Research Topics
| Lei WangSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer typeLei Wang
Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences, Chicago, IL 60611
Alzheimer Dis Assoc Disord 26:314-21. 2012..The present study was conducted to assess the relationship between CSF Aβ and tau protein levels and longitudinal measures of hippocampal structure in individuals with and without very mild dementia of the Alzheimer type...- Progressive deformation of deep brain nuclei and hippocampal-amygdala formation in schizophreniaLei Wang
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Biol Psychiatry 64:1060-8. 2008..Progressive decreases in cortical gray matter volume have been reported in schizophrenia. However, studies of progressive change in deep brain nuclei and hippocampal-amygdala formation have not yielded consistent findings... - Fully-automated, multi-stage hippocampus mapping in very mild Alzheimer diseaseLei Wang
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Hippocampus 19:541-8. 2009..Some direct comparisons of the two procedures are also presented... - Donepezil treatment and changes in hippocampal structure in very mild Alzheimer diseaseLei Wang
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Arch Neurol 67:99-106. 2010..To compare longitudinal changes in the hippocampal structure in subjects with very mild dementia of the Alzheimer type (DAT) treated with donepezil hydrochloride, untreated subjects with very mild DAT, and controls without dementia... - Alcohol use disorders contribute to hippocampal and subcortical shape differences in schizophreniaMatthew J Smith
Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences, Chicago, IL 60611, USA
Schizophr Res 131:174-83. 2011..However, the neurobiological basis of this co-morbid interaction is unknown. The aim of this study was to determine the relationship of co-morbid alcohol use disorder (AUD) with brain structure abnormalities in schizophrenia patients... - Thalamic morphology in schizophrenia and schizoaffective disorderMatthew J Smith
Departments of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, 446 East Ontario Street, Suite 1000, Chicago, IL 60611, United States
J Psychiatr Res 45:378-85. 2011..In this study, we examine whether individuals with schizoaffective disorder have a pattern of thalamic deformation that is similar or different to the pattern found in individuals with schizophrenia... - Longitudinal progression of frontal and temporal lobe changes in schizophreniaDerin J Cobia
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 446 E Ontario, Suite 7 100, Chicago, IL 60611, USA
Schizophr Res 139:1-6. 2012..Maintenance of neuropsychological performance and clinical stability in the face of changing neuroanatomical structure suggests the involvement of alternative compensatory mechanisms... - Cortical thickness in neuropsychologically near-normal schizophreniaDerin J Cobia
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 446 E Ontario St, Suite 7 100, Chicago, IL 60611, USA
Schizophr Res 133:68-76. 2011..While generally supportive of distinct etiological processes for cognitive subtypes, results provide direction for further examination of additional neuroanatomical differences... - Cognitively normal individuals with AD parents may be at risk for developing aging-related cortical thinning patterns characteristic of ADKatherine Reiter
Department of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60614, USA
Neuroimage 61:525-32. 2012..These results suggest that as AD offspring age, cortical atrophy is more prominent, particularly if the parent with AD is mother or if the AD offspring is female... - Symmetric abnormalities in sulcal patterning in schizophreniaJohn G Csernansky
Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, 446 E Ontario Suite 7 200, Chicago, IL 60611, USA
Neuroimage 43:440-6. 2008..In individuals with schizophrenia, sulcal depth in the left hemisphere was correlated with the severity of impaired performance on tests of working memory and executive function... 
Structural pathology underlying neuroendocrine dysfunction in schizophreniaMorris B Goldman
Northwestern University, Department of Psychiatry, 446 East Ontario, Suite 7 100, Chicago, IL 60611, United States
Behav Brain Res 218:106-13. 2011..The relationship of these findings to the underlying mental illness remains to be established...
Research Grants
- Schizophrenia Data and Software Tool Federation using BIRN InfrastructureLei Wang; Fiscal Year: 2009..Further, the software tools would enable others to study other MR datasets collected from other clinical samples. ..
- Schizophrenia Data and Software Tool Federation using BIRN InfrastructureLei Wang; Fiscal Year: 2010..Further, the software tools would enable others to study other MR datasets collected from other clinical samples. ..