Alfred W Rademaker

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Quantification of cervical spine muscle fat: a comparison between T1-weighted and multi-echo gradient echo imaging using a variable projection algorithm (VARPRO)
    James M Elliott
    Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 North Michigan Avenue, Suite 1100 room 1139, Chicago, IL 60611, USA
    BMC Med Imaging 13:30. 2013
  2. pmc Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis
    Xianpeng Liu
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University, Chicago, IL 60611, USA
    BMC Cancer 14:57. 2014
  3. ncbi request reprint Eating ability in head and neck cancer patients after treatment with chemoradiation: a 12-month follow-up study accounting for dropout
    Alfred W Rademaker
    Robert H Lurie Comprehensive Cancer Center, Northwestern University, Suite 1102, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Head Neck 25:1034-41. 2003
  4. ncbi request reprint Effects of radiotherapy with or without chemotherapy on tongue strength and swallowing in patients with oral cancer
    Cathy Lazarus
    Voice, Speech and Language Service and Swallowing Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Head Neck 29:632-7. 2007
  5. pmc Swallowing disorders in the first year after radiation and chemoradiation
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA
    Head Neck 30:148-58. 2008
  6. ncbi request reprint Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208 3540, USA
    Head Neck 28:1069-76. 2006
  7. pmc Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA
    Head Neck 33:774-9. 2011
  8. pmc Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208 3540, USA
    Dysphagia 24:196-203. 2009
  9. doi request reprint FIGO stage IIIC endometrial carcinoma: prognostic factors and outcomes
    Anna V Hoekstra
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Gynecol Oncol 114:273-8. 2009
  10. pmc Effects of enhanced bolus flavors on oropharyngeal swallow in patients treated for head and neck cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208 3540, USA
    Head Neck 35:1124-31. 2013

Detail Information

Publications93

  1. pmc Quantification of cervical spine muscle fat: a comparison between T1-weighted and multi-echo gradient echo imaging using a variable projection algorithm (VARPRO)
    James M Elliott
    Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 North Michigan Avenue, Suite 1100 room 1139, Chicago, IL 60611, USA
    BMC Med Imaging 13:30. 2013
    ....
  2. pmc Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis
    Xianpeng Liu
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University, Chicago, IL 60611, USA
    BMC Cancer 14:57. 2014
    ..Here we demonstrate that Smurf2 expression is downregulated in human breast cancer tissues, especially of the triple-negative subtype, and address the mechanism of Smurf2 downregulation in triple-negative breast cancer cells...
  3. ncbi request reprint Eating ability in head and neck cancer patients after treatment with chemoradiation: a 12-month follow-up study accounting for dropout
    Alfred W Rademaker
    Robert H Lurie Comprehensive Cancer Center, Northwestern University, Suite 1102, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Head Neck 25:1034-41. 2003
    ..This study was designed to characterize eating ability over 12 months after chemoradiation treatment. Analyses take patient dropout into account...
  4. ncbi request reprint Effects of radiotherapy with or without chemotherapy on tongue strength and swallowing in patients with oral cancer
    Cathy Lazarus
    Voice, Speech and Language Service and Swallowing Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Head Neck 29:632-7. 2007
    ..Oral tongue strength and swallowing ability are reduced in patients treated with chemoradiotherapy for oral and oropharyngeal cancer...
  5. pmc Swallowing disorders in the first year after radiation and chemoradiation
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA
    Head Neck 30:148-58. 2008
    ..Radiation alone or concurrent chemoradiation can result in severe swallowing disorders. This manuscript defines the swallowing disorders occurring at pretreatment and 3 and 12 months after completion of radiation or chemoradiation...
  6. ncbi request reprint Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208 3540, USA
    Head Neck 28:1069-76. 2006
    ..Few studies, however, have related observed swallowing disorders with the patient's oral intake and diet in a large cohort of patients...
  7. pmc Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA
    Head Neck 33:774-9. 2011
    ..Acute oral mucositis is associated with pain and impaired swallowing. Little information is available on the effects of chronic mucositis on swallowing...
  8. pmc Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208 3540, USA
    Dysphagia 24:196-203. 2009
    ....
  9. doi request reprint FIGO stage IIIC endometrial carcinoma: prognostic factors and outcomes
    Anna V Hoekstra
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Gynecol Oncol 114:273-8. 2009
    ..Investigate the clinicopathologic characteristics, nodal distribution, and postoperative treatment of patients with FIGO stage IIIC endometrial carcinoma and determine patterns of recurrence and survival...
  10. pmc Effects of enhanced bolus flavors on oropharyngeal swallow in patients treated for head and neck cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208 3540, USA
    Head Neck 35:1124-31. 2013
    ..Treatment for head and neck cancer can reduce peripheral sensory input and impair oropharyngeal swallow. This study examined the effect of enhanced bolus flavor on liquid swallows in these patients...
  11. pmc Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA
    Head Neck 28:64-73. 2006
    ..The relationship between type of chemoradiation treatment, site of disease, and swallowing function has not been sufficiently examined in patients with head and neck cancer treated primarily with chemoradiation...
  12. pmc Navigating veterans with an abnormal prostate cancer screening test: a quasi-experimental study
    Melissa A Simon
    Robert H, Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
    BMC Health Serv Res 13:314. 2013
    ..This study evaluates the impact of a patient navigation intervention on timeliness of diagnostic resolution and treatment initiation among veterans with an abnormal prostate cancer screen...
  13. doi request reprint F-18 FDG-PET predicts outcomes for patients receiving total lymphoid irradiation and autologous blood stem-cell transplantation for relapsed and refractory Hodgkin lymphoma
    Ryan D Gentzler
    Division of Hematology Oncology and the Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Br J Haematol 165:793-800. 2014
    ..Achievement of CR with salvage therapy is a powerful predictor of outcome. ..
  14. doi request reprint Association between type of reconstruction after Mohs micrographic surgery and surgeon-, patient-, and tumor-specific features: a cross-sectional study
    Murad Alam
    Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Dermatol Surg 39:51-5. 2013
    ..There are few data to indicate whether the type of final wound defect is associated with the type of post-Mohs repair...
  15. ncbi request reprint Xerostomia: 12-month changes in saliva production and its relationship to perception and performance of swallow function, oral intake, and diet after chemoradiation
    Jeri A Logemann
    Northwestern University, Department of Communication Sciences and Disorders, 2299 N Campus Drive, Evanston, Illinois 60208, USA
    Head Neck 25:432-7. 2003
    ..Previous investigators have found permanent changes in saliva production after chemoradiation but have not examined these in relation to swallowing measures, diet changes, and patient comfort over time...
  16. pmc Yttrium-90 ibritumomab tiuxetan doses calculated to deliver up to 15 Gy to critical organs may be safely combined with high-dose BEAM and autologous transplantation in relapsed or refractory B-cell non-Hodgkin's lymphoma
    Jane N Winter
    Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Clin Oncol 27:1653-9. 2009
    ....
  17. ncbi request reprint Tamoxifen use in patients with ductal carcinoma in situ and T1a/b N0 invasive carcinoma
    Faina Nakhlis
    Department of Surgery, Lynn Sage Breast Program, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Am Coll Surg 201:688-94. 2005
    ..The purpose of this study was to determine how often patients with ductal carcinoma in situ and T1a/b N0 cancer are offered and accept tamoxifen for secondary chemoprevention...
  18. ncbi request reprint Swallow function and perception of dysphagia in patients with head and neck cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2299 N Campus Drive, Evanston, Illinois 60208 3540, USA
    Head Neck 24:555-65. 2002
    ....
  19. doi request reprint The utility of dermoscopy-guided histologic sectioning for the diagnosis of melanocytic lesions: A case-control study
    Emily A Merkel
    Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
    J Am Acad Dermatol 74:1107-13. 2016
    ..However, dermoscopic features are rarely considered during routine histologic sectioning, and areas of clinical concern may be missed during microscopic evaluation...
  20. pmc Brachial plexus dose tolerance in head and neck cancer patients treated with sequential intensity modulated radiation therapy
    Tarita O Thomas
    Department of Radiation Oncology, Northwestern University, Robert H Lurie Comprehensive Cancer Center, 251 East Huron, LC 178, Chicago, IL, 60611, USA
    Radiat Oncol 10:94. 2015
    ..We aimed to study the radiation induced brachial plexopathy in patients with head and neck squamous cell carcinoma (HNSCC) treated with Sequential Intensity Modulated Radiation Therapy (S-IMRT)...
  21. pmc Comparing the Performance of the S-TOFHLA and NVS Among and Between English and Spanish Speakers
    Vanessa Ramirez-Zohfeld
    a Division of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Health Commun 20:1458-64. 2015
    ....
  22. doi request reprint Outcome of patients treated with a single-fraction dose of palliative radiation for cutaneous T-cell lymphoma
    Tarita O Thomas
    Department of Radiation Oncology, Northwestern University, Robert H Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
    Int J Radiat Oncol Biol Phys 85:747-53. 2013
    ..The current literature lacks data that support single-fraction treatment for CTCL. This retrospective review assesses the clinical response in patients treated with a single fraction of radiation...
  23. doi request reprint Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: factors associated with resistance to single-agent methotrexate chemotherapy
    Eloise Chapman-Davis
    Department of Obstetrics and Gynecology, John I Brewer Trophoblastic Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Gynecol Oncol 125:572-5. 2012
    ..To determine factors associated with resistance to methotrexate treatment of low-risk gestational trophoblastic neoplasia (GTN)...
  24. ncbi request reprint Scintigraphic response by 123I-metaiodobenzylguanidine scan correlates with event-free survival in high-risk neuroblastoma
    Howard M Katzenstein
    Division of Hematology Oncology, Department of Pediatrics, Northwestern University, Children s Memorial Hospital, 2300 Children s Plaza, Box 30, Chicago, IL 60614, USA
    J Clin Oncol 22:3909-15. 2004
    ..To investigate whether response to induction therapy, evaluated by metaiodobenzylguanadine (MIBG) and bone scintigraphy, correlates with event-free survival (EFS) in children with high-risk neuroblastoma (NB)...
  25. ncbi request reprint Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer
    Barbara Roa Pauloski
    Communication Sciences and Disorders, Northwestern University, 2240 N Campus Drive, Evanston, IL 60208 3540, USA
    Head Neck 26:625-36. 2004
    ..Postoperative swallowing function may be influenced by a number of treatment variables; this study examines the relationship of various treatment factors to measures of swallow function...
  26. ncbi request reprint Effects of voluntary maneuvers on tongue base function for swallowing
    Cathy Lazarus
    Veterans Administration Lakeside Medical Center, Northwestern University Medical School, Chicago, Ill, USA
    Folia Phoniatr Logop 54:171-6. 2002
    ..Preliminary data are provided to support the use of swallow maneuvers to improve tongue base posterior motion and pressures generated at the tongue base-pharyngeal wall level during swallowing in patients who exhibit this disorder...
  27. doi request reprint Mitoxantrone and etoposide with or without intermediate dose cytarabine for the treatment of primary induction failure or relapsed acute myeloid leukemia
    Steven M Trifilio
    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL 60611, USA
    Leuk Res 36:394-6. 2012
    ..Differences in CR between ME and MEC subsets were analyzed to determine the effect of cytarabine to ME...
  28. pmc Effect of induction chemotherapy on swallow physiology and saliva production in patients with head and neck cancer: a pilot study
    Bharat B Mittal
    Department of Radiation Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    Head Neck 37:567-72. 2015
    ..No objective data are available to assess the potential damage induction chemotherapy alone contributes to swallowing physiology and salivary production in patients with locally and regionally confined head and neck cancer...
  29. doi request reprint A comprehensive quality assurance program for personnel and procedures in radiation oncology: value of voluntary error reporting and checklists
    John A Kalapurakal
    Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Int J Radiat Oncol Biol Phys 86:241-8. 2013
    ..This report describes the value of a voluntary error reporting system and the impact of a series of quality assurance (QA) measures including checklists and timeouts on reported error rates in patients receiving radiation therapy...
  30. doi request reprint Communication failure in the operating room
    Amy L Halverson
    Department of Surgery, Feinberg School of Medicine and Northwestern Memorial Hospital, Northwestern University, Chicago, IL 60611, USA
    Surgery 149:305-10. 2011
    ..Our aim was to characterize the nature of communication failures observed in the operating room and to assess whether a Team Training curriculum had any impact on observed communication errors...
  31. doi request reprint Delayed treatment and continued growth of nonmelanoma skin cancer
    Murad Alam
    Section of Cutaneous and Aesthetic Surgery, Department of Dermatology, Northwestern University, Chicago, Illinois 60611, USA
    J Am Acad Dermatol 64:839-48. 2011
    ..Patients may delay treatment for skin cancer for various reasons. Prior research on treatment delay has focused on melanoma rather than nonmelanoma skin cancer (NMSC), which is much more common...
  32. pmc The role of activin A and Akt/GSK signaling in ovarian tumor biology
    Thuy Vy Do
    Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60611 3008, USA
    Endocrinology 149:3809-16. 2008
    ..046). Our data are consistent with a model in which activin A may mediate ovarian oncogenesis by activating Akt and repressing GSK to stimulate cellular proliferation...
  33. doi request reprint Effectiveness of a knowledge-based intervention for melanoma among those with ethnic skin
    Roopal V Kundu
    Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Am Acad Dermatol 62:777-84. 2010
    ..Among patients with melanoma, ethnic minorities are 1.96 to 3.01 times as likely to die from melanoma as Caucasians of the same age and sex...
  34. ncbi request reprint Factors influencing outcomes for breast conservation therapy of mammographically detected malignancies
    Valerie L Staradub
    Lynn Sage Breast Center, Department of Surgery, Division of Surgical Oncology, Northwestern University Medical School, 201 E Huron Street, Galter 10 105, Chicago, IL 60611, USA
    J Am Coll Surg 196:518-24. 2003
    ..To evaluate the importance of surgeon caseload, lesion type, and biopsy type on outcomes in breast conservation therapy (BCT)...
  35. ncbi request reprint Effects of two types of tongue strengthening exercises in young normals
    Cathy Lazarus
    Voice, Speech and Language Service and Swallowing Center, Northwestern University Medical School, Chicago, Ill, USA
    Folia Phoniatr Logop 55:199-205. 2003
    ..04). Results provide support for the theory that tongue strengthening exercises improve tongue strength in healthy young subjects...
  36. pmc Behavioral intervention to promote smoking cessation and prevent weight gain: a systematic review and meta-analysis
    Bonnie Spring
    Department of PreventiveMedicine, Northwestern University, 680 N Lakeshore Drive, Suite 1220, Chicago, IL 60611, USA
    Addiction 104:1472-86. 2009
    ..We reviewed evidence to determine whether behavioral weight control intervention compromises smoking cessation attempts, and if it offers an effective way to reduce post-cessation weight gain...
  37. doi request reprint Meta-analysis of the efficacy and safety of alpha2-adrenergic agonists, beta-adrenergic antagonists, and topical carbonic anhydrase inhibitors with prostaglandin analogs
    Angelo P Tanna
    Department of Ophthalmology, Northwestern University Feinberg School of Medicine, 645 N Michigan Ave, Chicago, IL 60611, USA
    Arch Ophthalmol 128:825-33. 2010
    ....
  38. ncbi request reprint Aesthetic and functional efficacy of subcuticular running epidermal closures of the trunk and extremity: a rater-blinded randomized control trial
    Murad Alam
    Section of Cutaneous and Aesthetic Surgery, Department of Dermatology, Northwestern University, Chicago, IL, USA
    Arch Dermatol 142:1272-8. 2006
    ..To ascertain whether subcuticular epidermal closures of elliptical excisions of the trunk and extremities result in better functional and cosmetic outcomes than simple running epidermal closures of the same sites...
  39. ncbi request reprint Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis
    Eileen H Bigio
    Northwestern Cognitive Neurology and Alzheimer Disease Center, and Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Neuropathol Exp Neurol 63:801-11. 2004
    ..In addition, the current study confirms that Ub-INIs are found in familial FTD-MND-type, but also extends the presence of Ub-INIs to familial FTD-MND (with concomitant ALS), and probably also to non-familial FTD-MND-type...
  40. ncbi request reprint Health care provider-directed intervention to increase colorectal cancer screening among veterans: results of a randomized controlled trial
    M Rosario Ferreira
    Veterans Affairs Midwest Center for Health Services and Policy Research, Hines, USA
    J Clin Oncol 23:1548-54. 2005
    ..Colorectal cancer screening is the most underused cancer screening tool in the United States. The purpose of this study was to test whether a health care provider-directed intervention increased colorectal cancer screening rates...
  41. pmc Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
    Melissa L Johnson
    Melissa L Johnson, Jyoti D Patel, Eric M Hart, Bing Bing Weitner, and Alfred W Rademaker, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL and Helena A Yu, Mark G Kris, and Gregory J Riely, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY
    J Clin Oncol 33:1666-73. 2015
    ..We conducted a phase I/II trial to evaluate AUY922 and erlotinib for patients with EGFR-mutant lung cancer and disease progression during erlotinib treatment...
  42. pmc Maternal leptin predicts adiposity of the neonate
    Jami L Josefson
    Division of Endocrinology, Ann and Robert H Lurie Children s Hospital of Chicago, Chicago, Ill, USA
    Horm Res Paediatr 81:13-9. 2014
    ..Maternal obesity and hyperglycemia in pregnancy are associated with increased neonatal adiposity; however, features of maternal obesity that contribute to increased neonatal adiposity need further study...
  43. pmc Expression of estrogen-related gene markers in breast cancer tissue predicts aromatase inhibitor responsiveness
    Irene Moy
    Northwestern University, Department of Obstetrics and Gynecology, Chicago, Illinois, United States of America
    PLoS ONE 8:e77543. 2013
    ..In conclusion, expression levels of estrogen-related mRNAs are predictive for AI responsiveness in postmenopausal women with breast cancer, and mRNA expression analysis may improve patient selection. ..
  44. pmc Exercise effects on depressive symptoms in cancer survivors: a systematic review and meta-analysis
    Lynette L Craft
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Suite 1400, Chicago, IL 60611, USA
    Cancer Epidemiol Biomarkers Prev 21:3-19. 2012
    ..Depression is a distressing side effect of cancer and its treatment. In the general population, exercise is an effective antidepressant...
  45. doi request reprint Association between number of stages in Mohs micrographic surgery and surgeon-, patient-, and tumor-specific features: a cross-sectional study of practice patterns of 20 early- and mid-career Mohs surgeons
    Murad Alam
    Department of Dermatology, Otolaryngology, and Surgery, Northwestern University, Chicago, IL, USA
    Dermatol Surg 36:1915-20. 2010
    ..To determine the number of Mohs micrographic surgery (MMS) stages per tumor taken by early- to mid-career Mohs surgeons and to assess other factors affecting number of stages...
  46. doi request reprint A phase 2 trial of single-agent bevacizumab given in an every-3-week schedule for patients with recurrent high-grade gliomas
    Jeffrey J Raizer
    Department of Neurology, Northwestern University, Chicago, IL, USA
    Cancer 116:5297-305. 2010
    ..The authors evaluated a 3-week schedule of bevacizumab in patients with recurrent high-grade glioma (HGG)...
  47. ncbi request reprint Characteristics of salivary profiles of oestradiol and progesterone in premenopausal women
    Robert T Chatterton
    Department of Obstetrics Gynaecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Endocrinol 186:77-84. 2005
    ..In addition, it emphasizes the importance of sampling at multiple time points when examining the relationship between hormones and risk...
  48. ncbi request reprint Increased microvascular density predicts relapse in Wilms' tumor
    Lisa P Abramson
    Division of Pediatric Surgery, Children s Memorial Hospital, Department of Biostatistics, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Pediatr Surg 38:325-30; discussion 325-30. 2003
    ..The authors postulated that increased microvascular density (MVD), a hallmark for angiogenesis, could identify patients at risk for relapse...
  49. doi request reprint Gestational trophoblastic neoplasia: treatment outcomes
    Anna V Hoekstra
    John I Brewer Trophoblastic Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Obstet Gynecol 112:251-8. 2008
    ..Brewer Trophoblastic Disease Center over the past 28 years, compare the outcomes to those from the first 16 years, and analyze factors affecting response to treatment and survival...
  50. ncbi request reprint Implications of therapy choice on overall survival in metastatic renal cell carcinoma: a single institution experience
    Simrit Parmar
    Department of Medicine, Division of Hematology Oncology, Northwestern University Feinberg School of Medicine and the Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
    Med Oncol 22:399-405. 2005
    ..To compare the effect of high-dose interleukin-2 (HD IL-2) vs other cytokine therapies on 1-, 2, and 5-yr overall survival in patients with metastatic renal cell cancer (RCC)...
  51. doi request reprint Comparison of sentinel lymph node biopsy alone and completion axillary lymph node dissection for node-positive breast cancer
    Karl Y Bilimoria
    Cancer Programs, American College of Surgeons, Chicago, IL 60611, USA
    J Clin Oncol 27:2946-53. 2009
    ..Our objectives were to assess national nodal evaluation practice patterns and to examine differences in recurrence and survival for SLNB alone versus SLNB with completion ALND...
  52. ncbi request reprint The effects of taste and consistency on swallow physiology in younger and older healthy individuals: a surface electromyographic study
    Ruiying Ding
    Northwestern University, Evanston, IL, USA
    J Speech Lang Hear Res 46:977-89. 2003
    ..Interaction of taste, consistency, and age was also noted for onset time at the submental and infrahyoid sites...
  53. doi request reprint Melanoma Perception in People of Color: A Targeted Educational Intervention
    Lucy X Chao
    Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Ste 1600, Chicago, IL, 60611, USA
    Am J Clin Dermatol . 2016
    ..Although melanoma is more common in non-Hispanic Whites, ethnic minorities face a greater risk of melanoma-related mortality, which may be partially attributed to presentation at atypical sites and a lack of awareness...
  54. pmc The Effectiveness of a Physician-Only and Physician-Patient Intervention on Colorectal Cancer Screening Discussions Between Providers and African American and Latino Patients
    Nancy C Dolan
    Division of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, 675 N St Clair St Suite 18 200, Chicago, IL, 60611, USA
    J Gen Intern Med 30:1780-7. 2015
    ..Providing patients a choice of screening options may increase CRC screening completion, particularly among racial and ethnic minorities...
  55. pmc Circadian melatonin rhythm and excessive daytime sleepiness in Parkinson disease
    Aleksandar Videnovic
    Neurological Clinical Research Institute, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts2Department of Neurology, Northwestern University, Chicago, Illinois
    JAMA Neurol 71:463-9. 2014
    ..However, surprisingly little is known regarding circadian function in PD and whether circadian dysfunction is involved in the development of sleep-wake disturbances in PD...
  56. doi request reprint An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era
    Zheng Zhou
    Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL
    Blood 123:837-42. 2014
    ..The NCCN-IPI is easy to apply and more powerful than the IPI for predicting survival in the rituximab era. ..
  57. ncbi request reprint Factors that influence surgical choices in women with breast carcinoma
    Valerie L Staradub
    Division of Surgical Oncology, Department of Surgery, Northwestern University Medical School, Chicago, Illinois, USA
    Cancer 95:1185-90. 2002
    ..The authors studied demographic factors to identify the variables that differed significantly among women making different surgical choices...
  58. pmc Design of a prostate cancer patient navigation intervention for a Veterans Affairs hospital
    Narissa J Nonzee
    Robert H, Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA
    BMC Health Serv Res 12:340. 2012
    ....
  59. pmc High aromatase expression in uterine leiomyoma tissues of African-American women
    Hiroshi Ishikawa
    Division of Reproductive Biology Research, Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
    J Clin Endocrinol Metab 94:1752-6. 2009
    ..African-American women develop uterine leiomyomas at an earlier age and with higher frequency compared with Caucasian-American women or other races; however, the underlying mechanism for this discrepancy is unknown...
  60. ncbi request reprint Phenethyl isothiocyanate inhibits nitrosamine carcinogenesis in a model for study of oral cancer chemoprevention
    Dennis B Solt
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Cancer Lett 202:147-52. 2003
    ..PEITC also reduced tumor formation by 94%. gamma-GT, in particular, may be a useful indicator for identification of effective oral cancer chemopreventive agents and combinations of agents...
  61. doi request reprint Psychological impact of recall in high-risk breast MRI screening
    Suzanne M O'Neill
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Breast Cancer Res Treat 115:365-71. 2009
    ..To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects...
  62. ncbi request reprint Phase I trial of oral estramustine and 3-hr infusional paclitaxel for the treatment of hormone refractory prostate cancer
    Timothy M Kuzel
    Division of Hematology Oncology, Department of Medicine, Robert H Lurie Comprehensive Cancer Center of Northwestern University Medical School, 676 N St Clair, Suite 850, Chicago, IL 60611, USA
    Cancer Invest 20:634-43. 2002
    ..Significant anti-tumor activity has been reconfirmed despite the change in schedule of administration of the paclitaxel...
  63. doi request reprint Toxicity profile of approved anti-PD-1 monoclonal antibodies in solid tumors: a systematic review and meta-analysis of randomized clinical trials
    Ricardo Costa
    Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Oncotarget . 2016
    ..This meta-analysis of randomized clinical trials aims to summarize current knowledge regarding the toxicity profile of these agents...
  64. doi request reprint The changing landscape of phase II/III metastatic NSCLC clinical trials and the importance of biomarker selection criteria
    Ryan D Gentzler
    Division of Hematology Oncology, Feinberg School of Medicine, Northwestern University, Robert H Lurie Comprehensive Cancer Center, Chicago, Illinois
    Cancer 120:3853-8. 2014
    ..These changes are likely attributed to the use of histology and biomarker selection criteria in clinical trial design...
  65. pmc The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy
    Lijie Zhai
    Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Tarry Bldg 2 703, 300 East Superior Street, Chicago, IL 60611, USA
    J Clin Neurosci 22:1964-8. 2015
    ....
  66. pmc Development of a standardized method for contouring the larynx and its substructures
    Mehee Choi
    Department of Radiation Oncology, Northwestern University, Robert H Lurie Comprehensive Cancer Center, 251 E Huron, LC 178, Chicago, IL, 60611, USA
    Radiat Oncol 9:285. 2014
    ..This study presents computed tomography (CT)- and magnetic resonance imaging (MRI)-based guidelines for contouring laryngeal organs-at-risk (OARs)...
  67. ncbi request reprint Clearance of nasal Staphylococcus aureus colonization with triple antibiotic ointment
    Elizabeth M Grossman
    Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Drugs Dermatol 11:1490-2. 2012
    ..Staphyloccocal resistance to mupirocin has been described, requiring additional management strategies. In certain situations, triple antibiotic ointment (TAO) may be a suitable alternative for elimination of nasal S aureus colonization...
  68. pmc Maternal obesity and vitamin D sufficiency are associated with cord blood vitamin D insufficiency
    Jami L Josefson
    Division of Pediatric Endocrinology, Ann and Robert H Lurie Children s Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 2605, USA
    J Clin Endocrinol Metab 98:114-9. 2013
    ..However, the relationship between neonatal adiposity and vitamin D status has not been reported. Both maternal obesity and vitamin D deficiency in pregnancy are common and are associated with adverse pregnancy outcomes...
  69. ncbi request reprint In vivo generation of angiostatin isoforms by administration of a plasminogen activator and a free sulfhydryl donor: a phase I study of an angiostatic cocktail of tissue plasminogen activator and mesna
    Gerald A Soff
    Division of Hematology Oncology, Department of Medicine, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    Clin Cancer Res 11:6218-25. 2005
    ..A free sulfhydryl donor can mediate plasmin autoproteolysis. To translate this process to human cancer therapy, we conducted a phase I trial of administration of a tissue plasminogen activator (tPA) with a free sulfhydryl donor (mesna)...
  70. ncbi request reprint Peripheral excision margins for dermatofibrosarcoma protuberans: a meta-analysis of spatial data
    Zebadiah Kimmel
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Ann Surg Oncol 14:2113-20. 2007
    ..The purpose of this study was to analyze available datasets to assess the degree of asymmetry typically associated with DFSP, and to study the optimal surgical approach for extirpating these tumors by clearing lateral margins...
  71. ncbi request reprint Treatment of high-risk neuroblastoma with triple-tandem high-dose therapy and stem-cell rescue: results of the Chicago Pilot II Study
    Morris Kletzel
    Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    J Clin Oncol 20:2284-92. 2002
    ....
  72. ncbi request reprint A phase I study of docetaxel, Cisplatin, 5-Fluorouracil and leucovorin
    Mary F Mulcahy
    Division of Hematology Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Oncology 68:479-84. 2005
    ..This phase I study was undertaken to determine the maximally tolerated dose and dose-limiting toxicities of a combination of these drugs given in an ambulatory setting using a bolus schedule of 5-FU...
  73. doi request reprint Comparison of electrodesiccation and potassium-titanyl-phosphate laser for treatment of dermatosis papulosa nigra
    Roopal V Kundu
    Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Dermatol Surg 35:1079-83. 2009
    ..There is a lack of randomized split-face studies investigating treatments for dermatosis papulosa nigra (DPN) in dark skin...
  74. ncbi request reprint Colorectal cancer screening among African-American and white male veterans
    Nancy C Dolan
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Prev Med 28:479-82. 2005
    ..The purpose of this study was to evaluate whether, at a Veterans Affairs (VA) medical center, similar racial/ethnic differences in colorectal cancer screening could be identified...
  75. ncbi request reprint Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer
    Jacqueline S Jeruss
    Department of Neurobiology and Physiology and Robert H Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois 60208, USA
    Cancer Res 63:3783-90. 2003
    ..Thus, activin signal transduction components are present in normal tissue and grade 1 cancer but down-regulated in high-grade cancer. The deregulation of this signal transduction system may be relevant to advancing oncogenic progression...
  76. ncbi request reprint Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience
    Punit Chadha
    Division of Hematology Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Suite 700, Chicago, IL 60611, USA
    Blood 106:241-6. 2005
    ..There were 15 patients (17%) who developed other malignancies. Long-term follow-up of up to 14 years (median: 9.7 years) showed an excellent PFS and OS for HCL patients after 2-CdA treatment...
  77. doi request reprint Surgical team training: the Northwestern Memorial Hospital experience
    Amy L Halverson
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Arch Surg 144:107-12. 2009
    ..To develop and implement a team-training curriculum. We hypothesized that better interactions between personnel would lead to improved patient safety, increased efficiency, and better staff satisfaction...
  78. ncbi request reprint Oropharyngeal swallow in younger and older women: videofluoroscopic analysis
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    J Speech Lang Hear Res 45:434-45. 2002
    ..Older women also exhibited an increased range of motion relative to the old men. This increase may indicate a compensation for aging effects not seen in older men...
  79. ncbi request reprint Surface electromyographic and electroglottographic studies in normal subjects under two swallow conditions: normal and during the Mendelsohn manuever
    Ruiying Ding
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208 3540, USA
    Dysphagia 17:1-12. 2002
    ..The sequence of the most frequent muscle termination was orbicularis oris superior, orbicularis oris inferior, masseter, submental muscle group, and infrahyoid muscle group in both normal swallow and the Mendelsohn maneuver...
  80. ncbi request reprint Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice
    Ruth M O'Regan
    Division of Hematology Oncology, Northwestern University, Chicago, IL 60611, USA
    J Natl Cancer Inst 94:274-83. 2002
    ..We evaluated the effects on tumor growth of raloxifene, another SERM, after tamoxifen treatment in mouse models of breast and endometrial cancers...
  81. ncbi request reprint Predictive formula for calculating the probability of LASIK enhancement
    Daniel J Hu
    Northwestern Laser Vision Center, Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    J Cataract Refract Surg 30:363-8. 2004
    ..To develop a formula to predict a patient's need for laser in situ keratomileusis (LASIK) enhancement...
  82. ncbi request reprint Localization of the activin signal transduction components in normal human ovarian follicles: implications for autocrine and paracrine signaling in the ovary
    Stephanie A Pangas
    Department of Neurobiology and Physiology, Northwestern University, 2153 North Campus Drive, Evanston, IL 60208, USA
    J Clin Endocrinol Metab 87:2644-57. 2002
    ..Together, these data strongly suggest that the intraovarian role of activin is limited to a few developmental stages and that other TGF-beta family members may use this cell autonomous signaling machinery in early follicle development...
  83. ncbi request reprint Swallowing and speech ability after treatment for head and neck cancer with targeted intraarterial versus intravenous chemoradiation
    Lisa A Newman
    University of Tennessee College of Medicine, Memphis, Tennessee, USA
    Head Neck 24:68-77. 2002
    ..This study was designed to quantify and compare RADPLAT and systemic chemoradiation treatment effects on swallowing and speech...
  84. ncbi request reprint Multicenter randomized Phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer
    Fred R Rosen
    Department of Medicine, Section of Hematology Oncology, University of Illinois at Chicago, 60637, USA
    Clin Cancer Res 9:1689-97. 2003
    ....
  85. ncbi request reprint Weekly carboplatin and paclitaxel followed by concomitant paclitaxel, fluorouracil, and hydroxyurea chemoradiotherapy: curative and organ-preserving therapy for advanced head and neck cancer
    Everett E Vokes
    Department of Medicine, Section of Hematology Oncology, University of Chicago IL 60637 1470, USA
    J Clin Oncol 21:320-6. 2003
    ..Locoregional and distant failure rates were 13% and 23%, respectively. To reduce distant failure rates, we added a brief course of induction chemotherapy to TFHX...
  86. ncbi request reprint Process evaluation in an intervention designed to improve rates of colorectal cancer screening in a VA medical center
    Marian L Fitzgibbon
    University of Illinois at Chicago, Section of Health Promotion Research, Department of Medicine, IL 60608, USA
    Health Promot Pract 8:273-81. 2007
    ..05). The patient intervention did not have the desired impact. The subgroup of patients in the patient intervention was not more likely to complete CRC screening...
  87. ncbi request reprint Oral and oropharyngeal perceptions of fluid viscosity across the age span
    Christina H Smith
    Department of Human Communication Science, University College London, London, England
    Dysphagia 21:209-17. 2006
    ..Men exhibited a more marked deterioration in sensitivity than women. This study contributes to the literature on oral and oropharyngeal perceptions and on aging. The results provide a basis for work with individuals with dysphagia...
  88. ncbi request reprint Weekly topotecan for recurrent platinum resistant ovarian cancer
    Fadi Abushahin
    The Cleveland Clinic, Cleveland, OH, USA
    Gynecol Oncol 108:53-7. 2008
    ..To evaluate toxicity, response and progression-free survival of weekly topotecan chemotherapy in women with primary and secondary platinum-resistant epithelial ovarian cancer...
  89. ncbi request reprint Analysis of aneuploidy in spermatozoa from testicular biopsies from men with nonobstructive azoospermia
    Renee H Martin
    Department of Medical Genetics, Faculty of Medicine, Alberta Children s Hospital, University of Calgary, Alberta, Canada
    J Androl 24:100-3. 2003
    ....
  90. ncbi request reprint Altered kallikrein 7 and 10 concentrations in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia
    Eleftherios P Diamandis
    Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada
    Clin Biochem 37:230-7. 2004
    ..Some of these enzymes can be measured in cerebrospinal fluid (CSF) by using ELISA-type methodologies...
  91. ncbi request reprint Oropharyngeal deglutition in stable COPD
    Babak Mokhlesi
    Division of Pulmonary and Critical Care, Northwestern University Medical School and the Veterans Administration Chicago Healthcare System Lakeside Division, IL, USA
    Chest 121:361-9. 2002
    ..The aim of this study was to examine deglutition in stable patients with COPD and lung hyperinflation...
  92. ncbi request reprint Beyond efficacy and effectiveness: conducting economic analyses during clinical trials
    Teresa M Waters
    Center for Health Services Research, The University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Dysphagia 19:109-19. 2004
    ..S. population. Attrition from the overall study population can pose a serious threat to the viability of an economic study. The article concludes with a discussion of how these issues can be addressed in future studies...
  93. ncbi request reprint The prognostic significance of Gail model risk factors for women with breast cancer
    Paul Ian Tartter
    Department of Surgery, St Luke s Roosevelt Hospital Center, New York, NY, USA
    Am J Surg 184:11-5. 2002
    ..In order to assess the prognostic value of risk factors for breast cancer we divided patients with breast cancer into those at high risk and low risk using the Gail model...