerging threat-proceedings of the HAI Summit
    Marin H Kollef
    Washington University School of Medicine, St Louis, Missouri 63110, USA
    Clin Infect Dis 47:S55-99; quiz S100-1. 2008
    ....
  57. ncbi request reprint High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm
    Lala M Dunbar
    Louisiana State University Medical Center, New Orleans, Louisiana, USA
    Clin Infect Dis 37:752-60. 2003
    ..2% and 92.4% in the 750-mg and 500-mg groups, respectively. These data demonstrate that 750 mg of levofloxacin per day for 5 days is at least as effective as 500 mg per day for 10 days for treatment of mild-to-severe CAP...
  58. ncbi request reprint " 'Tis a gift to be simple..."
    Richard G Wunderink
    Chest 124:777-8. 2003
  59. ncbi request reprint Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia
    Richard G Wunderink
    Methodist Healthcare Memphis and the University of Tennessee, Memphis, TN 38104 3499, USA
    Chest 124:1789-97. 2003
    ..To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA)...
  60. ncbi request reprint Medium-term survival after hospitalization with community-acquired pneumonia
    Grant W Waterer
    Department of Medicine, University of Western Australia, Royal Perth Hospital, Perth, Western Australia, Australia
    Am J Respir Crit Care Med 169:910-4. 2004
    ....
  61. ncbi request reprint A CAP on antibiotic duration
    Richard G Wunderink
    Am J Respir Crit Care Med 174:3-5. 2006
  62. ncbi request reprint Genetic susceptibility to pneumonia
    Grant W Waterer
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, GP0 Box X2213, Perth, Western Australia
    Clin Chest Med 26:29-38. 2005
    ..IL-10 and IL-1 receptor antagonist polymorphisms have an important role in the anti-inflammatory response. Specific organ dysfunction, such as ARDS or DIC, may be related to polymorphisms in specific effector genes...