Research Topics
Species | Sandra WeintraubSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Profiles of decline in activities of daily living in non-Alzheimer dementiaAlissa H Wicklund
Department of Psychiatry and Behavioral Sciences, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, 320 E Superior, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 21:8-13. 2007..The activities of daily living questionnaire may capture aspects of preserved functioning that are not apparent from patients' scores on cognitive tests, especially for those with aphasia...
The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test batterySandra Weintraub
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, 320 E Superior, Searle 11 467, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 23:91-101. 2009....
Cognition assessment using the NIH ToolboxSandra Weintraub
Cognitive Neurology and Alzheimer s Disease Center, Northwestern Feinberg School of Medicine, Chicago, IL, USA
Neurology 80:S54-64. 2013..With a computerized format and national standardization, this battery will provide a "common currency" among researchers for comparisons across a wide range of studies and populations...
The neuropsychological profile of Alzheimer diseaseSandra Weintraub
Cognitive Neurology and Alzheimer s Disease Center CNADC, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Cold Spring Harb Perspect Med 2:a006171. 2012....
Verbal and nonverbal memory in primary progressive aphasia: the Three Words-Three Shapes TestSandra Weintraub
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Behav Neurol 26:67-76. 2013..To investigate cognitive components and mechanisms of learning and memory in primary progressive aphasia (PPA) using a simple clinical measure, the Three Words Three Shapes Test (3W3S)...
A web-based normative calculator for the uniform data set (UDS) neuropsychological test batterySteven D Shirk
Department of Neurology, Massachusetts General Hospital Memory Disorders Unit, 15 Parkman Street, WACC 715, Boston, MA 02114, USA
Alzheimers Res Ther 3:32. 2011..In addition, we aimed to provide an easily accessible method of creating norms for other clinical researchers for their own, unique data sets...
Preservation of reasoning in primary progressive aphasia: further differentiation from Alzheimer's disease and the behavioral presentation of frontotemporal dementiaAlissa H Wicklund
Department of Psychiatry and Behavioral Sciences, Division of Psychology, Cognitive Neurology and Alzheimer s Disease Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Clin Exp Neuropsychol 26:347-55. 2004..In contrast, both AD and FTD subjects were significantly impaired on both measures. These results provide evidence of preserved reasoning in PPA, further differentiating this syndrome from other behaviorally focal dementia syndromes...
The northwestern anagram test: measuring sentence production in primary progressive aphasiaSandra Weintraub
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Cognitive Neurology and Alzheimer s Disease Center, Chicago, Illinois 60611, USA
Am J Alzheimers Dis Other Demen 24:408-16. 2009..The NAT can be used to assess syntax competence when patients cannot be tested with measures that require intact speech production...
Vasectomy in men with primary progressive aphasiaSandra Weintraub
Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Cogn Behav Neurol 19:190-3. 2006..To study the frequency of vasectomy in men with primary progressive aphasia (PPA)...
Altered effective connectivity within the language network in primary progressive aphasiaSreepadma P Sonty
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, Illinois 60611, USA
J Neurosci 27:1334-45. 2007..These results demonstrate for the first time that dysfunctional network interactions (effective connectivity), rather than hypoactivity within individual brain regions, may contribute to the emergence of language deficits seen in PPA...
Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairmentLisa A Bagurdes
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, United States
Neuropsychologia 46:2943-8. 2008..These results suggest a reorganization of the relationships between the limbic system and spatial attention network in healthy aging and MCI...
Alzheimer and frontotemporal pathology in subsets of primary progressive aphasiaMarsel Mesulam
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Ann Neurol 63:709-19. 2008..To identify predictors of Alzheimer's disease (AD) versus frontotemporal lobar degeneration pathology in primary progressive aphasia (PPA), and determine whether the AD pathology is atypically distributed to fit the aphasic phenotype...
Words and objects at the tip of the left temporal lobe in primary progressive aphasiaM Marsel Mesulam
Cognitive Neurology and Alzheimer s Disease Centre, Northwestern University, 320 East Superior Street Feinberg School of Medicine, Chicago, IL 60611, USA
Brain 136:601-18. 2013....
The Spanish translation and adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease CentersAmarilis Acevedo
Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, MRI Building, 2nd Floor, 4300 Alton Road, Miami Beach, FL 33140, USA
Alzheimer Dis Assoc Disord 23:102-9. 2009....
Neurology of anomia in the semantic variant of primary progressive aphasiaMarsel Mesulam
Cognitive Neurology and Alzheimer s Disease Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Brain 132:2553-65. 2009....
Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementiaTamar Gefen
Feinberg School of Medicine, Cognitive Neurology and Alzheimer s Disease Centre, Northwestern University, 320 E Superior Street, Chicago, IL 60611, USA
Brain 135:1554-65. 2012....
Quantitative classification of primary progressive aphasia at early and mild impairment stagesM Marsel Mesulam
Cognitive Neurology and Alzheimer s Disease Centre, Northwestern University, Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA
Brain 135:1537-53. 2012..An emphasis on early diagnosis will promote a better characterization of the disease stages where therapeutic interventions are the most likely to succeed...
Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relativesEmily Rogalski
Neurological Sciences, Rush University Medical Center, 1735 W Harrison Street, Chicago, IL 60612, USA
Arch Neurol 65:244-8. 2008..Although risk factors for Alzheimer disease have been well studied, much less is known about risk factors for primary progressive aphasia (PPA)...
Primary progressive aphasia: relationship between gender and severity of language impairmentEmily Rogalski
Cognitive Neurology and Alzheimer s Disease Center Department of Preventive Medicine, Northwestern University, Chicago, IL, USA
Cogn Behav Neurol 20:38-43. 2007..Comparisons were also made within a group of probable Alzheimer disease (AD) patients to determine whether gender differences were present in the most common form of neurodegenerative dementia...
The mini-mental state examination in behavioral variant frontotemporal dementia and primary progressive aphasiaJason E Osher
Department of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Am J Alzheimers Dis Other Demen 22:468-73. 2007..However, the score may be a more accurate measure of functional impairment in bvFTD due to the influence of their executive function and attentional deficits on MMSE performance...
Covert processing of words and pictures in nonsemantic variants of primary progressive aphasiaEmily Rogalski
Cognitive Neurology and Alzheimer s Disease Center, Department of Preventative Medicine, Northwestern University, Chicago, IL 60612, USA
Alzheimer Dis Assoc Disord 22:343-51. 2008..The boundaries between the semantic and nonsemantic variants are therefore far from rigid...
Association of GSK3B with Alzheimer disease and frontotemporal dementiaBarbara A J Schaffer
Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 2506 Gonda, 695 Charles E Young Dr S, Los Angeles, CA 90095 1761, USA
Arch Neurol 65:1368-74. 2008..As a known tau kinase, GSK3B is a promising candidate gene in the remaining cases of FTD and in AD, for which tau mutations have not been found...
Word list versus story memory in Alzheimer disease and frontotemporal dementiaAlissa H Wicklund
Department of Psychiatry and Behavioral Sciences, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 20:86-92. 2006..The results suggest that patterns of performance on different tests of memory, and, in particular, measures of retention, can be useful in differentiating memory impairment in AD from that of FTD on cognitive testing...
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's diseaseAneta Grudzien
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Feinberg School of Medicine, 320 East Superior Street, Searle 11 453, Chicago, IL 60611, USA
Neurobiol Aging 28:327-35. 2007..These results indicate that cytopathology in the LC is an early event in the age-MCI-AD continuum and that it may be listed among the numerous factors that mediate the emergence of the cognitive changes leading to dementia...
TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer diseaseEileen H Bigio
Cognitive Neurology and Alzheimer Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Acta Neuropathol 120:43-54. 2010..Furthermore, medial temporal TDP-43 pathology is more tightly linked to HS than to clinical phenotype. These findings challenge the current notions about clinicopathologic correlation, especially about the role of multiple pathologies...
ApoE E4 is a susceptibility factor in amnestic but not aphasic dementiasEmily Joy Rogalski
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 25:159-63. 2011..These data show that ε4 polymorphism, which is a well-known risk factor for AD pathology in typical amnestic dementias, has no similar relationship to the clinical syndrome of PPA or its association with AD pathology...
Rate of cognitive change measured by neuropsychologic test performance in 3 distinct dementia syndromesAlissa H Wicklund
Department of Psychiatry and Behavioral Sciences, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 21:S70-8. 2007..The comparison of the rate of decline in FTD and PPA may also reflect the neuroanatomic overlap in these syndromes over time...
When memory does not fail: familiarity-based recognition in mild cognitive impairment and Alzheimer's diseaseCarmen E Westerberg
Northwestern University, Evanston, IL 60208, USA
Neuropsychology 20:193-205. 2006..Neuropathology in hippocampus and entorhinal cortex, known to be present in MCI, presumably disrupted recollection while leaving familiarity-based recognition intact...
Quantitative template for subtyping primary progressive aphasiaMarsel Mesulam
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, Illinois 60611, USA
Arch Neurol 66:1545-51. 2009..The syndrome of primary progressive aphasia (PPA) is diagnosed when a gradual failure of word usage or comprehension emerges as the principal feature of a neurodegenerative disease...
False recognition of incidentally learned pictures and words in primary progressive aphasiaEmily Rogalski
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, IL, USA
Neuropsychologia 45:368-77. 2007..This suggests that the aphasia in PPA patients contributes to their difficulty in selecting among items within a semantic class...
Functional decline associated with polypharmacy and potentially inappropriate medications in community-dwelling older adults with dementiaDenys T Lau
Department of Pharmacy Administration, University of Illinois at Chicago, College of Pharmacy, 60612, USA
Am J Alzheimers Dis Other Demen 26:606-15. 2011..More research is needed to understand which classes of medications have the most deleterious effect on this population...
Concurrent impairments in sleep and memory in amnestic mild cognitive impairmentCarmen E Westerberg
Psychology Department and Interdepartmental Neuroscience Program, Northwestern University, Evanston, Illinois, USA
J Int Neuropsychol Soc 18:490-500. 2012..These results suggest that sleep changes in aMCI patients contribute to memory impairments by interfering with sleep-dependent memory consolidation...
Electrophysiology of object naming in primary progressive aphasiaRobert S Hurley
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, Illinois 60660, USA
J Neurosci 29:15762-9. 2009..N400 analyses can thus help dissect the multiple cognitive mechanisms that contribute to object naming failures in PPA...
Cognitive deficits and reduced insight in primary progressive aphasiaSarah Jane Banks
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Am J Alzheimers Dis Other Demen 23:363-71. 2008..This study has implications for the anatomical network involved in insight and clinical implications in terms of selecting interventions appropriate for individual patients with PPA...
Paradoxical features of word finding difficulty in primary progressive aphasiaRik R Vandenberghe
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, IL, USA
Ann Neurol 57:204-9. 2005..Selection among competing word forms sharing a same semantic field is abnormal in PPA. The semantic interference effect constitutes a positive distinguishing feature between PPA and PRAD...
Differential age-related decline in conflict-driven task-set shielding from emotional versus non-emotional distractersJim M Monti
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, USA
Neuropsychologia 48:1697-706. 2010....
Anatomy of language impairments in primary progressive aphasiaEmily Rogalski
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University NU Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Neurosci 31:3344-50. 2011..Further, these atrophy patterns reveal anatomical correlates of language that could not have been surmised in patients with aphasia resulting from cerebrovascular lesions...
Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairmentAngela L Guillozet
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, IL 60611, USA
Arch Neurol 60:729-36. 2003..Whether a similar relationship exists in normal aging and mild cognitive impairment (MCI), a condition that frequently reflects a preclinical stage of AD, remains unknown...
Syntactic and morphosyntactic processing in stroke-induced and primary progressive aphasiaCynthia K Thompson
Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, USA
Behav Neurol 26:35-54. 2013....
Language and behavior domains enhance the value of the clinical dementia rating scaleDavid S Knopman
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Alzheimers Dement 7:293-9. 2011..The CDRstd does not specifically address language dysfunction or alteration in personality and social behaviors which are prominent in behavioral variant frontotemporal dementia (bvFTD) and primary progressive aphasia (PPA)...
Self-awareness and self-monitoring of cognitive and behavioral deficits in behavioral variant frontotemporal dementia, primary progressive aphasia and probable Alzheimer's diseaseSarah Banks
Northwestern University, Feinberg School of Medicine, Cognitive Neurology and Alzheimer s Disease Center, Chicago, IL, USA
Brain Cogn 67:58-68. 2008..Naming ability, in contrast, was either accurately assessed or underestimated in all groups. Finally, there were no notable differences between self-awareness and self-monitoring, potential explanations for this are examined...
Youthful Memory Capacity in Old Brains: Anatomic and Genetic Clues from the Northwestern SuperAging ProjectEMILY J ROGALSKI
Northwestern University Feinberg School of Medicine, Chicago
J Cogn Neurosci 25:29-36. 2013..They also offer clues to potential biological factors that may promote resistance to age-related involutional changes in the structure and function of the brain...
The Cognitive Change in Women study (CCW): informant ratings of cognitive change but not self-ratings are associated with neuropsychological performance over 3 yearsRebecca Gavett
Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, IL 60611, USA
Alzheimer Dis Assoc Disord 25:305-11. 2011..These results suggest that informants may be sensitive to changes that are not clinically significant but that may represent an incipient trend for decline...
Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuumMarsel Mesulam
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Ann Neurol 55:815-28. 2004..These results show that cytopathology in cortical cholinergic pathways is a very early event in the course of the continuum that leads from advanced age to MCI and AD...
Reducing case ascertainment costs in U.S. population studies of Alzheimer's disease, dementia, and cognitive impairment-Part 2Denis A Evans
Rush Institute on Healthy Aging, Rush University Medical Center, Chicago, IL, USA
Alzheimers Dement 7:110-23. 2011....
The "zoom lens" of focal attention in visual search: changes in aging and Alzheimer's diseaseAlexander Rösler
Cognitives Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, IL, USA
Cortex 41:512-9. 2005..Reduced efficiency of visual search in AD may be contributed to by reduced ability to dynamically adjust the attentional zoom, coupled with the inability to disengage attention from peripheral targets...
Artificial grammar learning in Alzheimer's diseasePaul J Reber
Department of Psychology, Northwestern University, Evanston, Illinois 60201, USA
Cogn Affect Behav Neurosci 3:145-53. 2003..In addition, the nondeclarative memory of the AD patients acquired during AGL appeared to influence their performance on a declarative memory task, suggesting an interaction between this nondeclarative memory task and declarative memory...
Primary progressive aphasia: PPA and the language networkSreepadma P Sonty
Cognitive Neurology and Alzheimer's Disease Center, Chicago, IL, USA
Ann Neurol 53:35-49. 2003..The additional activations in PPA may therefore represent a compensatory spread of language-related neural activity or a failure to suppress activity in areas normally inhibited during language tasks...
Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlationEileen H Bigio
Cognitive Neurology and Alzheimer Disease CenterDepartments of Pathology Psychiatry Neurology Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago Illinois Department of Neuroscience, Mayo Clinic Jacksonville, Jacksonville, Florida, USA
Neuropathology 33:122-33. 2013....
Semantic interference during object naming in agrammatic and logopenic primary progressive aphasia (PPA)Cynthia K Thompson
Department of Communication Sciences and Disorders, Northwestern University, United States
Brain Lang 120:237-50. 2012..These subtle semantic mapping impairments in non-semantic variants of PPA may contribute to the anomia of these patients...
Prion protein codon 129 genotype prevalence is altered in primary progressive aphasiaXiaohong Li
Department of Neurology, Pritzker School of Medicine and Center for Comprehensive Care and Research on Memory Disorders, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Ann Neurol 58:858-64. 2005..However, the strong association between heterozygosity and PPA raises new questions about its cause and the role of PrP in other neurodegenerative diseases...
The core and halo of primary progressive aphasia and semantic dementiaM-Marsel Mesulam
Cognitive Neurology and Alzheimer's Disease Center and Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Ann Neurol 54:S11-4. 2003
Progranulin mutations in primary progressive aphasia: the PPA1 and PPA3 familiesMarsel Mesulam
Cognitive Neurology and Alzheimer s Disease Center and Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Ill 60611, USA
Arch Neurol 64:43-7. 2007..Primary progressive aphasia (PPA) is a language-based dementia characterized by fluent or nonfluent language disorder as its principal feature...
Superior memory and higher cortical volumes in unusually successful cognitive agingTheresa M Harrison
Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Int Neuropsychol Soc 18:1081-5. 2012....
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseGuy M McKhann
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Alzheimers Dement 7:263-9. 2011..Much work lies ahead for validating the biomarker diagnosis of AD dementia...
Depression in Primary Progressive AphasiaJennifer Medina
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
J Geriatr Psychiatry Neurol 20:153-60. 2007..Symptoms of social withdrawal and lack of mental and physical energy were most common, suggesting that patients with PPA should be evaluated for depression so that they may be appropriately treated...
Recall of remote episodic memories can appear deficient because of a gist-based retrieval orientationJohn D Rudoy
Interdepartmental Neuroscience Program, Northwestern University, Evanston, IL 60208, USA
Neuropsychologia 47:938-41. 2009..Deficits in remote episodic recall, and in future-event imagining, must thus be interpreted in light of habitual tendencies toward gist-based retrieval that some amnesic patients may exhibit...
Cerebral hemispheric specialization for spatial attention: spatial distribution of search-related eye fixations in the absence of neglectMark Mapstone
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Neuropsychologia 41:1396-409. 2003..A theoretical model based on the salience of extrapersonal space appears useful for understanding alterations of attentional allocation, particularly after recovery from stroke...
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementiaKatya Rascovsky
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA 19104, USA
Brain 134:2456-77. 2011..Future studies will be needed to establish the reliability and specificity of these revised diagnostic guidelines...
Polypharmacy and potentially inappropriate medication use among community-dwelling elders with dementiaDenys T Lau
Buehler Center on Aging, Health and Society, Northwestern University, Chicago, IL, USA
Alzheimer Dis Assoc Disord 24:56-63. 2010..Ensuring appropriate medication use in this population is clinically important because of the significant risks for institutionalization...
The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathyMarion Hogg
Neurogenetics Laboratory, Mayo Clinic Jacksonville, Jacksonville, Florida, USA
Acta Neuropathol 106:323-36. 2003..In addition, the results of the RD3 and ET3 immunostains clearly explain for the first time the presence of both 3R and 4R tau isoforms in preparations of insoluble tau from some Pick's disease cases...
A clinical trial of bromocriptine for treatment of primary progressive aphasiaDeborah A Reed
Ann Neurol 56:750. 2004
Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiativeRosa Rademakers
Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
Lancet Neurol 6:857-68. 2007..The most common mutation in GRN is Arg493X. We aimed to establish the contribution of this mutation to FTLD and related disorders...
Is adaptation of the word accentuation test of premorbid intelligence necessary for use among older, Spanish-speaking immigrants in the United States?Robert W Schrauf
Department of Linguistics and Applied Language Studies, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
J Int Neuropsychol Soc 12:391-9. 2006..Regression equations are provided for estimating BWM-R and Ravens scores from WAT scores...
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degenerationJennifer Gass
Department of Neuroscience, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA
Hum Mol Genet 15:2988-3001. 2006..Neuropathological examination showed FTLD with ubiquitin-positive cytoplasmic and intranuclear inclusions in all PGRN mutation carriers...
TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD studyKimmo J Hatanpaa
Department of Pathology, University of Texas Southwestern School of Medicine, Dallas, Texas 75390, USA
J Neuropathol Exp Neurol 67:271-9. 2008..Moreover, assessment of abnormalities in both the hippocampus and frontal cortex may be diagnostically important in FTLD-U...
The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease CentersJohn C Morris
Washington University, St Louis, MO 63108, USA
Alzheimer Dis Assoc Disord 20:210-6. 2006..Data obtained with the UDS are submitted to the National Alzheimer's Coordinating Center and represent a unique and valuable source of data to support and stimulate collaborative research...
Serum alpha-tocopherol, concurrent and past vitamin E intake, and mild cognitive impairmentJulie E Dunn
New England Research Institutes, Watertown, MA, USA
Neurology 68:670-6. 2007....
Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directionsKatya Rascovsky
Memory and Aging Center, University of California, San Francisco, CA 94117, USA
Alzheimer Dis Assoc Disord 21:S14-8. 2007..In this article, we discuss the limitations of current diagnostic criteria and propose the establishment of an international consortium to revise diagnostic and research criteria for the behavioral variant of frontotemporal dementia...
