Research Topics
Genomes and GenesSpecies | R Ramsey-GoldmanSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Telomere length in patients with systemic lupus erythematosus and its associations with carotid plaqueCarly Skamra
Division of Rheumatology, Northwestern University Feinberg School of Medicine, 240 E Huron, Suite M300, Chicago, IL 60611, USA
Rheumatology (Oxford) 52:1101-8. 2013..Only older age but not shorter TL was independently associated with carotid plaque. Additional studies are needed to confirm if TL is a novel biomarker for cardiovascular disease in SLE...
Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosusSudeshna Dasgupta
Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA
BMC Med Genet 12:7. 2011....
Does hormone replacement therapy affect disease activity in patients with systemic lupus erythematosus?Rosalind Ramsey-Goldman
Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Nat Clin Pract Rheumatol 1:72-3. 2005- Time to seizure occurrence and damage in PROFILE, a multi-ethnic systemic lupus erythematosus cohortR Ramsey-Goldman
Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Lupus 17:177-84. 2008..7; 95% CI 1.0-7.0) or an episode of psychosis (HR = 4.7; 95% CI 2.3-9.9). No allele from the candidate genes examined (HLA-DRB1, HLA-DQB1, FCGR2A, FCGR3A, or FCG3B) predicted clinical seizures or damage caused by seizures... - Fatigue in systemic lupus erythematosus and rheumatoid arthritisRosalind Ramsey-Goldman
Department of Medicine, 240 E Huron, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
PM R 2:384-92. 2010..Analyses and interpretation of data have been hindered by variability in the reliability and validity of fatigue measures. Empirically based fatigue treatment guidelines are needed in both conditions... - Factors associated with arterial vascular events in PROFILE: a Multiethnic Lupus CohortA M Bertoli
Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA
Lupus 18:958-65. 2009..Awareness of these factors should lead to more effective management strategies of patients at risk for arterial vascular events... - Baseline characteristics of a multiethnic lupus cohort: PROFILEG S Alarcon
Department of Medicine, University of Alabama, Birmingham 35294, USA
Lupus 11:95-101. 2002..To report the baseline characteristics of a US multi-ethnic, multi-regional, multi-institution cohort of patients with systemic lupus erythematosus (SLE) and how it was constituted... - Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African AmericansJ E Salmon
Department of Medicine, Graduate Program in Immunology, The Cornell University Medical College, New York 10021, USA
J Clin Invest 97:1348-54. 1996..The skewing in the distribution of Fc gamma RIIA alleles identifies this gene as a risk factor with pathophysiologic importance for the SLE diathesis in African Americans... - Disease damage and low bone mineral density: an analysis of women with systemic lupus erythematosus ever and never receiving corticosteroidsC Lee
Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Rheumatology (Oxford) 45:53-60. 2006..To evaluate the relationship between disease damage and bone mineral density (BMD) in women with systemic lupus erythematosus (SLE)... - Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivityA Ippolito
Division of Rheumatology, Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21205, USA
Lupus 20:250-5. 2011..Variation in the results for complement, however, is more likely to be explained by response to treatment. These findings deserve consideration in the context of diagnosis and enrolment in clinical trials... - Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosusJ G Hanly
Department of Medicine, Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Ann Rheum Dis 70:1726-32. 2011..This study examined a disease inception cohort of 1047 SLE patients to determine which autoantibodies at enrolment predicted subsequent neuropsychiatric events... - Association of osteoporosis and cardiovascular disease in women with systemic lupus erythematosusR Ramsey-Goldman
Northwestern University Medical School, Chicago, Illinois, USA
Arthritis Rheum 44:2338-41. 2001..55 (P = 0.05). CONCLUSION: These results demonstrate an association between decreased BMD and both an increased carotid plaque index and presence of coronary artery calcification in a small cohort of young women with lupus... - Review of ACR hematologic criteria in systemic lupus erythematosusA H Kao
Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, PA, USA
Lupus 13:865-8. 2004..Despite these limitations, the SLICC committee recommends no change in the elements of the hematologic criterion when this criterion is properly interpreted and other causes of cytopenia are excluded... - Validation of a Systemic Lupus Activity Questionnaire (SLAQ) for population studiesE W Karlson
Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Robert B. Brigham Arthritis and Musculoskeletal Clinical Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Lupus 12:280-6. 2003..In studies of SLE, symptoms suggesting disease can be screened by self-report using the SLAQ and then verified by further evaluation... - Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohortGraciela S Alarcon
Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
PLoS Med 3:e396. 2006..The purpose of this study was to determine the factors predicting the development of renal involvement and its progression to ESRD in a multi-ethnic SLE cohort (PROFILE)... - Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosusF Yesim K Demirci
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Rheumatol 34:1708-11. 2007..We investigated the association of TLR5 (Arg392Stop, rs5744168) and TLR9 (-1237T-->C, rs5743836) single nucleotide polymorphisms (SNP) with systemic lupus erythematosus (SLE) in Caucasian American subjects... - Self-reported fractures and associated factors in women with systemic lupus erythematosusChin Lee
Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Rheumatol 34:2018-23. 2007..To determine the frequency of fractures and associated factors in women with systemic lupus erythematosus (SLE)... - Homocysteine, bone mineral density, and fracture risk over 2 years of followup in women with and without systemic lupus erythematosusElisa Y Rhew
Department of Medicine, Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Rheumatol 35:230-6. 2008..To examine the relationship of baseline homocysteine levels with bone mineral density (BMD) and incidence of fractures over 2 years in women with and without systemic lupus erythematosus (SLE)... - Malignancy and systemic lupus erythematosusSasha Bernatsky
Northwestern University, Division of Rheumatology, Arthritis, Ward 3-315, 303 East Chicago Avenue, Chicago, IL 60611-3088, USA
Curr Rheumatol Rep 4:351-8. 2002..The recommendations advocated for cancer screening policies and for minimizing known risk factors for cancer in the general population should not be neglected in persons with SLE... - Association between African American race/ethnicity and low bone mineral density in women with systemic lupus erythematosusChin Lee
Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
Arthritis Rheum 57:585-92. 2007..To determine the association between race/ethnicity and bone mineral density (BMD) in women with systemic lupus erythematosus (SLE)... - Premature atherosclerotic disease in systemic lupus erythematosus--role of inflammatory mechanismsElisa Y Rhew
Division of Rheumatology Northwestern University, Feinberg School of Medicine, 240 E Huron St Suite M300 Chicago, IL 60611, USA
Autoimmun Rev 5:101-5. 2006..In this article, we present a case of a young woman with SLE who presents with chest pain, followed by a review of inflammation-based pathogenic mechanisms that are shared by SLE and atherosclerotic cardiovascular disease... - The rate and pattern of organ damage in late onset systemic lupus erythematosusPeter Maddison
School of Sport, Health and Exercise Science, University of Wales, Bangor, UK
J Rheumatol 29:913-7. 2002..Also, the pattern of damage is different, but whether this reflects age per se or the effect of the disease in the elderly remains to be established... - US incidence of juvenile dermatomyositis, 1995-1998: results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases RegistryEduardo P Mendez
Children's Memorial Hospital, Chicago, Illinois, USA
Arthritis Rheum 49:300-5. 2003..3:1). CONCLUSION: This study provides evidence for sex, and possibly racial differences in the risk of juvenile DM in the US... - Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosusMichelle A Petri
Johns Hopkins University Medical Center, Baltimore, Maryland 21205, USA
Arthritis Rheum 50:2858-68. 2004..To determine whether prasterone administration results in improvement or stabilization of systemic lupus erythematosus (SLE) disease activity and its symptoms... - History of infection before the onset of juvenile dermatomyositis: results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Research RegistryLauren M Pachman
The Northwestern University s Feinberg School of Medicine, Chicago, Illinois 60614, USA
Arthritis Rheum 53:166-72. 2005..To obtain data concerning a history of infection occurring in the 3 months before recognition of the typical weakness and rash associated with juvenile dermatomyositis (JDM)... - Osteoporosis in systemic lupus erythematosus mechanismsChin Lee
Division of Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Rheum Dis Clin North Am 31:363-85, viii. 2005..This article reviews the current epidemiologic information available on osteoporosis and fracture data in SLE and discusses evaluation and management strategies pertinent to patients who have lupus... - An osteoporosis and fracture intervention program increases the diagnosis and treatment for osteoporosis for patients with minimal trauma fracturesBeatrice J Edwards
Bone Health and Osteoporosis Program, Feinberg School of Medicine, Northwestern University, Chicago, USA
Jt Comm J Qual Patient Saf 31:267-74. 2005..As fewer than 25% of patients with an osteoporotic minimal trauma fracture (MTF) are evaluated and treated for osteoporosis, an osteoporosis and fracture intervention program (OFIP) was developed... - Revisiting the issue of malignancy risk in systemic lupus erythematosusSasha Bernatsky
Division of Clinical Epidemiology, Montreal General Hospital Research Institute, Quebec, Canada
Curr Rheumatol Rep 7:476-81. 2005..This and other works in progress will, it is hoped, considerably advance the knowledge regarding the association between autoimmune diseases and malignancy... - Bone health and systemic lupus erythematosusChin Lee
Northwestern University, Feinberg School of Medicine, Division of Rheumatology, McGaw Pavilion 2300, Chicago, IL 60611, USA
Curr Rheumatol Rep 7:482-9. 2005..This paper discusses recent epidemiologic information related to osteoporosis and fractures in SLE, and highlights relevant developments regarding evaluation and treatment of patients at risk for bone loss... - Duration of illness is an important variable for untreated children with juvenile dermatomyositisLauren M Pachman
Department of Pediatrics, Division of Immunology/Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
J Pediatr 148:247-53. 2006..01 for each). CONCLUSIONS: Duration of untreated symptoms is an important variable and should be included in decisions concerning both diagnostic criteria and intensity of therapy for children with JDM... - Can morbidity and mortality of SLE be improved?Anurekha Bongu
Rheumatology, Northwestern University Medical School, Arthritis, Ward 3 315, 303 E Chicago Ave, Chicago, IL 60611, USA
Best Pract Res Clin Rheumatol 16:313-32. 2002.... - Missed opportunities in physician management of glucocorticoid-induced osteoporosis?Rosalind Ramsey-Goldman
Arthritis Rheum 46:3115-20. 2002 - Cancer screening in patients with systemic lupus erythematosusSasha R Bernatsky
Montreal General Hospital Research Institute, the Department of Rheumatology and the Divisions of Clinical Immunology and Allergy and Clinical Epidemiology, Montreal General Hospital, McGill University Health Centre, Montreal, Canada
J Rheumatol 33:45-9. 2006..CONCLUSION: These data suggest that appropriate cancer screening may be overlooked in patients with SLE... - Do traditional Gail model risk factors account for increased breast cancer in women with lupus?Sasha Bernatsky
Division of Clinical Epidemiology, Department of Oncology, Montreal General Hospital, Montreal, Quebec, Canada
J Rheumatol 30:1505-7. 2003..To determine to what extent the observed experience of breast cancer in a combined cohort of patients with systemic lupus erythematosus (SLE) could be explained by the profile of breast cancer risk factors... - Risk of lymphoma in autoimmune rheumatic conditionsSasha Bernatsky
Arch Intern Med 166:1233-4; author reply 1234. 2006 - Abetimus sodium for renal flare in systemic lupus erythematosus: results of a randomized, controlled phase III trialMario H Cardiel
Hospital General Dr Miguel Silva, Morelia, Michoacan, Mexico
Arthritis Rheum 58:2470-80. 2008.... - Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosomeR Hal Scofield
Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Oklahoma City VAMC, Oklahoma City, OK 73104, USA
Arthritis Rheum 58:2511-7. 2008..The present study was undertaken to investigate the prevalence of Klinefelter's syndrome in a large population of patients with SLE... - Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response indexMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1784-8. 2008..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index... - Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal responseMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1789-95. 2008..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis... - Lymphoma in a patient with systemic lupus erythematosusSasha Bernatsky
, Montreal, , Canada
Nat Clin Pract Rheumatol 2:570-4; quiz 575. 2006..MANAGEMENT: The patient promptly underwent chemotherapy, receiving three courses of 3 mg/m(2) vindesine on day 1, 1,500 mg/m(2) cyclophosphamide and 80 mg/m(2) doxorubicin on day 2, and 50 mg/m(2) prednisolone on days 1-5... - Genetic variation in the CRP promoter: association with systemic lupus erythematosusJeffrey C Edberg
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
Hum Mol Genet 17:1147-55. 2008..These data demonstrate that rs3093061 at the -707 site within the CRP gene is an SLE susceptibility locus... - Malignancies and cyclophosphamide exposure in Wegener's granulomatosisSasha Bernatsky
J Rheumatol 35:11-3. 2008 - Exploring the links between systemic lupus erythematosus and cancerSasha Bernatsky
Division of Clinical Epidemiology, Montreal General Hospital, Montreal, QC H3G 1A4, Canada
Rheum Dis Clin North Am 31:387-402, viii-ix. 2005..This should provide much-needed insight into the pathogenesis of the association between cancer and SLE... - Malignancy and autoimmunitySasha Bernatsky
Division of Clinical Epidemiology, Montreal General Hospital, Quebec, Canada
Curr Opin Rheumatol 18:129-34. 2006..This review focuses on recent publications regarding risk of cancer in these conditions...
Research Grants
- Exposure to Immunosuppressive Drugs & Cancer Risk in SLERosalind Ramsey Goldman; Fiscal Year: 2005..If certain ISDs are linked to cancer risk, prescribing patterns may change. This study may also provide new information about potential links between cancer and autoimmunity. ..
- Patient Oriented Research: Systemic Lupus ErythematosusRosalind Ramsey Goldman; Fiscal Year: 2007..abstract_text> ..