Matthew R Parsek

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Mucin-Pseudomonas aeruginosa interactions promote biofilm formation and antibiotic resistance
    Rebecca M Landry
    Department of Chemistry, Northwestern University, Evanston, IL 60208, USA
    Mol Microbiol 59:142-51. 2006
  2. ncbi request reprint Bacterial biofilms: an emerging link to disease pathogenesis
    Matthew R Parsek
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208 3109, USA
    Annu Rev Microbiol 57:677-701. 2003
  3. pmc Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa
    Gail M Teitzel
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA
    J Bacteriol 188:7242-56. 2006
  4. pmc Heavy metal resistance of biofilm and planktonic Pseudomonas aeruginosa
    Gail M Teitzel
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Appl Environ Microbiol 69:2313-20. 2003
  5. pmc Characterization of colony morphology variants isolated from Pseudomonas aeruginosa biofilms
    Mary Jo Kirisits
    University of Iowa, Department of Microbiology, 540E EMRB, Iowa City, IA 52242
    Appl Environ Microbiol 71:4809-21. 2005
  6. ncbi request reprint Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities?
    Mary Jo Kirisits
    Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, Austin, TX 78712, USA
    Cell Microbiol 8:1841-9. 2006
  7. pmc The effect of the chemical, biological, and physical environment on quorum sensing in structured microbial communities
    Alexander R Horswill
    Department of Microbiology, University of Iowa, Iowa, IA 52242, USA
    Anal Bioanal Chem 387:371-80. 2007
  8. ncbi request reprint The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional
    Joshua D Shrout
    Department of Microbiology, University of Iowa, Iowa City, IA, USA
    Mol Microbiol 62:1264-77. 2006
  9. ncbi request reprint The promise and peril of transcriptional profiling in biofilm communities
    Dingding An
    Department of Microbiology, University of Washington, School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195 7242, USA
    Curr Opin Microbiol 10:292-6. 2007
  10. pmc Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms
    Mary Jo Kirisits
    Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, 1 University Station C1786, Austin, TX 78712, USA
    J Bacteriol 189:8357-60. 2007

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Mucin-Pseudomonas aeruginosa interactions promote biofilm formation and antibiotic resistance
    Rebecca M Landry
    Department of Chemistry, Northwestern University, Evanston, IL 60208, USA
    Mol Microbiol 59:142-51. 2006
    ..Together, these experiments suggest that mucin, which may serve as an attachment surface in CF airways, impacts P. aeruginosa biofilm development and function...
  2. ncbi request reprint Bacterial biofilms: an emerging link to disease pathogenesis
    Matthew R Parsek
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208 3109, USA
    Annu Rev Microbiol 57:677-701. 2003
    ..The consequences of pathogens living in environmental biofilms and an analysis of some specific environmental biofilm systems are presented...
  3. pmc Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa
    Gail M Teitzel
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA
    J Bacteriol 188:7242-56. 2006
    ..These studies suggest that two resistance nodulation division efflux systems, a P-type ATPase, and a two-component regulator were particularly important for copper tolerance in P. aeruginosa...
  4. pmc Heavy metal resistance of biofilm and planktonic Pseudomonas aeruginosa
    Gail M Teitzel
    Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Appl Environ Microbiol 69:2313-20. 2003
    ....
  5. pmc Characterization of colony morphology variants isolated from Pseudomonas aeruginosa biofilms
    Mary Jo Kirisits
    University of Iowa, Department of Microbiology, 540E EMRB, Iowa City, IA 52242
    Appl Environ Microbiol 71:4809-21. 2005
    ..These variants displayed many of the same characteristics as the laboratory variants, suggesting a link between laboratory and cystic fibrosis biofilms...
  6. ncbi request reprint Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities?
    Mary Jo Kirisits
    Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, Austin, TX 78712, USA
    Cell Microbiol 8:1841-9. 2006
    ..This review will discuss quorum sensing and biofilm formation and studies that link these two processes...
  7. pmc The effect of the chemical, biological, and physical environment on quorum sensing in structured microbial communities
    Alexander R Horswill
    Department of Microbiology, University of Iowa, Iowa, IA 52242, USA
    Anal Bioanal Chem 387:371-80. 2007
    ..As these studies continue to refine our understanding of these mechanisms, an emerging challenge is to identify if and when the local environment can affect signaling...
  8. ncbi request reprint The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional
    Joshua D Shrout
    Department of Microbiology, University of Iowa, Iowa City, IA, USA
    Mol Microbiol 62:1264-77. 2006
    ..These data led to a model proposing that the prevailing nutritional conditions dictate the contributions of quorum sensing and swarming motility at a key juncture early in biofilm development...
  9. ncbi request reprint The promise and peril of transcriptional profiling in biofilm communities
    Dingding An
    Department of Microbiology, University of Washington, School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195 7242, USA
    Curr Opin Microbiol 10:292-6. 2007
    ..Thus, an emerging challenge is to use transcriptional profiling in combination with techniques that can identify and separate relevant subpopulations within a biofilm...
  10. pmc Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms
    Mary Jo Kirisits
    Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, 1 University Station C1786, Austin, TX 78712, USA
    J Bacteriol 189:8357-60. 2007
    ..The amount of biofilm biomass required for full QS induction of the population increased as the flow rate increased...
  11. pmc Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms
    Timothy D Starner
    Department of Pediatrics, University of Iowa, 2080H Medical Laboratories, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Antimicrob Agents Chemother 52:137-45. 2008
    ..influenzae...
  12. ncbi request reprint Microbiology: bilingual bacteria
    Matthew R Parsek
    Nature 450:805-7. 2007
  13. pmc Analysis of Pseudomonas aeruginosa conditional psl variants reveals roles for the psl polysaccharide in adhesion and maintaining biofilm structure postattachment
    Luyan Ma
    Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Bacteriol 188:8213-21. 2006
    ..aeruginosa. This translated into significant changes in the architecture of the biofilm. We propose that Psl has an important role in P. aeruginosa adhesion, which is critical for initiation and maintenance of the biofilm structure...
  14. pmc Quorum sensing and motility mediate interactions between Pseudomonas aeruginosa and Agrobacterium tumefaciens in biofilm cocultures
    Dingding An
    Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 103:3828-33. 2006
    ..a. and that the outcome of competition and the relative contribution of different factors to competition are strongly influenced by the environment in which they occur...
  15. ncbi request reprint Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound
    Morten Hentzer
    Department of Molecular Microbiology, BioCentrum DTU, Technical University of Denmark, DK 2800 Lyngby, Denmark
    Microbiology 148:87-102. 2002
    ..It does, however, affect the architecture of the biofilm and enhances the process of bacterial detachment, leading to a loss of bacterial biomass from the substratum...
  16. pmc Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression
    Arne Heydorn
    Section of Molecular Microbiology, The Technical University of Denmark, DK 2800 Kgs Lyngby, Denmark
    Appl Environ Microbiol 68:2008-17. 2002
    ..The results are discussed in relation to the current model of P. aeruginosa biofilm development...
  17. ncbi request reprint A component of innate immunity prevents bacterial biofilm development
    Pradeep K Singh
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Nature 417:552-5. 2002
    ..These findings reveal a specific anti-biofilm defence mechanism acting at a critical juncture in biofilm development, the time bacteria stop roaming as individuals and aggregate into durable communities...
  18. ncbi request reprint Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis
    Sang Sun Yoon
    Department of Molecular Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Dev Cell 3:593-603. 2002
    ..Thus, future investigations of CF pathogenesis and therapy should include a better understanding of anaerobic metabolism and biofilm development by P. aeruginosa...
  19. pmc Biofilms 2003: emerging themes and challenges in studies of surface-associated microbial life
    Matthew R Parsek
    The University of Iowa, Department of Microbiology, 540E EMRB, Iowa City, IA 52242 1109, USA
    J Bacteriol 186:4427-40. 2004
  20. pmc Identification of psl, a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation
    Kara D Jackson
    Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1064, USA
    J Bacteriol 186:4466-75. 2004
    ..Understanding psl-encoded exopolysaccharide expression and protection in biofilms will provide insight into the pathogenesis of P. aeruginosa in cystic fibrosis and other infections involving biofilms...
  21. pmc Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system
    Thomas Danhorn
    Department of Biology, 1001 E 3rd St, Jordan Hall 142, Indiana University, Bloomington, IN 47405 1847, USA
    J Bacteriol 186:4492-501. 2004
    ..tumefaciens surface interactions...
  22. ncbi request reprint Sociomicrobiology: the connections between quorum sensing and biofilms
    Matthew R Parsek
    Department of Microbiology, The University of Iowa, 540 EMRB, Iowa City, IA 52242 1109, USA
    Trends Microbiol 13:27-33. 2005
    ..Bacteria exhibit many social activities and they represent a model for dissecting social behavior at the genetic level. Therefore, we introduce the term 'sociomicrobiology'...
  23. ncbi request reprint The exopolysaccharide alginate protects Pseudomonas aeruginosa biofilm bacteria from IFN-gamma-mediated macrophage killing
    Jeff G Leid
    Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011, USA
    J Immunol 175:7512-8. 2005
    ..aeruginosa biofilm bacteria from the human immune system...
  24. doi request reprint Growing and analyzing biofilms in fermenters
    Bronwyn E Ramey
    University of Iowa, Iowa City, Iowa, USA
    Curr Protoc Microbiol . 2005
    ..These methods also utilize continuous culture, or chemostat, conditions to maintain a quasi-steady state...