Kevin McVary

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint A review of combination therapy in patients with benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    Clin Ther 29:387-98. 2007
  2. ncbi request reprint Editorial comment on: The natural history of Peyronie's disease: an ultrasonography-based study
    Kevin T McVary
    Eur Urol 53:650-1. 2008
  3. ncbi request reprint Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University Chicago, Illinois 60611, USA
    J Urol 174:1327-433. 2005
  4. ncbi request reprint Sildenafil citrate improves erectile function: a randomised double-blind trial with open-label extension
    K T McVary
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Int J Clin Pract 61:1843-9. 2007
  5. ncbi request reprint Interrelation of erectile dysfunction and lower urinary tract symptoms
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Drugs Today (Barc) 41:527-36. 2005
  6. ncbi request reprint Alfuzosin for symptomatic benign prostatic hyperplasia: long-term experience
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    J Urol 175:35-42. 2006
  7. ncbi request reprint Non-steroidal anti-inflammatory drugs and urinary retention
    Kevin T McVary
    Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Lancet 367:195-6. 2006
  8. ncbi request reprint Lower urinary tract symptoms and sexual dysfunction: epidemiology and pathophysiology
    Kevin McVary
    Northwestern University School of Medicine, Chicago, USA
    BJU Int 97:23-8; discussion 44-5. 2006
  9. ncbi request reprint BPH: epidemiology and comorbidities
    Kevin T McVary
    Northwestern University, Feinberg School of Medicine, Department of Urology, Chicago, IL 60611 3008, USA
    Am J Manag Care 12:S122-8. 2006
  10. ncbi request reprint Metabolic syndrome and lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Sanjay Kasturi
    Northwestern University Medical School, Department of Urology, Tarry 11 725, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Urol Rep 7:288-92. 2006

Research Grants

Collaborators

Detail Information

Publications52

  1. ncbi request reprint A review of combination therapy in patients with benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    Clin Ther 29:387-98. 2007
    ..The differing mechanisms of action and areas of efficacy of these 2 drug classes make them promising candidates for combination therapy...
  2. ncbi request reprint Editorial comment on: The natural history of Peyronie's disease: an ultrasonography-based study
    Kevin T McVary
    Eur Urol 53:650-1. 2008
  3. ncbi request reprint Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University Chicago, Illinois 60611, USA
    J Urol 174:1327-433. 2005
    ..We investigated the relationship of ANS activity to LUTS as well as to objective measures of BPH in men with BPH...
  4. ncbi request reprint Sildenafil citrate improves erectile function: a randomised double-blind trial with open-label extension
    K T McVary
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Int J Clin Pract 61:1843-9. 2007
    ..To evaluate once-daily 100-mg sildenafil for the treatment of erectile dysfunction (ED) in men with ED and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)...
  5. ncbi request reprint Interrelation of erectile dysfunction and lower urinary tract symptoms
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Drugs Today (Barc) 41:527-36. 2005
    ..Using Hill's causality method to separate causal from non-causal explanations linking ED with LUTS, it appears that most epidemiological components are fulfilled...
  6. ncbi request reprint Alfuzosin for symptomatic benign prostatic hyperplasia: long-term experience
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    J Urol 175:35-42. 2006
    ..Evidence of the long-term efficacy and safety of alfuzosin treatment for LUTS indicative of BPH was examined...
  7. ncbi request reprint Non-steroidal anti-inflammatory drugs and urinary retention
    Kevin T McVary
    Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Lancet 367:195-6. 2006
  8. ncbi request reprint Lower urinary tract symptoms and sexual dysfunction: epidemiology and pathophysiology
    Kevin McVary
    Northwestern University School of Medicine, Chicago, USA
    BJU Int 97:23-8; discussion 44-5. 2006
    ..Studies treating one condition (e.g. ED) and measuring the impact on the other (e.g. LUTS) should further contribute to support this common link...
  9. ncbi request reprint BPH: epidemiology and comorbidities
    Kevin T McVary
    Northwestern University, Feinberg School of Medicine, Department of Urology, Chicago, IL 60611 3008, USA
    Am J Manag Care 12:S122-8. 2006
    ..When selecting an appropriate course of therapy, these side effects and any impact they may have on existing comorbid conditions must be considered...
  10. ncbi request reprint Metabolic syndrome and lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Sanjay Kasturi
    Northwestern University Medical School, Department of Urology, Tarry 11 725, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Urol Rep 7:288-92. 2006
    ....
  11. ncbi request reprint Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, double-blind trial
    Kevin T McVary
    Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    J Urol 177:1071-7. 2007
    ..We evaluated sildenafil for erectile dysfunction and lower urinary tract symptoms in men with the 2 conditions...
  12. ncbi request reprint Erectile dysfunction and lower urinary tract symptoms secondary to BPH
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University Medical School, Tarry 16 749, 303 E Chicago Ave, Chicago, IL 60611, USA
    Eur Urol 47:838-45. 2005
    ..The association between these two diseases has also garnered attention as investigators have hypothesized a common pathophysiology to explain the assertion that they are causally linked...
  13. ncbi request reprint Clinical practice. Erectile dysfunction
    Kevin T McVary
    Northwestern University Feinberg School of Medicine, Department of Urology, Chicago, IL 60611, USA
    N Engl J Med 357:2472-81. 2007
  14. doi request reprint Update on AUA guideline on the management of benign prostatic hyperplasia
    Kevin T McVary
    American Urological Association Education and Research, Inc, Linthicum Maryland, USA
    J Urol 185:1793-803. 2011
    ..To revise the 2003 version of the American Urological Association's (AUA) Guideline on the management of benign prostatic hyperplasia (BPH)...
  15. ncbi request reprint Medical therapy for benign prostatic hyperplasia progression
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, Tarry Building Room 11 715, 303 East Chicago Avenue, Chicago, IL 60611 3008, USA
    Curr Urol Rep 3:269-75. 2002
    ..Interestingly, finasteride and combination therapy reduced the long-term risk of acute urinary retention...
  16. doi request reprint Sildenafil citrate improves erectile function and lower urinary tract symptoms independent of baseline body mass index or LUTS severity
    Kevin T McVary
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    Urology 72:575-9. 2008
    ..To evaluate the body mass index (BMI) and lower urinary tract symptom (LUTS) severity on treatment response to sildenafil in men with erectile dysfunction (ED) and moderate to severe LUTS associated with benign prostatic hyperplasia...
  17. ncbi request reprint Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Urol 177:1401-7. 2007
    ..We assessed the efficacy and safety of tadalafil dosed once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia...
  18. doi request reprint Identifying patients with benign prostatic hyperplasia through a diagnosis of, or treatment for, erectile dysfunction
    Kevin McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University School of Medicine, Chicago, IL 60611, USA
    Curr Med Res Opin 24:775-84. 2008
    ..Multivariate analyses were used to examine times to screening, diagnosis, and treatment...
  19. ncbi request reprint The relationship between erectile dysfunction and lower urinary tract symptoms: epidemiological, clinical, and basic science evidence
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Tarry 16 749, Chicago, IL 60611, USA
    Curr Urol Rep 5:251-7. 2004
    ..The association is supported by the consistent linear relationship of more severe LUTS with more severe ED. The link between ED and LUTS has biologic plausibility given the four leading theories of how these diseases inter-relate...
  20. ncbi request reprint Lower urinary tract symptoms, benign prostatic hyperplasia, and obesity
    Anne K Mongiu
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Curr Urol Rep 10:247-53. 2009
    ..Future studies may lead to office detection of a patient's particular polymorphisms, which may help guide individual treatment and lifestyle modifications that are more likely to succeed...
  21. doi request reprint Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 180:1228-34. 2008
    ..Preliminary data have suggested phosphodiesterase type 5 inhibitor efficacy in men with lower urinary tract symptoms associated with clinical benign prostatic hyperplasia...
  22. ncbi request reprint The role of combination therapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Chris M Gonzalez
    Department of Urology, Northwestern University Medical School, 303 E Chicago Ave, Tarry 11 715, Chicago, IL 60611, USA
    Curr Urol Rep 4:276-81. 2003
  23. ncbi request reprint Posterior Hox gene expression in developing genitalia
    Carol Podlasek
    Department of Urology, Northwestern University Medical School, Chicago, IL 60611, USA
    Evol Dev 4:142-63. 2002
  24. ncbi request reprint Erectile function, sexual drive, and ejaculatory function after reconstructive surgery for anterior urethral stricture disease
    Bradley A Erickson
    Department of Urology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    BJU Int 99:607-11. 2007
    ..To evaluate the effect of urethral reconstructive surgery on sexual drive, erectile function and ejaculation...
  25. ncbi request reprint Altered Sonic hedgehog signaling is associated with morphological abnormalities in the penis of the BB/WOR diabetic rat
    Carol A Podlasek
    Departments of Urology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Biol Reprod 69:816-27. 2003
    ..Increasing our understanding of the molecular mechanisms that regulate Shh signaling may provide valuable insight into improving treatment options for diabetic impotence...
  26. pmc Regulation of cavernous nerve injury-induced apoptosis by sonic hedgehog
    Carol A Podlasek
    Department of Urology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Biol Reprod 76:19-28. 2007
    ..These results show that SHH stabilizes the alterations of the corpora cavernosal smooth muscle following nerve injury...
  27. ncbi request reprint Sonic hedgehog cascade is required for penile postnatal morphogenesis, differentiation, and adult homeostasis
    Carol A Podlasek
    Department of Urology and Physiology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Biol Reprod 68:423-38. 2003
    ..These studies provide valuable insight that may be applied to improve treatment options for erectile dysfunction...
  28. ncbi request reprint Penile weight and cell subtype specific changes in a post-radical prostatectomy model of erectile dysfunction
    Herbert M User
    Department of Urology, Northwestern University Medical School, Chicago, Illinois, USA
    J Urol 169:1175-9. 2003
    ..We investigated changes in DNA, protein and apoptotic cells of the rat penis after denervation. Gross morphometry was measured to elucidate the impact of chemical changes...
  29. doi request reprint Holmium laser prostatic resection for patients presenting with acute urinary retention
    Christopher B Anderson
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    BJU Int 102:1623-8. 2008
    ....
  30. doi request reprint Established medical therapy for benign prostatic hyperplasia
    Gregory B Auffenberg
    Department of Urology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Tarry 16 703, Chicago, IL 60611 3008, USA
    Urol Clin North Am 36:443-59, v-vi. 2009
    ..The available clinical trial data for all of these types of therapy is discussed in this article...
  31. doi request reprint Consequences of switching 5alpha-reductase inhibitors on prostate specific antigen velocity
    Brian T Helfand
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Urol 184:218-23. 2010
    ..We examined prostate specific antigen velocity after changes in 5alpha-reductase inhibitor formularies...
  32. doi request reprint Lower urinary tract symptoms, obesity and the metabolic syndrome
    Samdeep Moul
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    Curr Opin Urol 20:7-12. 2010
    ..The epidemic of obesity and concomitant metabolic syndrome is well documented. New evidence points to a connection between the components of metabolic syndrome and benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS)...
  33. ncbi request reprint Management of lower urinary tract symptoms secondary to benign prostatic hyperplasia with open prostatectomy: results of a contemporary series
    Brian Helfand
    Department of Urology, Feinberg School of Medicine, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, IL 60611, USA
    J Urol 176:2557-61; discussion 2561. 2006
    ....
  34. ncbi request reprint Topical agents and erectile dysfunction: is there a place?
    Ronald L Yap
    Department of Urology, Northwestern University Medical School, Tarry 11 725, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Urol Rep 3:471-6. 2002
    ..Although still in the investigative stage, topical medications can be another tool in the urologist's armamentarium against ED...
  35. ncbi request reprint Lower urinary tract symptoms and erectile dysfunction: epidemiology and treatment in the aging man
    Shane Russell
    Northwestern University Feinberg School of Medicine, Department of Urology, Tarry Building, Room 16 749, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Urol Rep 6:445-53. 2005
    ..This newly recognized independent relationship between ED and LUTS has the potential to have a profound impact on the way we diagnose and treat these common urologic disorders...
  36. ncbi request reprint Microarray analysis and description of SMR1 gene in rat penis in a post-radical prostatectomy model of erectile dysfunction
    Herbert M User
    Department of Urology, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, IL 60611, USA
    J Urol 170:298-301. 2003
    ..We attempted to identify previously undescribed molecular changes via gene discovery methods using GeneChip (Affymetrix, Santa Clara, California) microarray technology...
  37. doi request reprint Alpha-blockers and intraoperative floppy iris syndrome: ophthalmic adverse events following cataract surgery
    Zuhair K Al-Hussaini
    Department of Urology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 16 703, Chicago, IL 60611 3008, USA
    Curr Urol Rep 11:242-8. 2010
    ..There is still much to learn about IFIS and its exact causes, as well as a need for agreed upon guidelines that would enable physicians to properly anticipate and successfully manage or even prevent the condition...
  38. doi request reprint Preoperative clinical and diagnostic characteristics of patients who require delayed IPP after primary Peyronies repair
    Hannah H Alphs
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL60611 3008, USA
    J Sex Med 7:1262-8. 2010
    ..However, precisely which parameters can be used to predict those patients with PD at risk for developing erectile dysfunction (ED) after intervention without inflatable penile prosthesis (IPP) has not been previously elucidated...
  39. ncbi request reprint Holmium laser ablation and enucleation of the prostate: a pilot study of the hybrid technique
    Brian T Helfand
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    Can J Urol 17:5190-4. 2010
    ....
  40. doi request reprint Prospective analysis of ejaculatory function after anterior urethral reconstruction
    Bradley A Erickson
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    J Urol 184:238-42. 2010
    ..We prospectively evaluated the effects of urethral reconstruction on ejaculatory function...
  41. doi request reprint Medications and surgical interventions for benign prostatic hyperplasia are potential confounders of prostate-specific antigen
    Parth Modi
    Department of Urology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 16 703, Chicago, IL 60611, USA
    Curr Urol Rep 11:224-7. 2010
    ....
  42. doi request reprint Determining the utility of recalled lower urinary tract symptoms
    Brian T Helfand
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 3008, USA
    Urology 76:442-7. 2010
    ..The AUA-SI is a validated questionnaire used to assess a patient's lower urinary tract symptoms (LUTS) over a 4-week period. However, patient recall of their LUTS at greater time points is currently unknown...
  43. doi request reprint Phytotherapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Raj C Dedhia
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Urol 179:2119-25. 2008
    ....
  44. doi request reprint Variation in institutional review board responses to a standard protocol for a multicenter randomized, controlled surgical trial
    Brian T Helfand
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Urol 181:2674-9. 2009
    ....
  45. doi request reprint Postoperative PSA and PSA velocity identify presence of prostate cancer after various surgical interventions for benign prostatic hyperplasia
    Brian T Helfand
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinios 60611, USA
    Urology 74:177-83. 2009
    ..Although the PSA level can be used for CaP screening in this population, it might be influenced by the efficacies of different BPH procedures...
  46. ncbi request reprint Impact of phytotherapy on utility scores for 5 benign prostatic hyperplasia/lower urinary tract symptoms health states
    Raj C Dedhia
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Urol 179:220-5. 2008
    ....
  47. ncbi request reprint Unexpected insights into pelvic function following phosphodiesterase manipulation--what's next for urology?
    Kevin T McVary
    Eur Urol 50:1153-6. 2006
  48. ncbi request reprint The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    John D McConnell
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    N Engl J Med 349:2387-98. 2003
    ..The long-term effect of these drugs, singly or combined, on the risk of clinical progression is unknown...
  49. ncbi request reprint Beneficial effects of extended-release doxazosin and doxazosin standard on sexual health
    Steven A Kaplan
    Columbia University, New York, NY, USA
    BJU Int 97:559-66. 2006
    ..Increasing clinical evidence attests to the effectiveness of doxazosin in relieving ED, even in patients refractory to ED-specific treatment, as well as in reducing BPH symptoms and elevated blood pressure...
  50. ncbi request reprint Urologic complications of diabetes
    Jeanette S Brown
    University of California, San Francisco, San Francisco, California 94115, USA
    Diabetes Care 28:177-85. 2005
  51. ncbi request reprint The clinical significance of residual urine--how much is too much and when should a urologist start treatment?
    Kevin T McVary
    J Urol 180:14. 2008
  52. doi request reprint Correlation of the International Prostate Symptom Score bother question with the Benign Prostatic Hyperplasia Impact Index in a clinical practice setting
    MICHAEL P O'LEARY
    Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    BJU Int 101:1531-5. 2008
    ....

Research Grants12

  1. The Efficacy of TUMT and Neoadjuvant Finasteride for BPH
    Kevin McVary; Fiscal Year: 2005
    ..We are proposing a 3-arm, placebo/sham controlled, randomized clinical trial using changes in symptoms as the primary ..
  2. Saw palmetto and Pygeum africanum on BPH Progression
    Kevin McVary; Fiscal Year: 2004
    ..Secondary Aim: Unique to this submission is whether a chief complaint analysis, sleep scale measures or direct/indirect healthcare costs analysis provides reliable or useful information. ..
  3. N O S AND NEUROPATHIC AND ENDOTHELIAL INDUCED ED
    Kevin McVary; Fiscal Year: 2002
    ..Results of this research will aid in the understanding of how diabetic neuropathy contributes to sexual dysfunction and elucidate possible mechanisms to prevent them. ..
  4. REGULATION OF PROSTATE GROWTH BY NEURAL FACTORS
    Kevin McVary; Fiscal Year: 2001
    ..Using this model allows one to explore the limits of understanding prostatic neuroregulation, to explore neurotrophic influences on exocrine gland development, and to possibly uncover novel methods to influence prostate disease. ..