Alan R Sanders

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi Complexities in psychiatric genetics
    A R Sanders
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, Northwestern University, Illinois 60201, USA
    Int Rev Psychiatry 16:284-93. 2004
  2. ncbi Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia
    A R Sanders
    Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, Center for Psychiatric Genetics, Northwestern University, Evanston, IL 60201, USA
    Mol Psychiatry 10:353-65. 2005
  3. doi No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics
    Alan R Sanders
    Department of Psychiatry and Behavioural Sciences, Evanston Northwestern Healthcare Research Institute, Evanston, IL 60201 3137, USA
    Am J Psychiatry 165:497-506. 2008
  4. pmc DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Evanston, Ill, USA
    Hum Hered 64:97-106. 2007
  5. ncbi Genome-wide association study of multiplex schizophrenia pedigrees
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, Calif, USA
    Am J Psychiatry 169:963-73. 2012
  6. pmc Common variants on chromosome 6p22.1 are associated with schizophrenia
    Jianxin Shi
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94304, USA
    Nature 460:753-7. 2009
  7. doi Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 168:302-16. 2011
  8. doi The Internet-based MGS2 control sample: self report of mental illness
    Alan R Sanders
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, NorthShore University Healthsystem, Evanston, Ill 60201 3137, USA
    Am J Psychiatry 167:854-65. 2010
  9. ncbi Neuregulin 1 (NRG1 ) and schizophrenia: analysis of a US family sample and the evidence in the balance
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, and Northwestern University, 1001 University Place, Evanston, IL 60201, USA
    Psychol Med 35:1599-610. 2005
  10. pmc Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines
    Jubao Duan
    Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute Evanston, Illinois 60201, USA
    Sci Rep 3:1318. 2013

Collaborators

Detail Information

Publications26

  1. ncbi Complexities in psychiatric genetics
    A R Sanders
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, Northwestern University, Illinois 60201, USA
    Int Rev Psychiatry 16:284-93. 2004
    ....
  2. ncbi Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia
    A R Sanders
    Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, Center for Psychiatric Genetics, Northwestern University, Evanston, IL 60201, USA
    Mol Psychiatry 10:353-65. 2005
    ....
  3. doi No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics
    Alan R Sanders
    Department of Psychiatry and Behavioural Sciences, Evanston Northwestern Healthcare Research Institute, Evanston, IL 60201 3137, USA
    Am J Psychiatry 165:497-506. 2008
    ....
  4. pmc DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Evanston, Ill, USA
    Hum Hered 64:97-106. 2007
    ..We have performed an association study with two well-characterized family samples not previously investigated at the DTNBP1 locus...
  5. ncbi Genome-wide association study of multiplex schizophrenia pedigrees
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, Calif, USA
    Am J Psychiatry 169:963-73. 2012
    ..The authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common single-nucleotide polymorphisms (SNPs) and rare copy number variants (CNVs)...
  6. pmc Common variants on chromosome 6p22.1 are associated with schizophrenia
    Jianxin Shi
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94304, USA
    Nature 460:753-7. 2009
    ..These results demonstrate that common schizophrenia susceptibility alleles can be detected. The characterization of these signals will suggest important directions for research on susceptibility mechanisms...
  7. doi Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 168:302-16. 2011
    ....
  8. doi The Internet-based MGS2 control sample: self report of mental illness
    Alan R Sanders
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, NorthShore University Healthsystem, Evanston, Ill 60201 3137, USA
    Am J Psychiatry 167:854-65. 2010
    ..The Molecular Genetics of Schizophrenia (MGS2) project recruited an adult control sample of non-Hispanic European-ancestry (N=3,364) and African American (N=1,301) subjects...
  9. ncbi Neuregulin 1 (NRG1 ) and schizophrenia: analysis of a US family sample and the evidence in the balance
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare Research Institute, and Northwestern University, 1001 University Place, Evanston, IL 60201, USA
    Psychol Med 35:1599-610. 2005
    ..A gene from this region, neuregulin 1 (NRG1 ), known to be involved with glutamatergic function, has been found to be associated in some studied samples...
  10. pmc Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines
    Jubao Duan
    Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute Evanston, Illinois 60201, USA
    Sci Rep 3:1318. 2013
    ..These results suggest widespread interindividual differences in RNA stability related to DNA sequence and composition variation...
  11. pmc Genome-wide linkage and follow-up association study of postpartum mood symptoms
    Pamela Belmonte Mahon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    Am J Psychiatry 166:1229-37. 2009
    ..The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms...
  12. pmc Transcriptome study of differential expression in schizophrenia
    Alan R Sanders
    Department of Psychiatry and Behavioral Sciences, NorthShore University Healthsystem, Evanston, IL 60201, USA
    Hum Mol Genet 22:5001-14. 2013
    ..g. MIR137, the second strongest GWAS finding). Our analysis provides novel candidate genes for further study to assess their potential contribution to schizophrenia. ..
  13. pmc Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Evanston, IL, USA
    Am J Hum Genet 75:624-38. 2004
    ..These data provide strong preliminary evidence that TRAR4 is a candidate gene for schizophrenia; replication is currently being attempted in additional clinical samples...
  14. doi Genetics of schizophrenia: new findings and challenges
    Pablo V Gejman
    Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute, Evanston, Illinois 60201, USA
    Annu Rev Genomics Hum Genet 12:121-44. 2011
    ..A main challenge for the field is the translation of established genetic associations into a better pathophysiological understanding of schizophrenia...
  15. pmc The role of genetics in the etiology of schizophrenia
    Pablo V Gejman
    Department of Psychiatry and Behavioral Sciences and Research Institute, Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute, Evanston, IL 60201, USA
    Psychiatr Clin North Am 33:35-66. 2010
    ....
  16. ncbi [The etiology of schizophrenia]
    Pablo V Gejman
    Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute, Evanston, Illinois, USA
    Medicina (B Aires) 72:227-34. 2012
    ..The current and upcoming resequencing programs - both exomes (all exons) and full genomes - and genome-wide transcriptional analyses will allow a more thorough dissection of the molecular genetics of the disorder...
  17. pmc Genome-wide approaches to schizophrenia
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, 1001 University Place, Evanston, IL 60201, USA
    Brain Res Bull 83:93-102. 2010
    ..Deep resequencing for rare variants and system biology approaches (e.g., integrating DNA sequence and functional data) are expected to further improve our understanding of the genetic architecture of SZ and its underlying biology...
  18. ncbi Polymorphisms in the 5'-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression
    J Duan
    Center for Psychiatric Genetics, Evanston Northwestern Healthcare ENH Research Institute, ENH and Northwestern University, Evanston, IL 60206, USA
    Mol Psychiatry 8:901-10. 2003
    ..Our results indicate that HTR1B is the target of substantial transcriptional genetic regulation by common haplotypes, which are in LD with the HTR1B single-nucleotide polymorphism (SNP) most commonly used in association studies...
  19. pmc Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder
    Pamela Belmonte Mahon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    Am J Med Genet B Neuropsychiatr Genet 156:370-8. 2011
    ..8 years in age at onset. Age at onset and psychotic symptoms in BP may be influenced by many genes of smaller effect sizes or other variants not measured well by SNP arrays, such as rare alleles...
  20. doi Biodemographic and physical correlates of sexual orientation in men
    Gene Schwartz
    Department of Psychology, Northwestern University, Evanston, IL, USA
    Arch Sex Behav 39:93-109. 2010
    ....
  21. pmc Genomewide association for schizophrenia in the CATIE study: results of stage 1
    P F Sullivan
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7264, USA
    Mol Psychiatry 13:570-84. 2008
    ....
  22. pmc Whole-genome association study of bipolar disorder
    P Sklar
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Mol Psychiatry 13:558-69. 2008
    ..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...
  23. pmc Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample
    Brian K Suarez
    Department of Psychiatry and Genetics, Washington University, St Louis, MO, USA
    Am J Hum Genet 78:315-33. 2006
    ..3-p15.2, 5p15.2-q13.3, 10p15.3-p14, 10q25.3-q26.3, and 11p13-q23.3. The highest increase in Z(lr) scores was observed for 5p14.1-q12.1, where the maximum Z(lr) increased from 2.77 initially to 3.80 after fine mapping in the EA families...
  24. ncbi No major schizophrenia locus detected on chromosome 1q in a large multicenter sample
    Douglas F Levinson
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Science 296:739-41. 2002
    ..If schizophrenia susceptibility genes are present on chromosome 1q, their population-wide genetic effects are likely to be small...
  25. ncbi Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor
    Jubao Duan
    Schizophrenia Genetics Research Program, Department of Psychiatry, The University of Chicago, Jules F Knapp Medical Research Center, Chicago, IL 60637, USA
    Hum Mol Genet 12:205-16. 2003
    ....
  26. ncbi DNA variation and psychopharmacology of the human serotonin receptor 1B (HTR1B) gene
    Alan R Sanders
    Schizophrenia Genetics Research Program, Department of Psychiatry, The University of Chicago, Jules F Knapp Research Building, 924 East 57th Street, Room R 004, IL 60637, USA
    Pharmacogenomics 3:745-62. 2002
    ....