Mary E Rinella

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint The role of diet and nutrient composition in nonalcoholic Fatty liver disease
    Erin Marie McCarthy
    Northwestern Faculty Foundation, Chicago, IL, USA
    J Acad Nutr Diet 112:401-9. 2012
  2. ncbi request reprint Dual-echo, chemical shift gradient-echo magnetic resonance imaging to quantify hepatic steatosis: Implications for living liver donation
    Mary E Rinella
    Department of Medicine, Northwestern University Medical School, Chicago, IL 60611, USA
    Liver Transpl 9:851-6. 2003
  3. ncbi request reprint The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
    Mary E Rinella
    Northwestern University Feinberg School of Medicine, Division of Hepatology, 303 E Chicago Ave, Searle 10 567, Chicago, IL 60611, USA
    J Hepatol 40:47-51. 2004
  4. pmc Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet
    Mary E Rinella
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Lipid Res 49:1068-76. 2008
  5. pmc Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis
    Mary E Rinella
    Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Hepatology 54:1600-9. 2011
  6. ncbi request reprint Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial
    Lisa B Van Wagner
    Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Ann Hepatol 10:277-86. 2011
  7. doi request reprint A myriad of pathways to NASH
    Soledad Larraín
    Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Clin Liver Dis 16:525-48. 2012
  8. pmc Hepatic overexpression of abcb11 promotes hypercholesterolemia and obesity in mice
    Anne S Henkel
    Division of Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Gastroenterology 141:1404-11, 1411.e1-2. 2011
  9. doi request reprint Patients transplanted for nonalcoholic steatohepatitis are at increased risk for postoperative cardiovascular events
    Lisa B Vanwagner
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Hepatology 56:1741-50. 2012
  10. doi request reprint Non-alcoholic fatty liver disease: is bariatric surgery the answer?
    Anjana A Pillai
    Department of Transplant Surgery, Northwestern University, Feinberg School of Medicine, 675 N St Clair Avenue, Galter 17 200, Chicago, IL 60611, USA
    Clin Liver Dis 13:689-710. 2009

Research Grants

  1. Mechanisms of Non-Alcoholic Steatohepatitis
    Mary Rinella; Fiscal Year: 2007

Collaborators

Detail Information

Publications12

  1. doi request reprint The role of diet and nutrient composition in nonalcoholic Fatty liver disease
    Erin Marie McCarthy
    Northwestern Faculty Foundation, Chicago, IL, USA
    J Acad Nutr Diet 112:401-9. 2012
    ....
  2. ncbi request reprint Dual-echo, chemical shift gradient-echo magnetic resonance imaging to quantify hepatic steatosis: Implications for living liver donation
    Mary E Rinella
    Department of Medicine, Northwestern University Medical School, Chicago, IL 60611, USA
    Liver Transpl 9:851-6. 2003
    ..Fat saturation added to the MRI protocol may further improve diagnostic accuracy. This technique may be applicable to the larger population with hepatic steatosis...
  3. ncbi request reprint The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
    Mary E Rinella
    Northwestern University Feinberg School of Medicine, Division of Hepatology, 303 E Chicago Ave, Searle 10 567, Chicago, IL 60611, USA
    J Hepatol 40:47-51. 2004
    ..Mice fed a methionine-choline deficient (MCD) diet develop steatohepatitis, however the influence of insulin in this model is unknown...
  4. pmc Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet
    Mary E Rinella
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Lipid Res 49:1068-76. 2008
    ..Feeding the MCD diet to diabetic rodents broadens the applicability of this model for the study of human NASH...
  5. pmc Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis
    Mary E Rinella
    Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Hepatology 54:1600-9. 2011
    ..Interestingly, whereas pharmacologic JNK inhibition did not prevent the development of MCD diet-induced steatohepatitis, it did attenuate UPR and downstream inflammatory signaling...
  6. ncbi request reprint Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial
    Lisa B Van Wagner
    Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Ann Hepatol 10:277-86. 2011
    ..Pilot studies suggest that pentoxifylline (PTX) can reduce liver injury in patients with NASH...
  7. doi request reprint A myriad of pathways to NASH
    Soledad Larraín
    Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Clin Liver Dis 16:525-48. 2012
    ....
  8. pmc Hepatic overexpression of abcb11 promotes hypercholesterolemia and obesity in mice
    Anne S Henkel
    Division of Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Gastroenterology 141:1404-11, 1411.e1-2. 2011
    ..We investigated whether overexpression of Abcb11 in mice increases lipid absorption in the intestine and affects the development of obesity or hypercholesterolemia...
  9. doi request reprint Patients transplanted for nonalcoholic steatohepatitis are at increased risk for postoperative cardiovascular events
    Lisa B Vanwagner
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Hepatology 56:1741-50. 2012
    ..90). The majority (70%) of events occurred in the perioperative period, and the occurrence of a CV event was associated with a 50% overall mortality. However, there were no differences in patient, graft, or CV mortality between groups...
  10. doi request reprint Non-alcoholic fatty liver disease: is bariatric surgery the answer?
    Anjana A Pillai
    Department of Transplant Surgery, Northwestern University, Feinberg School of Medicine, 675 N St Clair Avenue, Galter 17 200, Chicago, IL 60611, USA
    Clin Liver Dis 13:689-710. 2009
    ..This review focuses on the potential risks and benefits of bariatric surgery in subjects with NAFLD and explores its role in the management of NASH in the obese patient...
  11. pmc The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis
    Lisa B Van Wagner
    Northwestern University Feinberg School of Medicine, 251 East Huron Street, Galter Pavilion, Suite 3 150, Chicago, IL 60611, USA
    Therap Adv Gastroenterol 4:249-63. 2011
    ..Finally, we will summarize the available clinical data and review both the risks and benefits of insulin sensitizers in the treatment of NASH...
  12. ncbi request reprint Liver biopsy in living donors
    Mary E Rinella
    Liver Transpl 8:1123-5. 2002

Research Grants2

  1. Mechanisms of Non-Alcoholic Steatohepatitis
    Mary Rinella; Fiscal Year: 2007
    ..We hope that insight gained from this work will identify factors responsible for the development of NASH that will guide future experiments and ultimately therapy in human NASH. ..