Bettina Schreiner

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint T-cell response dynamics in animal models of multiple sclerosis: implications for immunotherapies
    Bettina Schreiner
    Northwestern University Medical School, Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, 303 E Chicago Avenue Chicago, IL 60611, USA
    Expert Rev Clin Immunol 3:57-72. 2007
  2. ncbi request reprint Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis
    Stephen D Miller
    Department of Microbiology, Northwestern University Medical School, Chicago, IL 60611, USA
    Ann N Y Acad Sci 1103:179-91. 2007
  3. pmc PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE
    Bettina Schreiner
    Department of Microbiology Immunology and Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Eur J Immunol 38:2706-17. 2008
  4. ncbi request reprint CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE
    Samantha L Bailey
    Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Nat Immunol 8:172-80. 2007

Collaborators

Detail Information

Publications4

  1. ncbi request reprint T-cell response dynamics in animal models of multiple sclerosis: implications for immunotherapies
    Bettina Schreiner
    Northwestern University Medical School, Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, 303 E Chicago Avenue Chicago, IL 60611, USA
    Expert Rev Clin Immunol 3:57-72. 2007
    ..Here, we review the current knowledge of the mechanisms of induction and progression of EAE and MS and the immunotherapies that have resulted from studies of the EAE model...
  2. ncbi request reprint Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis
    Stephen D Miller
    Department of Microbiology, Northwestern University Medical School, Chicago, IL 60611, USA
    Ann N Y Acad Sci 1103:179-91. 2007
    ..In contrast, CNS-resident CD11b(+)CD11c(-)CD45(low) microglia purified from the inflamed CNS were found to be largely incapable of activating either naïve or effector T cells...
  3. pmc PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE
    Bettina Schreiner
    Department of Microbiology Immunology and Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Eur J Immunol 38:2706-17. 2008
    ..In contrast, blockade of B7-DC has less pronounced regulatory effects. Overall, the results demonstrate that B7-H1 expressed by CNS myeloid APC negatively regulates T-cell activation during acute relapsing EAE...
  4. ncbi request reprint CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE
    Samantha L Bailey
    Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Nat Immunol 8:172-80. 2007
    ..Our findings indicate a critical function for CNS mDCs in driving relapses in relapsing EAE...