A Mondragon

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi The structure of Escherichia coli DNA topoisomerase III
    A Mondragon
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208 3500, USA
    Structure 7:1373-83. 1999
  2. ncbi Protein-nucleotide interactions in E. coli DNA topoisomerase I
    H Feinberg
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwerstern University, 2153 Sheridan Road, Evanston, Illinois 60208, USA
    Nat Struct Biol 6:961-8. 1999
  3. ncbi Conformational changes in E. coli DNA topoisomerase I
    H Feinberg
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, 2153 Sheridan Road, Evanston, Illinois 60208, USA
    Nat Struct Biol 6:918-22. 1999
  4. ncbi Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule
    A Changela
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA
    Nature 411:1077-81. 2001
  5. ncbi Crystallization of a 67 kDa fragment of Escherichia coli DNA topoisomerase I
    C D Lima
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208
    J Mol Biol 232:1213-6. 1993
  6. ncbi Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
    C D Lima
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208
    Nature 367:138-46. 1994
  7. ncbi Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme
    A Changela
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, 2153 Sheridan Road, Evanston, IL 60208 3500, USA
    EMBO J 20:2575-86. 2001

Collaborators

  • A Changela
  • H Feinberg
  • C D Lima
  • R J DiGate
  • C K Ho
  • S Shuman
  • A Martins
  • J C Wang

Detail Information

Publications7

  1. ncbi The structure of Escherichia coli DNA topoisomerase III
    A Mondragon
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208 3500, USA
    Structure 7:1373-83. 1999
    ..Structural information on Escherichia coli DNA topoisomerase III is important for understanding the mechanism of this type of enzyme and for studying the mechanistic differences among different members of the same subfamily...
  2. ncbi Protein-nucleotide interactions in E. coli DNA topoisomerase I
    H Feinberg
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwerstern University, 2153 Sheridan Road, Evanston, Illinois 60208, USA
    Nat Struct Biol 6:961-8. 1999
    ..The positions of these sites allow us to identify different DNA binding regions and to understand their possible roles in the catalytic cycle...
  3. ncbi Conformational changes in E. coli DNA topoisomerase I
    H Feinberg
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, 2153 Sheridan Road, Evanston, Illinois 60208, USA
    Nat Struct Biol 6:918-22. 1999
    ..The fragment is composed of two domains, and while the domains themselves remain largely unchanged, their relative arrangement can change dramatically...
  4. ncbi Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule
    A Changela
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA
    Nature 411:1077-81. 2001
    ..These findings confirm various aspects of the type IA topoisomerase mechanism while suggesting functional implications for other topoisomerases and proteins that perform DNA rearrangements...
  5. ncbi Crystallization of a 67 kDa fragment of Escherichia coli DNA topoisomerase I
    C D Lima
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208
    J Mol Biol 232:1213-6. 1993
    ..A complete native data set and two derivative data sets have been collected. A multiple isomorphous replacement map to 3 A resolution shows clear secondary structural elements. Final structure determination is in progress...
  6. ncbi Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
    C D Lima
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208
    Nature 367:138-46. 1994
    ..The structure suggests a plausible mechanism by which E. coli DNA topoisomerase I and other members of the same DNA topoisomerase subfamily could catalyse the passage of one DNA strand through a transient break in another strand...
  7. ncbi Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme
    A Changela
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, 2153 Sheridan Road, Evanston, IL 60208 3500, USA
    EMBO J 20:2575-86. 2001
    ..Residues conserved uniquely among the RNA phosphatase subfamily are important for function in cap formation and are likely to play a role in substrate recognition...