Marc H Scheetz

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Lack of effect of fluoroquinolone resistance on mortality in subjects with Pseudomonas aeruginosa bacteraemia
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, 251 East Huron Street, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    J Infect 52:105-10. 2006
  2. pmc Increasing incidence of linezolid-intermediate or -resistant, vancomycin-resistant Enterococcus faecium strains parallels increasing linezolid consumption
    Marc H Scheetz
    Midwestern University Chicago College of Pharmacy, Infectious Diseases Pharmacist, Northwestern Memorial Hospital, 251 E Huron St, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    Antimicrob Agents Chemother 52:2256-9. 2008
  3. pmc Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes
    Milena M McLaughlin
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, 555 31st Street, Downers Grove, IL 60515, USA
    BMC Infect Dis 14:31. 2014
  4. doi request reprint Cost-effectiveness analysis of an antimicrobial stewardship team on bloodstream infections: a probabilistic analysis
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA
    J Antimicrob Chemother 63:816-25. 2009
  5. doi request reprint Pharmacokinetic assessment of peramivir in a hospitalized adult undergoing continuous venovenous hemofiltration
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA
    Ann Pharmacother 45:e64. 2011
  6. pmc In vitro activities of various antimicrobials alone and in combination with tigecycline against carbapenem-intermediate or -resistant Acinetobacter baumannii
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    Antimicrob Agents Chemother 51:1621-6. 2007
  7. ncbi request reprint Peritoneal fluid penetration of tigecycline
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611 2908, USA
    Ann Pharmacother 40:2064-7. 2006
  8. doi request reprint Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois 60515, USA
    Pharmacotherapy 31:469-79. 2011
  9. ncbi request reprint The clinical impact of linezolid susceptibility reporting in patients with vancomycin-resistant enterococci
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Diagn Microbiol Infect Dis 56:407-13. 2006
  10. ncbi request reprint Applying antimicrobial pharmacodynamics to resistant gram-negative pathogens
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Am J Health Syst Pharm 63:1346-60. 2006

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Lack of effect of fluoroquinolone resistance on mortality in subjects with Pseudomonas aeruginosa bacteraemia
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, 251 East Huron Street, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    J Infect 52:105-10. 2006
    ..Despite the well-documented increase in fluoroquinolone resistance to Pseudomonas aeruginosa, the effect on pathogenicity is unknown. This paper will explore the clinical effect...
  2. pmc Increasing incidence of linezolid-intermediate or -resistant, vancomycin-resistant Enterococcus faecium strains parallels increasing linezolid consumption
    Marc H Scheetz
    Midwestern University Chicago College of Pharmacy, Infectious Diseases Pharmacist, Northwestern Memorial Hospital, 251 E Huron St, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    Antimicrob Agents Chemother 52:2256-9. 2008
    ..A relationship was found (r(2) = 0.73, P = 0.03) and predicts increasing resistance with current trends of linezolid use...
  3. pmc Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes
    Milena M McLaughlin
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, 555 31st Street, Downers Grove, IL 60515, USA
    BMC Infect Dis 14:31. 2014
    ..This pilot study sought to evaluate KPC virulence by combining clinical and Galleria mellonella models in patients with K. pneumoniae blood stream infections (BSIs)...
  4. doi request reprint Cost-effectiveness analysis of an antimicrobial stewardship team on bloodstream infections: a probabilistic analysis
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA
    J Antimicrob Chemother 63:816-25. 2009
    ..We sought to determine the cost-effectiveness of Antimicrobial Stewardship Teams (ASTs) on the reduction of morbidity and mortality associated with nosocomial bacteraemia...
  5. doi request reprint Pharmacokinetic assessment of peramivir in a hospitalized adult undergoing continuous venovenous hemofiltration
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA
    Ann Pharmacother 45:e64. 2011
    ..To report a sieving coefficient for peramivir in a patient receiving continuous venovenous hemofiltration (CVVH)...
  6. pmc In vitro activities of various antimicrobials alone and in combination with tigecycline against carbapenem-intermediate or -resistant Acinetobacter baumannii
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Feinberg Pavilion LC 700, Chicago, IL 60611, USA
    Antimicrob Agents Chemother 51:1621-6. 2007
    ..Future studies should evaluate these findings in vivo...
  7. ncbi request reprint Peritoneal fluid penetration of tigecycline
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611 2908, USA
    Ann Pharmacother 40:2064-7. 2006
    ..To describe the peritoneal fluid penetration of tigecycline...
  8. doi request reprint Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois 60515, USA
    Pharmacotherapy 31:469-79. 2011
    ....
  9. ncbi request reprint The clinical impact of linezolid susceptibility reporting in patients with vancomycin-resistant enterococci
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Diagn Microbiol Infect Dis 56:407-13. 2006
    ..006). Therefore, inaccurate detection and reporting of LIRVRE by disk diffusion and Etest is associated with increased patient morbidity and resource use...
  10. ncbi request reprint Applying antimicrobial pharmacodynamics to resistant gram-negative pathogens
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Am J Health Syst Pharm 63:1346-60. 2006
    ..Guided antibiotic adjustment for the treatment of multidrug-resistant, gram-negative pathogens is explored...
  11. ncbi request reprint Potential impact of vancomycin pulmonary distribution on treatment outcomes in patients with methicillin-resistant Staphylococcus aureus pneumonia
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Pharmacotherapy 26:539-50. 2006
    ..The possibility of increased serum vancomycin concentrations as a method to optimize current treatment outcomes is also explored...
  12. doi request reprint Differences in clinical outcomes in patients with vancomycin-resistant enterococci according to linezolid susceptibility
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA
    Pharmacotherapy 30:1221-8. 2010
    ....
  13. pmc Virulence of vancomycin-resistant Enterococcus faecium according to linezolid resistance and clinical outbreak status
    Milena McLaughlin
    Midwestern University, Downers Grove, Illinois, USA
    Antimicrob Agents Chemother 57:3923-7. 2013
    ..78). These results suggest that patients infected with LRVRE or outbreak strains of VREF are at no greater risk of poor outcomes mediated by organism virulence than those infected with LSVRE or non-outbreak strains. ..
  14. pmc Impact of carbapenem resistance and receipt of active antimicrobial therapy on clinical outcomes of Acinetobacter baumannii bloodstream infections
    John S Esterly
    Department of Pharmacy Practice, Chicago State University College of Pharmacy, Chicago, Illinois, USA
    Antimicrob Agents Chemother 55:4844-9. 2011
    ..Inactive therapy was more important than carbapenem susceptibility with respect to outcomes, was a strong predictor of death, and is potentially modifiable...
  15. doi request reprint Characterization of ciprofloxacin resistant Escherichia coli isolates among men undergoing evaluation for transrectal ultrasound guided prostate biopsy
    Chao Qi
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Clinical Microbiology Laboratory, Northwestern Memorial Hospital, Chicago, Illinois Electronic address
    J Urol 190:2026-32. 2013
    ....
  16. pmc Comparison of testing methods for detection of decreased linezolid susceptibility due to G2576T mutation of the 23S rRNA gene in Enterococcus faecium and Enterococcus faecalis
    Chao Qi
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Clin Microbiol 44:1098-100. 2006
    ..Agar and broth dilution methods were in concordance with PCR detection of the mutation, and disk diffusion was somewhat less sensitive but equally specific...
  17. pmc Evaluation of clinical outcomes in patients with bloodstream infections due to Gram-negative bacteria according to carbapenem MIC stratification
    John S Esterly
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA
    Antimicrob Agents Chemother 56:4885-90. 2012
    ..We recommend additional clinical studies to better understand the susceptibility breakpoint for carbapenems...
  18. pmc Impact of inactive empiric antimicrobial therapy on inpatient mortality and length of stay
    Kimberly K Scarsi
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Antimicrob Agents Chemother 50:3355-60. 2006
    ..Inactive antimicrobial therapy in the first 24 h did not significantly impact average outcomes for GNBI among hospitalized patients but may have caused harm to specific individuals...
  19. doi request reprint Predictability of doripenem susceptibility in Acinetobacter baumannii isolates based on other carbapenem susceptibilities and bla OXA gene status
    John S Esterly
    Department of Pharmacy Practice, Midwestern University, Chicago College of Pharmacy, Downers Grove, Illinois 60515, USA
    Pharmacotherapy 30:354-60. 2010
    ..To better define the utility of surrogate markers for doripenem susceptibility relative to gold standard microbiology tests...
  20. pmc Characterization of genetic diversity of carbapenem-resistant Acinetobacter baumannii clinical strains collected from 2004 to 2007
    Chao Qi
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Clin Microbiol 46:1106-9. 2008
    ..Analysis of carbapenemases by PCR revealed that imipenem resistance but not meropenem resistance was associated with the presence of bla(OXA-23) and bla(OXA-40) genes...
  21. pmc Effect of differences in MIC values on clinical outcomes in patients with bloodstream infections caused by gram-negative organisms treated with levofloxacin
    Robyn Defife
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Antimicrob Agents Chemother 53:1074-9. 2009
    ..In vitro susceptibility classifications of fluoroquinolones for the treatment of bloodstream infections caused by gram-negative organisms require further study...
  22. pmc Evaluation of a potential clinical interaction between ceftriaxone and calcium
    Emily Steadman
    Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois 60515, USA
    Antimicrob Agents Chemother 54:1534-40. 2010
    ....
  23. doi request reprint Temporal changes in pulsed-field gel electrophoresis banding in vancomycin-resistant Enterococcus faecium and implications for outbreak investigations
    Milena McLaughlin
    Department of Pharmacy Practice, Chicago College of Pharmacy at Midwestern University, Downers Grove, IL 60515, USA
    Am J Infect Control 41:349-53. 2013
    ..To determine the amount of time between which isolates could be considered genetically similar by pulsed-field gel electrophoresis, isolate change over time within single patients was studied...
  24. ncbi request reprint Prospective approach to managing antimicrobial drug shortages
    Milena M Griffith
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515, USA
    Infect Control Hosp Epidemiol 33:745-52. 2012
    ....
  25. pmc Morbidity associated with Pseudomonas aeruginosa bloodstream infections
    Marc H Scheetz
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515, USA
    Diagn Microbiol Infect Dis 64:311-9. 2009
    ..Because neither of these factors are modifiable, efforts to minimize the negative impact of PABSI should focus on appropriate prevention and infection control efforts...
  26. doi request reprint Characterization of Acinetobacter baumannii genotypes recovered from patients with repeated colonization or infection
    Chao Qi
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Diagn Microbiol Infect Dis 65:1-6. 2009
    ..2 times more likely to have closely related isolates obtained for all subsequent cultures than patients with initial carbapenem-intermediate or carbapenem-susceptible isolates...
  27. pmc Correlations of antibiotic use and carbapenem resistance in enterobacteriaceae
    Milena McLaughlin
    Midwestern University, Downers Grove, Illinois, USA
    Antimicrob Agents Chemother 57:5131-3. 2013
    ..When conservative corrections were applied for multiple comparisons, carbapenem class use and piperacillin-tazobactam use retained significant positive and negative relationships with the incidence of CIRE, respectively. ..
  28. doi request reprint Impact of the FDA warning of potential ceftriaxone and calcium interactions on drug use policy in clinical practice
    John S Esterly
    Department of Pharmacy Practice, Chicago State University College of Pharmacy, Chicago, IL, USA
    Int J Clin Pharm 33:537-42. 2011
    ..We sought to quantify the impact of the warning on healthcare institutions...
  29. doi request reprint Comparison of outcomes from daptomycin or linezolid treatment for vancomycin-resistant enterococcal bloodstream infection: A retrospective, multicenter, cohort study
    Christopher W Crank
    Rush University Medical Center, Chicago, Illinois, USA
    Clin Ther 32:1713-9. 2010
    ..The optimal treatment for bloodstream infections (BSIs) with vancomycin-resistant enterococci (VRE) is unknown...
  30. pmc Evaluation of hepatotoxicity with off-label oral-treatment doses of voriconazole for invasive fungal infections
    Elizabeth Gorski
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA
    Antimicrob Agents Chemother 55:184-9. 2011
    ..No difference existed in liver abnormalities for high-dose voriconazole; however, higher mg/kg doses and a longer duration of therapy may be associated with hepatotoxicity...
  31. doi request reprint Cerebral spinal fluid penetration of tigecycline in a patient with Acinetobacter baumannii cerebritis
    Leslie Ray
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL Center, Tampa, FL, USA
    Ann Pharmacother 44:582-6. 2010
    ..To describe cerebral spinal fluid (CSF) penetration of tigecycline...
  32. doi request reprint Empiric antibiotic selection for infectious emergencies: bacterial pneumonia, meningitis and sepsis
    E Paul O'Donnell
    Northwestern Memorial Hospital, Department of Pharmacy, Chicago, Illinois 60611, USA
    Drugs Today (Barc) 45:379-93. 2009
    ..The most common bacterial pathogens and empiric antibiotic recommendations for immunocompetent adults will be discussed. In addition, circumstances that may influence the selection of certain antibiotics are reviewed...
  33. pmc Results from the first decade of research conducted by the Research on Adverse Drug Events and Reports (RADAR) project
    June M McKoy
    The Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Drug Saf 36:335-47. 2013
    ....
  34. pmc Pathogenicity of clinical Acinetobacter baumannii isolates in a Galleria mellonella host model according to bla(OXA-40) gene and epidemiological outbreak status
    John S Esterly
    Chicago State University, Chicago, Illinois, USA
    Antimicrob Agents Chemother 58:1240-2. 2014
    ..Eight isolates of A. baumannii were studied. Nonoutbreak isolates and blaOXA-40-negative isolates more rapidly killed infected G. mellonella (P < 0.01). ..
  35. doi request reprint Physical compatibility of vancomycin and piperacillin sodium-tazobactam at concentrations typically used during prolonged infusions
    Elizabeth Leung
    Department of Pharmacy Practice, Chicago College of Pharmacy, Midwestern University MU, Downers Grove, IL, USA
    Am J Health Syst Pharm 70:1163-6. 2013
    ..The physical compatibility of vancomycin and piperacillin sodium-tazobactam at dosing concentrations commonly administered during prolonged infusions was studied...
  36. doi request reprint The impact of anti-infective drug shortages on hospitals in the United States: trends and causes
    Milena M Griffith
    Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois 60515, USA
    Clin Infect Dis 54:684-91. 2012
    ..Here we describe the scope of recent anti-infective shortages in the United States and explore the reasons for inadequate drug supply...
  37. pmc Serial plasma voriconazole concentrations after allogeneic hematopoietic stem cell transplantation
    Steven M Trifilio
    Hematopoietic Stem Cell Transplant Program, Northwestern Memorial Hospital, Chicago, Illinois, USA
    Antimicrob Agents Chemother 53:1793-6. 2009
    ..This suggests that ongoing therapeutic drug monitoring and dose adjustment may be beneficial in patients requiring prolonged voriconazole therapy...
  38. ncbi request reprint Serum piperacillin/tazobactam pharmacokinetics in a morbidly obese individual
    Diane Newman
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Ann Pharmacother 41:1734-9. 2007
    ..To report pharmacokinetic alterations and optimal dosing of piperacillin/tazobactam in an obese patient...
  39. pmc Hepatotoxicity associated with long- versus short-course HIV-prophylactic nevirapine use: a systematic review and meta-analysis from the Research on Adverse Drug events And Reports (RADAR) project
    June M McKoy
    Department of Medicine, Northwestern University Feinberg School of Medicine, and Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Drug Saf 32:147-58. 2009
    ..We describe the incidence of hepatotoxicity with short- versus long-course nevirapine-containing regimens in these groups...
  40. ncbi request reprint Effects on patient care caused by drug shortages: a survey
    Milena McLaughlin
    Midwestern University Chicago College of Pharmacy, Department of Pharmacy Practice, 555 31st St, Downers Grove, IL, 60515, USA
    J Manag Care Pharm 19:783-8. 2013
    ..Patient harms including adverse events and medication errors may occur. Patients may also file complaints because of drug shortages...
  41. doi request reprint Targeted antimicrobial prophylaxis using rectal swab cultures in men undergoing transrectal ultrasound guided prostate biopsy is associated with reduced incidence of postoperative infectious complications and cost of care
    Aisha K Taylor
    Department of Urology, Northwestern University Feinberg School of Medicine, Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    J Urol 187:1275-9. 2012
    ..We evaluated targeted antimicrobial prophylaxis in men undergoing transrectal ultrasound guided prostate biopsy based on rectal swab culture results...
  42. ncbi request reprint Unacceptably High Error Rates in Vitek 2 Testing of Cefepime Susceptibility in Extended-Spectrum-β-Lactamase-Producing Escherichia coli
    Nathaniel J Rhodes
    Department of Pharmacy Practice, Midwestern University, Chicago College of Pharmacy, Downers Grove, Illinois, USA Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA
    Antimicrob Agents Chemother 58:3757-61. 2014
    ..coli. Clinicians should be wary of making treatment decisions on the basis of Vitek 2 susceptibility results for ESBL-producing E. coli. ..
  43. doi request reprint Posaconazole: an oral triazole with an extended spectrum of activity
    Erik J Rachwalski
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA
    Ann Pharmacother 42:1429-38. 2008
    ..To summarize the published clinical data on posaconazole, critically review the New Drug Application data submitted to the Food and Drug Administration, and provide information critical for evaluation and formulary positioning...
  44. ncbi request reprint Leukopenia complicates cytomegalovirus prevention after renal transplantation with alemtuzumab induction
    Jennifer K Walker
    1 Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Transplantation 83:874-82. 2007
    ..By utilizing a preemptive therapeutic strategy with VGCV targeted only toward patients at risk for developing CMV disease, the rate and extent of leukopenia may be reduced...
  45. ncbi request reprint Systematic review of piperacillin-induced neutropenia
    Marc H Scheetz
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Drug Saf 30:295-306. 2007
    ..Report of neutropenia associated with piperacillin usage prior to 15 days of therapy is a novel finding that requires further evaluation. Current reporting methods poorly characterise patient groups at risk...
  46. pmc Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity
    Farheen Shah-Khan
    Division of Nephrology, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Int J Nephrol 2011:436856. 2011
    ..VAN as the sole etiologic factor for nephrotoxic acute tubular necrosis (ATN) has not been described. Here, we report a case of biopsy-proven ATN resulting from VAN...
  47. ncbi request reprint Effect of on-call infectious-diseases pharmacists on antibiotic expenditures
    Marc H Scheetz
    Am J Health Syst Pharm 62:1967-8. 2005