Tatyana M Svitkina

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Mechanism of filopodia initiation by reorganization of a dendritic network
    Tatyana M Svitkina
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Cell Biol 160:409-21. 2003
  2. pmc Ena/VASP proteins have an anti-capping independent function in filopodia formation
    Derek A Applewhite
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Mol Biol Cell 18:2579-91. 2007
  3. ncbi request reprint Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end
    Marisan R Mejillano
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Cell 118:363-73. 2004
  4. pmc Visualization of the intracellular behavior of HIV in living cells
    David McDonald
    Dept of Microbiology and Immunology, University of Illinois, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    J Cell Biol 159:441-52. 2002
  5. ncbi request reprint Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility
    James E Bear
    Massachusetts Institute of Technology, Department of Biology, Cambridge 02139, USA
    Cell 109:509-21. 2002
  6. pmc Orientational order of the lamellipodial actin network as demonstrated in living motile cells
    Alexander B Verkhovsky
    Laboratory of Cell Biophysics and Biomechanics, Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland
    Mol Biol Cell 14:4667-75. 2003
  7. ncbi request reprint Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1
    Cecile Lebrand
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuron 42:37-49. 2004
  8. ncbi request reprint A Rickettsia WASP-like protein activates the Arp2/3 complex and mediates actin-based motility
    Robert L Jeng
    Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA
    Cell Microbiol 6:761-9. 2004
  9. pmc Mammalian CARMIL inhibits actin filament capping by capping protein
    Changsong Yang
    Biology Department, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Cell 9:209-21. 2005

Collaborators

Detail Information

Publications9

  1. pmc Mechanism of filopodia initiation by reorganization of a dendritic network
    Tatyana M Svitkina
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Cell Biol 160:409-21. 2003
    ....
  2. pmc Ena/VASP proteins have an anti-capping independent function in filopodia formation
    Derek A Applewhite
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Mol Biol Cell 18:2579-91. 2007
    ..Furthermore, the EVH1 domain, together with the GAB motif in the EVH2 domain, helps to maintain Ena/VASP at the growing barbed ends...
  3. ncbi request reprint Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end
    Marisan R Mejillano
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Cell 118:363-73. 2004
    ....
  4. pmc Visualization of the intracellular behavior of HIV in living cells
    David McDonald
    Dept of Microbiology and Immunology, University of Illinois, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    J Cell Biol 159:441-52. 2002
    ..Based on these observations, we propose that HIV uses dynein and the microtubule network to facilitate the delivery of the viral genome to the nucleus of the cell during early postentry steps of the HIV life cycle...
  5. ncbi request reprint Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility
    James E Bear
    Massachusetts Institute of Technology, Department of Biology, Cambridge 02139, USA
    Cell 109:509-21. 2002
    ..We conclude that Ena/VASP regulates cell motility by controlling the geometry of actin filament networks within lamellipodia...
  6. pmc Orientational order of the lamellipodial actin network as demonstrated in living motile cells
    Alexander B Verkhovsky
    Laboratory of Cell Biophysics and Biomechanics, Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland
    Mol Biol Cell 14:4667-75. 2003
    ..We infer that the light microscopic meshwork reflects the orientational order of actin filaments which, in turn, is related to their branching angle...
  7. ncbi request reprint Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1
    Cecile Lebrand
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuron 42:37-49. 2004
    ..We propose that Ena/VASP proteins control filopodial dynamics in neurons by remodeling the actin network in response to guidance cues...
  8. ncbi request reprint A Rickettsia WASP-like protein activates the Arp2/3 complex and mediates actin-based motility
    Robert L Jeng
    Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA
    Cell Microbiol 6:761-9. 2004
    ..We propose that additional Rickettsia or host factors reorganize the Y-branched networks into parallel arrays in a manner similar to a recently proposed model of filopodia formation...
  9. pmc Mammalian CARMIL inhibits actin filament capping by capping protein
    Changsong Yang
    Biology Department, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Cell 9:209-21. 2005
    ..This phenotype is reversed by full-length mCARMIL but not mCARMIL lacking the domain that binds CP. Thus, mCARMIL is a key regulator of CP and has profound effects on cell behavior...