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Genomes and GenesSpecies | Anne H RowleySummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Searching for the cause of Kawasaki disease--cytoplasmic inclusion bodies provide new insightAnne H Rowley
Department of Pediatrics, Northwestern University Feinberg School of Medicine, The Center for Kawasaki Disease, The Children s Memorial Hospital, Chicago, Illinois 60611, USA
Nat Rev Microbiol 6:394-401. 2008..Recently, identification of an antigen-driven IgA response that was directed at cytoplasmic inclusion bodies in KD tissues has provided new insights that could unlock the mysteries of KD...
Cloning the arterial IgA antibody response during acute Kawasaki diseaseAnne H Rowley
Department of Pediatrics, The Feinberg School of Medicine, Northwestern University, The Children s Memorial Hospital, Chicago, IL 60611, USA
J Immunol 175:8386-91. 2005....
Cytoplasmic inclusion bodies are detected by synthetic antibody in ciliated bronchial epithelium during acute Kawasaki diseaseAnne H Rowley
Department of Pediatrics, Feinberg School of Medicine, Children s Memorial Hospital, Northwestern University, Chicago, IL 60611, USA
J Infect Dis 192:1757-66. 2005..We have previously reported that oligoclonal immunoglobulin A plasma cells infiltrate acute KD tissues and that synthetic KD antibodies detect a distinctive spheroidal antigen in acute KD ciliated bronchial epithelium...
RNA-containing cytoplasmic inclusion bodies in ciliated bronchial epithelium months to years after acute Kawasaki diseaseAnne H Rowley
Department of Pediatrics, Northwestern University Feinberg School of Medicine, The Center for Kawasaki Disease, The Children s Memorial Hospital, Chicago, Illinois, USA
PLoS ONE 3:e1582. 2008..The prevalence of ICI in late-stage KD fatalities and in older individuals with non-KD illness should be low, unless persistent infection is common...
New developments in the search for the etiologic agent of Kawasaki diseaseAnne H Rowley
Northwestern University Feinberg School of Medicine, The Children s Memorial Hospital, Chicago, Illinois 60601, USA
Curr Opin Pediatr 19:71-4. 2007..The aim of this article is to review recent developments in the search for the etiologic agent of Kawasaki disease...
Detection of antigen in bronchial epithelium and macrophages in acute Kawasaki disease by use of synthetic antibodyAnne H Rowley
Departments of Pediatrics and Microbiology Immunology, Feinberg School of Medicine, Children s Memorial Hospital, Northwestern University, Chicago, Illinois 60611, USA
J Infect Dis 190:856-65. 2004..The etiology is unknown, but a ubiquitous infectious agent appears to be likely. Immunoglobulin A plasma cells infiltrate inflamed tissues in acute KD, producing oligoclonal, antigen-driven antibodies...
CD8 T lymphocytes do not express cytotoxic proteins in coronary artery aneurysms in acute Kawasaki diseaseJudith A Guzman-Cottrill
Division of Infectious Diseases, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL, USA
Pediatr Infect Dis J 24:382-4. 2005..We speculate that the etiologic agent of KD interferes with expression of these cytotoxic proteins by CD8 T lymphocytes, prolonging inflammation in the arterial wall and leading to coronary artery aneurysm formation...
Ultrastructural, immunofluorescence, and RNA evidence support the hypothesis of a "new" virus associated with Kawasaki diseaseAnne H Rowley
Department of Pediatrics, Feinberg School of Medicine, Children s Memorial Hospital, Northwestern University, Chicago, Illinois 60611, USA
J Infect Dis 203:1021-30. 2011....
Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki diseaseMasaru Miura
Department of Pediatrics, Northwestern University, The Feinberg School of Medicine, Chicago, IL, USA
Pediatr Infect Dis J 24:927-9. 2005..Antigen was not detected in kidney from 6 patients. The presence of antigen may be related to gastrointestinal pathology in acute Kawasaki disease...
Cell adhesion molecule expression in coronary artery aneurysms in acute Kawasaki diseaseMasaru Miura
Department of Pediatrics, Northwestern University, The Feinberg School of Medicine and The Children's Memorial Hospital, Chicago, IL, USA
Pediatr Infect Dis J 23:931-6. 2004..Our results suggest that E-selectin and VCAM-1 expression on neovasculature may contribute to neoangiogenesis and prolonged CAA inflammation and that integrin beta1 might be involved in fibroblastic remodeling of acute KD CAA...
Pathogenesis and management of Kawasaki diseaseAnne H Rowley
Northwestern University Feinberg School of Medicine, Pediatrics, Morton 4 685B, 310 E Superior St, Chicago, IL 60611, USA
Expert Rev Anti Infect Ther 8:197-203. 2010..Acute coronary obstruction requires acute thrombolytic therapy with a surgical or percutaneous interventional procedure...
Kawasaki disease: novel insights into etiology and genetic susceptibilityAnne H Rowley
Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Annu Rev Med 62:69-77. 2011..S. children. Identification of the etiologic agent and of genes conferring KD susceptibility are the best means of improving diagnosis and therapy and enabling prevention of this important disorder of childhood...
Macrophage infiltration of pancreatic acini and islets in acute Kawasaki diseaseMasaru Miura
Department of Pediatrics, Northwestern University, Chicago, IL 60611, USA
Pediatr Infect Dis J 22:1106-8. 2003..Three of 10 acute fatal KD cases had diffuse macrophage infiltration of the pancreas; T cells were not prominent. Affected islets were seen in close proximity to normal islets. These findings may explain the rarity of diabetes after KD...
Human coronavirus NL63 is not detected in the respiratory tracts of children with acute Kawasaki diseaseChisato Shimizu
Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, 92093, USA
J Infect Dis 192:1767-71. 2005..Only 1 (2%) of 48 patients with acute KD was positive by RT-PCR for HCoV-NL63/NH in a nasopharyngeal swab. These data do not support an association between these HCoVs and KD...
Inflammatory pulmonary nodules in Kawasaki diseaseAlexandra F Freeman
Department of Pediatrics, Feinberg School of Medicine, Chicago, Illinois, USA
Pediatr Pulmonol 36:102-6. 2003..Recognition of this pulmonary complication of KD may enable cautious observation of such lesions for spontaneous resolution...
Advances in Kawasaki diseaseStanford T Shulman
Division of Infectious Diseases, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, 2300 Children s Plaza, Box 20, Chicago, IL 60614, USA
Eur J Pediatr 163:285-91. 2004....
Systemic arterial expression of matrix metalloproteinases 2 and 9 in acute Kawasaki diseasePatrick J Gavin
Division of Infectious Disease, Children's Memorial Hospital, Chicago, Ill, USA
Arterioscler Thromb Vasc Biol 23:576-81. 2003..Systemic arterial expression of MMP-9 in acute KD, even in the absence of inflammatory changes in the vessel, suggests induction by a circulating factor, or possibly by an infectious agent with tropism for arterial tissue...
Recent advances in the understanding and management of kawasaki diseaseAnne H Rowley
Department of Pediatrics, Northwestern University Feinberg School of Medicine, Morton 4 685B, 310 East Superior Street, Chicago, IL, 60611, USA
Curr Infect Dis Rep 12:96-102. 2010..Additional data regarding KD pathogenesis are urgently needed to provide other targets for therapy for those patients at highest risk of developing coronary artery abnormalities...
Incomplete (atypical) Kawasaki diseaseAnne H Rowley
Northwestern University Medical School, Chicago, IL, USA
Pediatr Infect Dis J 21:563-5. 2002
Summary and abstracts of the Seventh International Kawasaki Disease Symposium: December 4-7, 2001, Hakone, JapanJane W Newburger
Children's Hospital, Harvard University, Boston, Massachusetts, USA
Pediatr Res 53:153-7. 2003
Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the CoWalter Wilson
Mayo Clinic, USA
Circulation 116:1736-54. 2007..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis that were last published in 1997...
Finding the cause of Kawasaki disease: a pediatric infectious diseases research priorityAnne H Rowley
J Infect Dis 194:1635-7. 2006
Systemic production of vascular endothelial growth factor and fms-like tyrosine kinase-1 receptor in acute Kawasaki diseaseKumi Yasukawa
Department of Pediatrics, Kawasaki Seitetsu Hospital, Chiba, Japan
Circulation 105:766-9. 2002..Increased vascular permeability is an important event during the initial process of Kawasaki disease (KD). One potential responsible candidate for the induction of vascular hyperpermeability is vascular endothelial growth factor (VEGF)...
