Research Topics
| William SmallSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomyWilliam Small
Department of Radiation Oncology, The Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
Brachytherapy 11:58-67. 2012..To develop recommendations for the use of adjuvant vaginal cuff brachytherapy after hysterectomy and update previous American Brachytherapy Society (ABS) guidelines...
Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy in postoperative treatment of endometrial and cervical cancerWilliam Small
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
Int J Radiat Oncol Biol Phys 71:428-34. 2008..To develop an atlas of the clinical target volume (CTV) definitions for postoperative radiotherapy of endometrial and cervical cancer to be used for planning pelvic intensity-modulated radiotherapy...
Full-dose gemcitabine with concurrent radiation therapy in patients with nonmetastatic pancreatic cancer: a multicenter phase II trialWilliam Small
Robert H Lurie Comprehensive Cancer Center of Northwestern University, 251 East Huron St, LC 178, Chicago, IL 60611, USA
J Clin Oncol 26:942-7. 2008..This study assessed safety and efficacy of full-dose gemcitabine administered before and during concurrent three-dimensional conformal radiation (3D-CRT) in patients with nonmetastatic pancreatic cancer...
Extended-field irradiation and intracavitary brachytherapy combined with cisplatin and amifostine for cervical cancer with positive para-aortic or high common iliac lymph nodes: results of arm II of Radiation Therapy Oncology Group (RTOG) 0116William Small
The Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
Int J Gynecol Cancer 21:1266-75. 2011..This report presents the results of part 2...
Practice patterns of radiotherapy in endometrial cancer among member groups of the gynecologic cancer intergroupWilliam Small
RTOG, Philadelphia, PA, USA
Int J Gynecol Cancer 19:395-9. 2009..To describe radiotherapeutic practice of the treatment of endometrial cancer in members of the Gynecologic Cancer Intergroup (GCIG)...
A prospective trial comparing lymphangiogram, cross-sectional imaging, and positron emission tomography scan in the detection of lymph node metastasis in locally advanced cervical cancerWilliam Small
Department of Radiation Oncology, The Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA
Am J Clin Oncol 33:89-93. 2010....
Phase II trial of full-dose gemcitabine and bevacizumab in combination with attenuated three-dimensional conformal radiotherapy in patients with localized pancreatic cancerWilliam Small
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois 60611, USA
Int J Radiat Oncol Biol Phys 80:476-82. 2011..To evaluate response rate, survival, and toxicity in patients with nonmetastatic pancreatic cancer treated with gemcitabine, bevacizumab, and radiotherapy...
Should uterine tandem applicators ever be placed without ultrasound guidance? No: a brief report and review of the literatureWilliam Small
Department of Radiation Oncology, The Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
Int J Gynecol Cancer 21:941-4. 2011..Uterine perforation by the tandem is common and often undetected by orthogonal radiographs. The role of ultrasound in guiding tandem placement remains controversial...
Extended-field irradiation and intracavitary brachytherapy combined with cisplatin chemotherapy for cervical cancer with positive para-aortic or high common iliac lymph nodes: results of ARM 1 of RTOG 0116William Small
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center of Northwestern University, 251 E Huron Street, Chicago, IL 60611, USA
Int J Radiat Oncol Biol Phys 68:1081-7. 2007..This manuscript reports the results of Part 1...
FIGO stage IIIC endometrial carcinoma: prognostic factors and outcomesAnna V Hoekstra
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Gynecol Oncol 114:273-8. 2009..Investigate the clinicopathologic characteristics, nodal distribution, and postoperative treatment of patients with FIGO stage IIIC endometrial carcinoma and determine patterns of recurrence and survival...
Use of molecular imaging to predict clinical outcome in patients with rectal cancer after preoperative chemotherapy and radiationAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 74:55-9. 2009....
Inoperable pancreatic cancer: standard of careKari B Wisinski
Division of Hematology Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
Oncology (Williston Park) 21:1558-64; discussion 1565, 1570-2. 2007..Future investigations need to focus on understanding the molecular nature of this malignancy, with the goal of developing interventions based on this knowledge...
A multi-institutional phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinomaMark S Talamonti
Division of Surgical Oncology, Feinberg School of Medicine, Northwestern University, 201 E Huron, Galter 10 105, Chicago, Illinois 60611, USA
Ann Surg Oncol 13:150-8. 2006..We report the results of a multi-institutional phase II trial that used preoperative full-dose gemcitabine and radiotherapy for patients with potentially resectable pancreatic carcinoma...
Multi-institutional review of repeat irradiation of chest wall and breast for recurrent breast cancerAndrew O Wahl
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Int J Radiat Oncol Biol Phys 70:477-84. 2008..To review the toxicity and clinical outcomes for patients who underwent repeat chest wall or breast irradiation (RT) after local recurrence...
Efficacy and patterns of failure for locally advanced cancer of the cervix treated with celebrex (celecoxib) and chemoradiotherapy in RTOG 0128David K Gaffney
Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, UT 84132, USA
Int J Radiat Oncol Biol Phys 69:111-7. 2007..To determine the efficacy and patterns of initial failure for oral celecoxib, intravenous cisplatin, and 5-fluorouracil and concurrent pelvic radiotherapy in patients with locally advanced cancer of the cervix...
Cytoprotection/radioprotection with amifostine: potential role in cervical cancer and early findings in the Radiation Therapy Oncology Group C-0116 trialWilliam Small
Division of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
Semin Oncol 30:68-71. 2003..The trial should provide important information on the potential for adjunctive amifostine use in chemoradiation therapy for cervical cancer...
Preoperative chemoradiation for rectal cancer: results of multimodality management and analysis of prognostic factorsAnand T Shivnani
Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Am J Surg 193:389-93; discussion 393-4. 2007..Our goals were to examine the impact of neoadjuvant chemoradiation for rectal cancer on surgical outcomes and to determine prognostic factors predicting improved survival...
The role of adjuvant radiation in endometrial cancerVirginia Diavolitsis
Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA
Oncology (Williston Park) 23:342-9. 2009..Chemotherapy alone in advanced-stage patients is a consideration, given the results of the Gynecologic Oncology Group (GOG)-122 trial...
Change in creatinine clearance over time following upper abdominal irradiation: a dose-volume histogram multivariate analysisVirginia M Diavolitsis
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
Am J Clin Oncol 34:53-7. 2011..To investigate the change in creatinine clearance (CrCl) over time following upper abdominal radiation utilizing a dose-volume histogram (DVH) multivariate analysis...
Brain metastasis in gestational trophoblastic neoplasia: an updateNikki L Neubauer
Departments of Obstetrics and Gynecology and of Radiation Oncology, John I Brewer Trophoblastic Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
J Reprod Med 57:288-92. 2012..To update the treatment of brain metastases in gestational trophoblastic neoplasia (GTN) at the Brewer Trophoblastic Disease Center, comparing treatment and outcomes from 1995-2009 with those from 1962-1994...
Prospective measurements of intra-abdominal volume and pulmonary function after repair of massive ventral hernias with the components separation techniqueSonya P Agnew
Division of Plastic and Reconstructive Surgery, Department of Radiation Oncology, Northwestern University, Evanston, IL, USA
Ann Surg 251:981-8. 2010..To assess the effect of components separation on abdominal volume and pulmonary function after repair of hernias with loss of domain...
Change in the growth rate of localized pancreatic adenocarcinoma in response to gemcitabine, bevacizumab, and radiation therapy on MDCTPedram Rezai
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Int J Radiat Oncol Biol Phys 81:452-9. 2011..1 guideline...
Potential for use of amifostine in cervical cancerWilliam Small
Department of Clinical Radiology, Division of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
Semin Oncol 29:34-7. 2002....
The current status of combined radiotherapy and chemotherapy for locally advanced or resected pancreas cancerMary F Mulcahy
Department of Radiology, Division of Hematology Oncology and the Division of Radiation Oncology, Northwestern University, Robert H Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA
J Natl Compr Canc Netw 3:637-42. 2005..Recognizing which patients are likely to benefit from combination therapy or systemic therapy alone is a subject of future and ongoing clinical trials...
The potential role of amifostine in the treatment of carcinoma of the uterine cervix: a reviewWilliam Small
Division of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
Semin Radiat Oncol 12:68-74. 2002..Although highly effective, radiotherapy can be associated with significant complications. Amifostine has been shown to be an effective radioprotector in head and neck malignancies. Preliminary evidence suggests a role in cervical cancer...
American Brachytherapy Society consensus guidelines for locally advanced carcinoma of the cervix. Part III: low-dose-rate and pulsed-dose-rate brachytherapyLarissa J Lee
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
Brachytherapy 11:53-7. 2012..To develop a guideline for quality practice of low-dose-rate (LDR) and pulsed-dose-rate (PDR) brachytherapy for locally advanced cervical cancer...
American Brachytherapy Society survey regarding practice patterns of postoperative irradiation for endometrial cancer: current status of vaginal brachytherapyWilliam Small
Division of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
Int J Radiat Oncol Biol Phys 63:1502-7. 2005..To survey the current postoperative recommendations for radiotherapy (RT) in patients with endometrial cancer, with an emphasis on vaginal brachytherapy (VBT)...
ACR Appropriateness Criteria® definitive therapy for early-stage cervical cancerWilliam Small
The Robert H Lurie Comprehensive Cancer Center of Northwestern University, USA
Am J Clin Oncol 35:399-405. 2012..This expert panel was convened to reach consensus on the selection of appropriate therapies based on patient and disease characteristics at presentation...
International brachytherapy practice patterns: a survey of the Gynecologic Cancer Intergroup (GCIG)Akila N Viswanathan
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 82:250-5. 2012....
Combined modality therapy in the treatment of gynecologic malignanciesMark A Engleman
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
Semin Oncol 30:80-94. 2003..Combined modality therapy has played an increasingly important role in the treatment of gynecologic malignancies and its role continues to evolve and expand...
Radiation-induced skeletal injuryMark A Engleman
Radiation Oncology, The Robert H. Lurie Comprehensive Cancer Center of Northwestern University Medical School, Chicago, IL, USA
Cancer Treat Res 128:155-69. 2006
Radiotherapy for rejection of renal transplant allografts refractory to medical immunosuppressionAndrew O Wahl
Department of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, USA
Am J Clin Oncol 29:551-4. 2006..02). CONCLUSION: In renal allograft transplant recipients who experienced acute rejection episodes refractory to modern chemical immunosuppression, LGI was well tolerated and remains a viable salvage treatment option...
Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlasHiram A Gay
Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110 6311, USA
Int J Radiat Oncol Biol Phys 83:e353-62. 2012..To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials...
Adenocarcinoma arising in rectal duplication cyst: case report and review of the literatureAnand T Shivnani
Division of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA
Am Surg 70:1007-9. 2004....
Radiation toxicity: a practical guide. IntroductionWilliam Small
Division of Radiation Oncology, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Medical School, Chicago, IL, USA
Cancer Treat Res 128:3-5. 2006
The use of stereotactic body radiation therapy in gastrointestinal malignancies in locally advanced and metastatic settingsPolina Khrizman
Hematology Oncology, Northwestern University, Chicago, IL, USA
Clin Colorectal Cancer 9:136-43. 2010..It will review available data and will discuss future directions in the GI field...
Survival outcomes in resected extrahepatic cholangiocarcinoma: effect of adjuvant radiotherapy in a surveillance, epidemiology, and end results analysisTamara Z Vern-Gross
Department of Radiation Oncology, Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
Int J Radiat Oncol Biol Phys 81:189-98. 2011..We analyzed survival outcomes of patients with resected extrahepatic cholangiocarcinoma and examined the effect of adjuvant RT...
Dosimetry and toxicity outcomes in postoperative high-dose-rate intracavitary brachytherapy for endometrial carcinomaEric D Donnelly
Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
J Contemp Brachytherapy 4:135-40. 2012..Our aim was to evaluate the utility of bladder and rectal dosimetry for patients receiving HDR-VB for postoperative treatment of endometrial carcinoma...
Clitoral therapy device for treatment of sexual dysfunction in irradiated cervical cancer patientsMaryann Schroder
Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637, USA
Int J Radiat Oncol Biol Phys 61:1078-86. 2005..The purpose of this pilot study was to evaluate the efficacy of the clitoral therapy device (Eros Therapy) in alleviating sexual dysfunction in irradiated cervical cancer patients...
Radiation-induced lung injuryLawrence B Marks
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Semin Radiat Oncol 13:333-45. 2003..Sophisticated planning/delivery methods, such as intensity modulation, plus radioprotectors such as amifostine, hold promise to reduce the incidence of RT-induced lung injury...
Repair of massive ventral hernias with the separation of parts technique: reversal of the 'lost domain'Ivan Hadad
Department of Surgery, Division of Plastic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Am Surg 75:301-6. 2009..The separation of parts technique is able to close large ventral hernias without a high incidence of pulmonary complications as a result of its ability to expand the abdominal domain without a change in diaphragmatic height...
Chemotherapy for pancreatic cancerChristopher H Crane
N Engl J Med 350:2713-5; author reply 2713-5. 2004
Neoadjuvant induction chemotherapy followed by chemoradiation: a phase I trial of gemcitabine, cisplatin, and 5-fluorouracil for advanced pancreatic/gastrointestinal malignanciesCharles A Staley
Division of Surgical Oncology, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USA
Surg Oncol Clin N Am 13:697-709, x. 2004..Here they report the results of a phase I/II trial of gemcitabine, cisplatin, and 5-FU for patients with advanced gastrointestinal malignancies...
The role of amifostine in the treatment of carcinoma of the uterine cervix: an update of RTOG-0116 and review of future directionsJennifer F De Los Santos
The University of Alabama at Birmingham, AL 35243, USA
Semin Oncol 31:37-41. 2004....
MDCT of thoraco-abdominal trauma: an evaluation of the success and limitations of primary interpretation using multiplanar reformatted images vs axial imagesAshok Jayashankar
Division of Abdominal Imaging, Department of Radiology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
Emerg Radiol 15:29-34. 2008..However, the use of MPR images alone still resulted in an unacceptably high number of missed soft tissue and even skeletal findings. A combined approach where both data sets are simultaneously available is therefore preferred...
Cervical cancerBenjamin E Greer
J Natl Compr Canc Netw 6:14-36. 2008
To plan or not to plan? That is the questionWilliam Small
Brachytherapy 5:216-7. 2006
Uterine cancersBenjamin E Greer
Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance, Seattle, WA, USA
J Natl Compr Canc Netw 4:438-62. 2006
