Research Topics
| Neil J StoneSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardio (GISSI)-Prevenzione Trial on fish oil and vitamin E supplementation in myocardial infarction survivorsN J Stone
Northwestern University School of Medicine, 211 E Chicago Avenue STE 1050, Chicago, Illinois 60611, USA
Curr Cardiol Rep 2:445-51. 2000....
Recent National Cholesterol Education Program Adult Treatment Panel III update: adjustments and optionsNeil J Stone
Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Cardiol 96:53E-59E. 2005..8) Continue to treat those at low risk in similar fashion as before. This update is to inform current physician judgment in this area. Further clinical trial data that may modify or extend these recommendations are eagerly awaited...
Nonpharmacologic management of mixed dyslipidemia associated with diabetes mellitus and the metabolic syndrome: a review of the evidenceNeil J Stone
Feinberg School of Medicine, Northwestern University, Northwestern Memorial Hospital, Chicago, Illinois 60093, USA
Am J Cardiol 102:14L-18L. 2008..The aim of this article is to review evidence to support this approach. To achieve all recommended lipid goals in clinical practice, lifestyle intervention is likely to be adjunctive to pharmacotherapy...
Successful control of dyslipidemia in patients with metabolic syndrome: focus on lifestyle changesNeil J Stone
Department of Medicine, Section of Cardiology, Feinberg School of Medicine, Northwestern University Chicago, Illinois 60611, USA
Clin Cornerstone 8:S15-20. 2006....
Focus on lifestyle change and the metabolic syndromeNeil J Stone
Feinberg School of Medicine, Northwestern University, 211 East Chicago Avenue, Suite 1050, Chicago, IL 60611, USA
Endocrinol Metab Clin North Am 33:493-508, v-vi. 2004..The article also provides practical strategies...
Approach to treatment of the patient with metabolic syndrome: lifestyle therapyNeil J Stone
Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Cardiol 96:15E-21E. 2005..We offer a practical approach with a focus that embraces not only patients, but also physicians and healthcare professionals as well as the larger healthcare system...
Effects of dietary modification to reduce vascular risks and treatment of obesityNeil J Stone
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Cardiol Clin 21:415-33. 2003..Emphasis on foods rich in n-3 fatty acids shows promise for reducing cardiovascular outcomes, particularly sudden death...
Are statins indicated for the primary prevention of coronary heart disease in octogenarians? protagonist viewpointNeil J Stone
The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Geriatr Cardiol 12:351-6. 2003..In this regard, a low high-density lipoprotein cholesterol level, high-sensitivity C-reactive protein level, and subclinical measures of atherosclerosis may be particularly useful...
The optimal dietary strategy to manage risk associated with various dyslipidemiasN J Stone
1356 Edgewood Lane, Winnetka, IL 60093, USA
Curr Cardiol Rep 3:391-400. 2001....
Therapeutic lifestyle change and Adult Treatment Panel III: evidence then and nowNeil J Stone
Department of Medicine, Feinberg School of Medicine of Northwestern University, 211 East Chicago Avenue, Suite 1050, Chicago, IL 60611, USA
Curr Atheroscler Rep 4:433-43. 2002....
Relation of body mass index to late survival after valvular heart surgeryMuthiah Vaduganathan
Divisions of Cardiac Surgery and Cardiology, Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Am J Cardiol 110:1667-78. 2012..Very lean patients undergoing valve surgery are at a greater hazard for mortality and might require more rigorous preoperative candidate screening and closer postoperative monitoring...
Midterm benefits of preoperative statin therapy in patients undergoing isolated valve surgeryMuthiah Vaduganathan
Division of Cardiothoracic Surgery, Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 2908, USA
Ann Thorac Surg 93:1881-7. 2012..The midterm effects of preoperative statin therapy in the setting of valvular heart surgery are presently unclear...
Treatment of metabolic syndromeArati Wagh
Departments of Endocrinology and Cardiology, Feinberg School of Medicine, Northwestern University, 211 E Chicago Avenue, 1050 Chicago, IL 60611, USA
Expert Rev Cardiovasc Ther 2:213-28. 2004..Although metformin is shown to be useful with polycystic ovary syndrome, the data supporting drug therapy for the other syndromes is less convincing. More robust studies are needed before any firm recommendations can be made...
Perioperative statin therapy reduces mortality in normolipidemic patients undergoing cardiac surgeryMuthiah Vaduganathan
Division of Cardiac Surgery, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine and Northwestern Memorial Hospital, Chicago, IL, USA
J Thorac Cardiovasc Surg 140:1018-27. 2010..Recent data have suggested that statins improve early survival and cardiovascular outcomes after coronary artery bypass graft surgery. The effectiveness of statin therapy in normolipidemic cardiac surgery patients is as yet unclear...
Clinical status and cardiovascular risk profile of adults with a history of juvenile dermatomyositisMicah J Eimer
Division of Cardiology, University of Chicago, Chicago, IL, USA
J Pediatr 159:795-801. 2011..A pilot study of adults who had onset of juvenile dermatomyositis (JDM) in childhood, before current therapeutic approaches, to characterize JDM symptoms and subclinical cardiovascular disease...
Evidence-based treatment of lipids in the elderlyMicah J Eimer
Department of Medicine/Division of Cardiology, Feinberg School of Medicine, Northwestern University, 211 E. Chicago Avenue, Chicago, IL 60611, USA
Curr Atheroscler Rep 6:388-97. 2004..We also consider negative aspects, risks, and costs of such therapy...
Statins as cardioprotective agentsJulie R Piskur
Department of Medicine, Northwestern University, Evanston, Illinois, USA
Am J Manag Care 8:25-9. 2002
Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valveN M Rajamannan
Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Heart 91:806-10. 2005....
Commentary. Secondary causes of hypertriglyceridemia and pancreatitisArati Wagh
Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Clin Chim Acta 332:21. 2003
Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valveNalini M Rajamannan
Division of Cardiology, Department of Medicine, Northwestern University Medical School, Chicago, Ill 60611, USA
Circulation 105:2660-5. 2002..We hypothesized that atherosclerosis and early bone matrix expression in the aortic valve occurs secondary to experimental hypercholesterolemia and that treatment with atorvastatin modifies this transformation...
Long-term survival of childhood coronary artery disease in a patient severely affected with familial hypercholesterolemiaChristopher Sibley
Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Am J Cardiol 94:699-700. 2004..This is heretofore unreported in phenotypically homozygous patients with familial hypercholesterolemia in the era before statin drugs, low-density lipoprotein apheresis, or their combination...
Improvement in the function of hibernating myocardium in a patient with heart failure due to coronary artery disease receiving high-dose simvastatinMihai Gheorghiade
Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Ital Heart J 5:160-2. 2004..We speculate that high-dose statin therapy had a significant role in improving the ventricular function in our patient by improving the endothelial flow. This hypothesis is presently being tested in a larger prospective trial...
Emphasizing statin safety in the hospitalized patient: a reviewAlicia Leung
Division of Hospital Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Med 125:845-53. 2012..We review the essentials of statin metabolism and drug-drug interactions to provide the hospital physician with information to minimize potentially serious adverse statin effects...
Obesity paradox in amputation risk among nonelderly diabetic menMin Woong Sohn
Center for Management of Complex Chronic Care, Hines Veterans Affairs Hospital, Hines, Illinois, USA
Obesity (Silver Spring) 20:460-2. 2012..More research is needed to better understand pathophysiological mechanisms that may explain the paradoxical association between obesity and lower-extremity amputation (LEA) risk...
Metabolic syndrome managementNeil J Stone
Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Expert Opin Pharmacother 8:2059-75. 2007..If successful, comprehensive management of the metabolic syndrome promises to delay or prevent the development of coronary heart disease and Type 2 diabetes mellitus...
Current drug treatments for lipid managementNeil J Stone
Feinberg School of Medicine, Northwestern University, Chicago, USA
Manag Care 11:4-9. 2002
Effect of amiodarone-induced hyperthyroidism on left ventricular outflow obstruction after septal myectomy for hypertrophic cardiomyopathySean D Pokorney
Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Am J Cardiol 106:1670-2. 2010..In conclusion, recognition of this diagnosis in patients with recurrence of outflow obstruction by symptoms and cardiac imaging after septal myectomy may avoid unnecessary repeat surgical intervention...
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association ScienThomas A Pearson
Circulation 106:388-91. 2002
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Circulation 110:227-39. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy...
Goals of statin therapy: three viewpoints. 2002Gillbert R Thompson
Atheroscler Suppl 5:107-14. 2004
A summary of implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Arterioscler Thromb Vasc Biol 24:1329-30. 2004
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III GuidelinesScott M Grundy
J Am Coll Cardiol 44:720-32. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy...
Application of recent definitions of the metabolic syndrome to survey data from the National Cholesterol Education Program Evaluation Project Utilizing Novel E-Technology (NEPTUNE II)Prakash C Deedwania
University of California San Francisco, School of Medicine, Fresno, CA 93703, USA
J Cardiometab Syndr 1:295-300. 2006..The metabolic syndrome is common in patients receiving lipid-lowering therapy in an office-based setting. Three recent definitions resulted in similar estimates of its prevalence...
Is it time for a cardiovascular primary prevention trial in the elderly?Jennifer G Robinson
Lipid Research Clinic, Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
Stroke 38:441-50. 2007..However, few data are available for primary prevention of cardiovascular disease in those aged > or =70 years...
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Arterioscler Thromb Vasc Biol 24:e149-61. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy...
Identifying patients for aggressive cholesterol lowering: the risk curve conceptJennifer G Robinson
Am J Cardiol 98:1405-8. 2006....
Evidence-based guidelines for cardiovascular disease prevention in women: 2007 updateLori Mosca
Columbia University, USA
Circulation 115:1481-501. 2007
Therapy and clinical trialsNeil J Stone
Curr Opin Lipidol 17:199-201. 2006
American Heart Association guide for improving cardiovascular health at the community level: a statement for public health practitioners, healthcare providers, and health policy makers from the American Heart Association Expert Panel on Population and PreThomas A Pearson
Circulation 107:645-51. 2003
Hyperlipidemia and cardiovascular diseaseNeil J Stone
Curr Opin Lipidol 14:223-5. 2003
Antiatherosclerotic and antithrombotic effects of omega-3 fatty acidsJennifer G Robinson
Department of Epidemiology, University of Iowa, Iowa City, Iowa 52242, USA
Am J Cardiol 98:39i-49i. 2006..Ongoing clinical trials may clarify the non-antiarrhythmic benefits of omega-3 fatty acid supplementation...
Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes AssociationJohn B Buse
University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Diabetes Care 30:162-72. 2007..This statement will attempt to harmonize the recommendations of both organizations where possible but will recognize areas in which AHA and ADA recommendations differ...
Stopping statinsNeil J Stone
Circulation 110:2280-2. 2004
Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes AssociationJohn B Buse
University of North Carolina, USA
Circulation 115:114-26. 2007..This statement will attempt to harmonize the recommendations of both organizations where possible but will recognize areas in which AHA and ADA recommendations differ...
Hyperlipidaemia and cardiovascular diseaseNeil J Stone
Curr Opin Lipidol 15:707-9. 2004
Evidence-based guidelines for cardiovascular disease prevention in women: 2007 updateLori Mosca
J Am Coll Cardiol 49:1230-50. 2007
