M Mesulam

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi From sensation to cognition
    M M Mesulam
    Department of Neurology, Northwestern University Medical School, Chicago 60611, USA
    Brain 121:1013-52. 1998
  2. ncbi The cholinergic lesion of Alzheimer's disease: pivotal factor or side show?
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Learn Mem 11:43-9. 2004
  3. ncbi Primary progressive aphasia: reversed asymmetry of atrophy and right hemisphere language dominance
    M Mesulam
    Cognitive Neurology and Alzheimer s Disease Center and the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Neurology 64:556-7. 2005
  4. ncbi An update on primary progressive aphasia
    Emily Rogalski
    Cognitive Neurology and Alzheimer s Disease Center and Department of Neurology, Northwestern University, 320 E Superior Street, Searle Building 11 453, Chicago, IL 60657, USA
    Curr Neurol Neurosci Rep 7:388-92. 2007
  5. pmc Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events
    M M Mesulam
    Department of Neurology, Northwestern University Medical School, Chicago, IL 60611, USA
    Philos Trans R Soc Lond B Biol Sci 354:1325-46. 1999
  6. ncbi Primary progressive aphasia
    M M Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University, Chicago, IL 60611, USA
    Ann Neurol 49:425-32. 2001
  7. ncbi A large-scale distributed network for covert spatial attention: further anatomical delineation based on stringent behavioural and cognitive controls
    D R Gitelman
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University Medical School, Chicago, IL, USA
    Brain 122:1093-106. 1999
  8. ncbi Emotional curiosity: modulation of visuospatial attention by arousal is preserved in aging and early-stage Alzheimer's disease
    K S LaBar
    Department of Neurology, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, IL, USA
    Neuropsychologia 38:1734-40. 2000
  9. pmc Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Ann Neurol 63:709-19. 2008
  10. ncbi Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Ann Neurol 55:815-28. 2004

Collaborators

Detail Information

Publications17

  1. ncbi From sensation to cognition
    M M Mesulam
    Department of Neurology, Northwestern University Medical School, Chicago 60611, USA
    Brain 121:1013-52. 1998
    ..abstract truncated)..
  2. ncbi The cholinergic lesion of Alzheimer's disease: pivotal factor or side show?
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Learn Mem 11:43-9. 2004
    ..The cholinergic lesion may also influence the progression of the neuropathological process through complex interactions with amyloidogenesis, tau phosphorylation and neuroplasticity...
  3. ncbi Primary progressive aphasia: reversed asymmetry of atrophy and right hemisphere language dominance
    M Mesulam
    Cognitive Neurology and Alzheimer s Disease Center and the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Neurology 64:556-7. 2005
    ..This suggests that neuronal damage in PPA is therefore tightly linked to the underlying anatomy of the language network...
  4. ncbi An update on primary progressive aphasia
    Emily Rogalski
    Cognitive Neurology and Alzheimer s Disease Center and Department of Neurology, Northwestern University, 320 E Superior Street, Searle Building 11 453, Chicago, IL 60657, USA
    Curr Neurol Neurosci Rep 7:388-92. 2007
    ..This article reviews the clinical criteria for diagnosing primary progressive aphasia and some of the more recent research advances in this field...
  5. pmc Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events
    M M Mesulam
    Department of Neurology, Northwestern University Medical School, Chicago, IL 60611, USA
    Philos Trans R Soc Lond B Biol Sci 354:1325-46. 1999
    ..It helps to compile a mental representation of extrapersonal events in terms of their motivational salience, and to generate 'kinetic strategies' so that the attentional focus can shift from one target to another...
  6. ncbi Primary progressive aphasia
    M M Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University, Chicago, IL 60611, USA
    Ann Neurol 49:425-32. 2001
    ..An informed approach to this syndrome will increase the effectiveness with which clinicians can address the unique challenges associated with the diagnosis and care of PPA...
  7. ncbi A large-scale distributed network for covert spatial attention: further anatomical delineation based on stringent behavioural and cognitive controls
    D R Gitelman
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University Medical School, Chicago, IL, USA
    Brain 122:1093-106. 1999
    ..This temporo-occipital area appears to constitute a major component of the functional network activated by this spatial attention task. Its activation may reflect the 'inferred' shift of the attentional focus across the visual scene...
  8. ncbi Emotional curiosity: modulation of visuospatial attention by arousal is preserved in aging and early-stage Alzheimer's disease
    K S LaBar
    Department of Neurology, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, IL, USA
    Neuropsychologia 38:1734-40. 2000
    ..These results may have implications for interventions aimed at improving the cognitive symptoms of PRAD...
  9. pmc Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Ann Neurol 63:709-19. 2008
    ..To identify predictors of Alzheimer's disease (AD) versus frontotemporal lobar degeneration pathology in primary progressive aphasia (PPA), and determine whether the AD pathology is atypically distributed to fit the aphasic phenotype...
  10. ncbi Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Ann Neurol 55:815-28. 2004
    ..These results show that cytopathology in cortical cholinergic pathways is a very early event in the course of the continuum that leads from advanced age to MCI and AD...
  11. ncbi Widely spread butyrylcholinesterase can hydrolyze acetylcholine in the normal and Alzheimer brain
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Neurobiol Dis 9:88-93. 2002
    ..Butyrylcholinesterase (BChE), also known as the "pseudo" or "non-neuronal" cholinesterase, is traditionally thought to have a restricted CNS distribution and to play little, if any, role in cholinergic transmission...
  12. ncbi Cholinergic denervation in a pure multi-infarct state: observations on CADASIL
    Marsel Mesulam
    Cognitive Neurology and Alzheimer s Disease Center and the Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 60:1183-5. 2003
    ....
  13. ncbi Primary progressive aphasia pathology
    Marsel Mesulam
    Ann Neurol 63:124-5. 2008
  14. ncbi Anatomical physiology of spatial extinction
    Metehan Cicek
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Cereb Cortex 17:2892-8. 2007
    ....
  15. ncbi Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative
    Rosa Rademakers
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
    Lancet Neurol 6:857-68. 2007
    ..The most common mutation in GRN is Arg493X. We aimed to establish the contribution of this mutation to FTLD and related disorders...
  16. pmc Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives
    Emily Rogalski
    Neurological Sciences, Rush University Medical Center, 1735 W Harrison Street, Chicago, IL 60612, USA
    Arch Neurol 65:244-8. 2008
    ..Although risk factors for Alzheimer disease have been well studied, much less is known about risk factors for primary progressive aphasia (PPA)...
  17. pmc Association of GSK3B with Alzheimer disease and frontotemporal dementia
    Barbara A J Schaffer
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 2506 Gonda, 695 Charles E Young Dr S, Los Angeles, CA 90095 1761, USA
    Arch Neurol 65:1368-74. 2008
    ..As a known tau kinase, GSK3B is a promising candidate gene in the remaining cases of FTD and in AD, for which tau mutations have not been found...