Bruce K Tan

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Variations in antibiotic prescribing of acute rhinosinusitis in United States ambulatory settings
    Stephanie Shintani Smith
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Otolaryngol Head Neck Surg 148:852-9. 2013
  2. pmc Increased expression of factor XIII-A in patients with chronic rhinosinusitis with nasal polyps
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Allergy Clin Immunol 132:584-592.e4. 2013
  3. pmc Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis
    Deepti R Nagarkar
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 132:593-600.e12. 2013
  4. pmc Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps
    Sarah Peterson
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill 60611, USA
    J Allergy Clin Immunol 129:119-27.e1-9. 2012
  5. pmc Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 130:410-20.e5. 2012
  6. pmc Atopic profile of patients failing medical therapy for chronic rhinosinusitis
    Bruce K Tan
    Department of Otolaryngology, Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Int Forum Allergy Rhinol 1:88-94. 2011
  7. pmc Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression
    Kathryn E Hulse
    Division of Allergy Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 131:1075-83, 1083.e1-7. 2013
  8. pmc Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 131:1350-60. 2013
  9. pmc Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Respir Crit Care Med 187:49-57. 2013
  10. ncbi request reprint Effect of symptom-based risk stratification on the costs of managing patients with chronic rhinosinusitis symptoms
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
    Int Forum Allergy Rhinol 3:933-40. 2013

Collaborators

Detail Information

Publications26

  1. doi request reprint Variations in antibiotic prescribing of acute rhinosinusitis in United States ambulatory settings
    Stephanie Shintani Smith
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Otolaryngol Head Neck Surg 148:852-9. 2013
    ..To identify variations in antibiotic treatment of acute rhinosinusitis (ARS) on a national level...
  2. pmc Increased expression of factor XIII-A in patients with chronic rhinosinusitis with nasal polyps
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Allergy Clin Immunol 132:584-592.e4. 2013
    ..Although the coagulation cascade plays a critical role in fibrin clot formation at extravascular sites, the expression and role of coagulation factors in NP remain unclear...
  3. pmc Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis
    Deepti R Nagarkar
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 132:593-600.e12. 2013
    ..Although increased TSLP mRNA levels have been found in nasal polyps (NPs), expression of TSLP protein and its function in patients with chronic rhinosinusitis (CRS) have not been fully explored...
  4. pmc Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps
    Sarah Peterson
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill 60611, USA
    J Allergy Clin Immunol 129:119-27.e1-9. 2012
    ..CCL18 is thought to be involved in T(H)2-related inflammatory diseases, including asthma and atopic dermatitis...
  5. pmc Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 130:410-20.e5. 2012
    ..Although chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by T(H)2 inflammation, the role of mast cells is poorly understood...
  6. pmc Atopic profile of patients failing medical therapy for chronic rhinosinusitis
    Bruce K Tan
    Department of Otolaryngology, Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Int Forum Allergy Rhinol 1:88-94. 2011
    ..The objective of this research was to analyze the frequency and distribution of allergen sensitivity in patients failing medical therapy for CRSwNP and CRSsNP in comparison to rhinitis patients without CRS and the general population...
  7. pmc Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression
    Kathryn E Hulse
    Division of Allergy Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 131:1075-83, 1083.e1-7. 2013
    ..Despite the high prevalence and morbidity of chronic rhinosinusitis (CRS), little is known about the mechanisms that underlie its pathogenesis. Recent studies have suggested that B cells might play an important role in CRS...
  8. pmc Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 131:1350-60. 2013
    ..Chronic rhinosinusitis (CRS) is a prevalent condition with underexplored risk factors...
  9. pmc Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression
    Tetsuji Takabayashi
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Respir Crit Care Med 187:49-57. 2013
    ..Nasal polyps (NPs) are characterized by intense edema or formation of pseudocysts filled with plasma proteins, mainly albumin. However, the mechanisms underlying NP retention of plasma proteins in their submucosa remain unclear...
  10. ncbi request reprint Effect of symptom-based risk stratification on the costs of managing patients with chronic rhinosinusitis symptoms
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
    Int Forum Allergy Rhinol 3:933-40. 2013
    ....
  11. pmc Association between severity of asthma and degree of chronic rhinosinusitis
    David C Lin
    Medical School class, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Rhinol Allergy 25:205-8. 2011
    ..There is a clinical association between asthma and chronic rhinosinusitis (CRS). This study was designed to determine whether severity of coexistent asthma affects the clinical presentation of CRS...
  12. doi request reprint Establishing a threshold for surgery in recurrent acute rhinosinusitis: a productivity-based analysis
    Randy Leung
    Department of Otolaryngology Head and Neck Surgery, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Otolaryngol Head Neck Surg 146:829-33. 2012
    ..However, it is unclear when one therapy should be recommended over the other. This study seeks to identify a threshold number of infections where the morbidity of surgery is offset by the morbidity of RARS...
  13. doi request reprint Osteomeatal complex obstruction is not associated with adjacent sinus disease in chronic rhinosinusitis with polyps
    Randy M Leung
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Rhinol Allergy 25:401-3. 2011
    ..This is a follow-up and expanded series of a previous pilot study from our group...
  14. doi request reprint A randomized trial examining the effect of pretreatment point-of-care computed tomography imaging on the management of patients with chronic rhinosinusitis symptoms
    Bruce K Tan
    Department of Otolaryngology, Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Int Forum Allergy Rhinol 1:229-34. 2011
    ..The objective of this research was to prospectively evaluate 2 algorithms for the initial management of patients with symptoms of CRS who manifest a normal nasal endoscopic examination...
  15. pmc Identifying clinical symptoms for improving the symptomatic diagnosis of chronic rhinosinusitis
    Wayne D Hsueh
    Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int Forum Allergy Rhinol 3:307-14. 2013
    ....
  16. pmc Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps
    Julie A Poposki
    Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 128:73-81.e4. 2011
    ..The pathogenesis of CRS remains controversial, but it has been associated with the accumulation of various immune and inflammatory cells in sinus tissue...
  17. pmc B-lymphocyte lineage cells and the respiratory system
    Atsushi Kato
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 131:933-57; quiz 958. 2013
    ..Antigen exposure in the upper or lower airways can also drive expansion of B-lineage cells in the airway mucosal tissue and lead to the formation of inducible lymphoid follicles or aggregates that can mediate local immunity or disease...
  18. doi request reprint Factors associated with computed tomography status in patients presenting with a history of chronic rhinosinusitis
    Leah J Abrass
    Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Int Forum Allergy Rhinol 1:178-82. 2011
    ..However, patients suspected to have CRS based on a positive history but negative endoscopies remain a diagnostic challenge. We investigated the utility of point of care computed tomography (POC-CT) in resolving this issue...
  19. pmc Perspectives on the etiology of chronic rhinosinusitis
    Bruce K Tan
    Department of Otolaryngology, Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Curr Opin Otolaryngol Head Neck Surg 18:21-6. 2010
    ..This article reviews recent insights surrounding the etiology and pathogenesis of chronic rhinosinusitis. In particular, we highlight the increasing recognition of host-mediated mechanisms in driving mucosal inflammation...
  20. doi request reprint Postoperative prevention and treatment of complications after sinus surgery
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, 676 North Street Clair, Suite 1325, Chicago, IL 60611, USA
    Otolaryngol Clin North Am 43:769-79. 2010
    ..This article highlights currently available data for postsurgical management strategies and briefly discusses additional techniques and tools under development for managing these complications...
  21. doi request reprint Endoscopic sinus surgery in the management of nasal obstruction
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, MD 21287, USA
    Otolaryngol Clin North Am 42:227-40, vii. 2009
    ..Additionally, advances in airflow modeling that may enable improved preoperative planning for the relief of nasal obstruction after FESS are discussed...
  22. doi request reprint Upfront computed tomography scanning is more cost-beneficial than empiric medical therapy in the initial management of chronic rhinosinusitis
    Randy Leung
    Department of Otolaryngology Head and Neck Surgery, Northwestern Memorial Hospital, Northwestern University, Chicago, IL 60611, USA
    Int Forum Allergy Rhinol 1:471-80. 2011
    ..The objective of this work was to determine whether upfront CT scanning is more cost-beneficial than empiric medical therapy for patients presenting with CRS symptoms but negative endoscopic findings...
  23. pmc Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polyps
    Bruce K Tan
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Allergy Clin Immunol 128:1198-1206.e1. 2011
    ..Because high levels of BAFF are associated with autoimmune diseases, we assessed for evidence of autoimmunity in patients with CRS...
  24. pmc Olfactory input is critical for sustaining odor quality codes in human orbitofrontal cortex
    Keng Nei Wu
    Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Nat Neurosci 15:1313-9. 2012
    ..Our findings suggest that transient changes in these key olfactory brain regions are instrumental in sustaining odor perception integrity in the wake of disrupted sensory input...
  25. pmc The association of premorbid diseases with chronic rhinosinusitis with and without polyps
    Kent Lam
    aDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois bCenter for Health Research, Geisinger Health System, Danville, Pennsylvania, USA
    Curr Opin Otolaryngol Head Neck Surg 22:231-41. 2014
    ....
  26. doi request reprint Comparison of nasal sprays and irrigations in the delivery of topical agents to the olfactory mucosa
    Kent Lam
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, U S A
    Laryngoscope 123:2950-7. 2013
    ..The purpose of this study was to compare the distribution of nasal irrigations to sprays within the olfactory cleft...