Research Topics
| T W McDadeSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
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Detail Information
Publications
What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based researchThomas W McDade
Northwestern University, Department of Anthropology and Cells to Society C2S The Center on Social Disparities and Health at the Institute for Policy Research, 1810 Hinman Avenue, Evanston, IL 60208, USA
Demography 44:899-925. 2007..Our objective is to provide investigators with the information they need to make informed decisions regarding the appropriateness of blood spot methods for their research interests...
Early environments and the ecology of inflammationThomas W McDade
Department of Anthropology and Cells to Society The Center on Social Disparities and Health at the Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Proc Natl Acad Sci U S A 109:17281-8. 2012..Attention to the eco-logics of inflammation may point to promising directions for future research, enriching our understanding of this important physiological system and informing approaches to the prevention and treatment of disease...
Quantification of anti-Müllerian hormone (AMH) in dried blood spots: validation of a minimally invasive method for assessing ovarian reserveThomas W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Hum Reprod 27:2503-8. 2012..This paper validates a new method for quantifying AMH in dried blood spot (DBS) samples--drops of whole blood collected on filter paper following a simple finger stick...
Analysis of variability of high sensitivity C-reactive protein in lowland Ecuador reveals no evidence of chronic low-grade inflammationThomas W McDade
Department of Anthropology, Northwestern University, Evanston, Illinois, USA
Am J Hum Biol 24:675-81. 2012..Prior analyses of CRP variability have reported stable between-individual differences in CRP over time, but a limitation of current knowledge is that it is based on research conducted in post-epidemiologic transition populations...
Evaluating indices of traditional ecological knowledge: a methodological contributionVictoria Reyes-García
ICREA and ICTA, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
J Ethnobiol Ethnomed 2:21. 2006..Few studies have addressed reliability of indices of traditional ecological knowledge constructed with different quantitative methods...
Cytomegalovirus antibodies in dried blood spots: a minimally invasive method for assessing stress, immune function, and agingJennifer B Dowd
Epidemiology and Biostatistics, Hunter College, CUNY School of Public Health, 425 E, 25th St, New York, NY 10010, USA
Immun Ageing 8:3. 2011..abstract:..
Rationale and methodological options for assessing infectious disease and related measures in social science surveysThomas W McDade
Northwestern University, Department of Anthropology, Cells to Society The Center on Social Disparities and Health at the Institute for Policy Research, Evanston, Illinois 60208, USA
Biodemography Soc Biol 55:159-77. 2009..These methods afford opportunities for innovative, transdisciplinary research on the causes and consequences of infectious disease across the life course that can address questions of interest to social, life, and biomedical scientists...
Maintenance versus growth: investigating the costs of immune activation among children in lowland BoliviaT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Am J Phys Anthropol 136:478-84. 2008....
Positive antibody response to vaccination in adolescence predicts lower C-reactive protein concentration in young adulthood in the PhilippinesThomas W McDade
Department of Anthropology, Northwestern University, Evanston, Illinois 60208, USA
Am J Hum Biol 23:313-8. 2011..This study investigates the within-individual association between antibody response to vaccination in adolescence and C-reactive protein (CRP) concentration in young adulthood...
Population differences in associations between C-reactive protein concentration and adiposity: comparison of young adults in the Philippines and the United StatesThomas W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Am J Clin Nutr 89:1237-45. 2009....
Early origins of inflammation: microbial exposures in infancy predict lower levels of C-reactive protein in adulthoodThomas W McDade
Department of Anthropology, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Proc Biol Sci 277:1129-37. 2010....
Predictors of C-reactive protein in the national social life, health, and aging projectThomas W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
J Gerontol B Psychol Sci Soc Sci 66:129-36. 2011....
Adolescents' expectations for the future predict health behaviors in early adulthoodThomas W McDade
Cells to Society C2S The Center on Social Disparities and Health, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Soc Sci Med 73:391-8. 2011..Perceived life chances in adolescence may therefore play an important role in establishing individual trajectories of health, and in contributing to social gradients in population health...
Comparative insights into the regulation of inflammation: levels and predictors of interleukin 6 and interleukin 10 in young adults in the PhilippinesThomas W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Am J Phys Anthropol 146:373-84. 2011....
Ethnobotanical knowledge is associated with indices of child health in the Bolivian AmazonT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Proc Natl Acad Sci U S A 104:6134-9. 2007..These results underscore the importance of local cultural factors to child health and document a potential cost if ethnobotanical knowledge is lost...
Life history, maintenance, and the early origins of immune functionThomas W McDade
Laboratory for Human Biology Research, Department of Anthropology, Northwestern University, Evanston, Illinois 60208, USA
Am J Hum Biol 17:81-94. 2005..Ecologically-informed research on immunity is in its earliest stages, and life history theory has the potential to make important contributions to our understanding of the development and function of this critical physiological system...
Life history theory and the immune system: steps toward a human ecological immunologyThomas W McDade
Department of Anthropology, Northwestern University, Evanston, Illinois 60208, USA
Am J Phys Anthropol . 2003..Research in human ecological immunology is in its earliest stages, but this is a promising area of exploration, and one in which anthropology is well-positioned to make important contributions...
Whole blood collected on filter paper provides a minimally invasive method for assessing human transferrin receptor levelThomas W McDade
Laboratory for Human Biology Research, Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
J Nutr 132:3760-3. 2002..The advantages and disadvantages of the blood spot TfR method are discussed, as well as its potential contribution to future field-based studies of iron deficiency...
High-sensitivity enzyme immunoassay for C-reactive protein in dried blood spotsThomas W McDade
Laboratory for Human Biology Research, Northwestern University, Evanston, IL 60208, USA
Clin Chem 50:652-4. 2004
Prenatal and early postnatal environments are significant predictors of total immunoglobulin E concentration in Filipino adolescentsT W McDade
Laboratory for Human Biology Research, Department of Anthropology, Northwestern University, Evanston, IL 60208 1310, USA
Clin Exp Allergy 34:44-50. 2004..Few studies have been able to evaluate these associations simultaneously, or to investigate prospectively the long-term effects of early environments while adequately controlling for potentially confounding variables...
Status incongruity in Samoan youth: a biocultural analysis of culture change, stress, and immune functionThomas W McDade
Department of Anthropology, Northwestern University, USA
Med Anthropol Q 16:123-50. 2002..This study proposes new conceptual models for future studies of culture change and suggests that biomarkers may represent ethnographic tools that can provide insight into hidden cultural dynamics and the experience of stress...
Predictors of C-reactive protein in Tsimane' 2 to 15 year-olds in lowland BoliviaT W McDade
Laboratory for Human Biology Research, Department of Anthropology, Northwestern University, Evanston, Illinois 60208, USA
Am J Phys Anthropol 128:906-13. 2005..The measurement of CRP offers a direct, objective indicator of immune activation, and provides insights into a potentially important pathway through which environmental quality may shape child growth and health...
Lifestyle incongruity, social integration, and immune function in Samoan adolescentsT W McDade
Northwestern University, Department of Anthropology, Evanston, IL 60208, USA
Soc Sci Med 53:1351-62. 2001..The potential utility of the lifestyle incongruity model for future cross-cultural studies of child and adolescent stress is discussed...
Prenatal undernutrition, postnatal environments, and antibody response to vaccination in adolescenceT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Am J Clin Nutr 74:543-8. 2001..Recently, researchers have considered the fetal and infant origins of several adult cardiovascular and metabolic diseases, but the implications of early events for immune function and infectious disease are unclear...
Psychosocial and behavioral predictors of inflammation in middle-aged and older adults: the Chicago health, aging, and social relations studyThomas W McDade
Department of Anthropology, Northwestern University, 1810 Hinman Avenue, Evanston, Illinois 60208 1310, USA
Psychosom Med 68:376-81. 2006..We investigated the contribution of behavioral and psychosocial factors to variation in CRP concentrations in a population-based sample of middle-aged and older adults...
Defining the "urban" in urbanization and health: a factor analysis approachT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Soc Sci Med 53:55-70. 2001..This analysis demonstrates the heterogeneity of environments within urban and rural areas, and emphasizes the need for a finer level of investigation in future studies of urbanization and health...
Prenatal undernutrition and postnatal growth are associated with adolescent thymic functionT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208 1310, USA
J Nutr 131:1225-31. 2001..These findings provide support for the importance of fetal and early infant programming of thymic function, and suggest that early environments may have long-term implications for immunocompetence and adult disease risk...
Influence of helminth infections on childhood nutritional status in lowland BoliviaS Tanner
Department of Anthropology, University of Georgia, Athens, Georgia 30602 1619, USA
Am J Hum Biol 21:651-6. 2009..These data demonstrate the difficulty of assessing nutritional impacts of endemic infections...
Epstein-Barr virus antibodies in whole blood spots: a minimally invasive method for assessing an aspect of cell-mediated immunityT W McDade
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Psychosom Med 62:560-7. 2000..Study 2: Apply this method to a large community-based study of psychopathology in children and adolescents...
Change in waist circumference over 11 years and current waist circumference independently predict elevated CRP in Filipino womenJulienne N Rutherford
Department of Oral Biology, College of Dentistry, University of Illinois at Chicago, 801 S Paulina Street, Chicago, Illinois, USA
Am J Hum Biol 22:310-5. 2010..Although current waist circumference is an important contributor to risk of elevated systemic inflammation in this as in other populations, history of central adiposity may be an independent phenomenon...
Adiposity and pathogen exposure predict C-reactive protein in Filipino womenThomas W McDade
Department of Anthropology, The Center on Social Disparities and Health at the Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
J Nutr 138:2442-7. 2008..These results underscore the need for additional research on the contributions of pathogenicity, adiposity, and inflammation to global epidemics of cardiovascular and metabolic diseases...
Rapid weight gain after birth predicts life history and reproductive strategy in Filipino malesChristopher W Kuzawa
Department of Anthropology and Cells to Society, Center on Social Disparities and Health at the Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Proc Natl Acad Sci U S A 107:16800-5. 2010..These findings provide evidence for early life developmental plasticity in male life history and reproductive strategy in humans...
Inflammatory mediators and glucose in pregnancy: results from a subset of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) StudyLynn P Lowe
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1400, Chicago, Illinois 60611, USA
J Clin Endocrinol Metab 95:5427-34. 2010..Inflammatory mediators are associated with type 2 and gestational diabetes. It is unknown whether there are associations with glucose in pregnant women with lesser degrees of hyperglycemia...
The relationship between self-report and biomarkers of stress in low-income reproductive-age womenAnn E B Borders
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Am J Obstet Gynecol 203:577.e1-8. 2010..The purpose of this study was to determine whether there is an association between self-reported and biologic measures of stress in low-income, reproductive-age women...
Mothers have lower testosterone than non-mothers: evidence from the PhilippinesChristopher W Kuzawa
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Horm Behav 57:441-7. 2010....
Breastfeeding as obesity prevention in the United States: a sibling difference modelMolly W Metzger
Department of Human Development and Social Policy, Northwestern University, 2046 Sheridan Road, Evanston, IL 60208, USA
Am J Hum Biol 22:291-6. 2010..The application of a sibling fixed-effects model provides stronger evidence of a causal relationship than prior research reporting similar patterns of association...
Fatherhood, pairbonding and testosterone in the PhilippinesChristopher W Kuzawa
Northwestern University, Department of Anthropology, Evanston, IL 60208, USA
Horm Behav 56:429-35. 2009....
Measurement of leptin in dried blood spot samplesAaron A Miller
Department of Anthropology, Northwestern University, Evanston, Illinois 60208, USA
Am J Hum Biol 18:857-60. 2006..Thus, care should be taken to refrigerate or freeze samples promptly. The relative ease of blood spot sample collection may facilitate research on leptin in a wider range of cultural and ecological settings...
Developmental changes in the relationship between leptin and adiposity among Tsimané children and adolescentsKatherine C B Sharrock
Department of Anthropology, Harvard University, Cambridge, Massachusetts 02138, USA
Am J Hum Biol 20:392-8. 2008..These findings suggest a more important role of leptin as a signal of energy stores among females as they approach reproductive maturity, while raising questions about the function of this hormone in lean males...
Evaluation of iron deficiency as a nutritional adaptation to infectious disease: an evolutionary medicine perspectiveKatherine Wander
Department of Anthropology, University of Washington, Seattle, Washington 98195, USA
Am J Hum Biol 21:172-9. 2009..11). Controlling for age and TSF, the OR for infection associated with an unequivocally iron replete state (compared to all others) was 2.9 (P = 0.01). We conclude that iron deficiency may protect against acute infection in children...
Relationships between skin color, income, and blood pressure among African Americans in the CARDIA StudyElizabeth Sweet
Department of Anthropology, Northwestern University, Evanston, Ill 60208, USA
Am J Public Health 97:2253-9. 2007..We explored how income and skin color interact to influence the blood pressure of African American adults enrolled in the longitudinal Coronary Artery Risk Development in Young Adults (CARDIA) Study...
Anthropometric correlates of C-reactive protein among indigenous SiberiansJ Josh Snodgrass
Department of Anthropology, University of Oregon, Eugene 97403, USA
J Physiol Anthropol 26:241-6. 2007..Positive associations were documented between CRP and BMI, body fat, and central adiposity...
The use of dried blood spot sampling in the national social life, health, and aging projectSharon R Williams
Department of Anthropology, Purdue University, 700 West State Street, West Lafayette, IN 47907, USA
J Gerontol B Psychol Sci Soc Sci 64:i131-6. 2009....
Lifestyle incongruity, stress and immune function in indigenous Siberians: the health impacts of rapid social and economic changeMark V Sorensen
Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516 3115, USA
Am J Phys Anthropol 138:62-9. 2009..The findings also suggest that relative, as opposed to absolute, level of economic status or material wealth is more strongly related to stress in the Siberian context...
Enzyme immunoassay for total immunoglobulin E in dried blood spotsSusan Tanner
Department of Anthropology, University of Georgia, Athens, Georgia 30602, USA
Am J Hum Biol 19:440-2. 2007..It is hoped that the relative ease of blood spot collection will expand opportunities for population-based research on IgE...
The effect of rainfall during gestation and early childhood on adult height in a foraging and horticultural society of the Bolivian AmazonRicardo Godoy
Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts 02454, USA
Am J Hum Biol 20:23-34. 2008..2% lower adult height (1.08-1.93 cm). Environmental perturbations that take place after the cessation of weaning seem to leave the strongest effect on adult height. We advance possible explanations for the absence of effects among males...
On the accuracy of perceived parental height in a native Amazonian societyAnkur M Patel
Heller School for Social Policy and Management, Brandeis University, Waltham, MA 02454 9110, USA
Econ Hum Biol 5:165-78. 2007..We discuss possible reasons for the low accuracy of Tsimane' estimates...
Research Grants
- Social Influences on Early Adult Stress BiomarkersTHOMAS MC DADE; Fiscal Year: 2007....
- Social Influences on Early Adult Stress BiomarkersTHOMAS MC DADE; Fiscal Year: 2009..abstract_text> ..
- Social Influences on Early Adult Stress BiomarkersTHOMAS W MC DADE; Fiscal Year: 2010..abstract_text> ..
