Sanjiv J Shah

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Evolving approaches to the management of heart failure with preserved ejection fraction in patients with coronary artery disease
    Sanjiv J Shah
    Bluhm Cardiovascular Institute, Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Suite 600, Chicago, IL, 60611, USA
    Curr Treat Options Cardiovasc Med 12:58-75. 2010
  2. pmc Baseline characteristics of patients in the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Circ Heart Fail 6:184-92. 2013
  3. doi request reprint Pulmonary hypertension
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    JAMA 308:1366-74. 2012
  4. pmc Phase II trials in heart failure: the role of cardiovascular imaging
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am Heart J 162:3-15.e3. 2011
  5. doi request reprint Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Trial in P
    Sanjiv J Shah
    Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am Heart J 157:1035-41. 2009
  6. ncbi request reprint Genetics of systemic sclerosis-associated pulmonary arterial hypertension: recent progress and current concepts
    Sanjiv J Shah
    Center for Heart Failure, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, 676 N St Clair Street, Suite 600, Chicago, IL 60611, USA
    Curr Rheumatol Rep 11:89-96. 2009
  7. doi request reprint Real-time three-dimensional transesophageal echocardiography of the left atrial appendage: initial experience in the clinical setting
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Am Soc Echocardiogr 21:1362-8. 2008
  8. pmc Association of the fourth heart sound with increased left ventricular end-diastolic stiffness
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    J Card Fail 14:431-6. 2008
  9. ncbi request reprint Physiology of the third heart sound: novel insights from tissue Doppler imaging
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California, USA
    J Am Soc Echocardiogr 21:394-400. 2008
  10. pmc Association of low-grade albuminuria with adverse cardiac mechanics: findings from the hypertension genetic epidemiology network (HyperGEN) study
    Daniel H Katz
    Division of Cardiology, Department of Medicine D H K, S S, F G A, E E M, L B, S J S and Department of Preventive Medicine K Y A K, J P, Northwestern University Feinberg School of Medicine, Chicago, IL Departments of Epidemiology and Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL J S, M R I, D K A Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN J H E the Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN S T T and the Section of Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, NC B I F
    Circulation 129:42-50. 2014

Detail Information

Publications45

  1. ncbi request reprint Evolving approaches to the management of heart failure with preserved ejection fraction in patients with coronary artery disease
    Sanjiv J Shah
    Bluhm Cardiovascular Institute, Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Suite 600, Chicago, IL, 60611, USA
    Curr Treat Options Cardiovasc Med 12:58-75. 2010
    ..The combination of systematic evaluation and management of CAD in HFpEF, along with promising future therapies for HFpEF-CAD, may lead to improved outcomes for this challenging clinical syndrome...
  2. pmc Baseline characteristics of patients in the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Circ Heart Fail 6:184-92. 2013
    ..We sought to describe the baseline clinical characteristics of subjects enrolled in TOPCAT relative to other contemporary observational studies and randomized clinical trials of HFpEF...
  3. doi request reprint Pulmonary hypertension
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    JAMA 308:1366-74. 2012
    ....
  4. pmc Phase II trials in heart failure: the role of cardiovascular imaging
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am Heart J 162:3-15.e3. 2011
    ....
  5. doi request reprint Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Trial in P
    Sanjiv J Shah
    Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am Heart J 157:1035-41. 2009
    ....
  6. ncbi request reprint Genetics of systemic sclerosis-associated pulmonary arterial hypertension: recent progress and current concepts
    Sanjiv J Shah
    Center for Heart Failure, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, 676 N St Clair Street, Suite 600, Chicago, IL 60611, USA
    Curr Rheumatol Rep 11:89-96. 2009
    ....
  7. doi request reprint Real-time three-dimensional transesophageal echocardiography of the left atrial appendage: initial experience in the clinical setting
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Am Soc Echocardiogr 21:1362-8. 2008
    ..The aim of this study was to determine the feasibility and accuracy of a new real-time 3-dimensional (RT3D) matrix-array transesophageal echocardiographic probe for the determination of left atrial appendage (LAA) geometry...
  8. pmc Association of the fourth heart sound with increased left ventricular end-diastolic stiffness
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    J Card Fail 14:431-6. 2008
    ..We hypothesized that the S(4) is associated with an upward- and leftward-shifted EDPVR, indicative of elevated end-diastolic stiffness...
  9. ncbi request reprint Physiology of the third heart sound: novel insights from tissue Doppler imaging
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California, USA
    J Am Soc Echocardiogr 21:394-400. 2008
    ..We sought to determine whether the ratio of early mitral inflow velocity to diastolic velocity of the mitral annulus (E/E') could confirm the proposed mechanism of the S(3)...
  10. pmc Association of low-grade albuminuria with adverse cardiac mechanics: findings from the hypertension genetic epidemiology network (HyperGEN) study
    Daniel H Katz
    Division of Cardiology, Department of Medicine D H K, S S, F G A, E E M, L B, S J S and Department of Preventive Medicine K Y A K, J P, Northwestern University Feinberg School of Medicine, Chicago, IL Departments of Epidemiology and Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL J S, M R I, D K A Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN J H E the Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN S T T and the Section of Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, NC B I F
    Circulation 129:42-50. 2014
    ..The reasons for this association are unclear but may be attributable to the relationship between endothelial dysfunction and intrinsic myocardial dysfunction...
  11. doi request reprint Ultrastructural and cellular basis for the development of abnormal myocardial mechanics during the transition from hypertension to heart failure
    Sanjiv J Shah
    Department of Medicine Cardiology and the Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    Am J Physiol Heart Circ Physiol 306:H88-100. 2014
    ..These changes occur before the development of significant cardiac fibrosis and precede the development of overt cardiac dysfunction and HF. ..
  12. doi request reprint Cardiac involvement and treatment-related mortality after non-myeloablative haemopoietic stem-cell transplantation with unselected autologous peripheral blood for patients with systemic sclerosis: a retrospective analysis
    Richard K Burt
    Division of Immunotherapy, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Lancet 381:1116-24. 2013
    ..We aimed to assess efficacy of HSCT and use of rigorous cardiac screening in this group...
  13. pmc Prevalence, prognosis, and factors associated with left ventricular diastolic dysfunction in systemic sclerosis
    Monique Hinchcliff
    Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Clin Exp Rheumatol 30:S30-7. 2012
    ..To determine the frequency, associated clinical factors, and prognostic significance of left ventricular (LV) diastolic dysfunction in systemic sclerosis (SSc)...
  14. pmc Prognostic value of left ventricular end-systolic volume index as a predictor of heart failure hospitalization in stable coronary artery disease: data from the Heart and Soul Study
    David D McManus
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California 94143, USA
    J Am Soc Echocardiogr 22:190-7. 2009
    ..The prognostic value of ESVI and its merit relative to other markers of LV remodeling in patients with coronary heart disease are unknown...
  15. doi request reprint Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Circ Heart Fail 2:278-86. 2009
    ..The ability of the Naughton-Balke exercise treadmill test, an objective indicator of exercise capacity, to predict abnormal hemodynamics and mortality in pulmonary hypertension is unknown...
  16. pmc Prevalence, clinical phenotype, and outcomes associated with normal B-type natriuretic peptide levels in heart failure with preserved ejection fraction
    Venkatesh Y Anjan
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Cardiol 110:870-6. 2012
    ....
  17. doi request reprint Risk assessment in pulmonary hypertension associated with heart failure and preserved ejection fraction
    Richa Agarwal
    Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    J Heart Lung Transplant 31:467-77. 2012
    ..Pulmonary hypertension (PH) is common in patients with left heart failure (HF), especially those with HF and preserved ejection fraction (HFpEF). However, there is limited data on risk stratification in these patients...
  18. doi request reprint Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension
    Sonal Chandra
    Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois
    J Heart Lung Transplant 29:181-7. 2010
    ..Little is known of its prognostic utility in World Health Organization (WHO) Group I PAH...
  19. pmc Prevalence, clinical characteristics, and outcomes associated with eccentric versus concentric left ventricular hypertrophy in heart failure with preserved ejection fraction
    Daniel H Katz
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    Am J Cardiol 112:1158-64. 2013
    ..In conclusion, the presence of EH denotes a distinct subset of HFpEF that is pathophysiologically similar to HF with reduced EF (HFrEF) and may benefit from HFrEF therapy. ..
  20. pmc Association of serum triiodothyronine with B-type natriuretic peptide and severe left ventricular diastolic dysfunction in heart failure with preserved ejection fraction
    Senthil Selvaraj
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 110:234-9. 2012
    ..1 to -2.5 ng/dl, p = 0.022). In conclusion, T(3) is inversely associated with markers of HFpEF severity (BNP and DD). Whether reduced T(3) contributes to or is a consequence of increased severity of HFpEF remains to be determined...
  21. pmc Diastolic electromechanical coupling: association of the ECG T-peak to T-end interval with echocardiographic markers of diastolic dysfunction
    Andrew Sauer
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Circ Arrhythm Electrophysiol 5:537-43. 2012
    ..We hypothesized that the ECG T-peak to T-end (TpTe) interval, representing transmural dispersion of repolarization, is associated with echocardiographic markers of diastolic dysfunction (DD)...
  22. pmc Relation of short-term heart rate variability to incident heart failure (from the Multi-Ethnic Study of Atherosclerosis)
    Sidharth A Shah
    Division of Cardiology, Department of Medicine, Wake Forest University, Winston Salem, NC, USA
    Am J Cardiol 112:533-40. 2013
    ..These population-based findings implicate autonomic dysfunction in the pathogenesis of HF, and decreased short-term heart rate variability might be a novel form of stage B (asymptomatic) HF...
  23. pmc Usefulness of electrocardiographic QT interval to predict left ventricular diastolic dysfunction
    Jane E Wilcox
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 108:1760-6. 2011
    ..004), confirming our phase 1 study findings. In conclusion, QTc prolongation was the electrocardiographic marker most predictive of DD and was independently associated with DD...
  24. pmc Association of African American race with elevated pulmonary artery diastolic pressure: data from the Heart and Soul Study
    Kiran K Khush
    Division of Cardiology, University of California, San Francisco, California 94143 0124, USA
    J Am Soc Echocardiogr 20:1307-13. 2007
    ..We hypothesized that African American race is associated with an elevated EDPR gradient that may partially predispose African Americans to heart failure...
  25. doi request reprint Usefulness of red cell distribution width as a prognostic marker in pulmonary hypertension
    Chetan V Hampole
    Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Am J Cardiol 104:868-72. 2009
    ..39 for NT-pro-BNP). Adding NT-pro-BNP to RDW did not improve the prediction of mortality. In conclusion, RDW is independently associated with death in patients with PH and performs better as a prognostic indicator than NT-pro-BNP...
  26. doi request reprint Selective serotonin reuptake inhibitors and the incidence and outcome of pulmonary hypertension
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60637, USA
    Chest 136:694-700. 2009
    ..We sought to determine whether SSRIs are associated with a decreased incidence of PH in at-risk patients and whether SSRIs are associated with decreased mortality in patients with established PH...
  27. pmc Association of the frontal QRS-T angle with adverse cardiac remodeling, impaired left and right ventricular function, and worse outcomes in heart failure with preserved ejection fraction
    Senthil Selvaraj
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    J Am Soc Echocardiogr 27:74-82.e2. 2014
    ..The aim of this study was to test the hypothesis that increased frontal QRS-T angle is associated with worse cardiac function and remodeling and adverse outcomes in HFpEF...
  28. doi request reprint Noninvasive estimation of left ventricular compliance using three-dimensional echocardiography
    Etienne Gayat
    University of Chicago Medical Center, Chicago, Illinois 60637, USA
    J Am Soc Echocardiogr 25:661-6. 2012
    ..The aim of this study was to test the feasibility of noninvasive estimation of the EDPVR as a tool to evaluate LV compliance using three-dimensional echocardiography...
  29. doi request reprint Clinical characteristics of pulmonary hypertension in patients with heart failure and preserved ejection fraction
    Thenappan Thenappan
    Section of Cardiology, Department of Medicine, University of Chicago, IL, USA
    Circ Heart Fail 4:257-65. 2011
    ..The distinction between PH-HFpEF and pulmonary arterial hypertension (PAH) is important because therapies indicated for PAH can be detrimental in HFpEF. The characteristic features of PH-HFpEF are understudied...
  30. doi request reprint Acute effects of intravenous nesiritide on cardiac contractility in heart failure
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Card Fail 16:720-7. 2010
    ..We sought to determine whether nesiritide decreases contractility in heart failure patients...
  31. doi request reprint Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill 60637, USA
    Circulation 117:2475-83. 2008
    ..Renal dysfunction predicts mortality in patients with cardiovascular disease. How renal dysfunction relates to hemodynamics and mortality in pulmonary arterial hypertension (PAH) remains unclear...
  32. pmc Systemic sclerosis and the heart: current diagnosis and management
    Chintan S Desai
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Curr Opin Rheumatol 23:545-54. 2011
    ..It is therefore vitally important to understand the epidemiology, screening, diagnosis, and treatment of the cardiac manifestations of SSc...
  33. doi request reprint Heart failure with preserved ejection fraction: treat now by treating comorbidities
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    JAMA 300:431-3. 2008
  34. doi request reprint Inaccuracy of Doppler echocardiographic estimates of pulmonary artery pressures in patients with pulmonary hypertension: implications for clinical practice
    Jonathan D Rich
    Pritzker School of Medicine Section of Cardiology, Chicago, IL, USA
    Chest 139:988-93. 2011
    ..We sought to determine the accuracy of PASP measurements using DE compared with right-sided heart catheterization (RHC) in patients with pulmonary hypertension (PH)...
  35. doi request reprint Cardiovascular risk assessment of the liver transplant candidate
    Zankhana Raval
    Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Am Coll Cardiol 58:223-31. 2011
    ..The following provides a review of the cardiovascular challenges in LT candidates, as well as evidence-based recommendations for their evaluation and management...
  36. pmc Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis
    Monique Hinchcliff
    Department of Internal Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Invest Dermatol 133:1979-89. 2013
    ..Baseline gene expression in skin, including intrinsic subset assignment, may identify SSc patients whose MRSS will improve during MMF treatment, suggesting that gene expression in skin may allow targeted treatment in SSc...
  37. pmc Acute myocardial infarction in patients with versus without aortic valve sclerosis and effect of statin therapy (from the Heart and Soul Study)
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Am J Cardiol 99:1128-33. 2007
    ..4-fold increased rate of subsequent MI. Statins may attenuate the increased risk of future MI in patients with aortic sclerosis...
  38. doi request reprint Normalization of ejection fraction and resolution of symptoms in chronic severe heart failure is possible with modern medical therapy: clinical observations in 11 patients
    Matthew E Harinstein
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Ther 15:206-13. 2008
    ..Given the unique metabolic needs of the failing heart, the role of micronutrients in combination with standard therapy warrants further investigation...
  39. doi request reprint MDCT bolus tracking data as an adjunct for predicting the diagnosis of pulmonary hypertension and concomitant right-heart failure
    Amir H Davarpanah
    Department of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    AJR Am J Roentgenol 197:1064-72. 2011
    ....
  40. doi request reprint Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial
    Richard K Burt
    Division of Immunotherapy, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Lancet 378:498-506. 2011
    ..We aimed to assess safety and efficacy of autologous non-myeloablative HSCT in a phase 2 trial compared with the standard of care, cyclophosphamide...
  41. doi request reprint Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat
    Gary L Aistrup
    Department of Medicine Cardiologyand the Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois and
    Am J Physiol Heart Circ Physiol 305:H1068-79. 2013
    ..Early, chronic inhibition of this current slows both hypertrophy and development of ultrastructural and physiological defects associated with the progression to HF...
  42. doi request reprint Intensive lipid-lowering with atorvastatin for secondary prevention in patients after coronary artery bypass surgery
    Sanjiv J Shah
    Division of Cardiology, San Francisco General Hospital, University of California, San Francisco, California 94110, USA
    J Am Coll Cardiol 51:1938-43. 2008
    ....
  43. ncbi request reprint Nesiritide: a reappraisal of efficacy and safety
    Sanjiv J Shah
    University of California, Division of Cardiology, Department of Medicine, San Francisco, USA
    Expert Opin Pharmacother 8:361-9. 2007
    ..A large outcomes trial in patients with ADHF would help clarify the role of nesiritide...
  44. ncbi request reprint High-sensitivity C-reactive protein and parameters of left ventricular dysfunction
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, University of California, San Francisco, 94143, USA
    J Card Fail 12:61-5. 2006
    ..Elevated levels of high-sensitivity C-reactive protein (CRP), an inflammatory marker, have been associated with heart failure. However, it is not known which parameters of left ventricular dysfunction correlate with elevated levels of CRP...
  45. ncbi request reprint Has acetylcysteine use changed the incidence of contrast nephropathy in hospitalized patients? A before-after study
    Sanjiv J Shah
    Department of Medicine, University of California, San Francisco, California 94143 0124, USA
    Am J Med 117:948-52. 2004