Janardan Reddy

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
    Sean R Pyper
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    PPAR Res 2010:. 2010
  2. pmc PPARalpha: energy combustion, hypolipidemia, inflammation and cancer
    Sean R Pyper
    Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Nucl Recept Signal 8:e002. 2010
  3. pmc Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse
    Kojiro Matsumoto
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Carcinogenesis 31:318-25. 2010
  4. pmc Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice
    Jiansheng Huang
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    FASEB J 26:628-38. 2012
  5. ncbi request reprint Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system
    J K Reddy
    Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Annu Rev Nutr 21:193-230. 2001
  6. pmc Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: biotic and xenobiotic sensing
    Janardan K Reddy
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Pathol 164:2305-21. 2004
  7. ncbi request reprint Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation
    Janardan K Reddy
    Department of Pathology, Feinberg School of Medicine, Northwestern University, 303 E Chicago Avenue, Chicago, IL 60611 3008, USA
    Am J Physiol Gastrointest Liver Physiol 290:G852-8. 2006
  8. ncbi request reprint Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis
    J K Reddy
    Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611 3008, USA
    Am J Physiol Gastrointest Liver Physiol 281:G1333-9. 2001
  9. ncbi request reprint Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver
    Dongsheng Guo
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 282:36766-76. 2007
  10. ncbi request reprint PPARalpha in the pathogenesis of fatty liver disease
    M Sambasiva Rao
    Hepatology 40:783-6. 2004

Research Grants

  1. Transcriptional Coactivators in Liver Function
    Janardan K Reddy; Fiscal Year: 2010
  2. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2009
  3. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2002
  4. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2002
  5. FASEB Conference: Mechanisms of Liver Growth and Disease
    Janardan Reddy; Fiscal Year: 2002
  6. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2001
  7. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2000
  8. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2000
  9. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 1999
  10. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2003

Collaborators

Detail Information

Publications45

  1. pmc PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
    Sean R Pyper
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    PPAR Res 2010:. 2010
    ....
  2. pmc PPARalpha: energy combustion, hypolipidemia, inflammation and cancer
    Sean R Pyper
    Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Nucl Recept Signal 8:e002. 2010
    ..PPARalpha requires transcription coactivator PPAR-binding protein (PBP)/mediator subunit 1(MED1) for its transcriptional activity...
  3. pmc Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse
    Kojiro Matsumoto
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Carcinogenesis 31:318-25. 2010
    ..These results indicate that PBP/MED1 is essential for the development of HCC in the mouse...
  4. pmc Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice
    Jiansheng Huang
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    FASEB J 26:628-38. 2012
    ....
  5. ncbi request reprint Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system
    J K Reddy
    Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Annu Rev Nutr 21:193-230. 2001
    ....
  6. pmc Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: biotic and xenobiotic sensing
    Janardan K Reddy
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Pathol 164:2305-21. 2004
  7. ncbi request reprint Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation
    Janardan K Reddy
    Department of Pathology, Feinberg School of Medicine, Northwestern University, 303 E Chicago Avenue, Chicago, IL 60611 3008, USA
    Am J Physiol Gastrointest Liver Physiol 290:G852-8. 2006
    ..Delineation of the pathogenetic aspects of FLD is necessary for developing novel therapeutic strategies for this disease...
  8. ncbi request reprint Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis
    J K Reddy
    Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611 3008, USA
    Am J Physiol Gastrointest Liver Physiol 281:G1333-9. 2001
    ....
  9. ncbi request reprint Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver
    Dongsheng Guo
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 282:36766-76. 2007
    ..These observations, therefore, provide information for the first time to indicate that PPARalpha ligands not only serve as PPARalpha agonists but possibly act as CAR antagonists...
  10. ncbi request reprint PPARalpha in the pathogenesis of fatty liver disease
    M Sambasiva Rao
    Hepatology 40:783-6. 2004
  11. ncbi request reprint Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver
    Songtao Yu
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Biochimie 86:743-61. 2004
    ..The identification of these and other novel PPARgamma-target genes should provide a basis for understanding the molecular mechanisms underlying energy storage and lipid homeostasis...
  12. pmc Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator
    Sailesh Surapureddi
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 99:11836-41. 2002
    ..The composition of this complex may provide insight into the basis of tissue and species sensitivity to peroxisome proliferators...
  13. pmc Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity
    Yuzhi Jia
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 102:12531-6. 2005
    ..We conclude that transcription coactivator PBP/TRAP220/MED1 is involved in the regulation of hepatic CAR function and that PBP deficiency in liver abrogates acetaminophen hepatotoxicity...
  14. ncbi request reprint Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver
    Dongsheng Guo
    The Department of Pathology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Biochem Biophys Res Commun 347:485-95. 2006
    ....
  15. ncbi request reprint Pancreatic stem cells: differentiation options
    M Sambasiva Rao
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Stem Cell Rev 1:265-71. 2005
  16. pmc Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members
    Jun Xia
    Department of Cell and Development Biology, University of Illinois at Urbana Champaign, Urbana, IL 60801, USA
    Arch Biochem Biophys 468:49-57. 2007
    ..SRC-3 alone of the p160 coactivators enhanced CAR transactivation in hepatic cells without PB treatment...
  17. ncbi request reprint Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver
    Joy Sarkar
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Gene Expr 13:255-69. 2007
    ..The dependence of PPARalpha- and CAR-regulated gene transcription on coactivator PBP but not on PRIP attests to the existence of coactivator selectivity in nuclear receptor function...
  18. pmc Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation
    Ruiyin Chu
    Department of Functional Genomics, Aventis Pharmaceuticals, Inc, Bridgewater, New Jersey 08807, USA
    Mol Cell Biol 24:6288-97. 2004
    ..We conclude that livers with PPARalpha activation are transcriptionally geared towards fatty acid combustion...
  19. ncbi request reprint Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver
    Yuzhi Jia
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Illinois 60611 3008, USA
    J Biol Chem 279:24427-34. 2004
    ..In essence, the absence of PBP in hepatocytes in vivo appears to mimic the absence of PPARalpha, indicating that coactivator PBP is essential for PPARalpha-regulated gene expression in liver parenchymal cells...
  20. ncbi request reprint Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-ox
    Yuzhi Jia
    Department of Pathology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611 3008, USA
    J Biol Chem 278:47232-9. 2003
    ....
  21. ncbi request reprint Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen
    Kirstin Meyer
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Carcinogenesis 24:975-84. 2003
    ....
  22. ncbi request reprint Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
    Songtao Yu
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 278:498-505. 2003
    ..We conclude that excess PPARgamma activity can lead to the development of a novel type of adipogenic hepatic steatosis...
  23. ncbi request reprint Coactivator PRIP, the peroxisome proliferator-activated receptor-interacting protein, is a modulator of placental, cardiac, hepatic, and embryonic development
    Yi Jun Zhu
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 278:1986-90. 2003
    ..These observations indicate that PRIP like PBP, CBP, and p300 is an essential and nonredundant coactivator...
  24. ncbi request reprint Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis
    Songtao Yu
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Curr Mol Med 3:561-72. 2003
    ..In addition, mice lacking AOX developed steatohepatitis and provided clues regarding the molecular mechanism responsible for steatosis and steatohepatitis and the role of unmetabolized AOX substrates in the activation of PPAR alpha...
  25. ncbi request reprint Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors
    Susan E Crawford
    Department of Pathology, Northwestern University School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 277:3585-92. 2002
    ..These observations identify the GATA family of transcription factors as a new interacting partner of PBP and demonstrate that PBP is essential for normal development of vital organ systems...
  26. ncbi request reprint Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators
    Ivan Rusyn
    Laboratory of Environmental Genomics, Department of Environmental Sciences and Engineering, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599, USA
    Cancer Res 64:1050-7. 2004
    ....
  27. ncbi request reprint Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage
    Douglas E Hughes
    University of Illinois at Chicago, College of Medicine, Department of Molecular Genetics, Chicago, IL 60607 7170, USA
    Hepatology 37:1414-24. 2003
    ....
  28. pmc The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma
    Hui Li
    Department of Microbiology and Immunology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Biol Chem 283:13077-86. 2008
    ..Last, an ERK-regulated site in Med1 protein is also essential for up-regulating IFN-induced transcription although not critical for binding to C/EBP-beta...
  29. pmc Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha
    Sailesh Surapureddi
    Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Mol Pharmacol 74:913-23. 2008
    ..We conclude that the coactivator NCOA6 mediates the mechanism of the synergistic activation of the CYP2C9 gene by CAR and HNF4alpha...
  30. ncbi request reprint Phosphorylation of transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP). Stimulation of transcriptional regulation by mitogen-activated protein kinase
    Parimal Misra
    Department of Pathology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    J Biol Chem 277:48745-54. 2002
    ..The functional role of PKA and PKC phosphorylation sites in PBP remains to be elucidated...
  31. ncbi request reprint Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip Biology System
    Ruiyin Chu
    Department of Functional Genomics, Aventis Pharmaceuticals, Inc, Bridgewater, NJ 08807, USA
    Gene Expr 10:165-77. 2002
    ..This SELDI method offers several technical advantages for detection of differentially expressed proteins, including ease and speed of screening, no need for chromatographic processing, and small sample size...
  32. ncbi request reprint Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation
    Parimal Misra
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    J Biol Chem 277:20011-9. 2002
    ....
  33. ncbi request reprint PAT5A: a partial agonist of peroxisome proliferator-activated receptor gamma is a potent antidiabetic thiazolidinedione yet weakly adipogenic
    Parimal Misra
    Discovery Research, Dr Reddy s Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad, India
    J Pharmacol Exp Ther 306:763-71. 2003
    ..These biological effects suggest that PAT5A is a PPARgamma modulator that activates some (insulin sensitization), but not all (adipogenesis), PPARgamma-signaling pathways...
  34. ncbi request reprint Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis
    Chao Qi
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 278:25281-4. 2003
    ..These data indicate that PRIP, like PBP, is a downstream regulator of PPARgamma-mediated adipogenesis and that both these coactivators are required for the successful completion of adipogenic program...
  35. ncbi request reprint Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A, in mouse liver by peroxisome proliferator-activated receptor alpha and gamma
    Navin Viswakarma
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Biol Chem 282:18613-24. 2007
    ..The induction of Cidea in liver with these PPARalpha and -gamma agonists suggests a possible role for Cidea in energy metabolism and a less likely role in hepatocyte apoptosis...
  36. ncbi request reprint EDGE: a centralized resource for the comparison, analysis, and distribution of toxicogenomic information
    Kevin R Hayes
    McArdle Laboratory for Cancer Research, 1400 University Avenue, Madison, WI 53706, USA
    Mol Pharmacol 67:1360-8. 2005
    ..We propose that EDGE can serve as a prototype resource for the sharing of toxicogenomics information and be used to develop algorithms for efficient chemical classification and hazard prediction...
  37. ncbi request reprint Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression
    David Patsouris
    Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, P O Box 8129, 6700 EV, Wageningen, The Netherlands
    Endocrinology 147:1508-16. 2006
    ..It is concluded that 1) PPARalpha and PPARalpha-signaling are activated in liver by chronic high-fat feeding; and 2) PPARgamma may compensate for PPARalpha in PPARalpha null mice on HFD...
  38. pmc Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis
    Keiichirou Morimura
    Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Carcinogenesis 27:1074-80. 2006
    ..This mouse model will be useful for human cancer risk assessment of PPARalpha ligands...
  39. ncbi request reprint Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance
    Zhiyong Wang
    Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Cell Metab 3:111-22. 2006
    ..They exhibit increased basal metabolic rates and heightened levels of physical activity. Therefore, p/CIP and SRC-1 play critical roles in energy balance by controlling both energy intake and energy expenditure...
  40. ncbi request reprint PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex
    Sailesh Surapureddi
    The Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Biochem Biophys Res Commun 343:535-43. 2006
    ..We conclude that ciprofibrate, a PPARalpha ligand, binds a multiprotein complex and PRIC320 cloned from this complex functions as a nuclear receptor coactivator...
  41. ncbi request reprint Upregulation of calpastatin in regenerating and developing rat liver: role in resistance against hepatotoxicity
    Pallavi B Limaye
    Department of Toxicology, College of Pharmacy, The University of Louisiana at Monroe, Monroe, LA 71209 0495, USA
    Hepatology 44:379-88. 2006
    ..In conclusion, CAST overexpression could be used as a therapeutic strategy to prevent progression of liver injury where liver regeneration is severely hampered...
  42. ncbi request reprint Transcription coactivators for peroxisome proliferator-activated receptors
    Songtao Yu
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Biochim Biophys Acta 1771:936-51. 2007
    ..Identification of PPAR specific coactivators should further our understanding of the complexities of metabolic diseases associated with energy metabolism...
  43. ncbi request reprint Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development
    Kojiro Matsumoto
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    J Biol Chem 282:17053-60. 2007
    ..These studies provide direct evidence in support of a critical role of PBP/TRAP220 in liver regeneration, induction of hepatotoxicity, and hepatocarcinogenesis...
  44. pmc Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene
    David Oaxaca-Castillo
    INSERM, U866, Dijon F 21000, France
    Biochem Biophys Res Commun 360:314-9. 2007
    ..ACOX1a seems to be more labile and exhibits only 50% specific activity toward palmitoyl-CoA as compared to ACOX1b...

Research Grants47

  1. Transcriptional Coactivators in Liver Function
    Janardan K Reddy; Fiscal Year: 2010
    ..They should provide a rational basis for testing strategies to regulate gene expression. ..
  2. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2009
    ..They should provide a rational basis for testing strategies to regulate gene expression. ..
  3. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2002
    ....
  4. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2002
    ..abstract_text> ..
  5. FASEB Conference: Mechanisms of Liver Growth and Disease
    Janardan Reddy; Fiscal Year: 2002
    ..abstract_text> ..
  6. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2001
    ....
  7. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2000
    ....
  8. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 2000
    ....
  9. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 1999
    ....
  10. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2003
    ..abstract_text> ..
  11. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2003
    ..abstract_text> ..
  12. Biologic Studies with Peroxisome Proliferators and PPARs
    Janardan Reddy; Fiscal Year: 2007
    ..The studies we now propose will generate new information, which can provide insights into the molecular complexity and the functional implications of PPAR regulated gene expression in liver. ..
  13. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2007
    ..abstract_text> ..
  14. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2006
    ..abstract_text> ..
  15. Biologic Studies with Peroxisome Proliferators and PPARs
    Janardan Reddy; Fiscal Year: 2006
    ..The studies we now propose will generate new information, which can provide insights into the molecular complexity and the functional implications of PPAR regulated gene expression in liver. ..
  16. Biologic Studies with Peroxisome Proliferators and PPARs
    Janardan Reddy; Fiscal Year: 2005
    ..The studies we now propose will generate new information, which can provide insights into the molecular complexity and the functional implications of PPAR regulated gene expression in liver. ..
  17. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2005
    ..abstract_text> ..
  18. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2004
    ..abstract_text> ..
  19. HEPATOCYTE DIFFERENTIATION IN PANCREAS
    Janardan Reddy; Fiscal Year: 1991
    ..We anticipate that the highly reproducible and clearly characterized model of pancreatic hepatocyte differentiation will most likely yield information of a fundamental nature regarding cell commitment and differentiation...
  20. HEPATOCYTE DIFFERENTIATION IN PANCREAS
    Janardan Reddy; Fiscal Year: 1990
  21. HEPATOCYTE DIFFERENTIATION IN PANCREAS
    Janardan Reddy; Fiscal Year: 1992
    ..We anticipate that the highly reproducible and clearly characterized model of pancreatic hepatocyte differentiation will most likely yield information of a fundamental nature regarding cell commitment and differentiation...
  22. HEPATOCYTE DIFFERENTIATION IN PANCREAS
    Janardan Reddy; Fiscal Year: 1993
    ..We anticipate that the highly reproducible and clearly characterized model of pancreatic hepatocyte differentiation will most likely yield information of a fundamental nature regarding cell commitment and differentiation...
  23. BIOLOGIC STUDIES WITH LIVER PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 1980
    ..The information obtained from these studies should further our knowledge of peroxisomes as well as allow us to recognize the implications of the multiplicity of biologic effects of peroxisome proliferators...
  24. IDENTIFICATION OF LIVER STEM CELLS IN PANCREAS
    Janardan Reddy; Fiscal Year: 1999
    ....
  25. BIOLOGICAL STUDIES WITH PEROXISOME PROLIFERATORS
    Janardan Reddy; Fiscal Year: 2001
    ..abstract_text> ..
  26. Transcriptional Coactivators in Liver Function
    Janardan Reddy; Fiscal Year: 2004
    ..abstract_text> ..