T W McDade


Affiliation: Northwestern University
Country: USA


  1. McDade T, Hoke M, Borja J, Adair L, Kuzawa C. Do environments in infancy moderate the association between stress and inflammation in adulthood? Initial evidence from a birth cohort in the Philippines. Brain Behav Immun. 2013;31:23-30 pubmed publisher
  2. McDade T, Borja J, Kuzawa C, Perez T, Adair L. C-reactive protein response to influenza vaccination as a model of mild inflammatory stimulation in the Philippines. Vaccine. 2015;33:2004-8 pubmed publisher
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    McDade T, Beck M, Kuzawa C, Adair L. Prenatal undernutrition, postnatal environments, and antibody response to vaccination in adolescence. Am J Clin Nutr. 2001;74:543-8 pubmed
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    McDade T. Life history theory and the immune system: steps toward a human ecological immunology. Am J Phys Anthropol. 2003;Suppl 37:100-25 pubmed
    ..Research in human ecological immunology is in its earliest stages, but this is a promising area of exploration, and one in which anthropology is well-positioned to make important contributions. ..
  5. McDade T, Rutherford J, Adair L, Kuzawa C. Population differences in associations between C-reactive protein concentration and adiposity: comparison of young adults in the Philippines and the United States. Am J Clin Nutr. 2009;89:1237-45 pubmed publisher
  6. McDade T, Rutherford J, Adair L, Kuzawa C. Early origins of inflammation: microbial exposures in infancy predict lower levels of C-reactive protein in adulthood. Proc Biol Sci. 2010;277:1129-37 pubmed publisher
  7. McDade T, Tallman P, Madimenos F, Liebert M, Cepon T, Sugiyama L, et al. Analysis of variability of high sensitivity C-reactive protein in lowland Ecuador reveals no evidence of chronic low-grade inflammation. Am J Hum Biol. 2012;24:675-81 pubmed publisher
    ..These results may have substantial implications for research on inflammation and diseases of aging globally, as well as for scientific understandings of the regulation of inflammation. ..
  8. McDade T, Georgiev A, Kuzawa C. Trade-offs between acquired and innate immune defenses in humans. Evol Med Public Health. 2016;2016:1-16 pubmed publisher
  9. McDade T, Borja J, Largado F, Adair L, Kuzawa C. Adiposity and Chronic Inflammation in Young Women Predict Inflammation during Normal Pregnancy in the Philippines. J Nutr. 2016;146:353-7 pubmed publisher

More Information


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    McDade T, Hawkley L, Cacioppo J. Psychosocial and behavioral predictors of inflammation in middle-aged and older adults: the Chicago health, aging, and social relations study. Psychosom Med. 2006;68:376-81 pubmed
    ..Psychosocial stress, as well as health behaviors, are important predictors of inflammatory activity in a population-based sample and should be considered in future research on inflammation and CVD. ..
  2. McDade T, Ryan C, Jones M, Macisaac J, Morin A, Meyer J, et al. Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood. Proc Natl Acad Sci U S A. 2017;114:7611-7616 pubmed publisher
    ..This pattern of results points toward DNAm as a potentially important biological mechanism through which developmental environments shape inflammatory phenotypes across the life course. ..