Peter F Whitington

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Gestational alloimmune liver disease and neonatal hemochromatosis
    Peter F Whitington
    Department of Pediatrics, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    Semin Liver Dis 32:325-32. 2012
  2. ncbi request reprint Neonatal hemochromatosis: fetal liver disease leading to liver failure in the fetus and newborn
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, The Siragusa Transplantation Center, Chicago, IL 60614, USA
    Pediatr Transplant 9:640-5. 2005
  3. ncbi request reprint Neonatal hemochromatosis: is it an alloimmune disease?
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Pediatr Gastroenterol Nutr 40:544-9. 2005
  4. ncbi request reprint Expression of osteopontin correlates with portal biliary proliferation and fibrosis in biliary atresia
    Peter F Whitington
    Department of Pediatrics, Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60614, USA
    Pediatr Res 57:837-44. 2005
  5. ncbi request reprint High-dose immunoglobulin during pregnancy for recurrent neonatal haemochromatosis
    Peter F Whitington
    Department of Pediatrics, Feinberg School of Medicine of Northwestern University, 2300 Children s Plaza Box 57, Children s Memorial Hospital, Chicago, IL 60614, USA
    Lancet 364:1690-8. 2004
  6. doi request reprint Gestational alloimmune liver disease in cases of fetal death
    Peter F Whitington
    Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Pediatr 159:612-6. 2011
  7. ncbi request reprint Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet
    Sean W P Koppe
    Department of Medicine, Division of Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Hepatol 41:592-8. 2004
  8. ncbi request reprint Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin
    Atul Sahai
    Department of Pediatrics, The Feinberg School of Medicine, Northwestern University, Children s Memorial Institute for Education and Research, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 287:G1035-43. 2004
  9. pmc Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion
    Karan M Emerick
    Children s Memorial Hospital, Chicago, IL, USA
    BMC Gastroenterol 8:47. 2008
  10. doi request reprint Growth impairment in children with extrahepatic portal vein obstruction is improved by mesenterico-left portal vein bypass
    Timothy B Lautz
    Department of Surgery, Children s Memorial Hospital, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    J Pediatr Surg 44:2067-70. 2009

Research Grants

Detail Information

Publications55

  1. doi request reprint Gestational alloimmune liver disease and neonatal hemochromatosis
    Peter F Whitington
    Department of Pediatrics, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    Semin Liver Dis 32:325-32. 2012
    ..GALD may produce subacute and chronic fetal liver injury (congenital cirrhosis) typical of NH. It may also produce acute injury and acute liver failure of the fetus and newborn, often with no iron overload or siderosis...
  2. ncbi request reprint Neonatal hemochromatosis: fetal liver disease leading to liver failure in the fetus and newborn
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, The Siragusa Transplantation Center, Chicago, IL 60614, USA
    Pediatr Transplant 9:640-5. 2005
    ..Almost nothing is known about fetal onset liver failure, and there is no literature addressing the subject. This review will address fetal liver disease that leads to liver failure in the fetus or newborn...
  3. ncbi request reprint Neonatal hemochromatosis: is it an alloimmune disease?
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Pediatr Gastroenterol Nutr 40:544-9. 2005
  4. ncbi request reprint Expression of osteopontin correlates with portal biliary proliferation and fibrosis in biliary atresia
    Peter F Whitington
    Department of Pediatrics, Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60614, USA
    Pediatr Res 57:837-44. 2005
    ..These findings suggest a role for OPN in the pathogenesis of biliary atresia...
  5. ncbi request reprint High-dose immunoglobulin during pregnancy for recurrent neonatal haemochromatosis
    Peter F Whitington
    Department of Pediatrics, Feinberg School of Medicine of Northwestern University, 2300 Children s Plaza Box 57, Children s Memorial Hospital, Chicago, IL 60614, USA
    Lancet 364:1690-8. 2004
    ....
  6. doi request reprint Gestational alloimmune liver disease in cases of fetal death
    Peter F Whitington
    Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Pediatr 159:612-6. 2011
    ..To determine whether alloimmune liver disease can be identified as a cause of fetal death...
  7. ncbi request reprint Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet
    Sean W P Koppe
    Department of Medicine, Division of Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Hepatol 41:592-8. 2004
    ..The aim of our study is to determine if PTX attenuates MCD diet induced steatohepatitis and determine the mechanism of this effect...
  8. ncbi request reprint Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin
    Atul Sahai
    Department of Pediatrics, The Feinberg School of Medicine, Northwestern University, Children s Memorial Institute for Education and Research, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 287:G1035-43. 2004
    ..In conclusion, our results demonstrate the development of an obese/diabetic experimental model for NASH in db/db mice and suggest an important role for Ob-Ra and OPN in the pathogenesis of NASH...
  9. pmc Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion
    Karan M Emerick
    Children s Memorial Hospital, Chicago, IL, USA
    BMC Gastroenterol 8:47. 2008
    ..PEBD can reduce disease progression, and examining the alterations in biliary lipid composition may be a prognostic factor for outcome...
  10. doi request reprint Growth impairment in children with extrahepatic portal vein obstruction is improved by mesenterico-left portal vein bypass
    Timothy B Lautz
    Department of Surgery, Children s Memorial Hospital, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    J Pediatr Surg 44:2067-70. 2009
    ..We hypothesized that growth parameters improve after reversal of portal hypertension and restoration of mesenteric venous blood flow to the liver by the mesenterico-left portal vein bypass (MLPVB)...
  11. ncbi request reprint Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium
    Atul Sahai
    Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children s Memorial Research Center, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 291:G55-62. 2006
    ..PI3-kinase plays a central role in signaling the MCD medium-induced steatosis and increased OPN expression, whereas OPN appears to play a role in signaling hepatocyte ALT release but not steatosis...
  12. doi request reprint Novel mechanism of fetal hepatocyte injury in congenital alloimmune hepatitis involves the terminal complement cascade
    Xiaomin Pan
    Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Hepatology 51:2061-8. 2010
    ..Findings in both groups suggest that hepatocytes have mechanisms to protect against MAC, including a biliary pathway for its excretion...
  13. doi request reprint Graft histology characteristics in long-term survivors of pediatric liver transplantation
    Udeme D Ekong
    Department of Pediatrics, Children s Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL 60614, USA
    Liver Transpl 14:1582-7. 2008
    ..The cause of this fibrosis is uncertain, and normal alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase levels do not exclude the presence of significant fibrosis...
  14. ncbi request reprint Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway
    Rohit Kohli
    Department of Pediatrics, Children s Memorial Hospital, Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614, USA
    J Biol Chem 282:21327-36. 2007
    ..Our findings suggest a common path for response to altered nutrition involving mitochondrial ROS-dependent PI 3-kinase pathway regulation, leading to steatosis...
  15. doi request reprint Neonatal iron overload and tissue siderosis due to gestational alloimmune liver disease
    Silvana Bonilla
    Children s Memorial Research Center, The Feinberg School of Medicine of Northwestern University, Chicago, IL 60614, USA
    J Hepatol 56:1351-5. 2012
    ..Under the resulting conditions of iron overload, the tissue pattern of extrahepatic siderosis is determined by the normal expression of proteins involved in the import of non-transferrin-bound iron and the export of cellular iron...
  16. ncbi request reprint Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model
    Atul Sahai
    Department of Pediatrics, Children s Memorial Institute for Education and Research, Northwestern University, 2300 Children s Plaza, Box 212, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 287:G264-73. 2004
    ..In conclusion, our results demonstrate an upregulation of OPN expression early in the development of steatohepatitis and suggest an important role for OPN in signaling the onset of liver injury and fibrosis in experimental NASH...
  17. ncbi request reprint Regional variation and use of exception letters for cadaveric liver allocation in children with chronic liver disease
    Paolo R Salvalaggio
    Department of Surgery, The Siragusa Transplantation Center, Children s Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago 60614, IL, USA
    Am J Transplant 5:1868-74. 2005
    ..Regional variation suggests that PELD has not resulted in standardization of listing practices in pediatric liver transplantation...
  18. pmc Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia
    Benjamin L Shneider
    Department of Pediatrics, Children s Hospital Pittsburgh of UPMC, Pittsburgh, PA 15224, USA
    Pediatrics 130:e607-14. 2012
    ..In this prospective multicenter study, we assessed the prevalence of FSV deficiency in infants with BA who received this FSV/TPGS preparation...
  19. pmc Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease
    Miriam B Vos
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Pediatr Gastroenterol Nutr 47:481-5. 2008
    ..Cytokeratin 18 (CK18) is an intracellular protein released into the blood by both necrosis and apoptosis of hepatocytes. Levels of CK18 have not been reported previously in children with NAFLD...
  20. ncbi request reprint Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methionine-choline-deficient diet
    Shikha S Sundaram
    Division of Gastroenterology and Hepatology and Nutrition, Departments of Pediatrics, Department of Internal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Physiol Gastrointest Liver Physiol 288:G1321-7. 2005
    ..They also have enhanced TNF-alpha, IL-6, and cytochrome P-450 2E1 expression. We conclude that TTR-Abcb11 mice develop a more rapid hepatitis with less steatosis...
  21. doi request reprint Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin
    Elizabeth B Rand
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr 155:566-71. 2009
    ....
  22. ncbi request reprint Surgically restoring portal blood flow to the liver in children with primary extrahepatic portal vein thrombosis improves fluid neurocognitive ability
    Cara L Mack
    Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, Illinois, USA
    Pediatrics 117:e405-12. 2006
    ..We determined the fluid cognitive ability of children with EHPVT and whether surgically restoring portal blood flow by mesenteric left portal vein bypass (MLPVB) improved it...
  23. pmc Correction of extrahepatic portal vein thrombosis by the mesenteric to left portal vein bypass
    Riccardo Superina
    Department of Surgery, Children s Memorial Hospital, Feinberg School of Medicine of North Western University, Chicago, IL 60614, USA
    Ann Surg 243:515-21. 2006
    ..The treatment of idiopathic EHPVT has been primarily palliative, whereas MLPVB restores hepatic portal flow in patients with EHPVT...
  24. doi request reprint Increased hepatic expression is a major determinant of serum alanine aminotransferase elevation in mice with nonalcoholic steatohepatitis
    Rui Liu
    Department of Pediatrics, Children s Memorial Research Center, Northwestern University, Feinberg School of Medicine, Chicago, IL 60614, USA
    Liver Int 29:337-43. 2009
    ..Aim: We sought to understand the mechanisms by which serum ALT is elevated in a mouse model of experimental fatty liver disease where hepatocyte death is minimal...
  25. doi request reprint Survival after liver transplantation for hepatoblastoma: a 2-center experience
    Marybeth Browne
    Department of Surgery, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL 60614, USA
    J Pediatr Surg 43:1973-81. 2008
    ..Complete resection with adjuvant chemotherapy is the accepted treatment for hepatoblastoma. The aim of this study is to evaluate our results of liver transplantation (LT) for tumors still unresectable after adequate chemotherapy...
  26. ncbi request reprint Presence of multiple bile ducts in the liver graft increases the incidence of biliary complications in pediatric liver transplantation
    Paolo R O Salvalaggio
    Department of Surgery, Children s Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL 60614, USA
    Liver Transpl 11:161-6. 2005
    ..In conclusion, the presence of more than one bile duct in the graft is an independent risk factor for the development of biliary complications after pediatric liver transplantation...
  27. doi request reprint Relationship of proximal renal tubular dysgenesis and fetal liver injury in neonatal hemochromatosis
    Silvana F Bonilla
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614, USA
    Pediatr Res 67:188-93. 2010
    ..Hepatic synthetic failure resulting in insufficient production of AGT to support renal tubular development is the likely mechanism of kidney disease in NH...
  28. ncbi request reprint Recombinant factor VIIa improves coagulopathy caused by liver failure
    Jeffrey B Brown
    Department of Gastroenterology, Hepatology, and Nutrition, Children s Memorial Hospital, Northwestern University, Feinberg School of Medicine, Chicago, IL 60614, USA
    J Pediatr Gastroenterol Nutr 37:268-72. 2003
    ..The benefit of traditional therapies to correct coagulation is often limited and short-lived. Our aim is to identify indications for rFVIIa use and the outcome of treatment in children with liver failure...
  29. doi request reprint Rituximab as therapy for the recurrence of bile salt export pump deficiency after liver transplantation
    Henry C Lin
    Departments of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL
    Liver Transpl 19:1403-10. 2013
    ..Using this approach, we report the successful management of 2 patients with antibody-mediated recurrence of PFIC2 after LT...
  30. ncbi request reprint Simultaneous surgical and interventional radiological approach to treat complicated biliary strictures after pediatric liver transplantation
    Paolo R O Salvalaggio
    Department of Surgery, Children s Memorial Hospital, Northwestern University Feinberg School of Medicine, 700 W Fullerton Street, Chicago, IL 60614, USA
    Pediatr Transplant 8:513-6. 2004
    ..We conclude that an aggressive combined surgical and radiologic approach can avoid retransplantation in patients with complicated post-transplant biliary strictures...
  31. ncbi request reprint Neonatal liver disease
    Karan McBride Emerick
    Division of Gastroenterology, Hepatology, and Nutrition, Children s Memorial Hospital, Northwestern University School of Medicine, Chicago, IL, USA
    Pediatr Ann 35:280-6. 2006
    ....
  32. doi request reprint Regression of severe fibrotic liver disease in 2 children with neonatal hemochromatosis
    Udeme D Ekong
    Departments of Pediatrics, Children s Memorial Hospital, Northwestern University, Chicago, IL 60614, USA
    J Pediatr Gastroenterol Nutr 46:329-33. 2008
  33. ncbi request reprint Partial external biliary diversion for intractable pruritus and xanthomas in Alagille syndrome
    Karan M Emerick
    Department of Pediatrics, Children s Memorial Hospital, Northwestern University Medical School, Chicago, IL 60614, USA
    Hepatology 35:1501-6. 2002
    ..PEBD should be considered as a therapeutic option for these patients before referral for liver transplantation because of morbid complications...
  34. doi request reprint Outcome of pregnancies at risk for neonatal hemochromatosis is improved by treatment with high-dose intravenous immunoglobulin
    Peter F Whitington
    Children s Memorial Hospital, Mail Box 57, 2300 Children s Plaza, Chicago, IL 60614, USA
    Pediatrics 121:e1615-21. 2008
    ..A secondary objective was to use a prospectively collected data set to examine questions of vital interest about neonatal hemochromatosis...
  35. ncbi request reprint Neonatal hemochromatosis: a congenital alloimmune hepatitis
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, Illinois, USA
    Semin Liver Dis 27:243-50. 2007
    ..Given the pathology of the liver and the mechanism of liver injury, NH could best be classified as congenital alloimmune hepatitis...
  36. ncbi request reprint Disparate clinical presentation of neonatal hemochromatosis in twins
    Udeme D Ekong
    Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, Illinois, USA
    Pediatrics 116:e880-4. 2005
    ..They also suggest that affected infants may be missed when using routine clinical testing, which would lead to the apparent rate of recurrence, understating the actual recurrence rate...
  37. ncbi request reprint Improved neurocognitive function after radiologic closure of congenital portosystemic shunts
    Yasemen Eroglu
    Department of Pediatrics, The Feinberg School of Medicine at Northwestern University, Chicago, Illinois, USA
    J Pediatr Gastroenterol Nutr 39:410-7. 2004
  38. ncbi request reprint A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000
    Benjamin L Shneider
    Department of Pediatrics, Mount Sinai Medical Center, New York, NY 10029, Department of Biostatistics, University of Michigan, Ann Arbor, MI, and Department of Pediatrics, Children s Hospital of Philadelphia, PA, USA
    J Pediatr 148:467-474. 2006
    ..To determine the prognostic factors and optimal approaches to the diagnosis and management of biliary atresia, the leading indication for liver transplantation in children...
  39. ncbi request reprint Fetal and infantile hemochromatosis
    Peter F Whitington
    Department of Pediatrics, Northwestern University Feinberg Medical School, Children s Memorial Hospital, Chicago, IL, USA
    Hepatology 43:654-60. 2006
  40. ncbi request reprint Liver transplantation in neonates
    Shikha S Sundaram
    Siragusa Transplantation Center, Children s Memorial Hospital, The Feinberg School of Medicine of Northwestern University, Chicago, IL 60614, USA
    Liver Transpl 9:783-8. 2003
    ..Very little is known about this frontier of transplantation. Our intent is to provide an overview of neonatal OLT using all available data and our experience in the field...
  41. ncbi request reprint Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis
    Cara L Mack
    Departments of Pediatrics and Surgery, Children s Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA
    J Pediatr 142:197-9. 2003
    ..Coagulation factors had returned to normal by one year. The data suggest that portal venous flow is essential for maintaining normal coagulation...
  42. pmc Pancreatic adenocarcinoma in type 2 progressive familial intrahepatic cholestasis
    Lee M Bass
    Northwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, Illinois, USA
    BMC Gastroenterol 10:30. 2010
    ..BSEP disease results from mutations in ABCB11, which encodes the bile salt export pump (BSEP). BSEP disease is associated with an increased risk of hepatobiliary cancer...
  43. ncbi request reprint Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease
    Yu Oyama
    Division of Immunotherapy, Department of Medicine, Northwestern University Medical Center, Chicago, Illinois 60611, USA
    Gastroenterology 128:552-63. 2005
    ..Due to a high morbidity and/or an increase in mortality in refractory cases, a new treatment approach is needed. In theory, maximum immune ablation by autologous hematopoietic stem cell transplantation (HSCT) can induce a remission...
  44. ncbi request reprint Hepatic adenoma in an adolescent with elevated androgen levels
    Maria Triantafyllopoulou
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children s Memorial Hospital, Northwestern University, Chicago, Illinois 60614, USA
    J Pediatr Gastroenterol Nutr 44:640-2. 2007
  45. ncbi request reprint Relative elevations of serum alanine and aspartate aminotransferase in muscular dystrophy
    Rohit Kohli
    Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Children s Memorial Medical Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60614, USA
    J Pediatr Gastroenterol Nutr 41:121-4. 2005
  46. ncbi request reprint Liver transplantation in children
    Peter F Whitington
    The Children s Memorial Hospital and Northwestern University School of Medicine, Chicago, Illinois, USA
    J Pediatr Gastroenterol Nutr 35:S44-50. 2002
  47. ncbi request reprint Molecular basis of neonatal cholestasis
    Karan McBride Emerick
    Division of Gastroenterology, Hepatology and Nutrition, Children s Memorial Hospital, Northwestern University Medical School, Chicago, Illinois, USA
    Pediatr Clin North Am 49:221-35. 2002
    ..The understanding of the functional differences between the immature and mature liver is key to the understanding of neonatal cholestasis...
  48. ncbi request reprint Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats
    Mark S Wainwright
    Department of Pediatrics, The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Stroke 37:524-30. 2006
    ..We used a newborn rat model of hypoxia-ischemia (HI) to test the hypothesis that HI alters acyl-CoA:CoA homeostasis and that this effect can be prevented by treatment with carnitine...
  49. ncbi request reprint Outcomes in pediatric autoimmune hepatitis
    Maria T Greene
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children s Memorial Hospital, Chicago, IL 60614, USA
    Curr Gastroenterol Rep 11:248-51. 2009
    ..In about 10% of patients, treatment fails, requiring alternative therapies and/or liver transplantation as liver disease progresses. Less than 10% of children with autoimmune hepatitis die during 10 years of follow-up...
  50. ncbi request reprint Intracranial vascular abnormalities in patients with Alagille syndrome
    Karan M Emerick
    Division of Gastroenterology, The Children s Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60614, USA
    J Pediatr Gastroenterol Nutr 41:99-107. 2005
    ....
  51. pmc Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation
    Cara L Mack
    Department of Pediatric, The Children s Hospital, University of Colorado Health Science Center, Denver, CO 80218, USA
    Pediatr Res 56:79-87. 2004
    ....
  52. ncbi request reprint Neonatal hemochromatosis
    A S Knisely
    Institute of Liver Studies, King s College Hospital, London, UK
    Gastroenterol Clin North Am 32:877-89, vi-vii. 2003
    ..Immunomodulation during pregnancy at risk appears to lessen the severity of disease...
  53. ncbi request reprint Guideline for the evaluation of cholestatic jaundice in infants: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
    Virginia Moyer
    J Pediatr Gastroenterol Nutr 39:115-28. 2004
    ..These recommendations are a general guideline and are not intended as a substitute for clinical judgment or as a protocol for the care of all patients with this problem...
  54. pmc Growth failure and outcomes in infants with biliary atresia: a report from the Biliary Atresia Research Consortium
    Patricia A DeRusso
    Johns Hopkins School of Medicine and The Johns Hopkins Children s Center, Baltimore, Maryland, USA
    Hepatology 46:1632-8. 2007
    ..The combination of intermediate bilirubin concentrations and poor mean weight z-scores 3 months after HPE was also associated with poor clinical outcome...
  55. ncbi request reprint Subacute nonsuppurative cholangitis (cholangitis lenta) in pediatric liver transplant patients
    Chieh Chung Lin
    Department of Pediatrics, School of Medicine, Taichung Veterans General Hospital, Chung Shan Medical University, Taichung, Taiwan
    J Pediatr Gastroenterol Nutr 45:228-33. 2007
    ....

Research Grants2

  1. Clinical Center--Biliary Atresia Clinical Research Consortium
    Peter Whitington; Fiscal Year: 2007
    ..and #4 To examine the hypothesis that biliary atresia is a viral-induced, immune mediated disease. ..